Laura Fugazzola

Scopus Publications

How genetics changed or will change the therapy in thyroid nodules with indeterminate cytology?
Marina Muzza, Carla Colombo, Laura Fugazzola, Luca Persani
Annales D Endocrinologie, 2026
The incidence of thyroid cancer has risen in recent decades, largely due to the widespread use of increasingly sensitive imaging techniques that have enhanced the detection of thyroid nodules. Fine-needle aspiration cytology remains the diagnostic gold standard; however, 15–25% of samples fall into indeterminate Bethesda categories (III and IV), for which the traditional approach often involves diagnostic surgery, despite around 75% of these nodules ultimately prove to be benign. Advances in the genetic characterization of thyroid tumors, together with the development of next generation sequencing (NGS) technologies, have enabled the introduction of molecular tests aimed at improving preoperative risk stratification. Key genetic alterations include mutations in BRAF, the RAS family, the TERT promoter, and rearrangements involving RET, NTRK, and ALK, all of which have diagnostic and prognostic implications. Several commercial assays have been developed, employing methodologies including NGS, RNA sequencing, microRNA profiling, and qPCR. These tests demonstrate good sensitivity and high negative predictive value, helping to reduce unnecessary surgeries and better guide therapeutic decisions. Alongside commercial platforms, the high cost and limited accessibility of such tests have stimulated the development of increasingly robust in-house panels. Integrating molecular profiling with clinical and ultrasound findings now enables a more personalized approach to the management of indeterminate thyroid nodules, including surgery, mini-invasive treatments or active surveillance. Future perspectives include multi-omic and artificial intelligence approaches which may further enhance diagnostic accuracy and cost-effectiveness. L’incidence du cancer de la thyroïde a augmenté ces dernières décennies, principalement grâce à l’utilisation généralisée de techniques d’imagerie de plus en plus sensibles qui ont amélioré la détection des nodules thyroïdiens. La cytologie par aspiration à l’aiguille fine reste la référence diagnostique ; cependant, 15 à 25 % des échantillons appartiennent à des catégories Bethesda indéterminées (III et IV), pour lesquelles l’approche traditionnelle implique souvent une chirurgie diagnostique, bien qu’environ 75 % de ces nodules se révèlent finalement bénignes. Les avancées dans la caractérisation génétique des tumeurs thyroïdiennes, ainsi que le développement des technologies de séquençage de nouvelle génération (NGS), ont permis l’introduction de tests moléculaires visant à améliorer la stratification du risque préopératoire. Les principales altérations génétiques incluent des mutations dans BRAF, la famille RAS, le promoteur TERT, ainsi que des réarrangements impliquant RET, NTRK et ALK, qui ont tous des implications diagnostiques et pronostiques. Plusieurs tests commerciaux ont été développés, utilisant des méthodologies telles que NGS, séquençage ARN, profilage microARN et qPCR. Ces tests démontrent une bonne sensibilité et une forte valeur prédictive négative, aidant à réduire les interventions chirurgicales inutiles et à mieux orienter les décisions thérapeutiques. Parallèlement aux plateformes commerciales, le coût élevé et l’accessibilité limitée de ces tests ont stimulé le développement de panneaux internes de plus en plus robustes. L’intégration du profilage moléculaire avec les résultats cliniques et échographies permet désormais une approche plus personnalisée de la prise en charge des nodules thyroïdiens indéterminés, incluant la chirurgie, les traitements mini-invasifs ou la surveillance active. Les perspectives futures incluent les approches multi-omiques et l’intelligence artificielle qui pourraient encore améliorer la précision diagnostique et la rentabilité.
Fibrosis-Driven Surgical Risk After Thyroid Nodule Ablation: Quantitative Clinicopathological Determinants of Complications in Post-Ablative Thyroidectomy—A Retrospective Cohort Study
Daqi Zhang, Alvino Boero, Giacomo Gazzano, Andrea Satta, Laura Fugazzola, Carla Colombo, Francesco Brucchi, Gianlorenzo Dionigi
World Journal of Surgery, 2026
Background Thermal ablation is increasingly used for selected benign and low‐risk thyroid nodules, yet some patients still require thyroidectomy for regrowth, persistent symptoms, or new oncologic concern. The surgical and pathological impact of ablation‐induced remodeling remains incompletely defined. We aimed to characterize postablation thyroidectomy outcomes and identify histological correlates of perioperative morbidity. Methods We conducted a single‐center retrospective cohort study of patients undergoing thyroidectomy after radiofrequency or ethanol ablation (2021–2025). Clinical and ablation‐related variables were collected, and intraoperative neuromonitoring was routinely used. Primary outcomes were recurrent laryngeal nerve (RLN) palsy, reoperative hematoma, and hypoparathyroidism. Surgical specimens underwent blinded dual‐pathologist assessment with semiquantitative scoring of sclerosis, necrosis, and residual viability, from which a maturation index was derived. Associations with complications were analyzed using nonparametric methods. Outcomes were descriptively compared with a contemporaneous nonablated cohort for contextual purposes. Results Thirty‐one patients were included. Postoperative complications occurred in 22.6% of ablated cases. Histological analysis demonstrated moderate sclerosis (19.2%), necrosis (14.6%), and high residual viability (66.1%), with frequent pericapsular inflammatory changes and preserved capsule integrity. Sclerosis was the only parameter significantly associated with postoperative complications (30.0% vs. 16.9% and p = 0.008), whereas nodule size, ablation‐to‐surgery interval, and incidental carcinoma were not predictive. The maturation index increased with time after ablation but did not discriminate complication risk. Exploratory fibrosis‐weighted metrics suggested potential risk thresholds, although these findings remain hypothesis‐generating given the limited sample size. Conclusions Thyroidectomy after prior ablation is feasible in experienced centers but may be technically demanding and associated with modestly increased procedural complexity. Mature sclerosis represents the principal histological correlate of perioperative morbidity, linking fibrotic remodeling to operative risk. These findings support centralization of postablation thyroid surgery in high‐volume units with routine neuromonitoring and specialized pathology and highlight the need for larger prospective studies to validate fibrosis‐based risk stratification tools.
High-dose intravenous methylprednisolone is effective in subacute thyroiditis unresponsive to oral steroids
Simone Rodolfi, Guia Maria Vannucchi, Michela Perrino, Carla Colombo, Danila Covelli, Luca Persani, Laura Fugazzola, Irene Campi
European Thyroid Journal, 2026
Objective Subacute thyroiditis (SAT) relapsing or refractory to standard of care oral prednisone (OP) therapy is rare, but affected patients experience significant discomfort due to prolonged and uncontrolled neck pain. Here, we report the efficacy of high-dose intravenous methylprednisolone (IVMP) therapy in the treatment of such cases. Methods In this pilot study, we included 14 patients diagnosed with SAT in the period 2014–2024, in a single center. Therapy consisted of 500 mg of IVMP, divided into two weekly infusions and titrated down based on clinical response. Thyroid function tests, thyroid ultrasound, and inflammatory markers were assessed at baseline and throughout the follow-up up to 3–6 months after IVMP discontinuation. Results At baseline, 4 and 10 patients had thyrotoxicosis or were euthyroid, respectively. The median (IQR) duration of treatment was 26 days (21–38). At the end of the treatment, we observed a complete clinical, ultrasonographic, and biochemical response in twelve patients (86%), whereas thirteen (93%) had immediate resolution of neck pain and thyrotoxicosis. Only one patient did not improve at the end of IVMP protocol, and she was the only one experiencing a delayed remission with persistent hypothyroidism. Mild grade 1 and 2 adverse events (hyperglycemia, arterial hypertension, and neutrophilia) occurred in 8 out of 14 patients. Conclusion IVMP therapy resulted in a rapid clinical and ultrasonographic improvement in most patients with relapsing SAT unresponsive to oral steroids. This response allowed for a shorter treatment duration, with good tolerability, minimal adverse events, and a low incidence of hypothyroidism during follow-up.
Patient-Derived in Vitro Models Reveal Insights into Medullary Thyroid Cancer Microenvironment and Resistance to Tyrosine Kinase Inhibitors
Elisa Stellaria Grassi, Viola Ghiandai, Germano Gaudenzi, Elena Massardi, Valentina Cirello, Erika Carbone, Davide Gentilini, Sarah Uraghi, Giacomo Gazzano, Gianlorenzo Dionigi, Carla Colombo, Giovanni Vitale, Laura Fugazzola, Luca Persani
Thyroid Official Journal of the American Thyroid Association, 2026
Background: Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy with a 10-year mortality rate up to 50%. Current therapies for metastatic MTC comprise various tyrosine-kinase inhibitors, but resistance often appears due to the need for lifelong treatments. Like in other tumors, genetic, epigenetic, post-transcriptional, post-translational, and cell–cell interaction events influence drug response. However, progress in understanding MTC biology is limited by the lack of reliable in vivo and in vitro models. This study aims to develop a patient-derived model faithfully reproducing the microenvironmental alterations present in MTC. Methods: We applied a two-step protocol consisting of a first phase in which primary cells are cultivated as multicellular spheroids and a second phase in which they are switched to adherent cultures. After evaluation of the genetic background by targeted Next Generation Sequencing, we characterized our cells phenotype by examining a panel of stem/progenitor-related markers, the secretory abilities by ELISAs, the drug response by proliferation assays, the in vivo angiogenic and invasiveness by the use of zebrafish model, the in vitro invasivity by Matrigel Dome assays and the spatial variation of stem/progenitor marker in both 3D cell models and tissue samples by confocal microscopy. Results: Our model allowed the establishment of eight MTC patient-derived cell lines with different genetic backgrounds. The cultures faithfully reproduced the changes in stem and progenitor markers that we detected in our cohort of MTC tissue samples and could be successfully xenotransplanted in zebrafish model, showing both angiogenetic and invasive properties. Drug screening assays revealed the potential of our model for the study of patient-specific responses, as we were able to identify different candidate regulators of the sensitivity to currently available therapies for MTC. Conclusions: Our two-step protocol successfully generated primary MTC lines that maintain high plasticity, can be cultivated for several passages, and recreate the heterogeneity observed in patients’ tissues. Our model will offer a robust platform for preclinical drug testing and mechanistic studies, addressing a longstanding gap in MTC research. It enables exploration of tumor microenvironment interactions and personalized therapeutic responses, supporting progress beyond current genomic-driven frameworks.
Genetic factors in thyroid disease
Laura Fugazzola, Marina Muzza
Encyclopedia of Endocrine Diseases, 2026
Thyroglobulin
Laura Fugazzola, Marina Muzza
Encyclopedia of Endocrine Diseases, 2026
Thyroid gland development, molecular biology
Laura Fugazzola, Marina Muzza
Encyclopedia of Endocrine Diseases, 2026
Clinical presentation and outcomes of medullary thyroid cancer in two European countries: impact of diagnostic strategies
Daniele Ceruti, Han J Bonenkamp, Carla Colombo, Martin Gotthardt, Simone De Leo, Antonius E van Herwaarden, Petronella B Ottevanger, Romana T Netea-Maier, Laura Fugazzola
European Thyroid Journal, 2026
Objective To evaluate differences in clinical presentation, diagnostic and therapeutic modalities, and outcomes in two cohorts of patients with sporadic medullary thyroid carcinoma (MTC) from reference centres in Italy and the Netherlands. The two centres have different diagnostic approaches, including the use of routine calcitonin (CT) measurement. Methods A total of 165 patients (106 Italian and 59 Dutch) were retrospectively included. The cohorts were compared overall and according to diagnostic modality. Logistic regression and multivariable Cox proportional hazards models were used, as appropriate, to assess progression-free survival (PFS), disease-specific survival (DSS) and associated risk factors. Results The Dutch cohort presented with more advanced disease, as per higher TNM, AJCC staging, and significantly higher CT both preoperative and at last visit ( P < 0.001). Dutch patients received more frequently second operations, radiotherapy, and systemic treatments. PFS and 10-year DSS were significantly lower in the Dutch cohort ( P < 0.001 and P 0.01). Tumour size, nodal involvement, presence of distant metastases at diagnosis and progression during the follow-up were independent strong predictors of shorter PFS and DSS. Patients diagnosed via routine CT measurement showed a less aggressive presentation and more favourable outcome. Conclusion We compared for the first time two MTC cohorts from countries with different diagnostic and therapeutic approaches. Our data contribute to highlighting an association between routine CT measurement and MTC presentation and outcome, while suggesting that caution should be exercised when interpreting the differences among countries in MTC prevalence and clinical features.
Physical activity and systemic treatment outcomes in advanced thyroid cancer
Carla Colombo, Daniele Ceruti, Fabrizio Cervellini, Massimiliano Succi, Simone De Leo, Matteo Trevisan, Claudia Moneta, Marina Lugaresi, Gianlorenzo Dionigi, Giacomo Gazzano, Luca Persani, Laura Fugazzola
Endocrine Oncology, 2026
Introduction Physical activity interventions could play a critical role in tolerance and outcome during anti-neoplastic therapy. Aim This study aims to evaluate the role of physical activity and its maintenance on treatment safety and efficacy in patients with advanced thyroid cancer. Methods We enrolled 28 patients with advanced thyroid cancer, treated with kinase inhibitor therapy for a median follow-up of 26 months. Three modified long-form International Physical Activity Questionnaires were administered before treatment, at an intermediate follow-up point and at the last follow-up point. Metabolic equivalents were calculated at each time point. Tumour response was evaluated according to RECIST, version 1.1. Results Patients inactive at baseline experienced more treatment interruptions during both the first (85 vs 30%, P = 0.01) and second half of the follow-up period (85 vs 47%, P = 0.08) and had more frequently a progressive disease (42 vs 14%, P = 0.15), compared to those who were mildly or highly active. Patients who declined their physical activity during treatment had more treatment interruptions (100 vs 31%, P = 0.006), more adverse events considering both the number (>5) and the grade (≥3) (100 vs 31%, P = 0.006 and 100 vs 38%, P = 0.01), more hospitalization due to toxicities (66 vs 8%, P = 0.008) and a more progressive disease (40 vs 8%, P = 0.09). The number of toxicities was inversely correlated with metabolic equivalents lost ( r = −0.15, P = 0.04). Conclusion This is the first study showing that maintaining adequate physical activity levels is associated with better treatment tolerance and outcomes in advanced thyroid cancer patients on kinase inhibitor therapy, supporting the need for prospective prehabilitation trials.
Clinical relevance of the thyroid differentiation score (TDS) in benign and malignant thyroid tumors
Marina Muzza, Carla Colombo, Gabriele Pogliaghi, Erika Carbone, Laura Ermellino, Massimiliano Succi, Claudia Moneta, Gianlorenzo Dionigi, Davide Gentilini, Guia Vannucchi, Giacomo Gazzano, Luca Persani, Laura Fugazzola
Endocrine Related Cancer, 2025
The thyroid differentiation score (TDS), calculated on the expression levels of 16 thyroid function genes, was reported to be lower in BRAF-like than in RAS-like papillary thyroid cancers, but scanty data are available in either other malignant histotypes or in benign thyroid nodules. The aims of the present study were to investigate the clinical relevance of the TDS in a large series of thyroid neoplasms, and its possible role in the differential diagnosis of cytologically indeterminate nodules. The TDS was calculated in 126 differentiated, 20 undifferentiated, 9 non-invasive follicular thyroid neoplasms with papillary-like nuclear features, and 44 benign neoplasms. Overall, TDS significantly and progressively decreased from benign to differentiated and undifferentiated tumors ( P < 0.0001). A lower TDS was found in differentiated tumors with higher stage ( P = 0.006) and American Thyroid Association (ATA) risk ( P = 0.03), radio-iodine resistance ( P = 0.008), and disease persistence ( P = 0.009). Moreover, TDS independently correlated with progression-free survival, after adjusting for age at diagnosis and ATA risk ( P = 0.02). In Bethesda III and IV nodules, the TDS was significantly lower in nodules found to be malignant at histology compared to benign neoplasms ( P = 0.004). The combination of TDS with genetic test showed a sensitivity of 78.4%, a specificity of 77.3%, a PPV of 80%, and a NPV of 75.6% ( P = 0.001). In conclusion, we found a lower TDS in malignant compared to benign thyroid neoplasms, and demonstrated the prognostic role of TDS in differentiated tumors. These findings could preoperatively improve both the differential diagnosis of cytologically indeterminate nodules and the selection of the best surgical approach.
International Consensus on the Requirements for Definitions of Complete Remission and Recurrence of Differentiated Thyroid Cancer: a Delphi Study (ICON-DTC)
Daniël J van de Berg, Hanneke M van Santen, Sarah C Clement, Menno R Vriens, A S Paul van Trotsenburg, Eveline Bruinstroop, Schelto Kruijff, Robin P Peeters, Frederik A Verburg, Romana Netea-Maier, Els J M Nieveen van Dijkum, Laura Fugazzola, Marek Dedecjus, W Edward Visser, Kenneth K Baidoo, Joep P M Derikx, Anton F Engelsman, , Adekunle Daniel, Agnieszka Czarniecka, Alessandra Cassio, Alexis Vrachimis, Anca Sirbu, andrea frasoldati, Andrea Contarino, Andrej Belančić, Andrew J Bauer, Anna Crescenzi, Anna Konney, Anna M Sawka, Annamária Erdei, Antje Redlich, Marialuisa Appetecchia, Arseny Semenov, Ashok R Shaha, Berna O Evranos, MC Burlacu, Pietro G Calò, Camille Buffet, Carmine De Bartolomeis, Catherine A Dinauer, Corina E Andreescu, Dario Tumino, Doina Piciu, Domenico Albano, Elena Chobankova, Elin H Naderi, Ellen Kapiteijn, Esther Willemse, Ferenc Gyory, Flavia Magri, Florence van Ryckeghem, Francesco Ferraù, Franco Grimaldi, Françoise Borson-Chazot, furio pacini, Gabriella Pellegriti, Gerasimos P Sykiotis, Gerdi Tuli, Gerlof D Valk, Gesthimani Mintziori, Gianni Bocca, Giulia Brigante, Giuseppe Costante, Giuseppe Fanetti, Gloria Marquina, Gordana Horvatić-Herceg, François Gorostidi, Greg Randolph, Ohanyan Haykanush, Iryna O Kostitska, james suliburk, Jan Krátký, Jan Podoba, Jan Zedenius, Jolanta Krajewska, Jon Wadsley, Jonathan D Wasserman, Juan C Galofré, Julie Hallanger- Johnson, Katerina Kopeckova, Katerina Saltiki, Kenneth Kojo Baidoo, Koen M A Dreijerink, Laszlo Hegedüs, Laura Fugazzola, Laura D Locati, Livia Lamartina, Luca Giovanella, Luca Persani, Luisa de Sanctis, Malek Mnejja, Malgorzata Trofimiuk-Müldner, Marcin Barczynski, Marco Raffaelli, Maria C Vigone, Maria G Castagna, Maria Grazia Maratta, Maria João Bugalho, Maria Sandström, Marie-Louise Healy, Mario Salvi, Mark Gruppetta, Martin Almquist, MT Stegenga, Michele N Minuto, Miklós Tóth, Miloš Žarković, Monica L Gheorghiu, Montserrat Negre Busó, Brooke Puttergill, Nicholas Reed, Nicole D Bouvy, Nikola Besic, Oleksandr Nechai, Özer Makay, Pablo Valderrabano, Paul A Onakoya, Peter Angelos, Petra Petranović Ovčariček, Petros Perros, Kristien Boelaert, Thomas J Musholt, Radu Mihai, Ramon R J P van Eekeren, Renuka P Dias, Roman Chernikov, Ronald R de Krijger, Patrick O Rosselet, Roussanka Kovatcheva, Salvatore Cannavò, Sam Van Slycke, Silvia A Eskes, Steven I Sherman, Steven G Waguespack, Thera P Links, Tessa Malaika van Ginhoven, Tiago nunes da silva, Tijana Ičin, Timm Denecke, Tobias Zingg, Ulla Feldt- Rasmussen, Valeriano Leite
European Journal of Endocrinology, 2025
Prospective Validation of ATA Risk Score for Papillary Thyroid Microcarcinoma: An ITCO Real-World Study
Simone De Leo, Giulia Brigante, Silvia D’Elia, Simona Censi, Bruno Madeo, Silvia Morelli, Alice Nervo, Andrea Repaci, Clotilde Sparano, Ilaria Stramazzo, Camilla Virili, Francesco Bertagna, Francesco Dondi, Efisio Puxeddu, Edoardo Talpacci, Maria Chiara Zatelli, Maria Rosaria Ambrosio, Francesco Felicetti, Alessandro Piovesan, Luisa Petrone, Virginia Adornato, Matteo Trevisan, Laura Fugazzola, Chiara Mele, Marco Zavattaro, Erica Solaroli, Nicola Salituro, Mattia Rossi, Loredana Pagano, Alessandra Colapinto, Cristina Basso, Graziano Ceresini, Michela Marina, Umberto Crocetti, Michela Massa, Maurilio Deandrea, Francesca Retta, Giovanna Spiazzi, Nicoletta Rolli, Rocco Bruno, Antonella Carbone, Mario Rotondi, Flavia Magri, Poupak Fallahi, Maria Grazia Chiofalo, Maria Giulia Santaguida, Salvatore Monti, Tommaso Porcelli, Roberto Castello, Alfonso Sagnella, Cristina Clausi, Giulia Di Dalmazi, Dario Tumino, Andrea Palermo, Antonio Brunetti, Andrea Lania, Andrea Liverani, Cosimo Durante, Umberto Ferraro Petrillo, Marco Alfo’, Sebastiano Filetti, Giorgio Grani
Journal of Clinical Endocrinology and Metabolism, 2025
TP53 Alterations Are Associated With Poor Response to Lenvatinib in Patients With Advanced Thyroid Cancer
Valentina Cirello, Carla Colombo, Delfina Tosi, Alessandro Manzo, Maria Orietta Borghi, Umberto Gianelli, Giacomo Gazzano, Stefano Ferrero, Gianlorenzo Dionigi, Luca Persani, Laura Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2025
Genetic modification of the AJCC classification of papillary thyroid cancer: an international, multicentre, retrospective cohort study
Mingzhao Xing, Shuhuang Lin, Aarti Mathur, Ying Li, Bela Bendlova, Vlasta Kuklikova, Miguel Melo, Tito Teles Jesus, Paula Soares, Carla Colombo, Laura Fugazzola, Norisato Mitsutake, Michiko Matsuse, Ayaka Sako, Ana Patricia Estrada-Florez, Luis G Carvajal-Carmona, Mabel E Bohórquez, Caterina Mian, Federica Vianello, Christine J O'Neill, Roderick Clifton-Bligh, Agnieszka Czarniecka, Barbara Jarzab, Chan Kwon Jung, Bayu Brahma, Paul W Ladenson, Young Joo Park
Lancet Oncology, 2025
Clinical and Pathological Factors Associated with Disease Persistence in Pediatric Patients with Differentiated Thyroid Carcinoma
Simone De Leo, Valeria Bottici, Gabriella Pellegriti, Marco Russo, Caterina Mian, et al.
Thyroid, 2025
Differentiated thyroid cancer in two European referral centres: impact of different diagnostic and therapeutic strategies
Daniele Ceruti, Petronella B Ottevanger, Simone De Leo, Han J Bonenkamp, Carla Colombo, Martin Gotthardt, Laura Fugazzola, Romana T Netea-Maier
European Thyroid Journal, 2025
Endocrinological toxicities related to immunotherapy combinations for advanced renal cell carcinoma: Practical expert-based management recommendations
Carla Colombo, Simone De Leo, Ilaria Campisi, Erica Palesandro, Fabio Turco, Consuelo Buttigliero, Laura Fugazzola, Marcello Tucci
Critical Reviews in Oncology Hematology, 2025
Exploring the tumor suppressor role of RIN1 in familial thyroid carcinoma
Luna Picello, Mattia Dalle Nogare, Daniele Puggina, Cecilia Salvoro, Gianmaria Pennelli, Germano Gaudenzi, Silvia Carra, Monica Oldani, Davide Gentilini, Laura Fugazzola, Antongiulio Faggiano, Giovanni Vitale, Gianluca Occhi, Giovanni Vazza
Endocrine Related Cancer, 2025
Changing the paradigm: lobectomy for sporadic medullary thyroid cancer
Marina Lugaresi, Claudia Moneta, Giulia Saruggia, Gianlorenzo Dionigi, Giacomo Gazzano, Laura Fugazzola
European Thyroid Journal, 2025
Will the autofluorescence take over inadvertent parathyroidectomy? Results from a multicentre cohort study
Diego Barbieri, Pietro Indelicato, Simone De Leo, Claudia Moneta, Silvia Coccia, Giacomo Gazzano, Leone Giordano, Francesca Lira Luce, Davide Canta, Laura Fugazzola, Mario Bussi, Gianlorenzo Dionigi, Matteo Trevisan
Updates in Surgery, 2025
Gender impact on safety and efficacy in lenvatinib treated patients with radioiodine-refractory differentiated thyroid cancer (GISEL study)
Giulia Puliani, Marta Bianchini, Carlotta Giani, Laura Valerio, Alice Nervo, Giulia Sapuppo, Giorgio Grani, Cristina Dalmiglio, Simone De Leo, Rosa Lauretta, Marilda Mormando, Irene Terrenato, Stefania Zovato, Laura Fugazzola, Maria Grazia Castagna, Cosimo Durante, Gabriella Pellegriti, Emanuela Arvat, Rossella Elisei, Marialuisa Appetecchia
European Thyroid Journal, 2025
Beyond Malignancy Risk Stratification: FNAC Report Anticipates Thyroid Cancer Staging. Insights From Recent Studies
Mario Rotondi, Mayumi Endo, Marsida Teliti, Anna Crescenzi, Irina Azaryan, Laura Croce, Rossella Elisei, Laura Fugazzola, Edmund S Cibas, Pierpaolo Trimboli, Jennifer A Sipos
Journal of Clinical Endocrinology and Metabolism, 2025
Utility of ultra-portable ultrasound devices for the risk-stratification of thyroid dysfunctions in an emergency setting
Irene Campi, Laura Fugazzola
Journal of Endocrinological Investigation, 2025
Formulations for the Replacement Therapy of Hypothyroidism: State of the Art and Perspectives
Marina Lugaresi, Laura Fugazzola
Thyroid Diabetes and Osteoporosis the Bermuda Triangle, 2025
Additional Techniques
Fulvio Basolo, Giovanni Tallini, Giancarlo Troncone, Silvia Taccogna, Laura Fugazzola, Efisio Puxeddu
Italian Consensus for the Classification and Reporting of Thyroid Cytology, 2025
Characterization of EpCAM in thyroid cancer biology by three-dimensional spheroids in vitro model
Viola Ghiandai, Elisa Stellaria Grassi, Giacomo Gazzano, Laura Fugazzola, Luca Persani
Cancer Cell International, 2024
dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe
Joana S. Rodrigues, Miguel Chenlo, Susana B. Bravo, Sihara Perez-Romero, Maria Suarez-Fariña, Tomas Sobrino, Rebeca Sanz-Pamplona, Román González-Prieto, Manuel Narciso Blanco Freire, Ruben Nogueiras, Miguel López, Laura Fugazzola, José Manuel Cameselle-Teijeiro, Clara V. Alvarez
Nature Communications, 2024
Correction to: Camrelizumab-based induction chemoimmunotherapy in locally advanced stage hypopharyngeal carcinoma: phase II clinical trial (Nature Communications, (2024), 15, 1, (5251), 10.1038/s41467-024-49121-3)
Hongli Gong, Shu Tian, Hao Ding, Lei Tao, Li Wang, Jie Wang, Tian Wang, Xiaohui Yuan, Yu Heng, Ming Zhang, Yong Shi, Chengzhi Xu, Chunping Wu, Shengzi Wang, Liang Zhou
Nature Communications, 2024
Correction to: dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe (Nature Communications, (2024), 15, 1, (3736), 10.1038/s41467-024-47751-1)
Joana S. Rodrigues, Miguel Chenlo, Susana B. Bravo, Sihara Perez-Romero, Maria Suarez-Fariña, Tomas Sobrino, Rebeca Sanz-Pamplona, Román González-Prieto, Manuel Narciso Blanco Freire, Ruben Nogueiras, Miguel López, Laura Fugazzola, José Manuel Cameselle-Teijeiro, Clara V. Alvarez
Nature Communications, 2024
Extra-nuclear TERT counteracts oxidative stress and promotes progression in papillary thyroid carcinoma
Marina Muzza, Gabriele Pogliaghi, Carla Colombo, Elisa Stellaria Grassi, Erika Carbone, Sonia Palazzo, Francesco Frattini, Giacomo Gazzano, Luca Persani, Laura Fugazzola
Translational Research, 2024
Impact of systemic treatments for advanced thyroid cancer on the adrenal cortex
Carla Colombo, Daniele Ceruti, Massimiliano Succi, Simone De Leo, Matteo Trevisan, Claudia Moneta, Laura Fugazzola
European Thyroid Journal, 2024
Thyroid cancer and endocrine disruptive chemicals: a case-control study on per-fluoroalkyl substances and other persistent organic pollutants
Valentina Cirello, Marina Lugaresi, Claudia Moneta, Patrice Dufour, Alessandro Manzo, Erika Carbone, Carla Colombo, Laura Fugazzola, Corinne Charlier, Catherine Pirard
European Thyroid Journal, 2024
Radiofrequency ablation is an effective treatment for Bethesda III thyroid nodules without genetic alterations
Laura Fugazzola, Maurilio Deandrea, Stefano Borgato, Marco Dell’Acqua, Francesca Retta, Alberto Mormile, Chiara Carzaniga, Giacomo Gazzano, Gabriele Pogliaghi, Marina Muzza, Luca Persani
European Thyroid Journal, 2024
Molecular Alterations and Comprehensive Clinical Management of Oncocytic Thyroid Carcinoma: A Review and Multidisciplinary 2023 Update
Lindsay A. Bischoff, Ian Ganly, Laura Fugazzola, Erin Buczek, William C. Faquin, Bryan R. Haugen, Bryan McIver, Caitlin P. McMullen, Kate Newbold, Daniel J. Rocke, Marika D. Russell, Mabel Ryder, Peter M. Sadow, Eric Sherman, Maisie Shindo, David C. Shonka, Michael C. Singer, Brendan C. Stack, Lori J. Wirth, Richard J. Wong, Gregory W. Randolph
JAMA Otolaryngology Head and Neck Surgery, 2024
Improved guidance is needed to optimise diagnostics and treatment of patients with thyroid cancer in Europe
Christelle de la Fouchardière, Laura Fugazzola, Laura D. Locati, Clara V. Alvarez, Robin P. Peeters, Pilar Camacho, Iris M. Simon, Barbara Jarząb, Romana Netea-Maier
Endocrine, 2024
Clinical Outcomes of Thermal Ablation Re-Treatment of Benign Thyroid Nodules: A Multicenter Study from the Italian Minimally Invasive Treatments of the Thyroid Group
Stella Bernardi, Valentina Rosolen, Fabio Barbone, Stefano Borgato, Maurilio Deandrea, Pierpaolo De Feo, Laura Fugazzola, Giovanni Gambelunghe, Roberto Negro, Salvatore Oleandri, Giampaolo Papi, Enrico Papini, Francesca Retta, Ruth Rossetto, Daniela Sansone, Giuseppe Serra, Luca Maria Sconfienza, Luigi Solbiati, Stefano Spiezia, Fulvio Stacul, Giovanni Mauri
Thyroid, 2024
A Prospective Multicenter Study Examining the Relationship Between Thyroid Cancer Treatment Outcomes and the Presence of Autoimmune Thyroiditis
Simone De Leo, Silvia D'Elia, Giorgio Grani, Francesco Dondi, Francesco Bertagna, Efisio Puxeddu, Silvia Morelli, Alessandro Piovesan, Alice Nervo, Maria Chiara Zatelli, Irene Gagliardi, Maria Teresa Samà, Gianluca Aimaretti, Umberto Crocetti, Michela Massa, Maurilio Deandrea, Francesca Retta, Loredana Pagano, Mattia Rossi, Erica Solaroli, Luciano Pezzullo, Maria Grazia Chiofalo, Alfredo Pontecorvi, Celestino Pio Lombardi, Alessandro Antonelli, Armando Patrizio, Ilaria Messuti, Flavia Magri, Giovanna Spiazzi, Graziano Ceresini, Rocco Bruno, Clotilde Sparano, Marco Centanni, Anna Crescenzi, Giovanni Tallini, Vincenzo Marotta, Bruno Madeo, Caterina Mian, Sebastiano Filetti, Cosimo Durante, Laura Fugazzola
Thyroid, 2023
Letter to the Editor: Tumor Lysis Syndrome During Selpercatinib Treatment in a Patient with Medullary Thyroid Cancer
Simone De Leo, Matteo Trevisan, Giulia Vanessa Re Sartò, Claudia Moneta, Marta Pirovano, Carla Colombo, Laura Cosmai, Laura Fugazzola
Thyroid, 2023
Fetal cell microchimerism and susceptibility to COVID-19 disease in women
Valentina Cirello, Marina Lugaresi, Alessandro Manzo, Eva Balla, Gerardina Fratianni, Francesca Solari, Luca Persani, Laura Fugazzola, Irene Campi
Infection, 2023
Correction: Fetal cell microchimerism and susceptibility to COVID-19 disease in women (Infection, (2023), 51, 4, (1071-1078), 10.1007/s15010-023-02006-x)
Valentina Cirello, Marina Lugaresi, Alessandro Manzo, Eva Balla, Gerardina Fratianni, Francesca Solari, Luca Persani, Laura Fugazzola, Irene Campi
Infection, 2023
Management of hypertension during lenvatinib for advanced thyroid cancer: a suggested diagnostic and therapeutic algorithm
Carla Colombo, Daniele Ceruti, Simone De Leo, Grzegorz Bilo, Matteo Trevisan, Noemi Giancola, Claudia Moneta, Gianfranco Parati, Luca Persani, Laura Fugazzola
European Thyroid Journal, 2023
Medullary thyroid cancer - An update
Laura Fugazzola
Best Practice and Research Clinical Endocrinology and Metabolism, 2023
Hypocalcemia during Lenvatinib Treatment for Advanced Thyroid Cancer: Clinical Features and Management in a Real-Life Setting
Simone De Leo, Matteo Trevisan, Carla Colombo, Claudia Moneta, Noemi Giancola, Laura Fugazzola
Thyroid, 2023
A Data-Driven Approach to Refine Predictions of Differentiated Thyroid Cancer Outcomes: A Prospective Multicenter Study
Giorgio Grani, Michele Gentili, Federico Siciliano, Domenico Albano, Valentina Zilioli, Silvia Morelli, Efisio Puxeddu, Maria Chiara Zatelli, Irene Gagliardi, Alessandro Piovesan, Alice Nervo, Umberto Crocetti, Michela Massa, Maria Teresa Samà, Chiara Mele, Maurilio Deandrea, Laura Fugazzola, Barbara Puligheddu, Alessandro Antonelli, Ruth Rossetto, Annamaria D’Amore, Graziano Ceresini, Roberto Castello, Erica Solaroli, Marco Centanni, Salvatore Monti, Flavia Magri, Rocco Bruno, Clotilde Sparano, Luciano Pezzullo, Anna Crescenzi, Caterina Mian, Dario Tumino, Andrea Repaci, Maria Grazia Castagna, Vincenzo Triggiani, Tommaso Porcelli, Domenico Meringolo, Laura Locati, Giovanna Spiazzi, Giulia Di Dalmazi, Aris Anagnostopoulos, Stefano Leonardi, Sebastiano Filetti, Cosimo Durante
Journal of Clinical Endocrinology and Metabolism, 2023
FAM83B is involved in thyroid cancer cell differentiation and migration
Valentina Cirello, Elisa Stellaria Grassi, Gabriele Pogliaghi, Viola Ghiandai, Laura Ermellino, Marina Muzza, Giacomo Gazzano, Luca Persani, Carla Colombo, Laura Fugazzola
Scientific Reports, 2022
Oxidative Stress Correlates with More Aggressive Features in Thyroid Cancer
Marina Muzza, Gabriele Pogliaghi, Carla Colombo, Erika Carbone, Valentina Cirello, Sonia Palazzo, Francesco Frattini, Davide Gentilini, Giacomo Gazzano, Luca Persani, Laura Fugazzola
Cancers, 2022
Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe
Kamil Demircan, Thilo Samson Chillon, Tommy Bracken, Ilaria Bulgarelli, Irene Campi, Gijs Du Laing, Samira Fafi-Kremer, Laura Fugazzola, Alejandro Abner Garcia, Raban Heller, David J. Hughes, Louis Ide, Georg Jochen Klingenberg, Pawel Komarnicki, Zbigniew Krasinski, Alain Lescure, Patrick Mallon, Arash Moghaddam, Luca Persani, Mirko Petrovic, Marek Ruchala, Morgane Solis, Linos Vandekerckhove, Lutz Schomburg
Frontiers in Immunology, 2022
Persistent Thyroid Carcinoma and Pregnancy: Outcomes in an Italian Series and Review of the Literature
Carla Colombo, Simone De Leo, Noemi Giancola, Matteo Trevisan, Daniele Ceruti, Francesco Frattini, Luca Persani, Laura Fugazzola
Cancers, 2022
Impact of thyroid function screening in a large cohort of patients admitted to an emergency department
Irene Campi, Giovanni Battista Perego, Antonella Ravogli, Francesca Santafede, Federica Sileo, Antonella Dubini, Gianfranco Parati, Luca Persani, Laura Fugazzola
Internal and Emergency Medicine, 2022
Lenvatinib-induced hypocalcaemia due to transient primary hypoparathyroidism
Matteo Trevisan, Carla Colombo, Noemi Giancola, Claudia Moneta, Gianlorenzo Dionigi, Laura Fugazzola, Simone De Leo
Endocrine, 2022
Thyroid cancer harboring PTEN and TP53 mutations: A peculiar molecular and clinical case report
Carla Colombo, Gabriele Pogliaghi, Delfina Tosi, Marina Muzza, Gaetano Bulfamante, Luca Persani, Laura Fugazzola, Valentina Cirello
Frontiers in Oncology, 2022
Tackling Thyroid Cancer in Europe—The Challenges and Opportunities
Denis Horgan, Dagmar Führer-Sakel, Paula Soares, Clara V. Alvarez, Laura Fugazzola, Romana T. Netea-Maier, Barbara Jarzab, Marta Kozaric, Beate Bartes, James Schuster-Bruce, Luigino Dal Maso, Martin Schlumberger, Furio Pacini
Healthcare Switzerland, 2022
Unilateral Surgery for Medullary Thyroid Carcinoma: Seeking for Clinical Practice Guidelines
Daqi Zhang, Carla Colombo, Hui Sun, Hoon Yub Kim, Antonella Pino, Simone De Leo, Giacomo Gazzano, Luca Persani, Gianlorenzo Dionigi, Laura Fugazzola
Frontiers in Endocrinology, 2022
Daily Management of Patients on Multikinase Inhibitors’ Treatment
Carla Colombo, Simone De Leo, Matteo Trevisan, Noemi Giancola, Anna Scaltrito, Laura Fugazzola
Frontiers in Oncology, 2022
Thyroid pathology and female fertility: Myth or reality?
Guia Vannucchi, Luca Persani, Laura Fugazzola
Annales D Endocrinologie, 2022
Which Is the Best Endoscopic Procedure for Thyroid Gland?
Gianlorenzo Dionigi, Luigi Boni, Laura Fugazzola, Hoon Yub Kim, Paolo Miccoli
Annals of Surgical Oncology, 2022
Minimally-invasive treatments for benign thyroid nodules: recommendations for information to patients and referring physicians by the Italian Minimally-Invasive Treatments of the Thyroid group
Giovanni Mauri, Stella Bernardi, Andrea Palermo, Roberto Cesareo, , Enrico Papini, Luigi Solbiati, Daniele Barbaro, Salvatore Monti, Maurilio Deandrea, Laura Fugazzola, Giovanni Gambelunghe, Roberto Negro, Stefano Spiezia, Fulvio Stacul, Luca Maria Sconfienza, Marco Cavallaro, Gaetano Achille, Vito Cantisani, Luca Cozzaglio, Anna Crescenzi, Francesco De Cobelli, Roberto Garberoglio, Gioacchino Giugliano, Luca Persani, Bruno Raggiunti, Ettore Seregni, Dominique Van Doorne, Andrea Frasoldati, Chiara Carzaniga, Celestino Pio Lombardi, Giampaolo Papi, Rinaldo Guglielmi, Franco Orsi, Rosa Cervelli, Chiara Barbieri, Pierpaolo Trimboli, Dario Monzani
Endocrine, 2022
Image-guided thermal ablation in autonomously functioning thyroid nodules. A retrospective multicenter three-year follow-up study from the Italian Minimally Invasive Treatment of the Thyroid (MITT) Group
Giovanni Mauri, Enrico Papini, Stella Bernardi, Daniele Barbaro, Roberto Cesareo, Pierpaolo De Feo, Maurilio Deandrea, Laura Fugazzola, Giovanni Gambelunghe, Gabriele Greco, Carmelo Messina, Salvatore Monti, Alberto Mormile, Roberto Negro, Chiara Offi, Andrea Palermo, Luca Persani, Federica Presciuttini, Luigi Alessandro Solbiati, Stefano Spiezia, Fulvio Stacul, Marco Viganò, Luca Maria Sconfienza
European Radiology, 2022
Therapy With Different Dose Regimens of Rituximab in Patients With Active Moderate-To-Severe Graves’ Orbitopathy
Irene Campi, Guia Vannucchi, Ilaria Muller, Elisa Lazzaroni, Nicola Currò, Martina Dainese, Benedetta Montacchini, Danila Covelli, Claudio Guastella, Lorenzo Pignataro, Laura Fugazzola, Maura Arosio, Mario Salvi
Frontiers in Endocrinology, 2022
How can we prevent disease relapse in Graves’ orbitopathy after immunosuppressive treatment?
Irene Campi, Laura Fugazzola
Expert Review of Endocrinology and Metabolism, 2022
Minimal Extrathyroidal Extension in Predicting 1-Year Outcomes: A Longitudinal Multicenter Study of Low-to-Intermediate-Risk Papillary Thyroid Carcinoma (ITCO#4)
Raffaella Forleo, Giorgio Grani, Marco Alfò, Valentina Zilioli, Raffaele Giubbini, Maria Chiara Zatelli, Irene Gagliardi, Alessandro Piovesan, Alberto Ragni, Silvia Morelli, Efisio Puxeddu, Loredana Pagano, Maurilio Deandrea, Graziano Ceresini, Massimo Torlontano, Barbara Puligheddu, Alessandro Antonelli, Marco Centanni, Laura Fugazzola, Giovanna Spiazzi, Salvatore Monti, Ruth Rossetto, Fabio Monzani, Giovanni Tallini, Anna Crescenzi, Clotilde Sparano, Rocco Bruno, Andrea Repaci, Dario Tumino, Luciano Pezzullo, Celestino Pio Lombardi, Umberto Ferraro Petrillo, Sebastiano Filetti, Cosimo Durante, Maria Grazia Castagna
Thyroid, 2021
Clinical Consequences of Variable Results in the Measurement of Free Thyroid Hormones: Unusual Presentation of a Family with a Novel Variant in the THRB Gene Causing Resistance to Thyroid Hormone Syndrome
Irene Campi, Maura Agostini, Federica Marelli, Tiziana de Filippis, Beatriz Romartinez-Alonso, Odelia Rajanayagam, Giuditta Rurale, Ilaria Gentile, Federica Spagnolo, Massimiliano Andreasi, Francesco Ferraù, Salvatore Cannavò, Laura Fugazzola, Krishna V. Chatterjee, Luca Persani
European Thyroid Journal, 2021
BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer
Yubing Tao, Fei Wang, Xiaopei Shen, Guangwu Zhu, Rengyun Liu, David Viola, Rossella Elisei, Efisio Puxeddu, Laura Fugazzola, Carla Colombo, Barbara Jarzab, Agnieszka Czarniecka, Alfred K Lam, Caterina Mian, Federica Vianello, Linwah Yip, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Christine J O’Neill, Mark S Sywak, Roderick Clifton-Bligh, Bela Bendlova, Vlasta Sýkorová, Shihua Zhao, Yangang Wang, Mingzhao Xing
Journal of Clinical Endocrinology and Metabolism, 2021
Basal and Calcium-Stimulated Procalcitonin for the Diagnosis of Medullary Thyroid Cancers: Lights and Shadows
Simona Censi, Marta Di Stefano, Andrea Repaci, Teresa Benvenuti, Jacopo Manso, Uberto Pagotto, Maurizio Iacobone, Susi Barollo, Loris Bertazza, Francesca Galuppini, Clara Benna, Gianmaria Pennelli, Mario Plebani, Diego Faggian, Carla Colombo, Laura Fugazzola, Caterina Mian
Frontiers in Endocrinology, 2021
Post-surgical ablative or adjuvant radioiodine therapy has no impact on outcome in 1–4 cm differentiated thyroid cancers without extrathyroidal extension
Simone De Leo, Matteo Trevisan, Carla Colombo, Giacomo Gazzano, Sonia Palazzo, Leonardo Vicentini, Luca Persani, Laura Fugazzola
Journal of Clinical Medicine, 2021
ASO Author Reflections: Total Thyroidectomy Versus Lobectomy for Differentiated Thyroid Cancer
Carla Colombo, Simone De Leo, Laura Fugazzola
Annals of Surgical Oncology, 2021
Total Thyroidectomy Versus Lobectomy for Thyroid Cancer: Single-Center Data and Literature Review
Carla Colombo, Simone De Leo, Marta Di Stefano, Matteo Trevisan, Claudia Moneta, Leonardo Vicentini, Laura Fugazzola
Annals of Surgical Oncology, 2021
High Prevalence and Conservative Management of Acute Cholecystitis during Lenvatinib for Advanced Thyroid Cancer
Marta Di Stefano, Carla Colombo, Simone De Leo, Michela Perrino, Mauro Viganò, Luca Persani, Laura Fugazzola
European Thyroid Journal, 2021
Combined mutational and clonality analyses support the existence of intra-tumor heterogeneity in papillary thyroid cancer
Marina Muzza, Gabriele Pogliaghi, Luca Persani, Laura Fugazzola, Carla Colombo
Journal of Clinical Medicine, 2021
Erratum: 2021 European Thyroid Association Guideline on Thyroid Disorders prior to and during Assisted Reproduction (European Thyroid Journal (2020) 9 (281-295) DOI: 10.1159/000512790)
European Thyroid Journal, 2021
European Thyroid Association and Cardiovascular and Interventional Radiological Society of Europe 2021 Clinical Practice Guideline for the Use of Minimally Invasive Treatments in Malignant Thyroid Lesions
Giovanni Mauri, Laszlo Hegedüs, Steven Bandula, Roberto Luigi Cazzato, Agnieszka Czarniecka, Oliver Dudeck, Laura Fugazzola, Romana Netea-Maier, Gilles Russ, Göran Wallin, Enrico Papini
European Thyroid Journal, 2021
Lenvatinib as first-line treatment for advanced thyroid cancer: long progression-free survival
Simone De Leo, Marta Di Stefano, Luca Persani, Laura Fugazzola, Carla Colombo
Endocrine, 2021
The spectrum of thyroid function tests during hospitalization for SARS COV-2 infection
Irene Campi, Ilaria Bulgarelli, Antonella Dubini, Giovanni Battista Perego, Elena Tortorici, Camilla Torlasco, Erminio Torresani, Lorenzo Rocco, Luca Persani, Laura Fugazzola
European Journal of Endocrinology, 2021
Efficacy Profile and Safety of Very Low-Dose Rituximab in Patients with Graves' Orbitopathy
Guia Vannucchi, Irene Campi, Danila Covelli, Nicola Currò, Elisa Lazzaroni, Andrea Palomba, Davide Soranna, Antonella Zambon, Laura Fugazzola, Ilaria Muller, Claudio Guastella, Mario Salvi
Thyroid, 2021
The relationship between liver histology and thyroid function tests in patients with nonalcoholic fatty liver disease (NAFLD)
Roberta D'Ambrosio, Irene Campi, Marco Maggioni, Riccardo Perbellini, Enza Giammona, Roberta Stucchi, Marta Borghi, Elisabetta Degasperi, Annalisa De Silvestri, Luca Persani, Laura Fugazzola, Pietro Lampertico
Plos One, 2021
Personalized treatment for differentiated thyroid cancer: Current data and new perspectives
Carla COLOMBO, Noemi GIANCOLA, Laura FUGAZZOLA
Minerva Endocrinology, 2021
New genetics in congenital hypothyroidism
Athanasia Stoupa, Dulanjalee Kariyawasam, Marina Muzza, Tiziana de Filippis, Laura Fugazzola, Michel Polak, Luca Persani, Aurore Carré
Endocrine, 2021
The thyroid risk score (TRS) for nodules with indeterminate cytology
Carla Colombo, Marina Muzza, Gabriele Pogliaghi, Sonia Palazzo, Guia Vannucchi, Leonardo Vicentini, Luca Persani, Giacomo Gazzano, Laura Fugazzola
Endocrine Related Cancer, 2021
Basal and stimulated calcitonin for the diagnosis of medullary thyroid cancer: updated thresholds and safety assessment
L. Fugazzola, M. Di Stefano, S. Censi, A. Repaci, C. Colombo, F. Grimaldi, F. Magri, U. Pagotto, M. Iacobone, L. Persani, C. Mian
Journal of Endocrinological Investigation, 2021
Congenital Hypothyroidism: A 2020-2021 Consensus Guidelines Update - An ENDO-European Reference Network Initiative Endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology
Paul van Trotsenburg, Athanasia Stoupa, Juliane Léger, Tilman Rohrer, Catherine Peters, Laura Fugazzola, Alessandra Cassio, Claudine Heinrichs, Veronique Beauloye, Joachim Pohlenz, Patrice Rodien, Regis Coutant, Gabor Szinnai, Philip Murray, Beate Bartés, Dominique Luton, Mariacarolina Salerno, Luisa de Sanctis, Mariacristina Vigone, Heiko Krude, Luca Persani, Michel Polak
Thyroid, 2021
2021 European Thyroid Association Guideline on Thyroid Disorders prior to and during Assisted Reproduction
Kris Poppe, Peter Bisschop, Laura Fugazzola, Gesthimani Minziori, David Unuane, Andrea Weghofer
European Thyroid Journal, 2021
Quantification of Global Ocular Motility Impairment in Graves' Orbitopathy by Measuring Eye Muscle Ductions
Irene Campi, Nicola Currò, Guia Vannucchi, Danila Covelli, Simona Simonetta, Laura Fugazzola, Davide Dazzi, Lorenzo Pignataro, Claudio Guastella, Elisa Lazzaroni, Giacinta Pirola, Mario Salvi
Thyroid, 2021
Real-World Performance of the American Thyroid Association Risk Estimates in Predicting 1-Year Differentiated Thyroid Cancer Outcomes: A Prospective Multicenter Study of 2000 Patients
Giorgio Grani, Maria Chiara Zatelli, Marco Alfò, Teresa Montesano, Massimo Torlontano, Silvia Morelli, Maurilio Deandrea, Alessandro Antonelli, Cecilia Francese, Graziano Ceresini, Fabio Orlandi, Carolina Adele Maniglia, Rocco Bruno, Salvatore Monti, Maria Giulia Santaguida, Andrea Repaci, Giovanni Tallini, Laura Fugazzola, Fabio Monzani, Raffaele Giubbini, Ruth Rossetto, Caterina Mian, Anna Crescenzi, Dario Tumino, Loredana Pagano, Luciano Pezzullo, Celestino Pio Lombardi, Emanuela Arvat, Luisa Petrone, Maria Grazia Castagna, Giovanna Spiazzi, Domenico Salvatore, Domenico Meringolo, Erica Solaroli, Fabio Monari, Flavia Magri, Vincenzo Triggiani, Roberto Castello, Cesare Piazza, Roberta Rossi, Umberto Ferraro Petrillo, Sebastiano Filetti, Cosimo Durante
Thyroid, 2021
Clinical and Genetic Features of a Large Monocentric Series of Familial Non-Medullary Thyroid Cancers
Valentina Cirello, Carla Colombo, Olga Karapanou, Gabriele Pogliaghi, Luca Persani, Laura Fugazzola
Frontiers in Endocrinology, 2021
Adipokines and Thyroid Malignancies
Carla Colombo, Laura Fugazzola
Thyroid Obesity and Metabolism Exploring Links Between Thyroid Function Obesity Metabolism and Lifestyle, 2021
Fine needle aspiration wash out for thyroglobulin determination in the differential diagnosis of lung lesions
Ilaria Righi, Lorenzo Rosso, Giacomo Grisorio, Laura Fugazzola
Endocrine, 2021
Recent advances in the management of anaplastic thyroid cancer
Simone De Leo, Matteo Trevisan, Laura Fugazzola
Thyroid Research, 2020
The molecular and gene/miRNA expression profiles of radioiodine resistant papillary thyroid cancer
Carla Colombo, Emanuela Minna, Chiara Gargiuli, Marina Muzza, Matteo Dugo, Loris De Cecco, Gabriele Pogliaghi, Delfina Tosi, Gaetano Bulfamante, Angela Greco, Laura Fugazzola, Maria Grazia Borrello
Journal of Experimental and Clinical Cancer Research, 2020
The Differential Diagnosis of Discrepant Thyroid Function Tests: Insistent Pitfalls and Updated Flow-Chart Based on a Long-Standing Experience
Irene Campi, Danila Covelli, Carla Moran, Laura Fugazzola, Chiara Cacciatore, Fabio Orlandi, Gabriella Gallone, Krishna Chatterjee, Paolo Beck-Peccoz, Luca Persani
Frontiers in Endocrinology, 2020
Molecular markers for the classification of cytologically indeterminate thyroid nodules
M. Muzza, C. Colombo, G. Pogliaghi, O. Karapanou, L. Fugazzola
Journal of Endocrinological Investigation, 2020
Intratumoral genetic heterogeneity in papillary thyroid cancer: Occurrence and clinical significance
Laura Fugazzola, Marina Muzza, Gabriele Pogliaghi, Mario Vitale
Cancers, 2020
Nodular Thyroid Disease in the Era of Precision Medicine
Dario Tumino, Giorgio Grani, Marta Di Stefano, Maria Di Mauro, Maria Scutari, Teresa Rago, Laura Fugazzola, Maria Grazia Castagna, Fabio Maino
Frontiers in Endocrinology, 2020
Body Composition and Leptin/Ghrelin Levels during Lenvatinib for Thyroid Cancer
Simone De Leo, Carla Colombo, Marta Di Stefano, Antonella Dubini, Silvia Cozzi, Luca Persani, Laura Fugazzola
European Thyroid Journal, 2020
BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma
Kyeong J. Kim, Sin G. Kim, Jie Tan, Xiaopei Shen, David Viola, Rossella Elisei, Efisio Puxeddu, Laura Fugazzola, Carla Colombo, Barbara Jarzab, Agnieszka Czarniecka, Alfred K. Lam, Caterina Mian, Federica Vianello, Linwah Yip, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Christine J. O'Neill, Mark S. Sywak, Roderick Clifton-Bligh, Bela Bendlova, Vlasta Sýkorová, Mingzhao Xing
European Journal of Cancer, 2020
Genetic variants of PARP4 gene and PARP4P2 pseudogene in patients with multiple primary tumors including thyroid cancer
Valentina Cirello, Carla Colombo, Gabriele Pogliaghi, Maria Carla Proverbio, Stefania Rossi, Elena Mussani, Delfina Tosi, Gaetano Bulfamante, Emanuela Bonoldi, Giorgio Gherardi, Luca Persani, Laura Fugazzola
Mutation Research Fundamental and Molecular Mechanisms of Mutagenesis, 2019
2019 European Thyroid Association Guidelines for the Treatment and Follow-Up of Advanced Radioiodine-Refractory Thyroid Cancer
Laura Fugazzola, Rossella Elisei, Dagmar Fuhrer, Barbara Jarzab, Sophie Leboulleux, Kate Newbold, Jan Smit
European Thyroid Journal, 2019
Absence of the MAP2K5 germline variants c.G961A and c.T1100C in a wide series of familial nonmedullary thyroid carcinoma Italian families
Valentina Cirello, Carla Colombo, Luca Persani, Laura Fugazzola
International Journal of Cancer, 2019
Baseline and stimulated calcitonin: Thresholds for the diagnosis of medullary thyroid cancer
Laura Fugazzola
Annales D Endocrinologie, 2019
DUOX2/DUOXA2 Mutations Frequently Cause Congenital Hypothyroidism that Evades Detection on Newborn Screening in the United Kingdom
Catherine Peters, Adeline K. Nicholas, Erik Schoenmakers, Greta Lyons, Shirley Langham, Eva G. Serra, Neil J. Sebire, Marina Muzza, Laura Fugazzola, Nadia Schoenmakers
Thyroid, 2019
Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study
Frederic Castinetti, Steven G Waguespack, Andreas Machens, Shinya Uchino, Kornelia Hasse-Lazar, Gabriella Sanso, Tobias Else, Sarka Dvorakova, Xiao Ping Qi, Rossella Elisei, Ana Luisa Maia, John Glod, Delmar Muniz Lourenço, Nuria Valdes, Jes Mathiesen, Nelson Wohllk, Tushar R Bandgar, Delphine Drui, Marta Korbonits, Maralyn R Druce, Caroline Brain, Tom Kurzawinski, Atila Patocs, Maria Joao Bugalho, Andre Lacroix, Philippe Caron, Patricia Fainstein-Day, Francoise Borson Chazot, Marc Klein, Thera P Links, Claudio Letizia, Laura Fugazzola, Olivier Chabre, Letizia Canu, Regis Cohen, Antoine Tabarin, Anita Spehar Uroic, Dominique Maiter, Sandrine Laboureau, Caterina Mian, Mariola Peczkowska, Frederic Sebag, Thierry Brue, Delphine Mirebeau-Prunier, Laurence Leclerc, Birke Bausch, Amandine Berdelou, Akihiro Sukurai, Petr Vlcek, Jolanta Krajewska, Marta Barontini, Carla Vaz Ferreira Vargas, Laura Valerio, Lucieli Ceolin, Srivandana Akshintala, Ana Hoff, Christian Godballe, Barbara Jarzab, Camilo Jimenez, Charis Eng, Tsuneo Imai, Martin Schlumberger, Elizabeth Grubbs, Henning Dralle, Hartmut P Neumann, Eric Baudin
Lancet Diabetes and Endocrinology, 2019
Impact of Mutation Density and Heterogeneity on Papillary Thyroid Cancer Clinical Features and Remission Probability
Carla Colombo, Marina Muzza, Maria Carla Proverbio, Delfina Tosi, Davide Soranna, Chiara Pesenti, Stefania Rossi, Valentina Cirello, Simone De Leo, Nicola Fusco, Monica Miozzo, Gaetano Bulfamante, Leonardo Vicentini, Stefano Ferrero, Antonella Zambon, Silvia Tabano, Laura Fugazzola
Thyroid, 2019
Pulsed intravenous methylprednisolone combined with oral steroids as a treatment for poorly responsive type 2 amiodarone-induced thyrotoxicosis
Irene Campi, Giovanni B Perego, Antonella Ravogli, Antonella Groppelli, Gianfranco Parati, Luca Persani, Laura Fugazzola
European Journal of Endocrinology, 2019
Minimally-invasive treatments for benign thyroid nodules: a Delphi-based consensus statement from the Italian minimally-invasive treatments of the thyroid (MITT) group
Enrico Papini, Claudio Maurizio Pacella, Luigi Alessandro Solbiati, Gaetano Achille, Daniele Barbaro, Stella Bernardi, Vito Cantisani, Roberto Cesareo, Arturo Chiti, Luca Cozzaglio, Anna Crescenzi, Francesco De Cobelli, Maurilio Deandrea, Laura Fugazzola, Giovanni Gambelunghe, Roberto Garberoglio, Gioacchino Giugliano, Livio Luzi, Roberto Negro, Luca Persani, Bruno Raggiunti, Francesco Sardanelli, Ettore Seregni, Martina Sollini, Stefano Spiezia, Fulvio Stacul, Dominique Van Doorne, Luca Maria Sconfienza, Giovanni Mauri
International Journal of Hyperthermia, 2019
Primary Adrenal Insufficiency during Lenvatinib or Vandetanib and Improvement of Fatigue after Cortisone Acetate Therapy
Carla Colombo, Simone De Leo, Marta Di Stefano, Guia Vannucchi, Luca Persani, Laura Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2018
Segmental Maternal UPD of Chromosome 7q in a Patient With Pendred and Silver Russell Syndromes-Like Features
Valentina Cirello, Valentina Giorgini, Chiara Castronovo, Susan Marelli, Ester Mainini, Alessandra Sironi, Maria Paola Recalcati, Marco Pessina, Daniela Giardino, Lidia Larizza, Luca Persani, Palma Finelli, Silvia Russo, Laura Fugazzola
Frontiers in Genetics, 2018
BRAF V600E confers male sex disease-specific mortality risk in patients with papillary thyroid cancer
Fei Wang, Shihua Zhao, Xiaopei Shen, Guangwu Zhu, Rengyun Liu, David Viola, Rossella Elisei, Efisio Puxeddu, Laura Fugazzola, Carla Colombo, Barbara Jarzab, Agnieszka Czarniecka, Alfred K. Lam, Caterina Mian, Federica Vianello, Linwah Yip, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Christine J. O’Neill, Mark S. Sywak, Roderick Clifton-Bligh, Bela Bendlova, Vlasta Sýkorová, Yangang Wang, Mingzhao Xing
Journal of Clinical Oncology, 2018
Genetics and management of congenital hypothyroidism
Luca Persani, Giuditta Rurale, Tiziana de Filippis, Elena Galazzi, Marina Muzza, Laura Fugazzola
Best Practice and Research Clinical Endocrinology and Metabolism, 2018
Correction to: Radioiodine ablation with 1,850 MBq in association with rhTSH in patients with differentiated thyroid cancer (Journal of Endocrinological Investigation, (2014), 37, 8, (709-714), 10.1007/s40618-014-0088-3)
Alberto S. Tresoldi, Laura F. Sburlati, Marcello Rodari, Mink S. Schinkelshoek, Michela Perrino, Simone De Leo, Laura Montefusco, Paolo Colombo, Maura Arosio, Andrea Gerardo Antonio Lania, Laura Fugazzola, Arturo Chiti
Journal of Endocrinological Investigation, 2018
MassARRAY-based simultaneous detection of hotspot somatic mutations and recurrent fusion genes in papillary thyroid carcinoma: the PTC-MA assay
Chiara Pesenti, Marina Muzza, Carla Colombo, Maria Carla Proverbio, Claudia Farè, Stefano Ferrero, Monica Miozzo, Laura Fugazzola, Silvia Tabano
Endocrine, 2018
Italian consensus on diagnosis and treatment of differentiated thyroid cancer: joint statements of six Italian societies
F. Pacini, F. Basolo, R. Bellantone, G. Boni, M. A. Cannizzaro, M. De Palma, C. Durante, R. Elisei, G. Fadda, A. Frasoldati, L. Fugazzola, R. Guglielmi, C. P. Lombardi, P. Miccoli, E. Papini, G. Pellegriti, L. Pezzullo, A. Pontecorvi, M. Salvatori, E. Seregni, P. Vitti
Journal of Endocrinological Investigation, 2018
BRAF V600E mutation-assisted risk stratification of solitary intrathyroidal papillary thyroid cancer for precision treatment
Yueye Huang, Shen Qu, Guangwu Zhu, Fei Wang, Rengyun Liu, Xiaopei Shen, David Viola, Rossella Elisei, Efisio Puxeddu, Laura Fugazzola, Carla Colombo, Barbara Jarzab, Agnieszka Czarniecka, Alfred K Lam, Caterina Mian, Federica Vianello, Linwah Yip, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Christine J O’Neill, Mark S Sywak, Roderick Clifton-Bligh, Bela Bendlova, Vlasta Sýkorová, Mingzhao Xing
Journal of the National Cancer Institute, 2018
Tumor and normal thyroid spheroids: From tissues to Zebrafish
Valentina Cirello, Germano Gaudenzi, Elisa S. Grassi, Carla Colombo, Leonardo Vicentini, Stefano Ferrero, Luca Persani, Giovanni Vitale, Laura Fugazzola
Minerva Endocrinologica, 2018
Circulating miR-375 as a novel prognostic marker for metastatic medullary thyroid cancer patients
Paola Romeo, Carla Colombo, Roberta Granata, Giuseppina Calareso, Ambra Vittoria Gualeni, Matteo Dugo, Loris De Cecco, Maria Grazia Rizzetti, Angela Zanframundo, Antonella Aiello, Maria Luisa Carcangiu, Annunziata Gloghini, Stefano Ferrero, Lisa Licitra, Angela Greco, Laura Fugazzola, Laura Deborah Locati, Maria Grazia Borrello
Endocrine Related Cancer, 2018
8th edition of the AJCC/TNM staging system of thyroid cancer: What to expect (ITCO#2)
Livia Lamartina, Giorgio Grani, Emanuela Arvat, Alice Nervo, Maria Chiara Zatelli, Roberta Rossi, Efisio Puxeddu, Silvia Morelli, Massimo Torlontano, Michela Massa, Rocco Bellantone, Alfredo Pontecorvi, Teresa Montesano, Loredana Pagano, Lorenzo Daniele, Laura Fugazzola, Graziano Ceresini, Rocco Bruno, Ruth Rossetto, Salvatore Tumino, Marco Centanni, Domenico Meringolo, Maria Grazia Castagna, Domenico Salvatore, Antonio Nicolucci, Giuseppe Lucisano, Sebastiano Filetti, Cosimo Durante
Endocrine Related Cancer, 2018
Patient age-associated mortality risk is differentiated by BRAF V600E status in papillary thyroid cancer
Xiaopei Shen, Guangwu Zhu, Rengyun Liu, David Viola, Rossella Elisei, Efisio Puxeddu, Laura Fugazzola, Carla Colombo, Barbara Jarzab, Agnieszka Czarniecka, Alfred K. Lam, Caterina Mian, Federica Vianello, Linwah Yip, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Christine J. O’Neill, Mark S. Sywak, Roderick Clifton-Bligh, Bela Bendlova, Vlasta Sýkorová, Mingzhao Xing
Journal of Clinical Oncology, 2018
Letter regarding the article: “Multiple HABP2 variants in familial papillary thyroid carcinoma: Contribution of a group of “thyroid-checked” controls” by Kern et al.
Carla Colombo, Laura Fugazzola, Marina Muzza, Maria Carla Proverbio, Valentina Cirello
European Journal of Medical Genetics, 2018
Thyroglobulin
Marina Muzza, Laura Fugazzola
Encyclopedia of Endocrine Diseases, 2018
Cancer
Valentina Cirello, Laura Fugazzola
Chimerism A Clinical Guide, 2018
Thyroid gland development, molecular biology
Marina. Muzza, Laura. Fugazzola
Encyclopedia of Endocrine Diseases, 2018
Genetic factors in thyroid disease
Marina Muzza, Laura Fugazzola
Encyclopedia of Endocrine Diseases, 2018
Radioiodine Therapy of Thyroid Cancer
Ettore Seregni, Alice Lorenzoni, Laura Fugazzola
Clinical Applications of Nuclear Medicine Targeted Therapy, 2018
Are Evidence-Based Guidelines Reflected in Clinical Practice? An Analysis of Prospectively Collected Data of the Italian Thyroid Cancer Observatory
Livia Lamartina, Cosimo Durante, Giuseppe Lucisano, Giorgio Grani, Rocco Bellantone, Celestino Pio Lombardi, Alfredo Pontecorvi, Emanuela Arvat, Francesco Felicetti, Maria C. Zatelli, Roberta Rossi, Efisio Puxeddu, Silvia Morelli, Massimo Torlontano, Umberto Crocetti, Teresa Montesano, Raffaele Giubbini, Fabio Orlandi, Gianluca Aimaretti, Fabio Monzani, Marco Attard, Cecilia Francese, Alessandro Antonelli, Paolo Limone, Ruth Rossetto, Laura Fugazzola, Domenico Meringolo, Rocco Bruno, Salvatore Tumino, Graziano Ceresini, Marco Centanni, Salvatore Monti, Domenico Salvatore, Giovanna Spiazzi, Caterina Mian, Luca Persani, Daniele Barbaro, Antonio Nicolucci, Sebastiano Filetti
Thyroid, 2017
Digenic DUOX1 and DUOX2 mutations in cases with congenital hypothyroidism
Zehra Aycan, Hakan Cangul, Marina Muzza, Veysel N Bas, Laura Fugazzola, V Krishna Chatterjee, Luca Persani, Nadia Schoenmakers
Journal of Clinical Endocrinology and Metabolism, 2017
The prognostic value of tumor multifocality in clinical outcomes of papillary thyroid cancer
Fei Wang, Xiaolong Yu, Xiaopei Shen, Guangwu Zhu, Yueye Huang, Rengyun Liu, David Viola, Rossella Elisei, Efisio Puxeddu, Laura Fugazzola, Carla Colombo, Barbara Jarzab, Agnieszka Czarniecka, Alfred K Lam, Caterina Mian, Federica Vianello, Linwah Yip, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Christine J O’Neill, Mark S Sywak, Roderick Clifton-Bligh, Bela Bendlova, Vlasta Sýkorová, Yangang Wang, Shiguo Liu, Jiajun Zhao, Shihua Zhao, Mingzhao Xing
Journal of Clinical Endocrinology and Metabolism, 2017
Thyroid volume and serum calcitonin changes during pregnancy
G. Vannucchi, D. Covelli, B. Vigo, M. Perrino, L. Mondina, L. Fugazzola
Journal of Endocrinological Investigation, 2017
Segregation and expression analyses of hyaluronan-binding protein 2 (HABP2): insights from a large series of familial non-medullary thyroid cancers and literature review
Carla Colombo, Marina Muzza, Maria Carla Proverbio, Giulia Ercoli, Michela Perrino, Valentina Cirello, Leonardo Vicentini, Stefano Ferrero, Laura Fugazzola
Clinical Endocrinology, 2017
Disorders of H2O2 generation
Marina Muzza, Laura Fugazzola
Best Practice and Research Clinical Endocrinology and Metabolism, 2017
Rewiring of the apoptotic TGF-β-SMAD/NFκB pathway through an oncogenic function of p27 in human papillary thyroid cancer
A R Garcia-Rendueles, J S Rodrigues, M E R Garcia-Rendueles, M Suarez-Fariña, S Perez-Romero, F Barreiro, I Bernabeu, J Rodriguez-Garcia, L Fugazzola, T Sakai, F Liu, J Cameselle-Teijeiro, S B Bravo, C V Alvarez
Oncogene, 2017
Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors
Valentina Cirello, Valentina Vaira, Elisa Stellaria Grassi, Valeria Vezzoli, Dario Ricca, Carla Colombo, Silvano Bosari, Leonardo Vicentini, Luca Persani, Stefano Ferrero, Laura Fugazzola
Oncotarget, 2017
Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer
Marina Muzza, Carla Colombo, Valentina Cirello, Michela Perrino, Leonardo Vicentini, Laura Fugazzola
Molecular and Cellular Endocrinology, 2016
Novel insights into the link between fetal cell microchimerism and maternal cancers
Valentina Cirello, Laura Fugazzola
Journal of Cancer Research and Clinical Oncology, 2016
Reply to the Letter to the Editor by Sollini M et al.
F. Pacini, R. Elisei, L. Fugazzola, M. Ferdeghini, S. Mariotti, G. Pellegriti
Journal of Endocrinological Investigation, 2016
The long-term impact of controlled ovarian hyperstimulation on thyroid function
Andrea. Busnelli, Edgardo. Somigliana, Stefania. Ferrari, Francesca. Filippi, Guia. Vannucchi, Laura. Fugazzola, Luigi. Fedele
Endocrine Practice, 2016
Recommendations for post-surgical thyroid ablation in differentiated thyroid cancer: A 2015 position statement of the Italian Society of Endocrinology
F. Pacini, E. Brianzoni, C. Durante, R. Elisei, M. Ferdeghini, L. Fugazzola, S. Mariotti, G. Pellegriti
Journal of Endocrinological Investigation, 2016
JAG1 loss-of-function variations as a novel predisposing event in the pathogenesis of congenital thyroid defects
Tiziana de Filippis, Federica Marelli, Gabriella Nebbia, Patrizia Porazzi, Sabrina Corbetta, Laura Fugazzola, Roberto Gastaldi, Maria Cristina Vigone, Roberta Biffanti, Daniela Frizziero, Luana Mandarà, Paolo Prontera, Mariacarolina Salerno, Mohamad Maghnie, Natascia Tiso, Giorgio Radetti, Giovanna Weber, Luca Persani
Journal of Clinical Endocrinology and Metabolism, 2016
Basal and stimulated calcitonin levels in patients with type 2 diabetes did not change during 1 year of Liraglutide treatment
Maria Elena Lunati, Valeria Grancini, Carla Colombo, Eva Palmieri, Veronica Resi, Michela Perrino, Emanuela Orsi, Laura Fugazzola
Metabolism Clinical and Experimental, 2016
Differential clinicopathological risk and prognosis of major papillary thyroid cancer variants
Xiaoguang Shi, Rengyun Liu, Fulvio Basolo, Riccardo Giannini, Xiaopei Shen, Di Teng, Haixia Guan, Zhongyan Shan, Weiping Teng, Thomas J. Musholt, Khawla Al-Kuraya, Laura Fugazzola, Carla Colombo, Electron Kebebew, Barbara Jarzab, Agnieszka Czarniecka, Bela Bendlova, Vlasta Sykorova, Manuel Sobrinho-Simões, Paula Soares, Young Kee Shong, Tae Yong Kim, Sonia Cheng, Sylvia L. Asa, David Viola, Rossella Elisei, Linwah Yip, Caterina Mian, Federica Vianello, Yangang Wang, Shihua Zhao, Gisele Oler, Janete M. Cerutti, Efisio Puxeddu, Shen Qu, Qing Wei, Huixiong Xu, Christine J. O'Neill, Mark S. Sywak, Roderick Clifton-Bligh, Alfred K Lam, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Hongyu Yu, Giovanni Tallini, Elizabeth H. Holt, Vasily Vasko, Mingzhao Xing
Journal of Clinical Endocrinology and Metabolism, 2016
Fetal cell microchimerism in papillary thyroid cancer: A role in the outcome of the disease
Valentina Cirello, Carla Colombo, Michela Perrino, Simone De Leo, Marina Muzza, Maria Antonia Maffini, Laura Fugazzola
International Journal of Cancer, 2015
Safety and tolerability of sorafenib in patients with radioiodine-refractory thyroid cancer
Francis Worden, Martin Fassnacht, Yuankai Shi, Tatiana Hadjieva, Françoise Bonichon, Ming Gao, Laura Fugazzola, Yuichi Ando, Yasuhisa Hasegawa, Do Joon Park, Young Kee Shong, Johannes W A Smit, John Chung, Christian Kappeler, Gerold Meinhardt, Martin Schlumberger, Marcia S Brose
Endocrine Related Cancer, 2015
Levothyroxine dose adjustment in hypothyroid women achieving pregnancy through IVF
Andrea Busnelli, Guia Vannucchi, Alessio Paffoni, Sonia Faulisi, Laura Fugazzola, Luigi Fedele, Edgardo Somigliana
European Journal of Endocrinology, 2015
Impact of estrogen and progesterone receptor expression on the clinical and molecular features of papillary thyroid cancer
Guia Vannucchi, Simone De Leo, Michela Perrino, Stefania Rossi, Delfina Tosi, Valentina Cirello, Carla Colombo, Gaetano Bulfamante, Leonardo Vicentini, Laura Fugazzola
European Journal of Endocrinology, 2015
Fetal cell microchimerism: A protective role in autoimmune thyroid diseases
Valentina Cirello, Roberta Rizzo, Milena Crippa, Irene Campi, Daria Bortolotti, Silvia Bolzani, Carla Colombo, Guia Vannucchi, Maria Antonia Maffini, Federica de Liso, Stefano Ferrero, Palma Finelli, Laura Fugazzola
European Journal of Endocrinology, 2015
Reference range of serum calcitonin in pediatric population
Maria G. Castagna, Laura Fugazzola, Fabio Maino, Danila Covelli, Silvia Memmo, Fausta Sestini, Carla Fioravanti, Chiara Ferraris Fusarini, Carlo Scapellato, Francesco Macchini, Gabriele Cevenini, Furio Pacini
Journal of Clinical Endocrinology and Metabolism, 2015
Telomerase in differentiated thyroid cancer: Promoter mutations, expression and localization
Marina Muzza, Carla Colombo, Stefania Rossi, Delfina Tosi, Valentina Cirello, Michela Perrino, Simone De Leo, Elisa Magnani, Elisa Pignatti, Beatrice Vigo, Manuela Simoni, Gaetano Bulfamante, Leonardo Vicentini, Laura Fugazzola
Molecular and Cellular Endocrinology, 2015
SP600125 has a remarkable anticancer potential against undifferentiated thyroid cancer through selective action on ROCK and p53 pathways
Elisa Stellaria Grassi, Valeria Vezzoli, Irene Negri, Árpád Lábadi, Laura Fugazzola, Giovanni Vitale, Luca Persani
Oncotarget, 2015
The modifier role of RET-G691S polymorphism in hereditary medullary thyroid carcinoma: Functional characterization and expression/penetrance studies
Carla Colombo, Emanuela Minna, Maria Grazia Rizzetti, Paola Romeo, Daniele Lecis, Luca Persani, Piera Mondellini, Marco A Pierotti, Angela Greco, Laura Fugazzola, Maria Grazia Borrello
Orphanet Journal of Rare Diseases, 2015
Rare diseases in clinical endocrinology: A taxonomic classification system
G. Marcucci, L. Cianferotti, P. Beck-Peccoz, M. Capezzone, F. Cetani, A. Colao, M. V. Davì, E. degli Uberti, S. Del Prato, R. Elisei, A. Faggiano, D. Ferone, C. Foresta, L. Fugazzola, E. Ghigo, G. Giacchetti, F. Giorgino, A. Lenzi, P. Malandrino, M. Mannelli, C. Marcocci, L. Masi, F. Pacini, G. Opocher, A. Radicioni, M. Tonacchera, R. Vigneri, M. C. Zatelli, M. L. Brandi
Journal of Endocrinological Investigation, 2015
Association between BRAF V600E mutation and recurrence of papillary thyroid cancer
Mingzhao Xing, Ali S. Alzahrani, Kathryn A. Carson, Young Kee Shong, Tae Yong Kim, David Viola, Rossella Elisei, Bela Bendlová, Linwah Yip, Caterina Mian, Federica Vianello, R. Michael Tuttle, Eyal Robenshtok, James A. Fagin, Efisio Puxeddu, Laura Fugazzola, Agnieszka Czarniecka, Barbara Jarzab, Christine J. O'Neill, Mark S. Sywak, Alfred K. Lam, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Hirotaka Nakayama, Roderick Clifton-Bligh, Giovanni Tallini, Elizabeth H. Holt, Vlasta Sýkorová
Journal of Clinical Oncology, 2015
Ultrasound-guided percutaneous ethanol injection in papillary thyroid cancer metastatic lymph-nodes
Guia Vannucchi, Danila Covelli, Michela Perrino, Simone De Leo, Laura Fugazzola
Endocrine, 2014
Positive Effect of Fetal Cell Microchimerism on Tumor Presentation and Outcome in Papillary Thyroid Cancer
Valentina Cirello, Laura Fugazzola
Chimerism, 2014
Feasibility study for the introduction of a new treatment Method for benign thyroid nodules in a teaching and research hospital
Marcella Longo, Ing Paolo Cassoli, Laura Fugazzola, Guia Vannucchi, Monica Lanzoni, Silvana Castaldi
Journal of Evaluation in Clinical Practice, 2014
Incidence of elevation of serum thyroid-stimulating hormone during controlled ovarian hyperstimulation for in vitro fertilization
Laura Benaglia, Andrea Busnelli, Edgardo Somigliana, Marta Leonardi, Guia Vannucchi, Simone De Leo, Laura Fugazzola, Guido Ragni, Luigi Fedele
European Journal of Obstetrics and Gynecology and Reproductive Biology, 2014
Radioiodine ablation with 1,850 MBq in association with rhTSH in patients with differentiated thyroid cancer
Alberto S. Tresoldi, Laura F. Sburlati, Marcello Rodari, Mink Schinkelshoek, Michela Perrino, Simone De Leo, Laura Montefusco, Paolo Colombo, Maura Arosio, Andrea Gerardo Antonio Lania, Laura Fugazzola, Arturo Chiti
Journal of Endocrinological Investigation, 2014
High-throughput mutation profiling improves diagnostic stratification of sporadic medullary thyroid carcinomas
Michele Simbolo, Caterina Mian, Susi Barollo, Matteo Fassan, Andrea Mafficini, Diogo Neves, Maria Scardoni, Gianmaria Pennelli, Massimo Rugge, Maria Rosa Pelizzo, Elisabetta Cavedon, Laura Fugazzola, Aldo Scarpa
Virchows Archiv, 2014
The clinical and molecular characterization of patients with dyshormonogenic congenital hypothyroidism reveals specific diagnostic clues for DUOX2 defects
M. Muzza, S. Rabbiosi, M. C. Vigone, I. Zamproni, V. Cirello, M. A. Maffini, K. Maruca, N. Schoenmakers, L. Beccaria, F. Gallo, S.-M. Park, P. Beck-Peccoz, L. Persani, G. Weber, L. Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2014
Refining calcium test for the diagnosis of medullary thyroid cancer: Cutoffs, procedures, and safety
Caterina Mian, Michela Perrino, Carla Colombo, Elisabetta Cavedon, Gianmaria Pennelli, Stefano Ferrero, Simone De Leo, Cristiano Sarais, Chiara Cacciatore, Gloria Irene Manfredi, Uberta Verga, Maurizio Iacobone, Loredana De Pasquale, Maria Rosa Pelizzo, Leonardo Vicentini, Luca Persani, Laura Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2014
Clinical and molecular analyses of thyroid cancer in patients treated for benign diseases
Simone De Leo, Michela Perrino, Sara Badiali, Stefania Rossi, Valentina Cirello, Carla Colombo, Delfina Tosi, Gianmaria Cantoni, Luca Poggi, Gaetano Bulfamante, Paolo Beck-Peccoz, Leonardo Vicentini, Laura Fugazzola
Endocrine Related Cancer, 2013
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
Mingzhao Xing, Ali S. Alzahrani, Kathryn A. Carson, David Viola, Rossella Elisei, Bela Bendlova, Linwah Yip, Caterina Mian, Federica Vianello, R. Michael Tuttle, Eyal Robenshtok, James A. Fagin, Efisio Puxeddu, Laura Fugazzola, Agnieszka Czarniecka, Barbara Jarzab, Christine J. O’Neill, Mark S. Sywak, Alfred K. Lam, Garcilaso Riesco-Eizaguirre, Pilar Santisteban, Hirotaka Nakayama, Ralph P. Tufano, Sara I. Pai, Martha A. Zeiger, William H. Westra, Douglas P. Clark, Roderick Clifton-Bligh, David Sidransky, Paul W. Ladenson, Vlasta Sykorova
JAMA, 2013
Genetic defects of hydrogen peroxide generation in the thyroid gland
Giovanna Weber, Sarah Rabbiosi, I. Zamproni, Laura Fugazzola
Journal of Endocrinological Investigation, 2013
Congenital hypothyroidism with eutopic thyroid gland: Analysis of clinical and biochemical features at diagnosis and after re-evaluation
Sarah Rabbiosi, Maria Cristina Vigone, Francesca Cortinovis, Ilaria Zamproni, Laura Fugazzola, Luca Persani, Carlo Corbetta, Giuseppe Chiumello, Giovanna Weber
Journal of Clinical Endocrinology and Metabolism, 2013
The optimal range of RET mutations to be tested: European comments to the guidelines of the American Thyroid Association
Laura Fugazzola, Simone De Leo, Michela Perrino
Thyroid Research, 2013
A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function
Eleonora Porcu, Marco Medici, Giorgio Pistis, Claudia B. Volpato, Scott G. Wilson, Anne R. Cappola, Steffan D. Bos, Joris Deelen, Martin den Heijer, Rachel M. Freathy, Jari Lahti, Chunyu Liu, Lorna M. Lopez, Ilja M. Nolte, Jeffrey R. O'Connell, Toshiko Tanaka, Stella Trompet, Alice Arnold, Stefania Bandinelli, Marian Beekman, Stefan Böhringer, Suzanne J. Brown, Brendan M. Buckley, Clara Camaschella, Anton J. M. de Craen, Gail Davies, Marieke C. H. de Visser, Ian Ford, Tom Forsen, Timothy M. Frayling, Laura Fugazzola, Martin Gögele, Andrew T. Hattersley, Ad R. Hermus, Albert Hofman, Jeanine J. Houwing-Duistermaat, Richard A. Jensen, Eero Kajantie, Margreet Kloppenburg, Ee M. Lim, Corrado Masciullo, Stefano Mariotti, Cosetta Minelli, Braxton D. Mitchell, Ramaiah Nagaraja, Romana T. Netea-Maier, Aarno Palotie, Luca Persani, Maria G. Piras, Bruce M. Psaty, Katri Räikkönen, J. Brent Richards, Fernando Rivadeneira, Cinzia Sala, Mona M. Sabra, Naveed Sattar, Beverley M. Shields, Nicole Soranzo, John M. Starr, David J. Stott, Fred C. G. J. Sweep, Gianluca Usala, Melanie M. van der Klauw, Diana van Heemst, Alies van Mullem, Sita H.Vermeulen, W. Edward Visser, John P. Walsh, Rudi G. J. Westendorp, Elisabeth Widen, Guangju Zhai, Francesco Cucca, Ian J. Deary, Johan G. Eriksson, Luigi Ferrucci, Caroline S. Fox, J. Wouter Jukema, Lambertus A. Kiemeney, Peter P. Pramstaller, David Schlessinger, Alan R. Shuldiner, Eline P. Slagboom, André G. Uitterlinden, Bijay Vaidya, Theo J. Visser, Bruce H. R. Wolffenbuttel, Ingrid Meulenbelt, Jerome I. Rotter, Tim D. Spector, Andrew A. Hicks, Daniela Toniolo, Serena Sanna, Robin P. Peeters, Silvia Naitza
Plos Genetics, 2013
Evidence of a low prevalence of ras mutations in a large medullary thyroid cancer series
Raffaele Ciampi, Caterina Mian, Laura Fugazzola, Barbara Cosci, Cristina Romei, Susi Barollo, Valentina Cirello, Valeria Bottici, Giulia Marconcini, Pelizzo Maria Rosa, Maria Grazia Borrello, Fulvio Basolo, Clara Ugolini, Gabriele Materazzi, Aldo Pinchera, Rossella Elisei
Thyroid, 2013
The widened use of exogenous stimulation with recombinant human TSH to treat metastatic thyroid carcinoma in Italy
Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2012
Modifications in the papillary thyroid cancer gene profile over the last 15 years
Cristina Romei, Laura Fugazzola, Efisio Puxeddu, Francesco Frasca, David Viola, Marina Muzza, Sonia Moretti, Maria Luisa Nicolosi, Carlotta Giani, Valentina Cirello, Nicola Avenia, Stefania Rossi, Paolo Vitti, Aldo Pinchera, Rossella Elisei
Journal of Clinical Endocrinology and Metabolism, 2012
A high percentage of BRAFV600E alleles in papillary thyroid carcinoma predicts a poorer outcome
Anna Guerra, Laura Fugazzola, Vincenzo Marotta, Massimo Cirillo, Stefania Rossi, Valentina Cirello, Irene Forno, Tania Moccia, Alfredo Budillon, Mario Vitale
Journal of Clinical Endocrinology and Metabolism, 2012
Radiometabolic therapy for metastatic thyroid carcinoma: Overview of the literature and rational bases for the use of recombinant human TSH
Minerva Medica, 2012
Microchimerism and endocrine disorders
Laura Fugazzola, Valentina Cirello, Paolo Beck-Peccoz
Journal of Clinical Endocrinology and Metabolism, 2012
Molecular and functional studies of 4 candidate loci in Pendred syndrome and nonsyndromic hearing loss
Valentina Cirello, Claudia Bazzini, Valeria Vezzoli, Marina Muzza, Simona Rodighiero, Pierangela Castorina, Antonia Maffini, Guido Bottà, Luca Persani, Paolo Beck-Peccoz, Giuliano Meyer, Laura Fugazzola
Molecular and Cellular Endocrinology, 2012
Comparison of calcium and pentagastrin tests for the diagnosis and follow-up of medullary thyroid cancer
Carla Colombo, Uberta Verga, Caterina Mian, Stefano Ferrero, Michela Perrino, Leonardo Vicentini, Davide Dazzi, Giuseppe Opocher, Maria Rosa Pelizzo, Paolo Beck-Peccoz, Laura Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2012
The primary occurrence of BRAFV600E is a rare clonal event in papillary thyroid carcinoma
Anna Guerra, Maria Rosaria Sapio, Vincenzo Marotta, Elisabetta Campanile, Stefania Rossi, Irene Forno, Laura Fugazzola, Alfredo Budillon, Tania Moccia, Gianfranco Fenzi, Mario Vitale
Journal of Clinical Endocrinology and Metabolism, 2012
Papillary thyroid carcinoma and infammation
Laura Fugazzola, Carla Colombo, Michela Perrino, Marina Muzza
Frontiers in Endocrinology, 2011
Lateralization of calcitonin measurements in the wash-out fluid from thyroid fine-needle aspiration: A useful tool for the diagnosis of C-cell-hyperplasia?
Vincenzo Rochira, Chiara Diazzi, Giulia Brigante, Luca Persani, Laura Fugazzola, Giulio Rossi, Cesare Carani
Thyroid, 2011
Absence of primary hypothyroidism and goiter in Slc26a4 (-/-) mice fed on a low iodine diet
Davide Calebiro, Patrizia Porazzi, Marco Bonomi, Simonetta Lisi, A. Grindati, et al.
Journal of Endocrinological Investigation, 2011
Life-threatening metabolic alkalosis in Pendred syndrome
Narayanan Kandasamy, Laura Fugazzola, Mark Evans, Krishna Chatterjee, Fiona Karet
European Journal of Endocrinology, 2011
Increased risk for non-autoimmune hypothyroidism in young patients with congenital heart defects
E. Passeri, M. Frigerio, T. De Filippis, R. Valaperta, P. Capelli, E. Costa, L. Fugazzola, F. Marelli, P. Porazzi, C. Arcidiacono, M. Carminati, B. Ambrosi, L. Persani, S. Corbetta
Journal of Clinical Endocrinology and Metabolism, 2011
DUOXS defects: Genotype-phenotype correlations
L. Fugazzola, M. Muzza, G. Weber, P. Beck-Peccoz, L. Persani
Annales D Endocrinologie, 2011
Fetal microchimerism as an explanation of disease
Laura Fugazzola, Valentina Cirello, Paolo Beck-Peccoz
Nature Reviews Endocrinology, 2011
Multiple endocrine neoplasia type 2 syndromes (MEN 2): Results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes (European Journal of Endocrinology 163 (301-308))
Cristina Romei, Stefano Mariotti, Laura Fugazzola, Augusto Taccaliti, Furio Pacini, Giuseppe Opocher, Caterina Mian, Maurizio Castellano, Ettore degli Uberti, Isabella Ceccherini, Nadia Cremonini, Ettore Seregni, Fabio Orlandi, Piero Ferolla, Efisio Puxeddu, Francesco Giorgino, Annamaria Colao, Paola Loli, Fabio Bondi, Barbara Cosci, Valeria Bottici, Antonello Cappai, Giovanni Pinna, Luca Persani, Verga Uberta, Marco Boscaro, Maria Grazia Castagna, Carlo Cappelli, Maria Chiara Zatelli, Antongiulio Faggiano, Giuseppe Francia, Maria Luisa Brandi, Alberto Falchetti, Aldo Pinchera, Rossella Elisei, _ _
European Journal of Endocrinology, 2010
Sorafenib-induced destructive thyroiditis
Massimo Iavarone, Michela Perrino, Mauro Viganò, Paolo Beck-Peccoz, Laura Fugazzola
Thyroid, 2010
Multiple endocrine neoplasia type 2 syndromes (MEN 2): Results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes
Cristina Romei, Stefano Mariotti, Laura Fugazzola, Augusto Taccaliti, Furio Pacini, Giuseppe Opocher, Caterina Mian, Maurizio Castellano, Ettore degli Uberti, Isabella Ceccherini, Nadia Cremonini, Ettore Seregni, Fabio Orlandi, Piero Ferolla, Efisio Puxeddu, Francesco Giorgino, Annamaria Colao, Paola Loli, Fabio Bondi, Barbara Cosci, Valeria Bottici, Antonello Cappai, Giovanni Pinna, Luca Persani, Verga Uberta, Marco Boscaro, Maria Grazia Castagna, Carlo Cappelli, Maria Chiara Zatelli, Antongiulio Faggiano, Giuseppe Francia, Maria Luisa Brandi, Alberto Falchetti, Aldo Pinchera, Rossella Elisei, _ _
European Journal of Endocrinology, 2010
Fetal cell microchimerism in papillary thyroid cancer: Studies in peripheral blood and tissues
Valentina Cirello, Michela Perrino, Carla Colombo, Marina Muzza, Marcello Filopanti, Leonardo Vicentini, Paolo Beck‐Peccoz, Laura Fugazzola
International Journal of Cancer, 2010
The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: Clinical and molecular studies
Marina Muzza, Debora Degl’Innocenti, Carla Colombo, Michela Perrino, Elena Ravasi, Stefania Rossi, Valentina Cirello, Paolo Beck‐Peccoz, Maria Grazia Borrello, Laura Fugazzola
Clinical Endocrinology, 2010
Four novel RET germline variants in exons 8 and 11 display an oncogenic potential in vitro
Marina Muzza, Daniela Cordella, Johny Bombled, Brigitte Bressac-de Paillerets, Fabiana Guizzardi, Zelia Francis, Paolo Beck-Peccoz, Martin Schlumberger, Luca Persani, Laura Fugazzola
European Journal of Endocrinology, 2010
Fetal cell microchimerism in human cancers
Laura Fugazzola, Valentina Cirello, Paolo Beck-Peccoz
Cancer Letters, 2010
Clinical and molecular features of differentiated thyroid cancer diagnosed during pregnancy
Guia Vannucchi, Michela Perrino, Stefania Rossi, Carla Colombo, Leonardo Vicentini, Davide Dazzi, Paolo Beck-Peccoz, Laura Fugazzola
European Journal of Endocrinology, 2010
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A
Klaus-Martin Schulte, Andreas Machens, Laura Fugazzola, Alan McGregor, Salvador Diaz-Cano, Louise Izatt, Simon Aylwin, Nadia Talat, Paolo Beck-Peccoz, Henning Dralle
Journal of Clinical Endocrinology and Metabolism, 2010
Thyroid Peroxidase Deficiency and Total Iodide Organification Defect
Laura Fugazzola
Comprehensive Handbook of Iodine, 2009
Functional characterization of wild-type and mutated pendrin (SLC26A4), the anion transporter involved in Pendred syndrome
Silvia Dossena, Simona Rodighiero, Valeria Vezzoli, Charity Nofziger, Elisabetta Salvioni, Marta Boccazzi, Elisabeth Grabmayer, Guido Bottà, Giuliano Meyer, Laura Fugazzola, Paolo Beck-Peccoz, Markus Paulmichl
Journal of Molecular Endocrinology, 2009
Outcome predictors and impact of central node dissection and radiometabolic treatments in papillary thyroid cancers ≤2 cm
Michela Perrino, Guia Vannucchi, Leonardo Vicentini, Gianmaria Cantoni, Davide Dazzi, Carla Colombo, Marcello Rodari, Arturo Chiti, Paolo Beck-Peccoz, Laura Fugazzola
Endocrine Related Cancer, 2009
Thyroid Peroxidase Deficiency and Total Iodide Organification Defect
Laura Fugazzola
Comprehensive Handbook of Iodine Nutritional Biochemical Pathological and Therapeutic Aspects, 2009
Absence of sonic hedgehog (Shh) germline mutations in patients with thyroid dysgenesis
Marina Muzza, Luca Persani, Tiziana de Filippis, Roberto Gastaldi, Maria Cristina Vigone, Davide Sala, Giovanna Weber, Renata Lorini, Paolo Beck‐Peccoz, Laura Fugazzola
Clinical Endocrinology, 2008
Fetal cell microchimerism in papillary thyroid cancer: A possible role in tumor damage and tissue repair
Valentina Cirello, Maria Paola Recalcati, Marina Muzza, Stefania Rossi, Michela Perrino, Leonardo Vicentini, Paolo Beck-Peccoz, Palma Finelli, Laura Fugazzola
Cancer Research, 2008
PKC-ε-dependent cytosol-to-membrane translocation of pendrin in rat thyroid PC C13 cells
A. Muscella, S. Marsigliante, T. Verri, L. Urso, C. Dimitri, G. Bottà, M. Paulmichl, P. Beck‐Peccoz, L. Fugazzola, C. Storelli
Journal of Cellular Physiology, 2008
RET genotypes in sporadic medullary thyroid cancer: Studies in a large Italian series
Laura Fugazzola, Marina Muzza, Caterina Mian, Daniela Cordella, Susi Barollo, Luisella Alberti, Valentina Cirello, Davide Dazzi, Maria Elisa Girelli, Giuseppe Opocher, Paolo Beck‐Peccoz, Luca Persani
Clinical Endocrinology, 2008
Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism
Ilaria Zamproni, Helmut Grasberger, Francesca Cortinovis, Maria Cristina Vigone, Giuseppe Chiumello, Stefano Mora, Kazumichi Onigata, Laura Fugazzola, Samuel Refetoff, Luca Persani, Giovanna Weber
Journal of Clinical Endocrinology and Metabolism, 2008
Expanding use of recombinant hTSH
L. Fugazzola
Annales D Endocrinologie, 2007
High phenotypic intrafamilial variability in patients with Pendred syndrome and novel duplication in the SLC26A4 gene: Clinical characterization and functional studies of the mutated SLC26A4 protein
Laura Fugazzola, Valentina Cirello, Silvia Dossena, Simona Rodighiero, Marina Muzza, Pierangela Castorina, Faustina Lalatta, Umberto Ambrosetti, Paolo Beck-Peccoz, Guido Bottà, Markus Paulmichl
European Journal of Endocrinology, 2007
Thyroid scintigraphy and perchlorate test after recombinant human TSH: A new tool for the differential diagnosis of congenital hypothyroidism during infancy
Laura Fugazzola, Luca Persani, Guia Vannucchi, Marco Carletto, Deborah Mannavola, Maria Cristina Vigone, Francesca Cortinovis, Luciano Beccaria, Virgilio Longari, Giovanna Weber, Paolo Beck-Peccoz
European Journal of Nuclear Medicine and Molecular Imaging, 2007
Histopathological and molecular studies in patients with goiter and hypercalcitoninemia: Reactive or neoplastic C-cell hyperplasia?
Uberta Verga, Stefano Ferrero, Leonardo Vicentini, Tatiana Brambilla, Valentina Cirello, Marina Muzza, Paolo Beck-Peccoz, Laura Fugazzola
Endocrine Related Cancer, 2007
A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake
Deborah Mannavola, Paola Coco, Guia Vannucchi, Rossella Bertuelli, Marco Carletto, Paolo G. Casali, Paolo Beck-Peccoz, Laura Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2007
TGB deficiency: Description of two novel mutations associated with complete TBG deficiency and review of the literature
Deborah Mannavola, Guia Vannucchi, Laura Fugazzola, Valentina Cirello, Irene Campi, Giorgio Radetti, Luca Persani, Samuel Refetoff, Paolo Beck-Peccoz
Journal of Molecular Medicine, 2006
An in-frame complex germline mutation in the juxtamembrane intracellular domain causing RET activation in familial medullary thyroid carcinoma
Daniela Cordella, Marina Muzza, Luisella Alberti, Paolo Colombo, Pietro Travaglini, Paolo Beck-Peccoz, Laura Fugazzola, Luca Persani
Endocrine Related Cancer, 2006
Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: Data from a multicentric Italian study and review of the literature
L Fugazzola, E Puxeddu, N Avenia, C Romei, V Cirello, A Cavaliere, P Faviana, D Mannavola, S Moretti, S Rossi, M Sculli, V Bottici, P Beck-Peccoz, F Pacini, A Pinchera, F Santeusanio, R Elisei
Endocrine Related Cancer, 2006
Fast fluorometric method for measuring pendrin (SLC26A4) Cl - /I - transport activity
Silvia Dossena, Simona Rodighiero, Valeria Vezzoli, Claudia Bazzini, Chiara Sironi, Giuliano Meyer, Johannes Fürst, Markus Ritter, Maria L. Garavaglia, Laura Fugazzola, Luca Persani, Patrick Zorowka, Carlo Storelli, Paolo Beck-Peccoz, Guido Bottà, Markus Paulmichl
Cellular Physiology and Biochemistry, 2006
Functional characterization of wild-type and a mutated form of SLC26A4 identified in a patient with pendred syndrome
Silvia Dossena, Valeria Vezzoli, Nadia Cerutti, Claudia Bazzini, Marisa Tosco, Chiara Sironi, Simona Rodighiero, Giuliano Meyer, Umberto Fascio, Johannes Fürst, Markus Ritter, Laura Fugazzola, Luca Persani, Patrick Zorowka, Carlo Storelli, Paolo Beck- Peccoz, Guido Bottà, Markus Paulmichl
Cellular Physiology and Biochemistry, 2006
The expression of wild-type pendrin (SLC26A4) in human embryonic kidney (HEK 293 Phoenix) cells lead to the activation of cationic currents
Silvia Dossena, Antonella Maccagni, Valeria Vezzoli, Claudia Bazzini, Maria Lisa Garavaglia, Giuliano Meyer, Johannes Fürst, Markus Ritter, Laura Fugazzola, Luca Persani, Patrick Zorowka, Carlo Storelli, Paolo Beck-Peccoz, Guido Bottà, Markus Paulmichl
European Journal of Endocrinology, 2005
Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene
Maria Grazia Borrello, Luisella Alberti, Andrew Fischer, Debora Degl'Innocenti, Cristina Ferrario, Manuela Gariboldi, Federica Marchesi, Paola Allavena, Angela Greco, Paola Collini, Silvana Pilotti, Giuliana Cassinelli, Paola Bressan, Laura Fugazzola, Alberto Mantovani, Marco A. Pierotti
Proceedings of the National Academy of Sciences of the United States of America, 2005
Total iodide organification defect: Clinical and molecular characterization of an Italian family
Laura Fugazzola, Deborah Mannavola, Maria Cristina Vigone, Valentina Cirello, Giovanna Weber, Paolo Beck-Peccoz, Luca Persani
Thyroid, 2005
Radioiodine treatment of non-toxic multinodular goitre: Effects of combination with lithium
Guia Vannucchi, Arturo Chiti, Deborah Mannavola, Davide Dazzi, Marcello Rodari, Sara Tadayyon, Paolo Beck-Peccoz, Laura Fugazzola
European Journal of Nuclear Medicine and Molecular Imaging, 2005
Medullary and papillary carcinoma of the thyroid gland occurring as a collision tumour: Report of three cases with molecular analysis and review of the literature
S Rossi
Endocrine Related Cancer, 2005
Different response to chronic somatostatin analogues in patients with central hyperthyroidism
Deborah Mannavola, Luca Persani, Guia Vannucchi, Maddalena Zanardelli, Laura Fugazzola, Uberta Verga, Marco Facchetti, Paolo Beck‐Peccoz
Clinical Endocrinology, 2005
Persistent mild hypothyroidism associated with novel sequence variants of the DUOX2 gene in two siblings.
Maria Cristina Vigone, Laura Fugazzola, Ilaria Zamproni, Arianna Passoni, Stefania Di Candia, Giuseppe Chiumello, Luca Persani, Giovanna Weber
Human Mutation, 2005
BRAF mutations in an Italian cohort of thyroid cancers
Laura Fugazzola, Deborah Mannavola, Valentina Cirello, Guia Vannucchi, Marina Muzza, Leonardo Vicentini, Paolo Beck‐Peccoz
Clinical Endocrinology, 2004
Recombinant human TSH testing is a valuable tool for differential diagnosis of congenital hypothyroidism during L-thyroxine replacement
Laura Fugazzola, Luca Persani, Deborah Mannavola, Eugenio Reschini, Guia Vannucchi, Giovanna Weber, Paolo Beck‐Peccoz
Clinical Endocrinology, 2003
Frequent association between MEN 2A and cutaneous lichen amyloidosis
Uberta Verga, Laura Fugazzola, Stefano Cambiaghi, Chiara Pritelli, Elvio Alessi, Donatella Cortelazzi, Emanuela Gangi, Paolo Beck‐Peccoz
Clinical Endocrinology, 2003
Monoallelic expression of mutant thyroid peroxidase allele causing total iodide organification defect
L. Fugazzola, N. Cerutti, D. Mannavola, G. Vannucchi, C. Fallini, L. Persani, P. Beck-Peccoz
Journal of Clinical Endocrinology and Metabolism, 2003
Erratum: Multigenerational familial medullary thyroid cancer (FMTC): Evidence for FMTC phenocopies and association with papillary thyroid cancer (Clinical Endocrinology 56 (53-63))
L. Fugazzola, N. Cerutti, D. Mannavola, G. Ghilardi, L. Alberti, R. Romoli, P. Beck‐Peccoz
Clinical Endocrinology, 2002
Multigenerational familial medullary thyroid cancer (FMTC): Evidence for FMTC phenocopies and association with papillary thyroid cancer
L. Fugazzola, N. Cerutti, D. Mannavola, G. Ghilardi, L. Alberti, R. Romoli, P. Beck‐Peccoz
Clinical Endocrinology, 2002
MEN1 gene mutations are a rare event in patients with sporadic neuroendocrine tumors
C Asteria, M Anagni, L Fugazzola, G Faglia, P Vezzadini, P Beck-Peccoz
European Journal of Internal Medicine, 2002
Genetic analyses and evaluation of peripheral parameters of thyroid hormone action for the differential diagnosis of RTH. A novel heterozygous missense mutation (M334T) discovered
D. Mannavola, G. Vannucchi, L. Fugazzola, N. Cerutti, L. Persani, Paolo Beck-Peccoz
Journal of Endocrinological Investigation, 2002
Differential diagnosis between Pendred and pseudo-Pendred syndromes: Clinical, radiologic, and molecular studies
Laura Fugazzola, Nadia Cerutti, Deborah Mannavola, Antonino Crinò, Alessandra Cassio, Pietro Gasparoni, Guia Vannucchi, Paolo Beck-Peccoz
Pediatric Research, 2002
Highly sensitive serum thyroglobulin and circulating thyroglobulin mRNA evaluations in the management of patients with differentiated thyroid cancer in apparent remission
Laura Fugazzola, Alessandra Mihalich, Luca Persani, Nadia Cerutti, Michela Reina, Marco Bonomi, Emanuela Ponti, Deborah Mannavola, Enza Giammona, Guia Vannucchi, Anna Maria di Blasio, Paolo Beck-Peccoz
Journal of Clinical Endocrinology and Metabolism, 2002
The role of pendrin in iodide regulation
L. Fugazzola, N. Cerutti, D. Mannavola, G. Vannucchi, P. Beck-Peccoz
Experimental and Clinical Endocrinology and Diabetes, 2001
Gene symbol: THRB: Disease: Thyroid hormone resistance
Human Genetics, 2001
Molecular analysis of the Pendred's syndrome gene and magnetic resonance imaging studies of the inner ear are essential for the diagnosis of true Pendred's syndrome
L. Fugazzola
Journal of Clinical Endocrinology and Metabolism, 2000
Thyrotropic adenomas treated with lanreotide
Journal of Endocrinological Investigation, 1997
Comparison of the breakpoint regions of ELE1 and RET genes involved in the generation of RET/PTC3 oncogene in sporadic and in radiation-associated papillary thyroid carcinomas
Italia Bongarzone, Marta G. Butti, Laura Fugazzola, Furio Pacini, Aldo Pinchera, Tatiana V. Vorontsova, Eugene P. Demidchik, Marco A. Pierotti
Genomics, 1997
Molecular and biochemical analysis of RET/PTC4, a novel oncogenic rearrangement between RET and ELE1 genes, in a post-Chernobyl papillary thyroid cancer
Oncogene, 1996
Age-related activation of the tyrosine kinase receptor protooncogenes RET and NTRK1 in papillary thyroid carcinoma
I. Bongarzone
Journal of Clinical Endocrinology and Metabolism, 1996
Oncogenic Rearrangements of the RET Proto-Oncogene in Papillary Thyroid Carcinomas from Children Exposed to the Chernobyl Nuclear Accident
Cancer Research, 1995
Post-surgical follow-up of differentiated thyroid cancer
F. Pacini, R. Elisei, L. Fugazzola, F. Cetani, C. Romei, F. Mancusi, A. Pinchera
Journal of Endocrinological Investigation, 1995
Routine measurement of serum calcitonin in nodular thyroid diseases allows the preoperative diagnosis of unsuspected sporadic medullary thyroid carcinoma
F. Pacini
Journal of Clinical Endocrinology and Metabolism, 1994
Expression of thyrotropin receptor (TSH-R), thyroglobulin, thyroperoxidase, and calcitonin messenger ribonucleic acids in thyroid carcinomas: Evidence of TSH-R gene transcript in medullary histotype
R. Elisei
Journal of Clinical Endocrinology and Metabolism, 1994
Expression of p21 ras protein as a prognostic factor in papillary thyroid cancer
Fulvio Basolo, Aldo Pinchera, Laura Fugazzola, Gabriella Fontanini, Rossella Elisei, Cristina Romei, Furio Pacini
European Journal of Cancer, 1994
Serum soluble interleukin 2 (IL-2) receptor (sIL-2R) in differentiated thyroid carcinoma
S. Mariotti, G. Barbesino, P. Caturegli, M. Marinò, L. Manetti, L. Fugazzola, F. Pacini, A. Pinchera
Journal of Endocrinological Investigation, 1994
Testicular function in patients with differentiated thyroid carcinoma treated with radioiodine
Journal of Nuclear Medicine, 1994
Disappearance rate of serum calcitonin after total thyroidectomy for medullary thyroid carcinoma
L. Fugazzola, A. Pinchera, F. Luchetti, P. Iacconi, P. Miccoli, C. Romei, M. Puccini, F. Pacini
International Journal of Biological Markers, 1994
Multiple endocrine neoplasia type 2A and cutaneous lichen amyloidosis: Description of a new family
Furio Pacini, L. Fugazzola, G. Bevilacqua, P. Viacava, V. Nardini, E. Martino
Journal of Endocrinological Investigation, 1993
Markers of cell proliferation as prognostic factors in differentiated thyroid cancer
F BASOLO, L FUGAZZOLA, G FONTANINI, R ELISEI, S PEPE, G BEVILACQUA, A PINCHERA, F PACINI
International Journal of Oncology, 1993
Expression of calcitonin gene-related peptide in medullary thyroid cancer
F. Pacini, L. Fugazzola, F. Basolo, R. Elisei, A. Pinchera
Journal of Endocrinological Investigation, 1992
Detection of thyroglobulin in fine needle aspirates of nonthyroidal neck masses: A clue to the diagnosis of metastatic differentiated thyroid cancer
Journal of Clinical Endocrinology and Metabolism, 1992
Medullary thyroid cancer. An immunohistochemical and humoral study using six separate antigens
Furio Pacini, Fulvio Basolo, Rossella Elisei, Laura Fugazzola, Arianna Cola, Aldo Pinchera
American Journal of Clinical Pathology, 1991

Laura Fugazzola

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