THE IMPACT OF SUPPLEMENTING BROILER CHICKENS WITH TRIBULUS TERRESTRIS POWDER ON GENE EXPRESSION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR 1 ALI A. MOHAMMED, IBTISAM N. AL-ASSAF, GHASSAN F. MOHAMMED Assiut Veterinary Medical Journal Egypt, 2025 The Tribulus terrestris plant is a key component of industrial medicinal products, because it includes a high concentration of compounds with valuable biological activity. By assessing the Growth Hormone (GH) and Insulin-Like Growth Factor 1 (IGF1) gene expression in broiler chickens, this study aimed to determine the safe dosage of T. terrestris powder that may be added to their diet. The GC-MS data demonstrated the existence of biocompounds with a variety of pharmacological properties. T. terrestris contains six fatty acids: palmitic acid, stearic acid, lauric acid, arachidonic acid, tridecylic acid, pentadecylic acid, stigmasterol, and beta-sitosterol. Following the addition of plant powder to the diet at dosages of 0.5, 1, and 1.5 gm, the GH gene expression using RT-qPCR demonstrated a noticeable rise in activity. ; The highest upregulation value determined was 3.04 folds higher than the control value (0.96) at concentrations of 1.5 gm. Additionally, the data demonstrated that the liver's IGF1 expression was upregulated at 1.5 gm, increasing 1.94 times, compared to the control's (1.06). In conclusion, the study demonstrated that adding T. terrestris to broiler chicken diets raises the expression of the GH and IGF-1 genes. It may therefore contribute to the weight gain of broiler chicks.
Essential oils and fatty acids of Thymus vulgaris seeds: chemical composition, antioxidant and antimicrobial activity Muthanna Mohammed, Ibtisam Al-assaf, Inaam Mohamad, Fawwaz Ali Egyptian Journal of Chemistry, 2023 Medicinal plants are a natural source of many existing medical products, were used widely to enhance food taste and make a fragrance, therapeutic, and preservative additive. The essential oils (E.Os) and fatty acids (F.As) are the origins of various phytochemical substances and are commercially beneficial in food and they are several biological activities including antiviral, antibacterial, anti-parasitic, and anti-inflammatory. So, the Thymus vulgaris L. seeds (Thyme) was investigated to extract E.Os and F.As and was analyzed via mass spectrometry (GC / MS) to determine their chemical composition. The results indicated that the antioxidant properties of extracting were examined using the (DPPH) free radical-scavenging method, ability of the E.Os and F.As ranged from 86.60% to 82.60 % respectively compared to the standard Quercetin (85.32 %). However, antimicrobial activity was represented against Bacillus cereus, Staphylococcus aureus, E. coli and Proteus vulgaris. Suggesting a possible link between such essential oils/fatty acids and the elimination of harmful, or potentially lethal pathogen, at least to some extent.
Protective effect of Urtica dioica in liver and kidney damages induce by ethylene glycol in rabbits: A histopathological study Muataz A. Al-Akash, Haitham A. Rajab, Ibtisam N. Al-Assaf Iraqi Journal of Veterinary Sciences, 2022 Article history: Received February 20, 2021 Accepted May 04, 2021 Available online November 22, 2021 Urtica dioica is used in the many countries as seasoning and as an herbal medicine (antioxidant). In this study, adult male locale rabbit was separated into five groups, group 1 considered as control, group 2 to 5 animals were treated with 0.75% ethylene glycol (EG) in water to induce renal and liver damage till 30 day. The group 3 to 5 animals were feed extract of the plant of U. dioica at a dosage of 100 mg/kg body weight from day 15 to the day 30. The extracts were administered twice daily orally. Liver histopathological changes characterized by vacuolar degeneration and coagulative necrosis of hepatocytes, congestion and dilatation of central vein and sinusoids. Renal histopathological changes characterized by deposition of oxalates, blood vessels congestion infiltration of inflammatory cells and change in renal glomeruli in GE treated groups. While histopathological changes in the animals group treated with U. dioica extract and ethylene glycol showed an increase improvement of the histological features of liver tissue, were limited dilatation of renal tubules with less deposition of oxalates, as well as slight infiltration of inflammatory cells in the interstitial tissue. Finally, as a conclusion we noticed that U. dioica extracts had the ameliorative effect of ethylene glycol-induced hepatic and renal histopathological.
Evaluation the sustained effect of Morus nigra leaves on growth hormones and insulin-like factor in broiler chickens IN Al-Assaf, GF Mohammed, AA Mohammed NTU Journal of Agriculture and Veterinary Science 5 (3) , 2025 2025
THE IMPACT OF SUPPLEMENTING BROILER CHICKENS WITH TRIBULUS TERRESTRIS POWDER ON GENE EXPRESSION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR 1 ALIA MOHAMMED, IN AL-ASSAF, GF MOHAMMED Assiut Veterinary Medical Journal 71 (185), 302-313 , 2025 2025 Citations: 2
Enhancing Hydroponic Strawberry Cultivation Through the Use of Alhagi maurorum Extracts as Sustainable Eco-Friendly Additives MH Yasin, IN Al-Assaf, SA Al-Bajari International Conference on Sustainable Development Techniques, 1504-1512 , 2024 2024
Exploring the therapeutic potential of bioactive compounds derived from Artemisia absinthium against breast cancer cell line. IN Al-Assaf, MJ Mohammed, FF Ali Pakistan Journal of Pharmaceutical Sciences 37 (4) , 2024 2024 Citations: 7
Essential oils and fatty acids of Thymus vulgaris seeds: chemical composition, antioxidant and antimicrobial activity IN Al-Assaf, MJ Mohammed, IJ Mohamad, FF Ali Egyptian Journal of Chemistry 66 (3), 459-464 , 2023 2023 Citations: 8
Protective effect of Urtica dioica in liver and kidney damages induce by ethylene glycol in rabbits: a histopathological study. MA Al-Akash, HA Rajab, IN Al-Assaf 2022 Citations: 9
Protective role of Urtiea dicica on the pathological alteration induced by ethylene glycol in male rabbits IN Al-Assaf, AGA Al-Dabbagh, RYQ Al-Abachi, SA Al-Bajari Sys. Rev. Pharm 11 (12), 1180-1183 , 2020 2020 Citations: 4
Protective role of Urtiea dicica on the pathological alteration induced by ethylene glycol in male rabbits INA 1, AGAAD 2, RYQAA 3, SAAB 4 Systematic Reviews in Pharmacy 11 (12), 1180-1183 , 2020 2020
Effect of Supplemental Irrigation on Vegetative Growth and Yield Properties for Two of Wheat Varieties in Erbil of Iraq SA Hassen, IN Hazim, IM Aliyas IJSPR , 2017 2017
الارتباط المظهري لتاثير عوامل مختلفة في انتاج بذور البصل ابتسام ناظم حازم و محمد علي العساف و الياس خضر هدو مجلة تكريت للعلوم الزراعية , 2014 2014
The effect of acid spray Aljprlin and add nitrogen fertilizer on two of the seeds. Alaska potatoes class MM Taha, IN Hazem, ZS Abbas, MA Assaf Diyala Agricultural Sciences Journal 5 (2) , 2013 2013
Correlation and Path Coefficient Analysis of Grain Yield and its Component of Bread Wheat (Triticum aestivum L.) MA Rashed, AT Hamodi, EN AL-Assaf 2012
دراسة المقدرة الاتحادية وقوة الهجين وتقدير معدل درجة السيادة والتوريث في حنطة الخبز (Triticum aestivum L.) ابتسام ناظم العساف JOURNAL OF EDUCATION AND SCIENCE 23 (47) , 2010 2010
تقدير قوة الهجين والفعل الجيني والتوريث في حنطة الخبز Triticum aestivamL. ابتسام ناظم حازم و محمد حامد ايوب التربية والعلم(المؤتمر العلمي الاول لعلوم الحياة) 20 (2) , 2007 2007
Genetic Analysis of Combining Ability in Bread Wheat (Triticum aestivum L.) by Diallel Crosses MH Ayoob, EN Hazim 2005
التحليل الوراثي للمقدرة الاتحادية وقوة الهجين في حنطة الخبز Triticum aestivumL. ابتسام ناظم حازم العساف كلية التربية قسم علوم الحياة , 2004 2004
MOST CITED SCHOLAR PUBLICATIONS
Protective effect of Urtica dioica in liver and kidney damages induce by ethylene glycol in rabbits: a histopathological study. MA Al-Akash, HA Rajab, IN Al-Assaf 2022 Citations: 9
Essential oils and fatty acids of Thymus vulgaris seeds: chemical composition, antioxidant and antimicrobial activity IN Al-Assaf, MJ Mohammed, IJ Mohamad, FF Ali Egyptian Journal of Chemistry 66 (3), 459-464 , 2023 2023 Citations: 8
Exploring the therapeutic potential of bioactive compounds derived from Artemisia absinthium against breast cancer cell line. IN Al-Assaf, MJ Mohammed, FF Ali Pakistan Journal of Pharmaceutical Sciences 37 (4) , 2024 2024 Citations: 7
Protective role of Urtiea dicica on the pathological alteration induced by ethylene glycol in male rabbits IN Al-Assaf, AGA Al-Dabbagh, RYQ Al-Abachi, SA Al-Bajari Sys. Rev. Pharm 11 (12), 1180-1183 , 2020 2020 Citations: 4
THE IMPACT OF SUPPLEMENTING BROILER CHICKENS WITH TRIBULUS TERRESTRIS POWDER ON GENE EXPRESSION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR 1 ALIA MOHAMMED, IN AL-ASSAF, GF MOHAMMED Assiut Veterinary Medical Journal 71 (185), 302-313 , 2025 2025 Citations: 2
Evaluation the sustained effect of Morus nigra leaves on growth hormones and insulin-like factor in broiler chickens IN Al-Assaf, GF Mohammed, AA Mohammed NTU Journal of Agriculture and Veterinary Science 5 (3) , 2025 2025
Enhancing Hydroponic Strawberry Cultivation Through the Use of Alhagi maurorum Extracts as Sustainable Eco-Friendly Additives MH Yasin, IN Al-Assaf, SA Al-Bajari International Conference on Sustainable Development Techniques, 1504-1512 , 2024 2024
Protective role of Urtiea dicica on the pathological alteration induced by ethylene glycol in male rabbits INA 1, AGAAD 2, RYQAA 3, SAAB 4 Systematic Reviews in Pharmacy 11 (12), 1180-1183 , 2020 2020
Effect of Supplemental Irrigation on Vegetative Growth and Yield Properties for Two of Wheat Varieties in Erbil of Iraq SA Hassen, IN Hazim, IM Aliyas IJSPR , 2017 2017
الارتباط المظهري لتاثير عوامل مختلفة في انتاج بذور البصل ابتسام ناظم حازم و محمد علي العساف و الياس خضر هدو مجلة تكريت للعلوم الزراعية , 2014 2014
The effect of acid spray Aljprlin and add nitrogen fertilizer on two of the seeds. Alaska potatoes class MM Taha, IN Hazem, ZS Abbas, MA Assaf Diyala Agricultural Sciences Journal 5 (2) , 2013 2013
Correlation and Path Coefficient Analysis of Grain Yield and its Component of Bread Wheat (Triticum aestivum L.) MA Rashed, AT Hamodi, EN AL-Assaf 2012
دراسة المقدرة الاتحادية وقوة الهجين وتقدير معدل درجة السيادة والتوريث في حنطة الخبز (Triticum aestivum L.) ابتسام ناظم العساف JOURNAL OF EDUCATION AND SCIENCE 23 (47) , 2010 2010
تقدير قوة الهجين والفعل الجيني والتوريث في حنطة الخبز Triticum aestivamL. ابتسام ناظم حازم و محمد حامد ايوب التربية والعلم(المؤتمر العلمي الاول لعلوم الحياة) 20 (2) , 2007 2007
Genetic Analysis of Combining Ability in Bread Wheat (Triticum aestivum L.) by Diallel Crosses MH Ayoob, EN Hazim 2005
التحليل الوراثي للمقدرة الاتحادية وقوة الهجين في حنطة الخبز Triticum aestivumL. ابتسام ناظم حازم العساف كلية التربية قسم علوم الحياة , 2004 2004
