M. Sc., M. Phil., & Ph. D degrees from Gulbrga University, Gulbarga. Presently working as s assistant Professor and PG coordinator, Dept. of PG studies in Chemistry, kuvempu University, Sahyadri Science College, SHIVAMOGGA, karnataka, india
EDUCATION
M. Sc., M. Phil., Ph. D.
RESEARCH, TEACHING, or OTHER INTERESTS
Multidisciplinary, General Chemistry, Organic Chemistry, Spectroscopy
18
Scopus Publications
Scopus Publications
Design of an efficient three component one-pot synthesis of -1,2,3,4-tetrahydro-4-oxo-6-(5-substituted 2-phenyl-1H-indol-3-yl)-2-thioxopyrimidine-5-carbonitrile as antimicrobial and antitubercular agent Indian Journal of Chemistry Ijc, 2022 In the present study, a novel, rapid, improved and eco-friendly synthesis of indolyl-pyrazolo-pyrimidine derivatives 4a-c by using conventional method via one-pot multi-component reaction has been described. The structures of all these unknown compounds have been confirmed with the help of physical and spectroscopic techniques like IR, 1 H and 13 C NMR and mass spectrometry and these newly synthesized compounds have been evaluated for in vitro antimicrobial and antitubercular and antioxidant activities. The results reveal that compound 4a exhibits promising antimicrobial, antitubercular and antioxidant properties when compared to the standard drugs.
Synthesis, optical, photocatalytic and electrochemical properties of cobalt doped ZnS nanoparticles K.R. Sumadevi, G. Krishnamurthy, H.S. Bhojya Naik, Prabhaker Walmik, Malathesh Pari, N. Ranjitha, R.S. Priya Rani, P. Parameshwara Naik Asian Journal of Chemistry, 2021 Poly(vinyl pyrrolidone) capped and uncapped Co:ZnS nanoparticles have been synthesized by co-precipitation method. These synthesized nanoparticles were characterized using spectral techniques and the optical and photoluminescence properties of nanoparticles were also studied. Poly(vinyl pyrrolidone) capped nanoparticles has been studied for the electrochemical sensing of various biomolecules. The Co:ZnS modified glassy carbon electrode (GCE) proved to be effective nanoparticles composite electrode to detect biomolecules electrochemically with a wide linear detection range of 0.2 to 1.6 μmol/L, Also a low detection limit (LOD) of 0.06 μM/L and excellent sensitivity of 4.366 μA μM-1 has been obtained. It is observed that the particle size of nanoparticles is affected by the capping agent. It is therefore the modified electrode has become a good electrode material with a greater stability without leaching. The optical band gap was determined by UV-visible spectra and the value is found to be in the range of 3.75 to 4.00 eV. The photocatlytic activity on Eriochrome black T dye in the visible region using nanoparticles has been determined. It was found that the capped nanoparticles are more effective in photocatalytic degradation due to low energy consumption and safe recovery of it after catalytic performance from polluted water.
Synthesis and biological evaluation of novel indolyl-dihydropyridin-3-carboxylate, dihydro[1,2,4]triazol[1,5]pyridin-3-carboxylate and carbohydrazide derivatives Indian Journal of Chemistry Section B Organic and Medicinal Chemistry, 2020
Design, synthesis of biologically active heterocycles containing Indol- Thiazolyl- Thiazolidinone derivatives Prabhakar Walmik, Basavaraj S Naraboli, Swathi B, Somashekhar Ghanti Asian Journal of Pharmaceutical and Clinical Research, 2018 Objective: The present study envisage a novel series of thiazole, indole and thiazolidine derivatives, namely, N-((5-Substituted-2-phenyl-1 H-indol-3-yl)methylene)-4,5,6,7-tetrahydro-5,7,-dimethylbenzo [d]thiazole-2-amine (4a-c), 2-(5-substituted-2-phenyl-1H-indol-3-yl)-3-(4,5,6,7- trimethylbenzo[d]thiazol-2-yl)-thiazolidin-4-one (5a-c) and 5-benzylidine-2-(5-substituted-2phenyl-1H-indol-3yl)-3-(4,5,6,7-tetrahydro-5,5,7- trimethylbenzo[d]thiazol-2-yl) thiazolidin-4-one (6a-c).Methods: All the newly synthesized compounds were characterized by infrared, 1H, 13C nuclear magnetic resonance and mass spectral data and elemental analysis and evaluated for in vitro antimicrobial activity.Results: Novel compounds N-((5-Substituted-2-phenyl-1H-indol-3-yl)methylene)-4,5,6,7-tetrahydro-5,7,-dimethylbenzo [d]thiazole-2-amine (4a-c), 2-(5-substituted-2-phenyl-1H-indol-3-yl)-3-(4,5,6,7-trimethylbenzo[d]thiazol-2-yl)-thiazolidin-4-one (5a-c) and 5-benzylidine-2-(5-substituted- 2phenyl-1H-indol-3yl)-3-(4,5,6,7-tetrahydro-5,5,7-trimethyl benzo[d]thiazol-2-yl)thiazolidin-4-one (6a-c) have been made and characterized using spectral and analytical data. The results of antibacterial and antifungal activities showed that some of the synthesized compounds exhibited promising activities.Conclusion: All the newly synthesized compounds were carried out by the broth microdilution method (NCCLS. 2002) in a DMF concentration of 500, 250, 125, and 62.5 μg/ml. Gentamycin and fluconazole are used as reference standards for antibacterial and antifungal activity, respectively. The final results revealed that compounds 4b, 5b, and 6b exhibited potent antimicrobial activity when compared to the standard drugs.
Synthesis of novel indolyl-thiazolidinone derivatives as antioxidant, antimicrobial and atitubercular agents Der Pharma Chemica, 2015
Synthesis of novel indolyl-azetidinone and thiazolidinone derivatives as a potent antioxidant, antimicrobial and antitubercular agents Der Pharma Chemica, 2014
Synthesis of novel N-(aryl) diazenyl thiazol-2-amines and bezylidenethiazolidin- 4-ones linked to indole nucleus as antioxidant, antimicrobial, antimycobacterial and cytotoxic agents International Journal of Pharmacy and Pharmaceutical Sciences, 2014
Synthesis, antioxidant and antimicrobial activities of indolyl pyrazoles Indian Journal of Heterocyclic Chemistry, 2012
Synthesis, antimicrobial and antioxidant activities of some indole analogues containing naphthyridine and pyrimidonaphthyridine systems Indian Journal of Chemistry Section B Organic and Medicinal Chemistry, 2012
Synthesis and biological activities of some 5-substituted 2-phenyl-3-(6-aryl-3-cyano-2-substituted pyridin-4-yl) indoles Indian Journal of Heterocyclic Chemistry, 2011
Synthesis and antimicrobial activities of 5(2' S'-disubstitutedih- Indol-3'-yl)-5h-thiazolo [4,3-b]1,3,4-oxadiazole, -1,3,4-thiadiazole, -1,2,4triazole and their derivatives Heterocyclic Communications, 2009