Felicia Esemekiphoraro Williams

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacy, Public Health, Environmental and Occupational Health, Oncology, Epidemiology

Scopus Publications

Safety measures in the workplace: a case study of Federal Road Safety Corps (FRSC) vehicle plate manufacturing plant, Ojodu – Lagos, Nigeria
David U Adje, Chisom Judith Anyalebechi, and Felicia E Williams
Nepal Journals Online (JOL)
Introduction: Hazards associated with vehicle number plate manufacturing processes in developing countries have not been well elucidated. There is a need to investigate hazards in the vehicle number plate manufacturing plant. The study aimed to identify self-reported hazards in the vehicle plate manufacturing factory, explore their effect on workers’ health and recommend mitigation strategies. Methods: A descriptive cross-sectional study of workers in the vehicle plate manufacturing plant was done to identify hazards, protective measures and self-reported effects on workers’ health. Biochemical analysis of blood samples was also done and outliers were noted. ANOVA test was performed to determine differences in mean values of selected biochemical parameters. A p-value of less than 0.05 was considered statistically significant. Results: Exposure to toxic chemicals 38(69%), excessive noise 36 (65%) and heat 28 (51%) were the major hazards in the factory. Major health problems were stress and fatigue 41 (71%), skin disorders 28 (51%), respiratory problems 18 (33%) and hearing loss 16 (29%). More than one quarter, 17 (30 %) of the workers admitted not using personal protective equipment (PPE) regularly. Periodic medical tests were not done for 13 (24%) of the workers. Potassium (3%), Urea (10%),   Creatinine (7%), Aspartate transaminase (18%) and Alanine transaminase (8%) were elevated among the workers but no significant association could be established between elevated levels and work post. Conclusion: Workers in the plate number manufacturing plant were mostly exposed to toxic chemicals and noise. Elevated electrolyte levels cut across departments.   There is a need for better enforcement of safety rules, and periodic medical examinations should be conducted more consistently.


Assessment of the perception of the public on the impact of the lockdown due to the Coronavirus Disease 2019 (COVID-19)
Awofisayo O, Ologunagba MO, Williams FE, Joda AE, Ibrahim MB, Olugbake OA, Ayeni FA, Oyetunde OO, and Mosanya AU
Nigerian Medical Association, Akwa Ibom State Branch
Background: Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 started in Wuhan, China in December 2019 and was declared pandemic by the World Health Organization (WHO) in March 2020. Globally, majority of nations worldwide with Nigeria inclusive were on lockdown. Variations exist in the way the public responded to the lockdown.Objective: The study is to determine the public perception on the impact of the lockdown due to COVID-19Methods: Pretested survey form prepared using the Google form app and distributed via social media - WhatsApp, Facebook, email and Instagram. Sample size was determined as 510. The data collected was exported to Microsoft Excel. Descriptive and inferential statistics were used. Inferential analysis was done using chi square, and fisher exact test at 95% confidence interval. Ethical approval was obtained from the University of Uyo Teaching Hospital Health Research and Ethics Committee, Uyo, Akwa Ibom State, Nigeria.Results: A total of 510 respondents participated in the study. The results revealed 52.2% female respondents. The data revealed 60% were employed with majority residing in the South Western part of Nigeria and are in a relationship. While self-employed participants comprised 25.9%. Respondents aged between 40-49 years were 28.6%, while 61.57% were postgraduate degree holders. The current data showed that 59.6% of the respondents think that the lockdown, irrespective of the dimension taken prevented the spread of the diseaseConclusion: A significant percentage of the public are of the opinion that the lockdown was effective.


Outcome of cardiovascular risk assessment among rural community dwellers in ezionum, Nigeria-implications for public health
David U Adje, Felicia E Williams, and Azuka C Oparah
African Journals Online (AJOL)
Background Cardiovascular disease is a major cause of mortality worldwide. Risk assessment has been shown to reduce cardiovascular morbidity and mortality. In view of their proximity and accessibility, community pharmacies could be a suitable site for cardiovascular risk assessment and other preventive health activities especially in rural underserved populations. The objective of this study was to assess outcome of cardiovascular risk assessment among rural community dwellers. Materials and methods Five hundred and five community dwellers aged 40 to 80 years were recruited for the study. Cardiovascular risk assessment was performed using the region specific WHO/ISH risk assessment charts. Blood pressure, diabetes status, total non- fasting cholesterol, and age were used to estimate risk category. Demographic variables and clinical characteristics were expressed as frequency and percentage. Regression analysis was done to identify predictors of high risk category. Results More than 30% of subjects were hypertensive. Nearly 30% were overweight and had abnormal cholesterol levels. The proportion of subjects in the high risk category was 8.9%. Systolic blood pressure, random blood sugar and advancing age were the highest predictors of high risk category. Conclusion Accessibility, proximity and availability are unique characteristics of community pharmacies that could be exploited to support community based screening services.


Assessment of the preventive health content of pharmacy curriculum in Nigerian universities




Antidiarrhoeal activity of Musa paradisiaca sap in wistar rats
Musa T. Yakubu, Quadri O. Nurudeen, Saoban S. Salimon, Monsurat O. Yakubu, Rukayat O. Jimoh, Mikhail O. Nafiu, Musbau A. Akanji, Adenike T. Oladiji, and Felicia E. Williams
Hindawi Limited
The folkloric claim ofMusa paradisiacasap in the management of diarrhoea is yet to be substantiated or refuted with scientific data. Therefore, the aim of the current study was to screen the sap ofM. paradisiacafor both its secondary metabolites and antidiarrhoeal activity at 0.25, 0.50, and 1.00 mL in rats. Secondary metabolites were screened using standard methods while the antidiarrhoeal activity was done by adopting the castor oil-induced diarrhoeal, castor oil-induced enteropooling, and gastrointestinal motility models. The sap contained flavonoids, phenolics, saponins, alkaloids, tannins, and steroids while cardiac glycosides, anthraquinones, triterpenes, cardenolides, and dienolides were not detected. In the castor oil-induced diarrhoeal model, the sap significantly (P<0.05) prolonged the onset time of diarrhoea, decreased the number, fresh weight, and water content of feaces, and increased the inhibition of defecations. Na+-K+-ATPase activity in the small intestine increased significantly whereas nitric oxide content decreased. The decreases in the masses and volumes of intestinal fluid by the sap were accompanied by increase in inhibition of intestinal fluid content in the enteropooling model. The sap decreased the charcoal meal transit in the gastrointestinal motility model. In all the models, the 1.00 mL of the sap produced changes that compared well with the reference drugs. Overall, the antidiarrhoeal activity ofMusa paradisiacasap attributed to the presence of alkaloids, phenolics, flavonoids, and/or saponins which may involve, among others, enhancing fluid and electrolyte absorption throughde novosynthesis of the sodium potassium ATPase and/or reduced nitric oxide levels.


Towards validating moringa's nutraceutical benefits: An examination of consumers' perspectives vis-à-vis health benefits efficacy and willingness to pay

RECENT SCHOLAR PUBLICATIONS

Safety measures in the workplace: a case study of Federal Road Safety Corps (FRSC) vehicle plate manufacturing plant, Ojodu–Lagos, Nigeria
DU Adje, CJ Anyalebechi, FE Williams
International Journal of Occupational Safety and Health 14 (2), 247-258 2024



Assessment of HBV-HIV coinfection among HIV patients on antiretroviral therapy in secondary care hospitals in a NorthCentral Senatorial District, Nigeria
F Williams, D Adje, W Giwa, JF John-Benson, L Odeigah
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 31, 677-677 2022



Pharmacists' knowledge and practice with respect to coronavirus disease 2019 caused by SARS-CoV-2
OA Olugbake, AU Mosanya, FA Ayeni, AE Joda, OO Oyetunde, ...
The Nigerian Journal of Pharmacy 56 (1), 119-127| https://doi. org/10.51412 2022



Assessment of the perception of the public on the impact of the lockdown due to the Coronavirus Disease 2019 (COVID-19)
O Awofisayo, MO Ologunagba, FE Williams, AE Joda, MB Ibrahim, ...
Ibom Medical Journal 15 (1), 24-31 2022



Assessment of the second and third" 90" strategies to end HIV/AIDS pandemic at secondary care hospitals in a senatorial district, North-Central Nigeria
F Williams, S Bello, D Adje, A Abdulkareem
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 30, 437-438 2021



Prevalence of chronic kidney disease in patients with type 2 diabetes mellitus attending a secondary care hospital in north central Nigeria
FO Aliyu
Journal of Pharmaceutical Research, Development and Practice 2021



Female Sexual Dysfunction in Women Attending the Lentiviral Clinic at the University of Ilorin Teaching Hospital, Ilorin, Nigeria
LO Odeigah, AE Fawibe, MT Bolarin, IA Obalowu, YB Mutalub, ...
NIGERIAN JOURNAL OF FAMILY PRACTICE 2021



Pharmacists’ perception of their roles and involvement in coronavirus disease 2019 (covid-19)
AE Joda, OA Olugbake, OO Oyetunde, O Awofisayo, MB Ibrahim, ...
Journal of Basic and Social Pharmacy Research 2020



Pharmacists’ perception of their roles and involvement in coronavirus disease 2019 (covid-19)
AE Joda, OA Olugbake, OO Oyetunde, O Awofisayo, MB Ibrahim, ...
Journal of Basic and Social Pharmacy Research 2020



Medicine Dispensing Pattern in Management of HIV/AIDS Patients at Public Health Facilities in a North-Central State, Nigeria
FE WILLIAMS, AO AWOYEMI, DB PARAKOYI, ET JOLAYEMI, ...
Asian Journal of Pharmaceutical and Health Sciences 10 (2) 2020



Diabetes Mellitus and Hypertension among Patients on Combination Antiretroviral Therapy in Civil Service Hospital, Nigeria
SI Bello, F Williams, N Bello, MA Ajulo, AA Yusuf, HG Lawal
Bangladesh Pharmaceutical Journal 2020



Availability and Utilization of Drug Information Center, Drugs and Therapeutic Committee and Standard Treatment Guidelines in the Management of HIV/AIDS Patients at Public
FE Williams, AO Awoyemi, DB Parakoyi, ET Jolayemi, TM Akande
Nigerian Journal of Pharmaceutical Research 15 (1), 27-34 2019



Prevalence of use of Erectile dysfunction drugs among youths in Delta State, Nigeria
UD Adje, A R.O., FE Williams, JO Eti
Pakistan Journal of Pharmaceutical Research 5 (1), 1 - 7 2019



Viral Hepatitis B Infection among Undergraduate Students Accessing Health Services at Public Tertiary Institution in Kwara South, Nigeria.
SI Bello, FE Williams, FO Aliyu, WA Ojieabu, MA Adewumi
Journal of Basic and Social Pharmacy Research 2019



Outcome of cardiovascular risk assessment among rural community dwellers in ezionum, Nigeria-implications for public health
DU Adje, FE Williams, AC Oparah
African Health Sciences 19 (2), 2112-2120 2019



Assessment of ART knowledge and adherence to ARVs among PLWHA accessing care in two Nigerian Military HIV/AIDS Treatment sites
DU Adje, FE Williams, CN Bezugbe, DA Dangiwa
Annals of Health Research 4 (1), 43-52 2018



Assessment of the preventive health content of pharmacy curriculum in Nigerian universities.
D Adje, F Williams, J Arute, A Oparah, D Dangiwa, H Olele
Pharmacy Education 18, 151-156 2018



Prescription of Antineoplastic Agents in Management of Breast Cancer Patients at a Tertiary Hospital in North-Central Nigeria
FE Williams, SO Agodirin, SI Bello, NO Bello, HK Jimoh
Journal of Pharmaceutical Research Development and Practice 2 (2), 52 - 60 2018



Medicine Use Among Hiv/Aids Patients in Public Hospitals, Kwara State
FE Williams, AO Awoyemi, DB Parakoyi, ET Jolayemi, TM Akande
Nigerian Journal of Pharmaceutical Research 13 (1), 53-64 2017



Outcome of Pharmacists Health Belief Perception and Knowledge of CVD Risk Factors Intervention among Rural Community Dwellers
D Adje, A Oparah, F Williams
Journal of Pharmaceutical Research International 18 (2), 1-10 2017

MOST CITED SCHOLAR PUBLICATIONS

Antidiarrhoeal activity of Musa paradisiaca Sap in Wistar rats
MT Yakubu, QO Nurudeen, SS Salimon, MO Yakubu, RO Jimoh, ...
Evidence-Based Complementary and Alternative Medicine 2015 2015
Citations: 64



Nutritional characterization of grain amaranth grown in Nigeria for food security and healthy living
GT Abolaji, FM Olooto, DT Ogundele, FE Williams
Agrosearch 17 (2), 1-10 2017
Citations: 23



Towards validating Moringa’s nutraceutical benefits: An examination of consumers’ perspectives vis--vis health benefits efficacy and willingness to pay
JO Animashaun, FE Williams, AA Toye
Agris on-line Papers in Economics and Informatics 5 (2), 11-21 2013
Citations: 19



Effects of Moringa Oleifera (Drumstick) Leaf Extracts on Lead-Induced Testicular Toxicity In Adult Wistar Rat (Rattus Novergicus)
JO Owolabi, OK Ghazal, FE Williams, EO Ayodele
Int J Biotech Biomed Res 2 (12), 4003-4009 2012
Citations: 16



Phytochemical screening and acute toxicity studies of crude ethanolic extract and flavonoid fraction of Carissa edulis leaves
H Ibrahim, FE Williams, KM Salawu, AM Usman
Biokemistri 27 (1), 39-43 2015
Citations: 13



Histomorphological Evidences of Moringa oleifera's Ameliorative Effects against Lead Toxicity in Cerebral Cortex
J OWOLABI, F WILLIAM, J OLANREWAJU, T ETIBOR, O FABIYI
World Journal of Life Sciences and Medical Research 3 (2), 53 2014
Citations: 13



Evaluation of Moringa's Effects Against Lead-Induced Disruption of the Hippocampus in Animal Models
J OWOLABI, F WILLIAMS, O FABIYI
World Journal of Life Sciences and Medical Research 3 (2), 39 2014
Citations: 8



Preliminary Survey on Consumption of Moringa Products for Nutraceutical Benefits in Ilorin, Kwara State, Nigeria.
FE Williams, JO Animashaun, H Ibrahim, AA Toye
Agrosearch 13 (1), 165-178 2013
Citations: 8



Ameliorative effects of Adansonia digitata leaf extract on carbon tetrachloride (CCl4) induced testicular toxicity in adult male wistar rats
OA Oyetunji, IR Babatunde, SL Chia, OA Abraham, FB Adewale, ...
Anatomy Journal of Africa 4 (1), 481–487-481–487 2015
Citations: 7



Outcome of cardiovascular risk assessment among rural community dwellers in ezionum, Nigeria-implications for public health
DU Adje, FE Williams, AC Oparah
African Health Sciences 19 (2), 2112-2120 2019
Citations: 6



Assessment of point of care testing services in community pharmacies in Delta State, Nigeria
DU Adje, AC Oparah, FE Williams, OO Ezeagwuna
Journal of Science and Practice of Pharmacy 3 (1), 115 -120 2016
Citations: 6



Prophylactic and regenerative effects of alcoholic extract of moringa oleifera on lead-induced lung tissue damage in adult male wistar rats models
J Owolabi, O Ghazal, M Dare, J Olanrewaju, A Caxton-Martins, F William
Eur. j. anat, 115-122 2013
Citations: 6



Prophylactic and regenerative effects of alcoholic extract of Moringa oleifera on rat lung tissue following lead-induced damage
J Owolabi, O Ghazal, M Dare, J Olanrewaju, A Caxton-Martins, F William
European Journal of Anatomy 17 (2), 115-22 2013
Citations: 6



Assessment of the prophylactic and rejuvenative effects of moringa oleifera phytochemicals extracts on lead-induced renal tissue disruption in adults male wistar rats models
JO Owolabi, OK Ghazal, FE Williams, OO Gurusa
Proceedings of the Moringa at the Leading Edge: International Conference on 2012
Citations: 5



Effects of Ethanolic Extract of Moringa Oleifera Leaves On Lead Acetate Induced Liver Damage In Adult Wistar Rats
OK Ghazal, JO Owolabi, FE William, E Lambe
International Journal of Biotechnology and Biomedical Research 2 (1) 2012
Citations: 5



Assessment of the preventive health content of pharmacy curriculum in Nigerian universities.
D Adje, F Williams, J Arute, A Oparah, D Dangiwa, H Olele
Pharmacy Education 18, 151-156 2018
Citations: 4



Pharmacists’ perception of their roles and involvement in coronavirus disease 2019 (covid-19)
AE Joda, OA Olugbake, OO Oyetunde, O Awofisayo, MB Ibrahim, ...
Journal of Basic and Social Pharmacy Research 2020
Citations: 3



OUTCOMES OF COMMUNITY PHARMACIST’CARDIOVASCULAR RISK INTERVENTION AMONG HIGH RISK RURAL DWELLERS
UD Adje, CA Oparah, FE Williams, E Akpovwovwo
International Journal of Pharmaceutical Sciences and Research 8 (12), 5353 2017
Citations: 3



Availability of Antiretroviral and Non-Antiretroviral Medicines in the Management of HIV/AIDS Patients in Public Hospitals in a North-Central State of Nigeria
ETJTMA Felicia Esemekiphoraro WILLIAMS, Ademola Olugbenga AWOYEMI, Dauda ...
West African Journal of Pharmacy 28 (1), 129 - 140 2017
Citations: 3



Hibiscus sabdariffa L. drink improves postural stress-induced myocardial oxygen consumption changes in young adult men and women
TO Usman, O Akintoye, VA Olatunji, FE Williams, LA Olatunji
Nigerian Journal of Experimental and Clinical Biosciences 2 (2), 109 2014
Citations: 3