Dr. Dattatraya Manohar Shinkar

@msgpharma.org

Associate Professor, Department of Pharmaceutics
Gokhale education Society's Sir Dr. M. S. Gosavi College of Pharmaceutical Education and Research, Nashik 422005, Maharashtra, India.

Dr. Dattatraya Manohar Shinkar


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https://researchid.co/dmshinkar

EDUCATION

Ph.D. (Pharmaceutical Sciences), M. Pharm. (Pharmaceutics)

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmaceutical Science
25

Scopus Publications

918

Scholar Citations

14

Scholar h-index

24

Scholar i10-index

Scopus Publications

  • Renewable Resources for Green Grafting: Types, Benefits, and Challenges
    Deepali D. Bhandari, Dattatraya M. Shinkar, Ramanlalal N. Kachave, Unmesh G. Bhamare, Sunil V. Amrutkar
    Green Grafting Innovations in Polymer Functionalization for Sustainable Solutions in Pharmaceutical and Healthcare Industry Part 1, 2026
    The pharmaceutical sector has been using renewable energy solutions more in recent years as part of its environmental stewardship and sustainability efforts. This development reflects an increasing understanding of the necessity of lowering carbon emissions, lessening the effects of climate change, and minimizing the environmental impact of pharmaceutical production processes. Globally, hospitals and health systems are making investments in clean, renewable energy to safeguard the health of their patients. Hospitals can continue to operate amid severe weather conditions or other disruptions by combining renewable energy with power storage. The EPA defines renewable energy as those sources that depend on non-depleting fuel sources that replenish themselves over brief periods. In reality, wind and solar energy provide the majority of renewable electricity generated in the United States since they are affordable, easily accessible, and clean. Compared to electricity, thermal energy (such as steam, heat, and hot water) presents greater challenges. Many healthcare facilities employ biomass-powered combined heat and power plants, although concerns exist regarding their impact on local health, carbon emissions, and sustainable forestry practices. Though they will need to grow in size before they can be economically utilized for healthcare, emerging technologies like green hydrogen may be useful in decarbonizing thermal energy. Green electrospinning is a promising field for sustainable nanomaterial production, offering eco-efficient methods and reducing environmental impacts. Biological nanofibers, which control drug administration and environmental cleanup, utilize strategies such as solvent removal, integration of renewable energy sources, and waste utilization. Additional investigation is required in the areas of materials engineering, scaling up procedures, achieving multifunctionality, and evaluating entire life cycle sustainability. Research on natural gums and mucilages could be used for drug delivery systems. This study examines the integration of renewable energy sources in pharmaceutical production processes, focusing on both the challenges and benefits.
  • Polymer Nanocomposite Reinforcement Strategies
    Dattatraya Manohar Shinkar, Unmesh Gulabrao Bhamare, Prakash Pannalal Muleva, Deepali Dattatray Bhandari, Ramanlal Narayan Kachave, et al.
    Polymer Nanocomposites Advances in Design Synthesis and Applications, 2026
  • Impurity profiling and forced degradation studies of angiotensin (AT1) blockers: A review
    Ramanlal N. Kachave, Deepali D. Bhandari, Prashant L. Pingale, Dattatraya M. Shinkar, Sunil V. Amrutkar
    Current Pharmaceutical Analysis, 2025
  • Formulation and Evaluation of Transdermal Patches of Clopidogrel Bisulfate
    Manisha Devram Gangurde, Dattatraya Manohar Shinkar, Sahebrao Sampat Boraste, Prashant Lakshaman Pingale, Sunil Vishvnath Amrutkar
    Research Journal of Pharmacy and Technology, 2025
    Transdermal medication delivery (TDDS) is a viable alternative to oral drug administration, offering benefits such as longer therapeutic efficacy, decreased side effects, enhanced bioavailability, improved patient compliance, and ease of drug therapy termination. A study using solvent casting method prepared nine formulations of transdermal patches using Eudragit L-100 and HPMC K4M as film forming polymers. The patches' weight, thickness, folding endurance, homogeneity of drug content, and moisture content were assessed, along with their organoleptic qualities.in-vitro release, and steady state flux. The optimized transdermal patch (F5) showed the highest drug content of 98.78%, with the highest drug release of 75.91%. The F5 batch showed the highest steady state flux of 2.922 𝝁g/cm² 12hr for clopidogrel bisulfate. The F5 batch completed three months of stability testing, showing no significant alterations to drug content, in vitro drug release, or steady state flux. The findings suggest that patches provide adequate outcomes for longer periods of time, and more clinical research is needed to establish an appropriate transdermal system for hypertension treatment.
  • Formulation, Development, and Optimization of Cefpodoxime Proxetil Nanosuspension by using 23 Factorial Design
    Rakesh Sanjay Nath, Sahebrao Sampat Boraste, Dattatraya Manohar Shinkar, Sunil Vishvanath Amrutkar, Prashant Lakshaman Pingale
    Research Journal of Pharmacy and Technology, 2025
    The two main problems with most biologically active compounds are their slow rate of breakdown and their difficulty in dissolving in water. As a member of BCS class IV, cefpodoxime proxetil has limited permeability and solubility. To increase the drug's solubility and rate of dissolution, the current study set out to create Cefpodoxime proxetil nanosuspension utilizing a solvent evaporation technique. Zeta potential, particle size, total drug content, and entrapment efficiency were assessed for the created nanosuspension formulation. Various polymers were used to create stable nanosuspension over various trial batches. Following the findings of trial batches, the polyvinylpyrrolidone k30 was selected using a 23 factorial design for the production of cefpodoxime proxetil nanosuspension. With a %Entrapment efficiency of 96.16±0.55%, batch F4 exhibited the highest percentage among the analyzed formulation batches. Among the batches, the F4 batch has the highest total drug concentration, measuring 95.61±0.32%. Every batch of nanosuspension was assessed for several characteristics; batch F4 exhibited the lowest values for the maximum zeta potential (35.4 mV), polydispersity index (0.042 ± 0.01), and particle size (160.6 ± 1.2nm), in that order. For optimization, a linear model was mostly employed. The results of the ANOVA showed that the F4 batch was the most productive. Polyvinylpyrrolidone K30 and tween 80 were used to create a stable nanosuspension that improved the solubility and subsequent release of pure Cefpodoxime proxetil medication.
  • Nutrition in skin health
    Dattatraya Shinkar, Anuradha Malode, Sahebrao Boraste, Sunil Amrutkar, Satish Rojekar
    Nutrition and Women S Health Functional Foods Nutraceuticals and Integrative Strategies, 2025
  • NATURAL ANTIOXIDANTS AS NUTRACEUTICALS
    Antioxidants as Nutraceuticals, 2025
  • Integrating multiomics data for personalized TNBC management
    Unmesh G. Bhamre, Harshal A. Kothawade, Deepali D. Bhandari, Sunil V. Amrutkar, Dattatraya M. Shinkar
    Artificial Intelligence Driven Precision Medicine for Triple Negative Breast Cancer Innovations and Insights in Tnbc Management, 2025
  • Development of In Situ Nasal Gel of Moxifloxacin HCl for Brain Targeting: Design, Optimization and In-vitro Evaluation
    Khadija Akhlaque Siddiqui, Prashant Lakshaman Pingale, Sahebrao Sampat Boraste, Sunil Vishvnath Amrutkar, Dattatraya Manohar Shinkar
    Research Journal of Pharmacy and Technology, 2025
    Bacterial meningitis is a life-threatening infection of the meninges, often caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae type b. Symptoms include high fever, headache, neck stiffness, photophobia, nausea, vomiting, and altered mental status. Diagnosis is confirmed via cerebrospinal fluid analysis, and treatment requires broad-spectrum intravenous antibiotics and corticosteroids. This study aimed to develop a thermoreversible in-situ nasal gel for Moxifloxacin HCl to enhance brain targeting and CNS absorption, reducing enzymatic breakdown and side effects. Using polymers like Xanthan gum, HPMC K4M, and Carbopol-940, the optimized gel demonstrated quick gelling, strong bioadhesion, and high ex-vivo absorption. Stability tests confirmed long-term efficacy. Further in-vivo research is needed to validate these results for meningitis treatment.
  • Future Vistas: Revolutionary Technologies and Paradigms in Stem Cell Therapeutics
    Dattatraya M. Shinkar, Sharayu P. Rathod, Priyanka D. Dabir, Sandip R. Purkar, Deepali D. Bhandari, et al.
    Stem Cell Therapeutics, 2025
  • Exploring Herbal Remedies: Traditional Wisdom Meets Modern Science
    Deepali D. Bhandari, Komal S. Hatkar, Sharayu P. Rathod, Ramanlal R. Kachave, Sunil V. Amrutkar, et al.
    Herbal Nanotherapy for Diabetes, 2025
  • Formulation, Optimization, and Evaluation of Transdermal Patches of Clotrimazole and Betamethasone Dipropionate for Candidiasis
    Research Journal of Pharmacy and Technology, 2024
  • Nanocarriers in ulcerative colitis
    Sachin Kothawade, Vishal Pande, Dattatraya Shinkar, Prashant Pingale, Sahebrao Boraste
    Nanocarrier Drug Delivery Systems Therapeutic and Diagnostic Medicine, 2024
  • Nanocarriers for treatment of parkinson's disease
    Dattatraya Shinkar, Prashant Pingale, Sahebrao Boraste, Raosaheb Ghegade, Sunil Amrutkar
    Nanocarrier Drug Delivery Systems Therapeutic and Diagnostic Medicine, 2024
  • Implication of sex differences in toxicology
    Anand More, Simranjit Kaur, Muktika Tekade, Vipulata Yeole, Prashant L. Pingale, et al.
    Public Health and Toxicology Issues in Drug Research Volume 2 Toxicity and Toxicodynamics, 2024
  • Advancement and Authentication of Spectrophotometric Method for Detection of Losartan Potassium
    Y. S. Chavan, D. M. Shinkar, S. S. Jadhav, S. S. Boraste, P. L. Pingale, et al.
    Chemistry Africa, 2022
  • Formulation, Evaluation and Characterization of Mouth Dissolving Film of Cisapride
    Current Trends in Biotechnology and Pharmacy, 2022
  • Case study: Indian herbal bioenhancers
    Dattatraya M. Shinkar, Sunil V. Amrutkar, Prashant L. Pingale
    Drug Delivery Technology Herbal Bioenhancers in Pharmaceuticals, 2022
  • Solubility and dissolution enhancement of sulfasalazine by solid dispersion technique
    D. M. Shinkar, A. N. Patil, R. B. Saudagar
    Research Journal of Pharmacy and Technology, 2018
  • An review on floating mucoadhesive drug delivery system
    M.S. Alai, D.M. Shinkar, R.B. Saudagar
    Research Journal of Pharmacy and Technology, 2017
  • Solubility and dissolution enhancement of carvedilol by solid dispersion technique using gelucire 50/13
    International Journal of Pharmaceutical Sciences Review and Research, 2014
  • Development and evaluation of in situ nasal mucoadhesive gel of metoprolol succinate by using 32 full factorial design
    International Journal of Pharmacy and Pharmaceutical Sciences, 2014
  • Topical gel: A novel approach for development of topical drug delivery system
    International Journal of Pharmacy and Technology, 2013
  • Drug delivery from the oral cavity: A focus on mucoadhesive buccal drug delivery systems
    D. M. Shinkar, A. S. Dhake, C. M. Setty
    PDA Journal of Pharmaceutical Science and Technology, 2012
  • Development and evaluation of mucoadhesive tablets of clotrimazole and its βcyclodextrin complex for the treatment of candidiasis
    International Journal of Pharmacy and Pharmaceutical Sciences, 2011

RECENT SCHOLAR PUBLICATIONS

  • Renewable Resources for Green Grafting: Types, Benefits, and Challenges
    DD Bhandari, DM Shinkar, RN Kachave, UG Bhamare, SV Amrutkar
    Green Grafting: Innovations in Polymer Functionalization for Sustainable … , 2026
    2026
  • Polymer Nanocomposite Reinforcement Strategies
    DM Shinkar, UG Bhamare, PP Muleva, DD Bhandari, RN Kachave, ...
    Polymer Nanocomposites: Advances in Design, Synthesis, and Applications, 161-176 , 2026
    2026
  • Nutrition in skin health
    D Shinkar, A Malode, S Boraste, S Amrutkar, S Rojekar
    Nutrition and Women's Health, 275-287 , 2026
    2026
  • Integrating multiomics data for personalized TNBC management
    UG Bhamre, HA Kothawade, DD Bhandari, SV Amrutkar, DM Shinkar
    Artificial Intelligence-Driven Precision Medicine for Triple Negative Breast … , 2026
    2026
  • Formulation and Evaluation of Transdermal Patches of Clopidogrel Bisulfate
    SVA Manisha Devram Gangurde, Dattatraya Manohar Shinkar, Sahebrao Sampat ...
    Research Journal of Pharmacy and Technology 18 (12), 07 , 2025
    2025
  • Exploring Herbal Remedies: Traditional Wisdom Meets Modern Science
    DD Bhandari, KS Hatkar, SP Rathod, RR Kachave, SV Amrutkar, ...
    Herbal Nanotherapy for Diabetes, 52-83 , 2025
    2025
    Citations: 1
  • Development of In Situ Nasal Gel of Moxifloxacin HCl for Brain Targeting: Design, Optimization and In-vitro Evaluation
    KA Siddiqui, PL Pingale, SS Boraste, SV Amrutkar, DM Shinkar
    Research Journal of Pharmacy and Technology 18 (10), 5003-5010 , 2025
    2025
  • Future Vistas: Revolutionary Technologies and Paradigms in Stem Cell Therapeutics
    DM Shinkar, SP Rathod, PD Dabir, SR Purkar, DD Bhandari, SV Amrutkar
    Stem Cell Therapeutics, 107-158 , 2025
    2025
  • Formulation, Development, and Optimization of Cefpodoxime Proxetil Nanosuspension by using 23 Factorial Design
    RS Nath, SS Boraste, DM Shinkar, SV Amrutkar, PL Pingale
    Research Journal of Pharmacy and Technology 18 (6), 2774-2779 , 2025
    2025
  • Impurity profiling and forced degradation studies of angiotensin (AT1) blockers: A review
    RN Kachave, DD Bhandari, PL Pingale, DM Shinkar, SV Amrutkar
    Current Pharmaceutical Analysis 21 (3), 128-144 , 2025
    2025
    Citations: 5
  • Natural Antioxidants as Nutraceuticals
    DM Shinkar, AB Page, PS Malpure, B Rane, PL Pingale
    Antioxidants as Nutraceuticals, 3-37 , 2025
    2025
  • Nanocarriers for treatment of Parkinson’s disease
    D Shinkar, P Pingale, S Boraste, R Ghegade, S Amrutkar
    2024
  • Formulation, Optimization, and Evaluation of Transdermal Patches of Clotrimazole and Betamethasone Dipropionate for Candidiasis
    SVA Shivani A Wable, Prashant L Pingale, Dattatray M Shinkar, Sahebrao S Boraste
    Research Journal of Pharmacy and Technology 17 (9), 4267-4274 , 2024
    2024
    Citations: 1
  • Nanocarriers in ulcerative colitis
    BS Kothawade Sachin, Pande Vishal, Shinkar Dattatraya, Pingale Prashant
    Nanocarrier Drug Delivery Systems: Therapeutic and Diagnostic Medicine … , 2024
    2024
  • Implication of sex differences in toxicology
    A More, S Kaur, M Tekade, V Yeole, PL Pingale, D Shinkar, RK Tekade
    Public Health and Toxicology Issues in Drug Research, 121-142 , 2024
    2024
    Citations: 3
  • Formulation, optimization, and evaluation of herbal mouth freshener chewable tablets
    HPS Sakshi P. Wani, Prashant L. Pingale, Dattatraya M. Shinkar, Sahebrao S ...
    Advances in Bioresearch 14 (6), 9 , 2023
    2023
  • Recent Advances in Nanoparticles in Diagnosis and Treatment of Neurodegenerative Disorders
    SVA Ashiti M. Ghule, Prashant L. Pingale, Rupali A. Patil, Dattatraya M ...
    Advances in Bioresearch 14 (6), 13 , 2023
    2023
  • Current Avenues in Nanotechnology-based Drug Delivery System for Brain Targeting
    SA Neha Ahire, Prashant Pingale, Dattatraya Shinkar, Sahebrao Boraste
    Advances in Bioresearch 14 (6), 10 , 2023
    2023
  • MICROSPONGES: AN EMERGING FORMULATION TOOL FOR TOPICAL DRUG DELIVERY
    SVA Sakshi Pravin Wani, Dattatraya Manohar Shinkar, Prashant Laxman Pingale ...
    Pharmacophore an International Research Journal 13 (6), 20-34 , 2022
    2022
    Citations: 5
  • Advancement and authentication of spectrophotometric method for detection of losartan potassium
    YS Chavan, DM Shinkar, SS Jadhav, SS Boraste, PL Pingale, ...
    Chemistry Africa 5 (6), 2061-2066 , 2022
    2022
    Citations: 3

MOST CITED SCHOLAR PUBLICATIONS

  • Drug delivery from the oral cavity: A focus on mucoadhesive
    DM Shinkar, AS Dhake, CM Setty
    PDA J. Pharm. Sci. Technol 66, 466-500 , 2012
    2012
    Citations: 155
  • A review on intranasal drug delivery system
    PS Appasaheb, SD Manohar, SR Bhanudas, N Anjaneri
    Journal of Advanced Pharmacy Education & Research 3 (4) , 2013
    2013
    Citations: 114
  • Review on solubility enhancement techniques
    SV Kadam, DM Shinkar, RB Saudagar
    IJPBS 3 (3), 462-75 , 2013
    2013
    Citations: 71
  • Pharmaceutical cocrystallization: a review
    AN Sanjay, D Manohar, SR Bhanudas
    J Adv Pharm Educ Res 4 (4), 388-96 , 2014
    2014
    Citations: 46
  • Topical gel: A novel approach for development of topical drug delivery system
    SJ Shelke, DM Shinkar, RB Saudagar
    Int J Pharm Technol 5 (3), 2739-2763 , 2013
    2013
    Citations: 42
  • Review article: solubility Enhancement by solid dispersion
    AN Patil, DM Shinkar, RB Saudagar
    Int J Curr Pharm Res 9 (3), 15-18 , 2017
    2017
    Citations: 31
  • Ethosomes: carrier for enhanced transdermal drug delivery system
    GA Ramakrishna, SD Manohar, SR Bhanudas
    J. Adv. Pharm. Educ. Res 4, 380-387 , 2014
    2014
    Citations: 30
  • Mucoadhesive buccal drug delivery: An Overview
    GS Shridhar, SD Manohar, SR Bhanudas, N Anjaneri
    Journal of Advanced Pharmacy Education and Research 3 (4), 319-332 , 2013
    2013
    Citations: 30
  • Moringa oleifera as a pharmaceutical excipient
    B Uphadek, DM Shinkar, PB Patil, RB Saudagar
    Int J Curr Pharm Res 10 (2), 13-16 , 2018
    2018
    Citations: 21
  • Development of UV Spectrophotometric Method for Estimation of carvedilol in bulk and Pharmaceutical Formulations
    SCM Shinkar D.M., Dhake A.S.
    Asian Journal of Research in Chemistry 6 (10), 4 , 2013
    2013
    Citations: 21
  • Development and Evaluation of In Situ Nasal Mucoadhesive Gel of Metoprolol Succinate By Using 32 full Factorial Design
    SRB Pagar S. A., Shinkar D.M.
    IJPPS 6 (11), 7 , 2014
    2014
    Citations: 19
  • FORMULATION AND IN VITRO EVALUATION OF FAST DISSOLVING TABLET OF VERAPAMIL HYDROCHLORIDE
    ADM DATTATRAYA M. SHINKAR, POOJA S. AHER, PARAG D. KOTHAWADE
    International Journal of Pharmacy and Pharmaceutical Sciences 10 (10), 93-99 , 2018
    2018
    Citations: 17
  • Hydrogel-a novel technique for prepartion of topical gel
    TA Ganesh, SD Manohar, SR Bhanudas
    World J. Pharm. Pharm. Sci 2 (6), 4520-4541 , 2013
    2013
    Citations: 14
  • Development and validation of spectrophotometric method for determination of metoprolol succinate
    SA Pagar, DM Shinkar, RB Saudagar
    International journal of pharmacy and biological sciences 3, 224-228 , 2013
    2013
    Citations: 14
  • Microsponges
    DM Shinkar, BS Bhamare, RB Saudagar
    Asian Journal of Research in Pharmaceutical Science 6 (2) , 2016
    2016
    Citations: 13
  • Chemical penetration enhancers—a review
    SS Jagannath, SD Manohar, SR Bhanudas
    World Journal of Pharmacy and Pharamceutical Sciences 3 (2), 1068-80 , 2013
    2013
    Citations: 13
  • Hydrogel-a novel technique for preparation of topical gel
    AG Tahsildar, DM Shinkar, RB Saudagar
    World Journal of Pharmacy and Pharmaceutical Sciences 2 (6), 4520-4541 , 2013
    2013
    Citations: 13
  • Development and evaluation of mucoadhesive tablets of clotrimazole and its β-cyclodextrin complex for the treatment of candidiasis
    AS Dhake, DM Shinkar, S Shayle, SB Patil, CM Setty
    Int. J. Pharm. Pharm. Sci 3 (3), 159-164 , 2011
    2011
    Citations: 13
  • Formulation, evaluation, and optimization of glimepiride nanosuspension by using antisolvent evaporation technique
    DM Shinkar, SS Jadhav, PL Pingale, SS Boraste, S VishvnathAmrutkar
    Pharmacophore 13 (4-2022), 49-58 , 2022
    2022
    Citations: 11
  • Solubility and dissolution enhancement of sulfasalazine by solid dispersion technique
    DM Shinkar, AN Patil, RB Saudagar
    Research Journal of Pharmacy and Technology 11 (4), 1277-1282 , 2018
    2018
    Citations: 11