Cardiology and Cardiovascular Medicine, Signal Processing, Biomedical Engineering, Multidisciplinary
65
Scopus Publications
572
Scholar Citations
14
Scholar h-index
19
Scholar i10-index
Scopus Publications
Musician presence and its effects on physiological and psychological well-being in live versus livestreamed concerts Antonia S. Becker, Julia Peters, Mathijs S. van Schie, Julian Schaap, Koen van Eijck, et al. Scientific Reports, 2026 Listening to music, whether live or prerecorded, can benefit health and well-being. Studies have shown that music can alleviate pain and anxiety, improve emotional well-being, and strengthen social connectedness. While research on live music is promising, direct comparisons with recorded settings—specifically in relation to the physical co-presence of performing musicians—are limited. In this randomized controlled pilot study (n = 130), we examined the effects of live music concerts (classical and pop) compared to a simultaneous cinematic livestream, in a parallel design. Psychological and physiological well-being were assessed through self-reported questionnaires and physiological measures, including heart rate (HR) and heart rate variability (HRV). In the live condition, participants reported greater appreciation for the music, felt more moved by the music as indicated by higher kama muta scores, and reported higher arousal and valence compared to the livestream condition. Using linear mixed models, we found that only the mean HR was significantly higher in the live group, whereas other HRV parameters did not show statistically significant differences. In conclusion, the “liveness”—in terms of the musicians being physical present—emerges as an important aspect shaping audience’s subjective experiences and physiological responses, particularly HR.
Men and women’s hearts don’t beat the same: Epicardial mapping of Bachmann’s bundle Anouk I. Freriks, Nicole L. M. de Kruijf, Mathijs S. van Schie, Vehpi Yildirim, Paul Knops, et al. Netherlands Heart Journal, 2025 Background There is increasing evidence that presentation, progression, and management of atrial arrhythmias, such as atrial fibrillation (AF), differ between women and men. Bachmann’s bundle (BB) is the main route for interatrial conduction, and sex-related differences in structural and electrical remodeling of BB may contribute to differences in AF development between women and men. Objective Investigate whether sex differences in the electrophysiological properties of BB assessed by high-resolution and density maps exist in patients with AF. Methods Sinus rhythm at BB was recorded for 5 s during cardiac surgery. Potential voltage, low-voltage area (LVA), conduction heterogeneity, unipolar potential morphology, and conduction velocity were assessed for both men and women. Results The study population consisted of 108 patients (73 men, 35 women). Women had significantly lower potential voltages (5th percentile: 0.7 mV [0.6–1.0] vs 1.1 mV [0.6–1.4], p = 0.028), more LVAs (10.8% [4.6–19.7] vs 4.3% [2.2–11.7], p = 0.012) and more long double potentials (11.1% [3.6–13.5] vs 5.0% [1.0–10.3], p = 0.015) compared to men. Conclusions We observed sex-related differences in the electrical remodeling of BB in AF patients. Women have a higher proportion of low voltage potentials, and more abnormal potential morphologies compared to men. These findings may reflect sex-specific differences in the underlying substrate of AF at BB.
Early Currents: Developmental Electrophysiology and Arrhythmia in Pediatric Congenital Heart Disease Lixia Dai, Weilin Liu, Vehpi Yildirim, Mathijs S. van Schie, Yannick J. H. J. Taverne, et al. Journal of Cardiovascular Development and Disease, 2025 Arrhythmias significantly contribute to morbidity and mortality in patients with congenital heart disease (CHD). While postoperative factors predisposing to arrhythmias are well-established, early electrophysiological alterations in pediatric CHD remain poorly understood. This review summarizes current knowledge on postnatal cardiac maturation, conduction-system development, and electrophysiological abnormalities in pediatric patients with and without CHD. Importantly, arrhythmia prevalence, mechanisms, and clinical relevance are systematically discussed across three pediatric groups, including healthy children and patients with unrepaired and repaired CHD. Understanding developmental arrhythmogenic mechanisms may facilitate early risk stratification, guide clinical management decisions, and improve long-term outcomes for pediatric patients with CHD. This review discusses the complex interplay between cardiac maturation, congenital defects, and arrhythmogenesis. It also outlines future directions that include noninvasive monitoring, selective intraoperative mapping, animal model studies, and standardized data collection to improve early risk stratification and long-term outcomes in children with CHD.
Leadless pacing: a comprehensive review Shmaila Saleem-Talib, Crispijn P R Hoevenaars, Nadine Molitor, Vincent J van Driel, Jeroen van der Heijden, et al. European Heart Journal, 2025
Atrial electrophysiological characteristics of aging Willemijn F.B. van der Does, Charlotte A. Houck, Annejet Heida, Mathijs S. van Schie, Frank R.N. van Schaagen, et al. Journal of Cardiovascular Electrophysiology, 2021
The Irregularity Factor: Mechanistic Insights into Beat-to-beat Irregularities in Atrial Fibrillation Cycle Length NMS de Groot, LN van Staveren, EAH Lanters, V Yildirim, R Hendriks, ... Heart Rhythm , 2026 2026
Characterization of Paroxysmal Atrial Fibrillation in Atrial Septal Defects: Contribution of a Left Atrial Substrate C Zhang, NLR Misier, YJHJ Taverne, HH Nguyen, MS van Schie, L Dai, ... JACC: Clinical Electrophysiology , 2026 2026
PO-03-052 ATRIAL FOCUSED ELECTROCARDIOGRAMS ANALYSIS ENHANCES AUTOMATED RHYTHM DETECTION NL de Kruijf, MS van Schie, M De Boer, Y Taverne, M Kavousi, ... Heart Rhythm 23 (4), S529 , 2026 2026
PO-03-042 PERFORMANCE ANALYSIS OF QRS DETECTORS ON REAL-LIFE CONTINUOUS RHYTHM MONITORING SURFACE ELECTROCARDIOGRAMS NL de Kruijf, M De Boer, R Tieleman, Y Taverne, M Kavousi, NM De Groot, ... Heart Rhythm 23 (4), S524 , 2026 2026
PO-04-257 RIGHT ATRIAL CONDUCTION DISORDERS INFLUENCE BACHMANN’S BUNDLE ENTRY PATTERNS A Freriks, J Zheng, MS van Schie, V Yildirim, F Oei, F van Schaagen, ... Heart Rhythm 23 (4), S742 , 2026 2026
PO-04-222 THE IMPACT OF ATRIAL DILATATION ON CONDUCTION HETEROGENEITY AT BACHMANN'S BUNDLE A Freriks, MH Linderhof, D Veen, A Heida, Y Taverne, H Ramanna, ... Heart Rhythm 23 (4), S726-S727 , 2026 2026
Characterization of radiofrequency ablation lesions by high-density unipolar, bipolar and omnipolar voltage mapping MS van Schie, H Xiang, P Knops, FRN van Schaagen, LM Vos, FBS Oei, ... Heart Rhythm , 2026 2026
Strain detects substrate: Pioneering non-invasive visualization of atrial electropathology MHC Linderhof, AI Freriks, ECH van Doorn, C Zhang, L Dai, HH Nguyen, ... International Journal of Cardiology, 134261 , 2026 2026
Musician presence and its effects on physiological and psychological well-being in live versus livestreamed concerts AS Becker, J Peters, MS van Schie, J Schaap, K van Eijck, M Berghman, ... Scientific Reports , 2026 2026 Citations: 1
Inferior sino-atrial node exit sites are associated with electrical remodeling J Zheng, MS van Schie, L Dai, P Knops, J Kluin, YJHJ Taverne, ... Clinical Electrophysiology 12 (2), 251-260 , 2026 2026 Citations: 1
Assessing ASD arrhythmogenic substrate using atrial strain echocardiography: a prognostic tool? MHC Linderhof, AI Freriks, ECH Van Doorn, MS Van Schie, Y Taverne, ... European Heart Journal-Cardiovascular Imaging 27 (Supplement_1), jeaf367. 306 , 2026 2026
Intraoperative Sino-Atrial Node Mapping in Left Atrial Isomerism: A Proof-of-Concept Study to Avoid Surgical Injury NLR Misier, YYHY Taverne, MS van Schie, PC van de Woestijne, ... JACC: Clinical Electrophysiology , 2025 2025
Spatial and temporal dispersion of ventricular repolarization in pediatric patients with congenital long-QT syndrome L Dai, C Zhang, NLR Misier, MS van Schie, L Bear, M Haissaguerre, ... HeartRhythm Case Reports , 2025 2025
Men and women’s hearts don’t beat the same: Epicardial mapping of Bachmann’s bundle AI Freriks, NLM De Kruijf, MS Van Schie, V Yildirim, P Knops, LM Vos, ... Netherlands Heart Journal 33 (12), 421-428 , 2025 2025 Citations: 3
Small patients, significant findings: electropathology of Bachmann Bundle in pediatric patients N De Groot, L Dai, C Zhang, A Freriks, M Lindermans, H Nguyen, J Zheng, ... European Heart Journal 46 (Supplement_1), ehaf784. 4037 , 2025 2025
Mapping the unseen: Programmed electrical stimulation to detect concealed conduction block R Liao, L Zhang, P Knops, Z Ye, YJHJ Taverne, J Kluin, V Yildirim, ... Heart Rhythm , 2025 2025
Early Currents: Developmental Electrophysiology and Arrhythmia in Pediatric Congenital Heart Disease L Dai, W Liu, V Yildirim, MS van Schie, YJHJ Taverne, NMS de Groot Journal of Cardiovascular Development and Disease 12 (10), 386 , 2025 2025 Citations: 1
Ebstein Anomaly and Atrial Conduction: Big Does Not Mean Bad NL Ramdat Misier, MS van Schie, PC van de Woestijne, HH Nguyen, ... Circulation: Arrhythmia and Electrophysiology 18 (9), e014119 , 2025 2025 Citations: 1
Age in aortic disease: The path towards atrial fibrillation NLM de Kruijf, AI Freriks, MS van Schie, P Knops, V Yildirim, ... Translational Medicine of Aging , 2025 2025
Intraoperative Sino-Atrial Node Mapping in Left Atrial Isomerism: A Proof-of-Concept Study to Avoid Surgical Injury NL Ramdat Misier, YYHY Taverne, MS van Schie, PC van de Woestijne, ... Clinical Electrophysiology , 2025 2025
MOST CITED SCHOLAR PUBLICATIONS
Identification of local atrial conduction heterogeneities using high-density conduction velocity estimation MS Van Schie, A Heida, YJHJ Taverne, AJJC Bogers, NMS De Groot EP Europace 23 (11), 1815-1825 , 2021 2021 Citations: 53
Identification of low-voltage areas: a unipolar, bipolar, and omnipolar perspective MS van Schie, RK Kharbanda, CA Houck, EAH Lanters, YJHJ Taverne, ... Circulation: Arrhythmia and Electrophysiology 14 (7), e009912 , 2021 2021 Citations: 38
Leadless pacing: a comprehensive review S Saleem-Talib, CPR Hoevenaars, N Molitor, VJ van Driel, ... European Heart Journal 46 (21), 1979-1990 , 2025 2025 Citations: 34
Sinus rhythm voltage fingerprinting in patients with mitral valve disease using a high-density epicardial mapping approach MS Van Schie, R Starreveld, AJJC Bogers, NMS De Groot EP Europace 23 (3), 469-478 , 2021 2021 Citations: 30
Digital biomarkers and algorithms for detection of atrial fibrillation using surface electrocardiograms: A systematic review FJ Wesselius, MS van Schie, NMS De Groot, RC Hendriks Computers in Biology and Medicine 133, 104404 , 2021 2021 Citations: 29
Classification of sinus rhythm single potential morphology in patients with mitral valve disease MS van Schie, R Starreveld, MC Roos-Serote, YJHJ Taverne, ... EP Europace 22 (10), 1509-1519 , 2020 2020 Citations: 25
Atrial electrophysiological characteristics of aging WFB van der Does, CA Houck, A Heida, MS van Schie, ... Journal of Cardiovascular Electrophysiology 32 (4), 903-912 , 2021 2021 Citations: 24
Reduction of conduction velocity in patients with atrial fibrillation A Heida, MS van Schie, WFB van der Does, YJHJ Taverne, AJJC Bogers, ... Journal of Clinical Medicine 10 (12), 2614 , 2021 2021 Citations: 22
Degree of fibrosis in human atrial tissue is not the hallmark driving AF K S. Ramos, L Pool, MS van Schie, LFJM Wijdeveld, WFB van der Does, ... Cells 11 (3), 427 , 2022 2022 Citations: 19
Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial PR Kappen, MI Mos, J Jeekel, CMF Dirven, SA Kushner, RJ Osse, ... BMJ open 13 (6), e069957 , 2023 2023 Citations: 18
Endo-epicardial mapping of in vivo human sinoatrial node activity RK Kharbanda, FJ Wesselius, MS van Schie, YJHJ Taverne, AJJC Bogers, ... Clinical Electrophysiology 7 (6), 693-702 , 2021 2021 Citations: 17
Characterization of pre-existing arrhythmogenic substrate associated with de novo early and late postoperative atrial fibrillation MS Van Schie, D Veen, RK Kharbanda, A Heida, R Starreveld, ... International Journal of Cardiology 363, 71-79 , 2022 2022 Citations: 16
Premature atrial contractions promote local directional heterogeneities in conduction velocity vectors MS van Schie, NL Ramdat Misier, P Razavi Ebrahimi, A Heida, ... Europace 25 (3), 1162-1171 , 2023 2023 Citations: 14
Analyzing the effect of electrode size on electrogram and activation map properties B Abdi, MS van Schie, NMS de Groot, RC Hendriks Computers in Biology and Medicine 134, 104467 , 2021 2021 Citations: 14
Signal fingerprinting as a novel diagnostic tool to identify conduction inhomogeneity Z Ye, MS van Schie, NMS de Groot Frontiers in physiology 12, 652128 , 2021 2021 Citations: 14
Low-voltage potentials contribute to postoperative atrial fibrillation development in obese patients C Schram-Serban, MS van Schie, P Knops, C Kik, AJJC Bogers, ... Heart Rhythm 19 (5), 710-718 , 2022 2022 Citations: 12
First evidence of atrial conduction disorders in pediatric patients with congenital heart disease RK Kharbanda, MS van Schie, NL Ramdat Misier, WJ van Leeuwen, ... Clinical Electrophysiology 6 (14), 1739-1743 , 2020 2020 Citations: 11
Epicardial high-resolution mapping of advanced interatrial block: Relating ECG, conduction abnormalities and excitation patterns NL Ramdat Misier, MS van Schie, C Li, FBS Oei, FRN van Schaagen, ... Frontiers in Cardiovascular Medicine 9, 1031365 , 2023 2023 Citations: 10
Detection of endo-epicardial atrial low-voltage areas using unipolar and omnipolar voltage mapping MS Van Schie, P Knops, L Zhang, FRN Van Schaagen, YJHJ Taverne, ... Frontiers in Physiology 13, 1030025 , 2022 2022 Citations: 10
Conduction velocity and anisotropic properties of fibrillation waves during acutely induced and long-standing persistent AF MS van Schie, S Talib, P Knops, YJHJ Taverne, NMS de Groot Clinical Electrophysiology 10 (7_Part_2), 1592-1604 , 2024 2024 Citations: 9
