Somova Aleksandra

@spbu.ru

Department of General Surgery
Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University"

Somova Aleksandra


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https://researchid.co/aleksandrasomova

EDUCATION

Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia

RESEARCH, TEACHING, or OTHER INTERESTS

Surgery, Endocrinology
4

Scopus Publications

Scopus Publications

  • Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study
    Fabio Medas, Chiara Dobrinja, Ebtesam Abdullah Al-Suhaimi, Julia Altmeier, Said Anajar, Akif Enes Arikan, Irina Azaryan, Lovenish Bains, Giancarlo Basili, Hakan Bolukbasi, Marco Bononi, Farzad Borumandi, Mehmet Buğra Bozan, Gabriela Brenta, Laurent Brunaud, Maximilian Brunner, Antoine Buemi, Gian Luigi Canu, Federico Cappellacci, Sara Burchfield Cartwright, Ignasi Castells Fusté, Beatriz Cavalheiro, Giuseppe Cavallaro, Andres Chala, Shun Yan Bryant Chan, John Chaplin, Mustafa Sajjad Cheema, Costanza Chiapponi, Maria Grazia Chiofalo, Emmanuel Chrysos, Annamaria D'Amore, Michael de Cillia, Carmela De Crea, Nicolò de Manzini, Leandro Luongo de Matos, Loredana De Pasquale, Paolo Del Rio, Marco Stefano Demarchi, Muthuswamy Dhiwakar, Gianluca Donatini, Jose Miguel Dora, Valerio D'Orazi, Viyey Kishore Doulatram Gamgaram, Vitalijus Eismontas, El Hassane Kabiri, Hadj Omar El Malki, Islam Elzahaby, Octavian Enciu, Antoine Eskander, Francesco Feroci, David Figueroa-Bohorquez, Dimitrios Filis, François Gorostidi, Pedro Frías-Fernández, Armando Gamboa-Dominguez, Volkan Genc, Davide Giordano, Antonio Gómez-Pedraza, Giuseppa Graceffa, James Griffin, Sofia Cuco Guerreiro, Karan Gupta, Keshav Kumar Gupta, Angela Gurrado, Jiannis Hajiioannou, Tommi Hakala, Wirsma Arif Harahap, Lindsay Hargitai, Dana Hartl, Andrzej Hellmann, Jiri Hlozek, Van Trung Hoang, Maurizio Iacobone, Nadia Innaro, Orestis Ioannidis, J H Isabelle Jang, Jose Candido Xavier-Junior, Milan Jovanovic, Reto Martin Kaderli, Fahmi Kakamad, Krzysztof Kaliszewski, Martin Karamanliev, Hiroshi Katoh, Andro Košec, Bozidar Kovacevic, Luiz Paulo Kowalski, Robert Králik, Sanjay Kumar Yadav, Adriána Kumorová, Savvas Lampridis, Konstantinos Lasithiotakis, Jean-Christophe Leclere, Eugene Kwong Fei Leong, Melvin Khee-Shing Leow, James Y Lim, Leonardo S Lino-Silva, Shirley Yuk Wah Liu, Núria Perucho Llorach, Celestino Pio Lombardi, Javier López-Gómez, Eleonora Lori, Lourdes Quintanilla-Dieck, Roberta Lucchini, Amin Madani, Dimitrios Manatakis, Ivan Markovic, Gabriele Materazzi, Haggi Mazeh, Giuseppe Mercante, Goswin Yason Meyer-Rochow, Olgica Mihaljevic, Julie A Miller, Michele Minuto, Massimo Monacelli, Francesk Mulita, Barbara Mullineris, José Luis Muñoz-de-Nova, Fábio Muradás Girardi, Saki Nader, Tangjaturonrasme Napadon, Constantinos Nastos, Chiara Offi, Ohad Ronen, Luigi Oragano, Aida Orois, Yongqin Pan, Emmanouil Panagiotidis, Ramakanth Bhargav Panchangam, Theodosios Papavramidis, Pradipta Kumar Parida, Anna Paspala, Òscar Vidal Pérez, Sabrina Petrovic, Marco Raffaelli, Constanza Fernanda Ramacciotti, Tomas Ratia Gimenez, Ángel Rivo Vázquez, Jong-Lyel Roh, Leonardo Rossi, Alvaro Sanabria, Alena Santeerapharp, Arseny Semenov, Sanjeewa Seneviratne, Altinay Serdar, Patrick Sheahan, Sean C Sheppard, Rachel L Slotcavage, Constantin Smaxwil, Soo Young Kim, Salvatore Sorrenti, Eleftherios Spartalis, Chutintorn Sriphrapradang, Mario Testini, Yigit Turk, George Tzikos, Kristina Vabalayte, Kelly Vargas-Osorio, Rafael Sebastián Vázquez Rentería, David Velázquez-Fernández, Sanura Malinda Pallegoda Vithana, Levent Yücel, Erwin Danil Yulian, Petra Zahradnikova, Paul Zarogoulidis, Evgeniia Ziablitskaia, Anna Zolotoukho, Pietro Giorgio Calò, A Abdallah, AL Abentroth, V Acheimastos, M Agunaoun, HM Al Bisher, A Al Ghuzlan, H Alakus, M Alkan, MC Almaraz Almaraz, K Amram, S Anesidis, E Anestiadou, D Angelucci, GL Ansaldo, MI Antonopoulou, M Arciniegas, C Armellin, G Arredondo Saldaña, J Astl, E Athanasakis, S Avenia, H Aydın, B Baba, J Babala, MV Banús, LA Barba-Valadez, SV Barcons, F Battafarano, A Bayat, RMC Bella, F Benariba, S Bernardi, EG Bignami, M Bitenc, S Bitsianis, JDD Bolaños de la Torre, E Bonati, T Bonetti, FA Borges, K Bouchagier, M Boudina, A Bourial, I Breuskin, P Brock, C Bruns, MC Burlacu, T Burton, M Buta, D Buzanakov, C Caliseo, D Callanan, V Calu, JM Cameselle-Teijeiro, DJ Camilo-Junior, S Canberk, V Candalise, F Candanedo-Gonzalez, LJ Carrillo Lizarazo, GB Carvalho, D Casallas, C Casolino, L Castellani, C Castillo Morales, G Chambon, V Chatzipavlidou, R Chernikov, A Chorti, TCM Chow, A Chrisoulidou, E Chrysos, S Conrado-Neto, D Cordova García, A Corigliano, A Crocco, A Cuesta, M Čukman, LS Curto, RA Damilano, R D'Anna, M De, A De Virgilio, D Dellaportas, L Demarquet, A Devresse, G Di Meo, R Diaz Pedrero, D Dimitrov, Z Dmitry, P Domínguez Garijo, O Dulgeroglu, AC Dural, A Eksi, M El Hammoumi, H El Kaoui, G Eleni, A Elliyanti, Ş Ersöz, M Escobar-Jiménez, L Fedorova, L Feeley, E Fernández Rodríguez, F Ferreli, A Filoia, A Fingeret, A Francescato, F Gaino, F Galiandro, JF Gallegos-Hernández, G Garas, F García Lorenzo, JP García-Chávez, M Gaudiello, S Gay, S Gerasimos, M Gerek, R Gervasi, A Giordano, B Gjeloshi, L Gocký, E Golubinskaya, S González Romero, C González-Mínguez, M Goran, A Gosman, M Granados Garcia, E Greco, M Grünbart, R Grützmann, J Guerlain, XG Guirao, D Guzey, A Hajjij, O Hamdy, MS Hameed, LA Hauth, JD Hernández-Acevedo, JF Hernandez-Carrillo, F Hevilla Sánchez, H Hoi, K Hongkwon, R Hu Zhu, E Huang, K Hyeung Kyoo, V Ignjatovic, A Ioannidis, A Iossa, A Işık, D James, L Jung Hoon, H Kara, J Karajovic, D Kartini, D Khambri, I Kholová, M Kisiel, M Knežević, YQ Koh, C Konca, C Kosmidis, G Kotsovolis, LP Kowalski, R Kralik, P Kuczma, BG Kuravi, A Kurnia, V Kyriaki, CM Lai, B Lallemant, AA Lardhi, S Leboulleux, JW Lee, G Lelli, M Leutner, MY Lim, CM Lim, A Llanos, X Lo, T Loderer, MA López-Corrales, M Ludwig, FF Magnabosco, C Maheo, AL Maia, O Makay, P Maksimova, S Mallick, C Mallouk, Z Mamani, S Mandal, M Manyalich Blasi, G Marincola, M Marulanda, M Mavromati, S Mayilvaganan, S Metso, A Micalizzi, A Michalopoulos, K Min-Su, A Miron, AK Mishra, C Misso, C Mittermair, Y Morosán Allo, M Mourad, M Moysidis, F Nabhan, R Nasiri, C Nastos, KY Ngiam, C Nomine-Criqui, AM Ntziovara, JM Nuño Vázquez-Garza, V Nutautiene, K Obtulovičová, L O'Keeffe, NO Okudur, P Ossola, E Ovejero Merino, M Ozdemir, A Pangonis, SS Panigoro, A Panuzi, D Papaconstantinou, N Pardo Matamoros, S Paschou, A Pasculli, K Paterakis, K Peiris, F Pennestrì, M Peppa, P Perdikaris, I Perdikaris, RH Pérez-Soto, S Piana, M Piccoli, D Pietrasanta, G Placentino, I Pliakos, A Polistena, A Pongtippan, G Potard, V Quinn, P Rahul, T Ramos, A Rankin, P Ratnayake, J Reuto-Castillo, A Ridolfo, J Rios-Valencia, P Riss, E Rival, J Rivillas, D Roi, EM Rollo, A Romanchishen, M Romito, J Rotnagl, B Rovcanin, G Russo, M Sabol, S Saki, S Saleh, A Salih, A Saltiki, G Salvador-Camarmo, DK Samal, S Sánchez-Flores, K Sapalidis, D Sarin, H Sarin, N Savkovic, RS Scheffel, AL Scheinpflug, C Scheuba, N Scheyer, M Schmidt, O Senashova, E Serafini, ML Serrano Arévalo, J Shank, ML Shindo, M Shoshkova, M Shvan, M Sičák, TG Silva, O Simó Guerrero, V Skuletic, N Slijepcevic, Z Slovic, P Soares, A Somova, S Soto, S Spiezia, V Stankovic, KJ Stephenson, E Straub, M Summa, S Surani, AA Syed, S Symeonidis, A Taciak, M Tarallo, A Tarle, N Tasis, K Tausanovic, L Tchabashvili, M Thierry, U Tokarczyk, EA Toma, S Topuz, F Torresan, C Uras, C Vaccaro, Á Valdés de Anca, M Valentini, E Varaldo, JG Vartanian, GI Verras, A Vithanage, H Wijayalathge, P Wiriyaamornchai, YLC Wong, P Wongwattana, S Xenaki, S Xie, M Xu, W Yang, S Yilmaz, YF Yılmaz, T Yotsov, MT Zahid, A Zielke
    Lancet Diabetes and Endocrinology, 2023
  • Intraoperative prevention of postoperative hypoparathyroidism
    Kristina Vabalayte, Anatoly Romanchishen, Aleksandra Somova
    Frontiers in Endocrinology, 2023
    ObjectiveMore than 30,000 thyroid surgeries are performed annually in the Russian Federation. The surgeries are relatively safe because of the prevention methods for postoperative complications. Currently, there is no single effective method of postoperative hypoparathyroidism prevention. This complication is frequently reported and may be health and life-threatening.AimWe aimed to estimate the effectiveness of the intraoperative ICG-angiography and intrathyroid injection of Brilliant Green for the prevention of postoperative hypoparathyroidism.Material and methodsOne hundred and forty-three thyroidectomies were performed. Patients were divided into three groups: intraoperative angiography was used in 24 cases; Brilliant Green was injected in 58 cases to identify parathyroid glands; the visual estimation of the parathyroid preservation was used in 61 cases. Calcium level was measured in all patients before and after surgery.ResultsCalcium level in the serum before and after surgery was 2.37±0.14 and 2.27±0.17 in Group 1, 2.38±0.16 and 2.21±0.16 in Group 2, and 2.39±0.17 and 2.18±0.19 in Group 3. Postoperative hypocalcemia was more prominent in the group with the visually estimated PTG than in the two other groups. The differences in postoperative calcium levels in Groups 1 and 3 were statistically different. Pre- and postoperative Parathormone levels were 6.2±0.4 in Group 1, 5.6±0.57 in Group 2, and 3.5±0.32 in Group 3. Postoperative levels significantly differed in Groups 1 and 3 (p<0.01) and in Groups 2 and 3 (p<0.05).ConclusionsICG-angiography and intrathyroid injection of the Brilliant Green are safe methods of identification and sparing of the parathyroid glands. The severity of hypocalcemia and hypoparathormonemia in Group 3 shows the necessity of finding new methods in endocrine surgery to improve patient outcomes.
  • The Role of Carotid Body in the Vital Signs’ Changes after Thyroid Surgery: An Experimental Study
    Kristina Vabalayte, Romanchishen Af, Eugenii Tymkiv, Alexandra Somova
    Head and Neck Russian Journal, 2023
    Aim: to investigate the underlying causes of altered vital signs in an animal model of post-thyroidectomy bleeding. Material and methods. We performed a series of in vivo animal studies simulating post-thyroidectomy hemorrhage and its effect on respiratory and cardiovascular system. Two series of tests were carried out in 20 Chinchilla rabbits under general anesthesia. The rabbits were intubated. The first experimental series involved 10 animals. Postthyroidectomy hemorrhage in this series was simulated by injections of autologous blood (5.0–10.0 ml) under the fascia of cervical neurovascular bundles. The pressure induced by post-thyroidectomy hemorrhage in the second series was simulated by mechanical compressions of the carotid body unilaterally or bilaterally. The minimum compression time reached 1 minute. The maximum compression time was 20 minutes. Blood pressure, heart rate, and respiratory rate were measured in all cases. Results. Mechanical compression of the carotid body resulted in decreased blood pressure, respiratory and heart rate values. Time to complete recovery of respiratory and cardiovascular function depended on the duration of compression. Conclusion. Respiratory and cardiovascular function can be suppressed by compression of the carotid body. Post-thyroidectomy hematomas must be evacuated immediately. Цель исследования: выяснить основные причины расстройств жизненно важных функций у больных кровотечениями в ложе щитовидной железы (ЩЖ) в послеоперационном периоде в эксперименте. Материал и методы. Исследование выполнено на 20 кроликах породы шиншилла. Выполняли моделирование послеоперационной гематомы и оценивали влияние гематомы на дыхательную и сердечно-сосудистую системы. Вмешательства на животных проводили под общей анестезией, все кролики были интубированы. Животные были разделены на 2 группы в зависимости от способа моделирования гематомы. 1-я группа – 10 особей, которым вводили собственную кровь (5,0–10,0 мл) под фасцию сосудисто-нервного пучка, 2-я группа – 10 особей, которым компрессионное воздействие послеоперационной гематомы осуществлялось с помощью наложения зажима на область сонного гломуса с одной и двух сторон. Минимальное время компрессии – 1 минута, максимальное – 20 минут. Оценивали частоту сердечных сокращений, артериальное давление и частоту дыхательных движений во всех наблюдениях. Результаты. Механическое сдавление сонного гломуса приводило к снижению АД, уменьшению частоты сердечных сокращения и дыхательных движений. Время восстановления жизненных функций зависело от длительности компрессии. Заключение. Сдавление синокаротидной рефлексогенной зоны приводит к нарушению витальных функций. Эвакуация гематомы из ложа удаленной ЩЖ должна выполняться незамедлительно.
  • The use of fluorescent angiography with indocyanine green in endocrine surgery - a future technology for identification of the parathyroid glands or a fleeting hobby?
    К.В. Вабалайте, А.Д. Сомова, А.Ф. Романчишен
    Head and Neck Russian Journal, 2020
    Рост числа пациентов, страдающих заболеваниями щитовидной железы (ЩЖ), неизбежно приводит к увеличению числа хирургических вмешательств на данном органе. Проблема возникновения послеоперационного гипопаратиреоза (ГПТ) в настоящее время продолжает быть актуальной, несмотря на различные методы идентификации околощитовидных желез (ОЩЖ). В последние годы в различных областях хирургии успешно применяется флуоресцентная ангиография с индоцианином зеленым, позволяющая надежно оценить степень перфузии различных органов и тканей. В настоящей статье рассматривается международный опыт использования вышеуказанной методики в эндокринной хирургии в качестве метода профилактики послеоперационного ГПТ в зависимости от активности интраоперационного кровоснабжения ОЩЖ. Показано, что использование флуоресцентной ангиографии с индоцианином зеленым является надежным методом для идентификации и сохранения ОЩЖ. Таким образом, данная технология может позволить свести к минимуму риск послеоперационного ГПТ. An increase in the number of patients with thyroid gland diseases leads to an increase of cases when thyroid surgery is indicated. Despite of the existence of various methods for identifying the parathyroid glands, the issue of postoperative hypoparathyroidism is relevant until nowadays. Recently ICG fluorescent angiography has been successfully introduced into various fields of surgery. It provides reliable assessment of perfusion in various organs and tissues. This article addresses the international experience in ICG fluorescent angiography in endocrine surgery for postoperative hypoparathyroidism prevention, depending on intraoperative blood flow activity in the parathyroid glands. It is shown that ICG fluorescent angiography is a reliable method of the parathyroid glands identification and preservation. This technology may thereby minimize the risk of postoperative hypoparathyroidism.