Luana dos Santos Ortolan

@seattlechildrens.org

Research Scientist III at Center for Global and Infectious Disease
Seattle Children's Research Institute

https://researchid.co/luanaortolan

RESEARCH, TEACHING, or OTHER INTERESTS

Infectious Diseases, Immunology and Microbiology, Neuroscience

301

Scholar Citations

Scholar h-index

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

Single-cell analysis of Szary syndrome reveals novel markers and shifting gene profiles associated with treatment
N Borcherding, KJ Severson, N Henderson, LS Ortolan, AC Rosenthal, ...
Blood advances 7 (3), 321-335 2023

Lines Expressing DC8 and Group A PfEMP1 Bind to Brain, Intestinal, and Kidney Endothelial Cells
LS Ortolan, M Avril, J Xue, KB Seydel, Y Zheng, JD Smith
Models to study malaria parasite-host cell interactions and pathogenesis 2022

051 Exogenous IL-27 prevents disease induction in murine alopecia areata
P Christy, S Crotts, SJ Connell, M Lensing, L Ortolan, N Henderson, X Bai, ...
Journal of Investigative Dermatology 142 (8), S9 2022

Blockade of caspase cascade overcomes malaria-associated acute respiratory distress syndrome in mice
MK Sercundes, LS Ortolan, V da Silva Julio, LM Bella, T de Castro Quirino, ...
Cell Death & Disease 13 (2), 144 2022

Plasmodium falciparum parasite lines expressing DC8 and Group A PfEMP1 bind to brain, intestinal, and kidney endothelial cells
LS Ortolan, M Avril, J Xue, KB Seydel, Y Zheng, JD Smith
Frontiers in Cellular and Infection Microbiology 12, 813011 2022

CD4 T cell-mediated induction of alopecia areata is dose dependent and requires CD8 T cells
SJ Connell, S Crotts, P Christy, L Ortolan, N Henderson, A Jabbari
The Journal of Immunology 206 (1_Supplement), 21.14-21.14 2021

020 Induction of hair loss by expanded CD4 T cells from previously affected AA mice
SJ Connell, S Crotts, P Christy, L Ortolan, N Henderson, A Jabbari
Journal of Investigative Dermatology 141 (5), S4 2021

070 Comprehensive single-cell analysis of Szary syndrome reveals novel expression and therapeutic biomarkers
N Borcherding, N Henderson, L Ortolan, V Liu, B Link, A Mangold, ...
Journal of Investigative Dermatology 141 (5), S12 2021

Perillyl alcohol reduces parasite sequestration and cerebrovascular dysfunction during experimental cerebral malaria
AA Marin, O Murillo, RA Sussmann, LS Ortolan, DS Battagello, ...
Antimicrobial Agents and Chemotherapy 65 (5), 10.1128/aac. 00004-21 2021

Comprehensive Single-Cell Analysis of Peripheral Blood in Sezary Syndrome Reveals Novel Expression Markers and Shifting Gene Profiles Associated with Treatment
N Borcherding, N Henderson, L Ortolan, V Liu, B Link, A Mangold, ...
LABORATORY INVESTIGATION 101 (SUPPL 1), 287-287 2021

Perillyl alcohol reduces parasite sequestration and cerebrovascular dysfunction during experimental cerebral malaria
AAM Rodriguez, O Murillo, RAC Sussmann, LS Ortolan, DS Battagello, ...
Antimicrobial Agents and Chemotherapy 65 (5), 1-14 2021

Single-Cell mRNA Sequencing of Murine and Human Alopecia Areata Identifies Immune Cell Profiles Predictive of Human Disease State
N Borcherding, S Crotts, L Ortolan, N Bormann, A Jabbari
American Journal of Clinical Pathology 154, S5 2020

A transcriptomic map of murine and human alopecia areata
N Borcherding, SB Crotts, LS Ortolan, N Henderson, NL Bormann, ...
JCI insight 5 (13) 2020

Lung aeration in experimental malaria-associated acute respiratory distress syndrome by SPECT/CT analysis
TC Quirino, LS Ortolan, MK Sercundes, CRF Marinho, WM Turato, ...
Plos one 15 (5), e0233864 2020

Endothelial protein C receptor could contribute to experimental malaria-associated acute respiratory distress syndrome
L dos Santos Ortolan, MK Sercundes, GC Moura, T de Castro Quirino, ...
Journal of Immunology Research 2019 2019

IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans
LS Ortolan, SR Kim, S Crotts, LY Liu, BG Craiglow, C Wambier, ...
Journal of allergy and clinical immunology 144 (6), 1731-1734. e1 2019

Endothelial protein C receptor contributes to experimental malaria-associated acute respiratory distress syndrome
L Ortolan, M Sercundes, G Moura, T Quirino, D Debone, D Costa, ...
EUROPEAN JOURNAL OF IMMUNOLOGY 49, 1204-1204 2019

Research Article Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome
L dos Santos Ortolan, MK Sercundes, GC Moura, T de Castro Quirino, ...
2019

105 Neutralization of IL-12 and IL-23 does not prevent experimental alopecia areata
L Ortolan, S Crotts, A Jabbari
Journal of investigative dermatology 139 (5), S18-S18 2019

099 CD4 T cells require CD8 T cells to induce disease in murine alopecia areata
S Crotts, L Ortolan, A Jabbari
Journal of investigative dermatology 139 (5), S17-S17 2019

MOST CITED SCHOLAR PUBLICATIONS

Targeting neutrophils to prevent malaria-associated acute lung injury/acute respiratory distress syndrome in mice
MK Sercundes, LS Ortolan, D Debone, PV Soeiro-Pereira, E Gomes, ...
PLoS Pathogens 12 (12), e1006054 2016
Citations: 103

Association of heme oxygenase 1 with lung protection in malaria-associated ALI/ARDS
MLM Pereira, LS Ortolan, MK Sercundes, D Debone, O Murillo, FA Lima, ...
Mediators of Inflammation 2016 2016
Citations: 40

Predictive criteria to study the pathogenesis of malaria-associated ALI/ARDS in mice
LS Ortolan, MK Sercundes, R Barboza, D Debone, O Murillo, SCF Hagen, ...
Mediators of Inflammation 2014 2014
Citations: 33

A transcriptomic map of murine and human alopecia areata
N Borcherding, SB Crotts, LS Ortolan, N Henderson, NL Bormann, ...
JCI insight 5 (13) 2020
Citations: 29

Inhibition of hypoxia-associated response and kynurenine production in response to hyperbaric oxygen as mechanisms involved in protection against experimental cerebral malaria
MF Bastos, ACAV Kayano, JL Silva-Filho, JCK Dos-Santos, C Judice, ...
The FASEB Journal 32 (8), 4470 2018
Citations: 9

Survey of Plasmodium in the golden-headed lion tamarin (Leontopithecus chrysomelas) living in urban Atlantic forest in Rio de Janeiro, Brazil
EH Aitken, MG Bueno, L dos Santos Ortolan, JM Alvarz, A Pissinatti, ...
Malaria Journal 15, 1-6 2016
Citations: 8

Correction: targeting neutrophils to prevent malaria-associated acute lung injury/acute respiratory distress syndrome in mice
MK Sercundes, LS Ortolan, D Debone, PV Soeiro-Pereira, E Gomes, ...
PLoS Pathogens 13 (11), e1006730 2017
Citations: 6

Physiopathology of malaria-associated acute respiratory distress syndrome
G Cndido Moura, D Barcelos, S Epiphanio, LD Santos Ortolan
J Infect Dis Preve Med 5 (171), 2 2017
Citations: 6

Inflammatory factors and leucocytes are involved in the pathogenesis of malaria associated acute lung injury/acute respiratory distress syndrome in murine model
MK Sercundes, LD Ortolan, D Debone, EH Aitken, JM Alvarez, M Russo, ...
Front Immunol 4 2013
Citations: 2

Citoadeso na imunopatognese da sndrome do desconforto respiratrio agudo associado malria.
LS Ortolan
Universidade de So Paulo 2017
Citations: 1