Egidio Ugo D'Angelo

Scopus Publications

Targeted antisense oligonucleotide treatment rescues developmental alterations in spinal muscular atrophy organoids
Irene Faravelli, Paola Rinchetti, Monica Tambalo, Illia Simutin, Lisa Mapelli, Sara Mancinelli, Matteo Miotto, Mafalda Rizzuti, Andrea D’Angelo, Chiara Cordiglieri, Giulia Forotti, Clelia Peano, Paolo Kunderfranco, Luca Calandriello, Giacomo P. Comi, Elvezia Paraboschi, Eleonora Pali, Francesca Beatrice, Egidio D’Angelo, Serge Przedborski, Monica Nizzardo, Simona Lodato, Stefania Corti
Nature Communications, 2026
Spinal muscular atrophy (SMA) is a severe neurological disease caused by mutations in the SMN1 gene, characterized by early onset and degeneration of lower motor neurons. Understanding early neurodevelopmental defects in SMA is crucial for optimizing therapeutic interventions. Using spinal cord and cerebral organoids generated from multiple SMA type 1 male donors, we revealed widespread disease mechanisms beyond motor neuron degeneration. Single-cell transcriptomics uncovered pervasive alterations across neural populations, from progenitors to neurons, demonstrating SMN-dependent dysregulation of neuronal differentiation programs. Multi-electrode array (MEA) analysis identified consistent hyperexcitability in both spinal and brain organoids, establishing altered electrical properties as a central nervous system-wide feature of pathogenesis. Early administration of an optimized antisense oligonucleotide (ASO) that increased SMN levels rescued morphological and functional deficits in spinal cord organoids across different genetic backgrounds. Importantly, this early intervention precisely corrected aberrant splicing in here identified SMN1 targets enriched at critical nodes of neuronal differentiation. Our findings demonstrate that early developmental defects are core features of SMA pathogenesis that can be prevented by timely therapeutic intervention, providing insights for optimizing treatment strategies.
The Sense of Smell (SoS) Atlas: Its Creation and First Application to Investigate COVID-19 Related Anosmia With a Comprehensive Quantitative MRI Protocol
Marta Gaviraghi, Eleonora Lupi, Elena Grosso, Andrea Fusari, Mattia Baiguera, Anita Monteverdi, Marco Battiston, Francesco Grussu, Baris Kanber, Ferran Prados Carrasco, Rebecca S. Samson, Janine Makaronidis, Marios C. Yiannakas, Michael S. Zandi, Rachel L. Batterham, Egidio D'Angelo, Fulvia Palesi, Claudia A. M. Gandini Wheeler‐Kingshott
Journal of Magnetic Resonance Imaging, 2026
BackgroundThe loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.PurposeTo develop the sense of smell (SoS) atlas, including gray matter regions and white matter tracts of the olfactory circuit, to investigate the underpinnings of COVID‐19 related anosmia.Study TypeRetrospective.SubjectsFor the SoS atlas, high‐resolution tractograms of 10 healthy controls (HC) of the Human Connectome Project (7 females, 22–35 years) were used. The SoS atlas was applied to 8 subjects with persistent anosmia following COVID‐19 (COVID‐P, 7 females, 52 ± 12 years), 19 subjects that recovered from COVID‐19 anosmia (COVID‐R, 14 females, 38 ± 13 years), and 17 HC (8 females, 39 ± 12 years).Field Strength/Sequence3 T, 3D inversion recovery, 3D fast field echo, and spin‐echo echo‐planar imaging sequences.AssessmentTo create the SoS atlas, regions were identified and tracts were extracted via tractography following biological constraints. MRI metrics sensitive to alterations in neuroinflammation, axonal degeneration, myelin and macromolecular density, and iron were analyzed.Statistical TestsRegion‐based analysis (p‐value < 0.05, false discovery rate (FDR) corrected) and voxel‐based analysis (p‐value < 0.001 uncorrected, FDR‐corrected cluster extent = 5 voxels) were performed on 15 multisequence‐MRI metrics between the three groups.ResultsThe SoS atlas consisted of 35 regions and, after anatomical curation, the initial 506 tracts were refined to 78. Compared to HC, COVID‐P presented alterations in neuroinflammation‐related (mean: 41% of total alterations) and axonal degeneration‐related (31%) MRI metrics, while COVID‐R presented alterations of myelin‐related metrics (68%). COVID‐P alterations mainly affected the hindbrain (56%), while COVID‐R the hindbrain (39%).Data ConclusionA novel tool, the SoS atlas, was developed to study the olfactory system and applied in combination with multisequence‐MRI metrics to investigate the mechanisms of COVID‐19 related anosmia.Evidence Level3.Technical EfficacyStage 1.
Editorial: Multiscale brain modelling
Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2026
Addressing the multiscale brain organization is fundamental not only to understand its inherent mechanisms of function but also to answer neuropathological questions and promote the development of new technologies for AI and health. A review on the issue is presented here in the paper by Krejcar and Namazi (2025) and additional information can be found in D'Angelo and Jirsa (2022) and Wang et al. (2024). The Authors have then covered two main areas of research: theoretical models of neuronal excitability, network oscillations, and brain activity, and models applied to the study of Alzheimer's disease. Galinsky and Frank (2025) address the wave nature of the action potentials proposing an alternative framework to the standard Hodgkin-Huxley model for the action potential in axons. This is based on the Author's theory of electric field wave propagation in anisotropic and inhomogeneous brain tissues and addresses the limitations of the Hodgkin-Huxley model, including its inability to explain extracellular spiking, efficient brain synchronization, saltatory conduction along myelinated axons, and various other observed coherent macroscopic brain electrical phenomena. Pieramico et al. (2025) show how Hidden Markov Models can be used to analyze time series of neural activity. The study demonstrates that Time-Delay Embedded Hidden Markov Models performs better than Gaussian models in accurately detecting brain states from synthetic phase-coupled interaction data. Finally, Ghosh et al. (2025) present general trainable networks of Hopf oscillators to model high-dimensional electroencephalogram (EEG) signals across different sleep stages. The model, once embedded with a hidden layer, can faithfully predict the empirical EEG representing a step toward constructing a large-scale, biologically inspired model of brain dynamics.Two papers address Alzheimer disease. Fadel et al. (2025) present a model of functional connectivity changes with learning and memory in a mouse model based on data obtained from mutant mice. The APP/PS1 mice showed a pattern of hyperconnectivity, including the Default Mode Network, after learning. Modeling revealed functional connections that support learning and memory performance. These models show potential for early disease detection by identifying connectivity patterns associated with cognitive decline and may provide a means to understand how FC translates into learning and memory performance. Moravveji et al. (2025) show a sensitivity analysis of a mathematical model of Alzheimer's disease progression to unveil causal pathways. The study presents the first local sensitivity analysis of a multiscale ODE-based model of Alzheimer's Disease (AD) and captures the multifactorial nature of AD incorporating neuronal, pathological, and inflammatory processes at the nano, micro and macro scales. This detailed framework enables realistic simulation of disease progression and identification of key biological parameters that influence system behavior. This analysis identifies the key drivers of disease progression across patient profiles, providing insight into targeted therapeutic strategies.
Region-specific mean field models enhance simulations of local and global brain dynamics
Roberta Maria Lorenzi, Fulvia Palesi, Claudia Casellato, Claudia A. M. Gandini Wheeler-Kingshott, Egidio D’Angelo
Npj Systems Biology and Applications, 2025
Brain dynamics can be simulated using virtual brain models, in which a standard mathematical representation of oscillatory activity is usually adopted for all cortical and subcortical regions. However, some brain regions have specific microcircuit properties that are not recapitulated by standard oscillators. Moreover, magnetic resonance imaging (MRI)-based connectomes may not be able to capture local circuit connectivity. Region-specific models incorporating computational properties of local neurons and microcircuits have recently been generated using the mean field (MF) approach and proposed to impact large-scale brain dynamics. Here, we have used a MF of the cerebellar cortex to generate a mesoscopic model of the whole cerebellum featuring a prewired connectivity of multiple cerebellar cortical areas with deep cerebellar nuclei. This multi-node cerebellar MF was then used to substitute the corresponding standard oscillators and build up a cerebellar mean field virtual brain (cMF-TVB) for a group of healthy human subjects. Simulations revealed that electrophysiological and fMRI signals generated by the cMF-TVB significantly improved the fitness of local and global dynamics with respect to a homogeneous model made solely of standard oscillators. The cMF-TVB reproduced the rhythmic oscillations and coherence typical of the cerebellar circuit and allowed to correlate electrophysiological and functional MRI signals to specific neuronal populations. In aggregate, region-specific models based on MF and pre-wired circuit connectivity can significantly improve virtual brain simulations, fostering the generation of effective brain digital twins that could be used for physiological studies and clinical applications.
Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells
Eleonora Pali, Stefano Masoli, Danila Di Domenico, Teresa Sorbo, Francesca Prestori, Egidio D’Angelo
Communications Biology, 2025
Cerebellar Golgi cells (GoCs), segregate parallel fiber (pf), and mossy fiber (mf) inputs on apical and basal dendrites. Computational modeling predicted that this anatomical arrangement, coupled with a specific ionic channel localization, could be instrumental to drive STDP at mf-GoC synapses. Here, we test this hypothesis with GoC patch-clamp recordings in acute mouse cerebellar slices. Repeated mf-pf pairing on the theta-band within a ± 50 ms time window induces anti-symmetric Hebbian-STDP, with spike-timing long-term potentiation or depression (st-LTP or st-LTD) occurring when action potentials (APs) elicited by pf stimulation follow or precede the activation of mf synapses, respectively. Mf-GoC STDP induction requires AP backpropagation from apical to basal dendrites, NMDA receptor activation at mf-GoC synapses, and intracellular calcium changes. Importantly, STDP is inverted by inhibitory control. Thus, experimental evidence confirms and extends model predictions suggesting that GoC STDP can bind molecular layer to granular layer activity, regulating cerebellar computation and learning.
Cerebellar basket cell filtering of Purkinje cell responses elicited by low frequency parallel fibre transmission
Stefano Masoli, Martina Francesca Rizza, Teresa Soda, Diana Sánchez-Ponce, Alberto Munoz, et al.
Scientific Reports, 2025
Basket cells (BC) are inhibitory interneurons of the cerebellar molecular layer (ML) forming peri-somatic synapses on Purkinje cells (PC). BC physiological and computational properties remained poorly understood and not clearly differentiated from those of stellate cells (SC). We identified BCs in acute mouse cerebellar slices and measured their intrinsic excitability and synaptic responsiveness. BCs and SCs were similar in some respects, although BCs showed stronger and faster synaptic excitation in response to parallel fibre (pf) bursts. The analysis of BC inhibition of PCs was extended over a broad parameter space using accurate multi-compartmental computational models. During pf bursts, the BC reduced the PC response at low-frequency, while SCs did it at high-frequency. BC filtering was explained by the engagement of HCN1 channels, which activated slowly during low-frequency BC-PC GABAergic transmission. The increase of input conductance caused by HCN1 channels in the PC soma, by shunting excitatory currents elicited by pfs and travelling toward the axon initial segment (AIS), reduced the PC output frequency. These simulations predict that BC and SC operate in tandem, setting the frequency band of PC transmission through the regulation of PC frequency/response curves.
A Computational Model of the Respiratory CPG for the Artificial Control of Breathing
Lorenzo De Toni, Federica Perricone, Lorenzo Tartarini, Giulia Maria Boiani, Stefano Cattini, Luigi Rovati, Dimitri Rodarie, Egidio D’Angelo, Jonathan Mapelli, Daniela Gandolfi
Bioengineering, 2025
The human respiratory Central Pattern Generator (CPG) is a complex and tightly regulated network of neurons responsible for the automatic rhythm of breathing. Among the brain nuclei involved in respiratory control, excitatory neurons within the PreBotzinger Complex (PreBötC) are both necessary and sufficient for generating this rhythmic activity. Although several models of the PreBötC circuit have been proposed, a comprehensive analysis of network behavior in response to physiologically relevant external inputs remains limited. In this study, we present a computational model of the PreBötC consisting of 1000 excitatory neurons, divided into two functional subgroups: the rhythm-generating population and the pattern-forming population. To enable real-time closed-loop simulations, we employed parallelized multi-process computing to accelerate network simulation. The network, composed of asynchronous neurons, could produce bursting activity at a eupneic breathing frequency of 0.22 Hz, which could also reproduce the rapid and stable chemoreception of breathing activated in response to hypercapnia. Additionally, it successfully replicated rapid and stable respiratory responses to elevated carbon dioxide levels (hypercapnia), mediated through simulated chemoreception. External inputs from a carbon dioxide sensor were used to modulate the network activity, allowing the implementation of a real-time respiratory control system. These results demonstrate that a network of asynchronous, non-bursting neurons can emulate the behavior of the respiratory CPG and its modulation by external stimuli. The proposed model represents a step toward developing a closed-loop controller for breathing regulation.
Enhanced electrophysiological recordings in acute brain slices, spheroids, and organoids using 3D high-density multielectrode arrays
Lisa Mapelli, Danila Di Domenico, Giacomo Sciacca, Francesco Mainardi, Alessandra Ottaviani, Anita Monteverdi, Mariateresa Tedesco, Chiara Rosa Battaglia, Simona Tritto, Mauro Gandolfo, Kilian Imfeld, Stefanie Kiderlen, Lukas Krainer, Chiara Cervetto, Manuela Marcoli, Anson Sing, Jimena Andersen, Fikri Birey, Steven A. Sloan, Alessandro Maccione, Egidio D'Angelo
Plos One, 2025
Recent advances in three-dimensional (3D) biological brain models in vitro and ex vivo are creating new opportunities to understand the complexity of neural networks but pose the technological challenge of obtaining high-throughput recordings of electrical activity from multiple sites in 3D at high spatiotemporal resolution. This cannot be achieved using planar multi-electrode arrays (MEAs), which contact just one side of the neural structure. Moreover, the specimen adhesion to planar MEAs limits fluid perfusion along with tissue viability and drug application. Here, the efficiency of the tissue-sensor interface provided by advanced 3D high-density (HD)-MEA technology was evaluated in acute brain slices, spheroids, and organoids obtained from different brain regions. The 3D HD-MEA microneedles reached the inner layers of samples without damaging network integrity and the microchannel network between microneedles improved tissue vitality and chemical compound diffusion. In acute cortico-hippocampal and cerebellar slices, signal recording and stimulation efficiency proved higher with the 3D HD-MEA than with a planar MEA improving the characterization of network activity and functional connectivity. The 3D HD-MEA also resolved the challenge of recording from brain spheroids as well as cortical and spinal organoids. Our results show that 3D HD-MEA technology represents a valuable tool to address the complex spatiotemporal organization of activity in brain microcircuits, making it possible to investigate 3D biological models.
Cerebellar control over inter-regional excitatory/inhibitory dynamics discriminates execution from observation of an action
Roberta Maria Lorenzi, Gökçe Korkmaz, Adnan A. S. Alahmadi, Anita Monteverdi, Letizia Casiraghi, Egidio D’Angelo, Fulvia Palesi, Claudia A. M. Gandini Wheeler-Kingshott
Cerebellum, 2025
The motor learning theory anticipates that cerebro-cerebellar loops perform sensorimotor prediction, thereby regulating motor control during action execution (AE) and observation (AO), but the causal interaction between the cerebellum and cerebral cortex remains unclear. Therefore, our aim was to understand what triggers neuronal activity between brain areas engaged in a visuo-motor task that involves cortico-cerebellar interactions, organised in loops. We used Dynamic Causal Modelling (DCM) to study functional MRI (fMRI) data obtained in healthy participants during a squeeze-ball task in either execution or observation conditions. In both cases, active regions included bilateral primary visual cortex (V1), left primary motor cortex (M1), supplementary motor and premotor cortex (SMAPMC), cingulate cortex (CC), superior parietal lobule (SPL), and right cerebellum (CRBL). Networks supporting executing or observing an action showed the same effective connectivity, with pathways between regions wired in closed loops. However, the cerebellar communication towards the cerebral cortex switched from excitatory in execution to inhibitory in observation. Moreover, when executing the action signal modulation was non-linear from SMAPMC to CRBL and within the CRBL self-connection, supporting that the CRBL elaborates motor plans received from SMAPMC. Thus, the need for motor planning and the presence of a sensorimotor feedback in action execution discriminate the modality of forward control operated by the CRBL. Interestingly, this study also showed that the CRBL differentially controls the excitatory/inhibitory dynamics of inter-regional effective connectivity, depending on its functional engagement. These findings are fundamental for understanding brain dynamics in health and disease and for designing artificial sensorimotor controllers.
Linking cellular-level phenomena to brain architecture: the case of spiking cerebellar controllers
Egidio D’Angelo, Alberto Antonietti, Alice Geminiani, Benedetta Gambosi, Cristiano Alessandro, Emiliano Buttarazzi, Alessandra Pedrocchi, Claudia Casellato
Neural Networks, 2025
Linking cellular-level phenomena to brain architecture and behavior is a holy grail for theoretical and computational neuroscience. Advances in neuroinformatics have recently allowed scientists to embed spiking neural networks of the cerebellum with realistic neuron models and multiple synaptic plasticity rules into sensorimotor controllers. By minimizing the distance (error) between the desired and the actual sensory state, and exploiting the sensory prediction, the cerebellar network acquires knowledge about the body-environment interaction and generates corrective signals. In doing so, the cerebellum implements a generalized computational algorithm, allowing it "to learn to predict the timing between correlated events" in a rich set of behavioral contexts. Plastic changes evolve trial by trial and are distributed over multiple synapses, regulating the timing of neuronal discharge and fine-tuning high-speed movements on the millisecond timescale. Thus, spiking cerebellar built-in controllers, among various computational approaches to studying cerebellar function, are helping to reveal the cellular-level substrates of network learning and signal coding, opening new frontiers for predictive computing and autonomous learning in robots.
The Cerebellar Role in Emotions at a Turning Point: Bibliometric Analysis and Collaboration Networks
Dianela A. Osorio-Becerra, Egidio D’Angelo, Claudia Casellato
Cerebellum, 2025
Women Versus Men: Comparative Analysis of Physical Activity and Mobile Phone Usage on Cognitive Performance
Chaitanya Nutakki, Giovanni Naldi, Egidio D'Angelo, Shyam Diwakar
2025 Gender and Technology Conference Gtc 2025, 2025
The spiny relationship between parallel fibers, climbing fibers, and Purkinje cells
Stefano Masoli, Martina Francesca Rizza, Francesco Moccia, Egidio D’Angelo
Frontiers in Physiology, 2025
An Equivalent Single Spiking Neuron Model of the Working Memory
Navya Ajith, Arathi Rajendran, Giovanni Naldi, Egidio D'Angelo, Shyam Diwakar
2025 International Conference on Cognitive Computing in Engineering Communications Sciences and Biomedical Health Informatics Ic3ecsbhi 2025, 2025
Editorial: Paradigm shifts and innovations in cellular neuroscience
Enrico Cherubini, Arianna Maffei, Egidio D'Angelo, Dirk M. Hermann, Marie-Ève Tremblay, et al.
Frontiers in Cellular Neuroscience, 2025
Human Purkinje cells outperform mouse Purkinje cells in dendritic complexity and computational capacity
Stefano Masoli, Diana Sanchez-Ponce, Nora Vrieler, Karin Abu-Haya, Vitaly Lerner, Tal Shahar, Hermina Nedelescu, Martina Francesca Rizza, Ruth Benavides-Piccione, Javier DeFelipe, Yosef Yarom, Alberto Munoz, Egidio D’Angelo
Communications Biology, 2024
Author Correction: Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA (Scientific Reports, (2023), 13, 1, (17355), 10.1038/s41598-023-43706-6)
Silvia De Francesco, Claudio Crema, Damiano Archetti, Cristina Muscio, Robert I. Reid, Anna Nigri, Maria Grazia Bruzzone, Fabrizio Tagliavini, Raffaele Lodi, Egidio D’Angelo, Brad Boeve, Kejal Kantarci, Michael Firbank, John-Paul Taylor, Pietro Tiraboschi, Alberto Redolfi, Maria Grazia Bruzzone, Pietro Tiraboschi, Claudia A. M. Gandini Wheeler-Kingshott, Michela Tosetti, Gianluigi Forloni, Alberto Redolfi, Egidio D’Angelo, Fabrizio Tagliavini, Raffaele Lodi, Raffaele Agati, Marco Aiello, Elisa Alberici, Carmelo Amato, Domenico Aquino, Filippo Arrigoni, Francesca Baglio, Laura Biagi, Lilla Bonanno, Paolo Bosco, Francesca Bottino, Marco Bozzali, Nicola Canessa, Chiara Carducci, Irene Carne, Lorenzo Carnevale, Antonella Castellano, Carlo Cavaliere, Mattia Colnaghi, Valeria Elisa Contarino, Giorgio Conte, Mauro Costagli, Greta Demichelis, Silvia De Francesco, Andrea Falini, Stefania Ferraro, Giulio Ferrazzi, Lorenzo Figà Talamanca, Cira Fundarò, Simona Gaudino, Francesco Ghielmetti, Ruben Gianeri, Giovanni Giulietti, Marco Grimaldi, Antonella Iadanza, Matilde Inglese, Maria Marcella Laganà, Marta Lancione, Fabrizio Levrero, Daniela Longo, Giulia Lucignani, Martina Lucignani, Maria Luisa Malosio, Vittorio Manzo, Silvia Marino, Jean Paul Medina, Edoardo Micotti, Claudia Morelli, Cristina Muscio, Antonio Napolitano, Anna Nigri, Francesco Padelli, Fulvia Palesi, Patrizia Pantano, Chiara Parrillo, Luigi Pavone, Denis Peruzzo, Nikolaos Petsas, Anna Pichiecchio, Alice Pirastru, Letterio S. Politi, Luca Roccatagliata, Elisa Rognone, Andrea Rossi, Maria Camilla Rossi-Espagnet, Claudia Ruvolo, Marco Salvatore, Giovanni Savini, Emanuela Tagliente, Claudia Testa, Caterina Tonon, Domenico Tortora, Fabio Maria Triulzi, and
Scientific Reports, 2024
A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations
Benedetta Gambosi, Francesco Jamal Sheiban, Marco Biasizzo, Alberto Antonietti, Egidio D’angelo, Alberto Mazzoni, Alessandra Pedrocchi
International Journal of Neural Systems, 2024
Understanding Cerebellar Input Stage through Computational and Plasticity Rules
Eleonora Pali, Egidio D’Angelo, Francesca Prestori
Biology, 2024
The coming decade of digital brain research: A vision for neuroscience at the intersection of technology and computing
Katrin Amunts, Markus Axer, Swati Banerjee, Lise Bitsch, Jan G. Bjaalie, et al.
Imaging Neuroscience, 2024
Mesoscale simulations predict the role of synergistic cerebellar plasticity during classical eyeblink conditioning
Alice Geminiani, Claudia Casellato, Henk-Jan Boele, Alessandra Pedrocchi, Chris I. De Zeeuw, Egidio D’Angelo
Plos Computational Biology, 2024
New clues for the role of cerebellum in schizophrenia and the associated cognitive impairment
Pawan Faris, Doris Pischedda, Fulvia Palesi, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2024
Multiscale modeling of neuronal dynamics in hippocampus CA1
Federico Tesler, Roberta Maria Lorenzi, Adam Ponzi, Claudia Casellato, Fulvia Palesi, Daniela Gandolfi, Claudia A. M. Gandini Wheeler Kingshott, Jonathan Mapelli, Egidio D'Angelo, Michele Migliore, Alain Destexhe
Frontiers in Computational Neuroscience, 2024
Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA
Silvia De Francesco, Claudio Crema, Damiano Archetti, Cristina Muscio, Robert I. Reid, Anna Nigri, Maria Grazia Bruzzone, Fabrizio Tagliavini, Raffaele Lodi, Egidio D’Angelo, Brad Boeve, Kejal Kantarci, Michael Firbank, John-Paul Taylor, Pietro Tiraboschi, Alberto Redolfi, Maria Grazia Bruzzone, Pietro Tiraboschi, Claudia A. M. Gandini Wheeler-Kingshott, Michela Tosetti, Gianluigi Forloni, Alberto Redolfi, Egidio D’Angelo, Fabrizio Tagliavini, Raffaele Lodi, Raffaele Agati, Marco Aiello, Elisa Alberici, Carmelo Amato, Domenico Aquino, Filippo Arrigoni, Francesca Baglio, Laura Biagi, Lilla Bonanno, Paolo Bosco, Francesca Bottino, Marco Bozzali, Nicola Canessa, Chiara Carducci, Irene Carne, Lorenzo Carnevale, Antonella Castellano, Carlo Cavaliere, Mattia Colnaghi, Valeria Elisa Contarino, Giorgio Conte, Mauro Costagli, Greta Demichelis, Silvia De Francesco, Andrea Falini, Stefania Ferraro, Giulio Ferrazzi, Lorenzo Figà Talamanca, Cira Fundarò, Simona Gaudino, Francesco Ghielmetti, Ruben Gianeri, Giovanni Giulietti, Marco Grimaldi, Antonella Iadanza, Matilde Inglese, Maria Marcella Laganà, Marta Lancione, Fabrizio Levrero, Daniela Longo, Giulia Lucignani, Martina Lucignani, Maria Luisa Malosio, Vittorio Manzo, Silvia Marino, Jean Paul Medina, Edoardo Micotti, Claudia Morelli, Cristina Muscio, Antonio Napolitano, Anna Nigri, Francesco Padelli, Fulvia Palesi, Patrizia Pantano, Chiara Parrillo, Luigi Pavone, Denis Peruzzo, Nikolaos Petsas, Anna Pichiecchio, Alice Pirastru, Letterio S. Politi, Luca Roccatagliata, Elisa Rognone, Andrea Rossi, Maria Camilla Rossi-Espagnet, Claudia Ruvolo, Marco Salvatore, Giovanni Savini, Emanuela Tagliente, Claudia Testa, Caterina Tonon, Domenico Tortora, Fabio Maria Triulzi, and
Scientific Reports, 2023
A multi-layer mean-field model of the cerebellum embedding microstructure and population-specific dynamics
Roberta Maria Lorenzi, Alice Geminiani, Yann Zerlaut, Marialaura De Grazia, Alain Destexhe, Claudia A. M. Gandini Wheeler-Kingshott, Fulvia Palesi, Claudia Casellato, Egidio D’Angelo
Plos Computational Biology, 2023
Parallel processing relies on a distributed, low-dimensional cortico-cerebellar architecture
Eli J. Müller, Fulvia Palesi, Kevin Y. Hou, Joshua Tan, Thomas Close, Claudia A. M. Gandini Wheeler-Kingschott, Egidio D’Angelo, Fernando Calamante, James M. Shine
Network Neuroscience, 2023
Italian, European, and international neuroinformatics efforts: An overview
Alberto Redolfi, Damiano Archetti, Silvia De Francesco, Claudio Crema, Fabrizio Tagliavini, Raffaele Lodi, Roberta Ghidoni, Claudia A. M. Gandini Wheeler‐Kingshott, Daniel C. Alexander, Egidio D'Angelo
European Journal of Neuroscience, 2023
Anisotropy and Frequency Dependence of Signal Propagation in the Cerebellar Circuit Revealed by High-Density Multielectrode Array Recordings
Anita Monteverdi, Danila Di Domenico, Egidio D’Angelo, Lisa Mapelli
Biomedicines, 2023
Aberrant olfactory network functional connectivity in people with olfactory dysfunction following COVID-19 infection: an exploratory, observational study
Jed Wingrove, Janine Makaronidis, Ferran Prados, Baris Kanber, Marios C. Yiannakas, Cormac Magee, Gloria Castellazzi, Louis Grandjean, Xavier Golay, Carmen Tur, Olga Ciccarelli, Egidio D'Angelo, Claudia A.M. Gandini Wheeler-Kingshott, Rachel L. Batterham
Eclinicalmedicine, 2023
Full-scale scaffold model of the human hippocampus CA1 area
Daniela Gandolfi, Jonathan Mapelli, Sergio M. G. Solinas, Paul Triebkorn, Egidio D’Angelo, Viktor Jirsa, Michele Migliore
Nature Computational Science, 2023
Distributed Plasticity in the Cerebellar Circuit
Egidio D’Angelo
Essentials of Cerebellum and Cerebellar Disorders A Primer for Graduate Students Second Edition, 2023
Granule Cells and Parallel Fibers
Egidio D’Angelo
Essentials of Cerebellum and Cerebellar Disorders A Primer for Graduate Students Second Edition, 2023
Editorial: Cerebellum-related learning and psychiatric diseases
Gen Ohtsuki, Taegon Kim, Peng Sun, Yongjun Chen, Egidio Ugo D'Angelo
Frontiers in Cellular Neuroscience, 2023
Variations on the theme: focus on cerebellum and emotional processing
Camilla Ciapponi, Yuhe Li, Dianela A. Osorio Becerra, Dimitri Rodarie, Claudia Casellato, Lisa Mapelli, Egidio D’Angelo
Frontiers in Systems Neuroscience, 2023
Computational Modelling of Glucocerebrosidase Signalling Pathways in Parkinson’s Disease
Hemalatha Sasidharakurup, Kasi Viswanadh, Divya M. Sasidharan, Anu Sasidharan, Arushi Tiwari, Devi Krishna, Giovanni Naldi, Egidio D’Angelo, Shyam Diwakar
Lecture Notes in Networks and Systems, 2023
Structural and connectivity parameters reveal spared connectivity in young patients with non-progressive compared to slow-progressive cerebellar ataxia
Silvia Maria Marchese, Fulvia Palesi, Anna Nigri, Maria Grazia Bruzzone, Chiara Pantaleoni, Claudia A. M. Gandini Wheeler-Kingshott, Stefano D’Arrigo, Egidio D’Angelo, Paolo Cavallari
Frontiers in Neurology, 2023
Myelin quantification in Magnetic Resonance Imaging
Convegno Nazionale Di Bioingegneria, 2023
Virtual brain simulations reveal network-specific parameters in neurodegenerative dementias
Anita Monteverdi, Fulvia Palesi, Michael Schirner, Francesca Argentino, Mariateresa Merante, Alberto Redolfi, Francesca Conca, Laura Mazzocchi, Stefano F. Cappa, Matteo Cotta Ramusino, Alfredo Costa, Anna Pichiecchio, Lisa M. Farina, Viktor Jirsa, Petra Ritter, Claudia A. M. Gandini Wheeler-Kingshott, Egidio D’Angelo
Frontiers in Aging Neuroscience, 2023
Long-Term Synaptic Plasticity Tunes the Gain of Information Channels through the Cerebellum Granular Layer
Jonathan Mapelli, Giulia Maria Boiani, Egidio D’Angelo, Albertino Bigiani, Daniela Gandolfi
Biomedicines, 2022
Model simulations unveil the structure-function-dynamics relationship of the cerebellar cortical microcircuit
Robin De Schepper, Alice Geminiani, Stefano Masoli, Martina Francesca Rizza, Alberto Antonietti, Claudia Casellato, Egidio D’Angelo
Communications Biology, 2022
A realistic morpho-anatomical connection strategy for modelling full-scale point-neuron microcircuits
Daniela Gandolfi, Jonathan Mapelli, Sergio Solinas, Robin De Schepper, Alice Geminiani, Claudia Casellato, Egidio D’Angelo, Michele Migliore
Scientific Reports, 2022
Author Correction: A realistic morpho-anatomical connection strategy for modelling full-scale point-neuron microcircuits (Scientific Reports, (2022), 12, 1, (13864), 10.1038/s41598-022-18024-y)
Daniela Gandolfi, Jonathan Mapelli, Sergio Solinas, Robin De Schepper, Alice Geminiani, Claudia Casellato, Egidio D’Angelo, Michele Migliore
Scientific Reports, 2022
Deconstruction of Neurotrypsin Reveals a Multi-factorially Regulated Activity Affecting Myotube Formation and Neuronal Excitability
Anselmo Canciani, Cristina Capitanio, Serena Stanga, Silvia Faravelli, Luigi Scietti, Lisa Mapelli, Teresa Soda, Egidio D’Angelo, Pascal Kienlen-Campard, Federico Forneris
Molecular Neurobiology, 2022
MRI data quality assessment for the RIN - Neuroimaging Network using the ACR phantoms
Fulvia Palesi, Anna Nigri, Ruben Gianeri, Domenico Aquino, Alberto Redolfi, Laura Biagi, Irene Carne, Silvia De Francesco, Stefania Ferraro, Paola Martucci, Jean Paul Medina, Antonio Napolitano, Alice Pirastru, Francesca Baglio, Fabrizio Tagliavini, Maria Grazia Bruzzone, Michela Tosetti, Claudia A.M. Gandini Wheeler-Kingshott
Physica Medica, 2022
Multi-centre and multi-vendor reproducibility of a standardized protocol for quantitative susceptibility Mapping of the human brain at 3T
Marta Lancione, Paolo Bosco, Mauro Costagli, Anna Nigri, Domenico Aquino, Irene Carne, Stefania Ferraro, Giovanni Giulietti, Antonio Napolitano, Fulvia Palesi, Luigi Pavone, Alice Pirastru, Giovanni Savini, Fabrizio Tagliavini, Maria Grazia Bruzzone, Claudia A.M. Gandini Wheeler-Kingshott, Michela Tosetti, Laura Biagi
Physica Medica, 2022
Computational models of neurotransmission at cerebellar synapses unveil the impact on network computation
Stefano Masoli, Martina Francesca Rizza, Marialuisa Tognolina, Francesca Prestori, Egidio D’Angelo
Frontiers in Computational Neuroscience, 2022
The quest for multiscale brain modeling
Egidio D’Angelo, Viktor Jirsa
Trends in Neurosciences, 2022
Bayesian Integration in a Spiking Neural System for Sensorimotor Control
Massimo Grillo, Alice Geminiani, Cristiano Alessandro, Egidio D'Angelo, Alessandra Pedrocchi, Claudia Casellato
Neural Computation, 2022
Subject-specific features of excitation/inhibition profiles in neurodegenerative diseases
Anita Monteverdi, Fulvia Palesi, Alfredo Costa, Paolo Vitali, Anna Pichiecchio, Matteo Cotta Ramusino, Sara Bernini, Viktor Jirsa, Claudia A. M. Gandini Wheeler-Kingshott, Egidio D’Angelo
Frontiers in Aging Neuroscience, 2022
Cerebellum Involvement in Dystonia During Associative Motor Learning: Insights From a Data-Driven Spiking Network Model
Alice Geminiani, Aurimas Mockevičius, Egidio D’Angelo, Claudia Casellato
Frontiers in Systems Neuroscience, 2022
Brain-Inspired Spiking Neural Network Controller for a Neurorobotic Whisker System
Alberto Antonietti, Alice Geminiani, Edoardo Negri, Egidio D'Angelo, Claudia Casellato, Alessandra Pedrocchi
Frontiers in Neurorobotics, 2022
Emergence of associative learning in a neuromorphic inference network
Daniela Gandolfi, Francesco M Puglisi, Giulia M Boiani, Giuseppe Pagnoni, Karl J Friston, Egidio D’Angelo, Jonathan Mapelli
Journal of Neural Engineering, 2022
Quantitative MRI Harmonization to Maximize Clinical Impact: The RIN–Neuroimaging Network
Anna Nigri, Stefania Ferraro, Claudia A. M. Gandini Wheeler-Kingshott, Michela Tosetti, Alberto Redolfi, Gianluigi Forloni, Egidio D'Angelo, Domenico Aquino, Laura Biagi, Paolo Bosco, Irene Carne, Silvia De Francesco, Greta Demichelis, Ruben Gianeri, Maria Marcella Lagana, Edoardo Micotti, Antonio Napolitano, Fulvia Palesi, Alice Pirastru, Giovanni Savini, Elisa Alberici, Carmelo Amato, Filippo Arrigoni, Francesca Baglio, Marco Bozzali, Antonella Castellano, Carlo Cavaliere, Valeria Elisa Contarino, Giulio Ferrazzi, Simona Gaudino, Silvia Marino, Vittorio Manzo, Luigi Pavone, Letterio S. Politi, Luca Roccatagliata, Elisa Rognone, Andrea Rossi, Caterina Tonon, Raffaele Lodi, Fabrizio Tagliavini, Maria Grazia Bruzzone, and
Frontiers in Neurology, 2022
The Cerebellar Involvement in Autism Spectrum Disorders: From the Social Brain to Mouse Models
Lisa Mapelli, Teresa Soda, Egidio D’Angelo, Francesca Prestori
International Journal of Molecular Sciences, 2022
Discovering Microcircuit Secrets With Multi-Spot Imaging and Electrophysiological Recordings: The Example of Cerebellar Network Dynamics
Marialuisa Tognolina, Anita Monteverdi, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2022
Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition
Giuseppe Gagliano, Anita Monteverdi, Stefano Casali, Umberto Laforenza, Claudia A. M. Gandini Wheeler-Kingshott, Egidio D’Angelo, Lisa Mapelli
Cells, 2022
Cerebellum involvement in dystonia: insights from a spiking neural network model during associative learning
Alice Geminiani, Aurimas Mockevicius, Egidio D'Angelo, Claudia Casellato
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBS, 2022
Modeling Early Phases of COVID-19 Pandemic in Northern Italy and Its Implication for Outbreak Diffusion
Daniela Gandolfi, Giuseppe Pagnoni, Tommaso Filippini, Alessia Goffi, Marco Vinceti, Egidio D'Angelo, Jonathan Mapelli
Frontiers in Public Health, 2021
Stellate cell computational modeling predicts signal filtering in the molecular layer circuit of cerebellum
Martina Francesca Rizza, Francesca Locatelli, Stefano Masoli, Diana Sánchez-Ponce, Alberto Muñoz, Francesca Prestori, Egidio D’Angelo
Scientific Reports, 2021
The effects of the general anesthetic sevoflurane on neurotransmission: an experimental and computational study
Jonathan Mapelli, Daniela Gandolfi, Enrico Giuliani, Stefano Casali, Luigi Congi, Alberto Barbieri, Egidio D’Angelo, Albertino Bigiani
Scientific Reports, 2021
Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?
Kurt G. Schilling, François Rheault, Laurent Petit, Colin B. Hansen, Vishwesh Nath, Fang-Cheng Yeh, Gabriel Girard, Muhamed Barakovic, Jonathan Rafael-Patino, Thomas Yu, Elda Fischi-Gomez, Marco Pizzolato, Mario Ocampo-Pineda, Simona Schiavi, Erick J. Canales-Rodríguez, Alessandro Daducci, Cristina Granziera, Giorgio Innocenti, Jean-Philippe Thiran, Laura Mancini, Stephen Wastling, Sirio Cocozza, Maria Petracca, Giuseppe Pontillo, Matteo Mancini, Sjoerd B. Vos, Vejay N. Vakharia, John S. Duncan, Helena Melero, Lidia Manzanedo, Emilio Sanz-Morales, Ángel Peña-Melián, Fernando Calamante, Arnaud Attyé, Ryan P. Cabeen, Laura Korobova, Arthur W. Toga, Anupa Ambili Vijayakumari, Drew Parker, Ragini Verma, Ahmed Radwan, Stefan Sunaert, Louise Emsell, Alberto De Luca, Alexander Leemans, Claude J. Bajada, Hamied Haroon, Hojjatollah Azadbakht, Maxime Chamberland, Sila Genc, Chantal M.W. Tax, Ping-Hong Yeh, Rujirutana Srikanchana, Colin D. Mcknight, Joseph Yuan-Mou Yang, Jian Chen, Claire E. Kelly, Chun-Hung Yeh, Jerome Cochereau, Jerome J. Maller, Thomas Welton, Fabien Almairac, Kiran K Seunarine, Chris A. Clark, Fan Zhang, Nikos Makris, Alexandra Golby, Yogesh Rathi, Lauren J. O'Donnell, Yihao Xia, Dogu Baran Aydogan, Yonggang Shi, Francisco Guerreiro Fernandes, Mathijs Raemaekers, Shaun Warrington, Stijn Michielse, Alonso Ramírez-Manzanares, Luis Concha, Ramón Aranda, Mariano Rivera Meraz, Garikoitz Lerma-Usabiaga, Lucas Roitman, Lucius S. Fekonja, Navona Calarco, Michael Joseph, Hajer Nakua, Aristotle N. Voineskos, Philippe Karan, Gabrielle Grenier, Jon Haitz Legarreta, Nagesh Adluru, Veena A. Nair, Vivek Prabhakaran, Andrew L. Alexander, Koji Kamagata, Yuya Saito, Wataru Uchida, Christina Andica, Masahiro Abe, Roza G. Bayrak, Claudia A.M. Gandini Wheeler-Kingshott, Egidio D'Angelo, Fulvia Palesi, Giovanni Savini, Nicolò Rolandi, Pamela Guevara, Josselin Houenou, Narciso López-López, Jean-François Mangin, Cyril Poupon, Claudio Román, Andrea Vázquez, Chiara Maffei, Mavilde Arantes, José Paulo Andrade, Susana Maria Silva, Vince D. Calhoun, Eduardo Caverzasi, Simone Sacco, Michael Lauricella, Franco Pestilli, Daniel Bullock, Yang Zhan, Edith Brignoni-Perez, Catherine Lebel, Jess E Reynolds, Igor Nestrasil, René Labounek, Christophe Lenglet, Amy Paulson, Stefania Aulicka, Sarah R. Heilbronner, Katja Heuer, Bramsh Qamar Chandio, Javier Guaje, Wei Tang, Eleftherios Garyfallidis, Rajikha Raja, Adam W. Anderson, Bennett A. Landman, Maxime Descoteaux
Neuroimage, 2021
Motor and higher-order functions topography of the human dentate nuclei identified with tractography and clustering methods
Fulvia Palesi, Matteo Ferrante, Marta Gaviraghi, Anastasia Misiti, Giovanni Savini, Alessandro Lascialfari, Egidio D'Angelo, Claudia A. M. Gandini Wheeler‐Kingshott
Human Brain Mapping, 2021
Towards a Bio-Inspired Real-Time Neuromorphic Cerebellum
Petruţ A. Bogdan, Beatrice Marcinnò, Claudia Casellato, Stefano Casali, Andrew G.D. Rowley, Michael Hopkins, Francesco Leporati, Egidio D'Angelo, Oliver Rhodes
Frontiers in Cellular Neuroscience, 2021
Production and diffusion model of nitric oxide for bioinspired spiking neural networks
Alessandra Trapani, Alberto Antonietti, Giovanni Naldi, Egidio D'Angelo, Alessandra Pedrocchi
International IEEE EMBS Conference on Neural Engineering Ner, 2021
Implementation of the nucleocortical pathways inside a spiking neural network model of cerebellar nuclei
Massimo Grillo, Alice Geminiani, Alberto Antonietti, Egidio D'Angelo, Alessandra Pedrocchi
International IEEE EMBS Conference on Neural Engineering Ner, 2021
Blood Oxygenation Level-Dependent Response to Multiple Grip Forces in Multiple Sclerosis: Going Beyond the Main Effect of Movement in Brodmann Area 4a and 4p
Adnan A. S. Alahmadi, Matteo Pardini, Rebecca S. Samson, Egidio D’Angelo, Karl J. Friston, Ahmed T. Toosy, Claudia A. M. Gandini Wheeler-Kingshott
Frontiers in Cellular Neuroscience, 2021
Calcium channel-dependent induction of long-term synaptic plasticity at excitatory golgi cell synapses of cerebellum
F. Locatelli, T. Soda, I. Montagna, S. Tritto, L. Botta, F. Prestori, E. D'Angelo
Journal of Neuroscience, 2021
Real-Time Simulation of a Cerebellar Scaffold Model on Graphics Processing Units
Rin Kuriyama, Claudia Casellato, Egidio D'Angelo, Tadashi Yamazaki
Frontiers in Cellular Neuroscience, 2021
Granular layEr Simulator: Design and Multi-GPU Simulation of the Cerebellar Granular Layer
Giordana Florimbi, Emanuele Torti, Stefano Masoli, Egidio D'Angelo, Francesco Leporati
Frontiers in Computational Neuroscience, 2021
Cerebellar Granule Cell
Egidio D’Angelo
Handbook of the Cerebellum and Cerebellar Disorders Second Edition Volume 3, 2021
Computational Modelling of Cerebellar Magnetic Stimulation: The Effect of Washout
Alberto Antonietti, Claudia Casellato, Egidio D’Angelo, Alessandra Pedrocchi
Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2021
Automatic Segmentation of Dentate Nuclei for Microstructure Assessment: Example of Application to Temporal Lobe Epilepsy Patients
Marta Gaviraghi, Giovanni Savini, Gloria Castellazzi, Fulvia Palesi, Nicolò Rolandi, et al.
Mathematics and Visualization, 2021
Cerebellar Golgi cell models predict dendritic processing and mechanisms of synaptic plasticity
Stefano Masoli, Alessandra Ottaviani, Stefano Casali, Egidio D’Angelo
Plos Computational Biology, 2020
Parameter tuning differentiates granule cell subtypes enriching transmission properties at the cerebellum input stage
Stefano Masoli, Marialuisa Tognolina, Umberto Laforenza, Francesco Moccia, Egidio D’Angelo
Communications Biology, 2020
Cellular-resolution mapping uncovers spatial adaptive filtering at the rat cerebellum input stage
Stefano Casali, Marialuisa Tognolina, Daniela Gandolfi, Jonathan Mapelli, Egidio D’Angelo
Communications Biology, 2020
Frontal and Cerebellar Atrophy Supports FTSD-ALS Clinical Continuum
Beatrice Pizzarotti, Fulvia Palesi, Paolo Vitali, Gloria Castellazzi, Nicoletta Anzalone, Elena Alvisi, Daniele Martinelli, Sara Bernini, Matteo Cotta Ramusino, Mauro Ceroni, Giuseppe Micieli, Elena Sinforiani, Egidio D’Angelo, Alfredo Costa, Claudia A. M. Gandini Wheeler-Kingshott
Frontiers in Aging Neuroscience, 2020
Medical Informatics Platform (MIP): A Pilot Study Across Clinical Italian Cohorts
Alberto Redolfi, Silvia De Francesco, Fulvia Palesi, Samantha Galluzzi, Cristina Muscio, Gloria Castellazzi, Pietro Tiraboschi, Giovanni Savini, Anna Nigri, Gabriella Bottini, Maria Grazia Bruzzone, Matteo Cotta Ramusino, Stefania Ferraro, Claudia A. M. Gandini Wheeler-Kingshott, Fabrizio Tagliavini, Giovanni B. Frisoni, Philippe Ryvlin, Jean-François Demonet, Ferath Kherif, Stefano F. Cappa, Egidio D'Angelo
Frontiers in Neurology, 2020
The Importance of Cerebellar Connectivity on Simulated Brain Dynamics
Fulvia Palesi, Roberta Maria Lorenzi, Claudia Casellato, Petra Ritter, Viktor Jirsa, Claudia A.M. Gandini Wheeler-Kingshott, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2020
A Machine Learning Approach for the Differential Diagnosis of Alzheimer and Vascular Dementia Fed by MRI Selected Features
Gloria Castellazzi, Maria Giovanna Cuzzoni, Matteo Cotta Ramusino, Daniele Martinelli, Federica Denaro, Antonio Ricciardi, Paolo Vitali, Nicoletta Anzalone, Sara Bernini, Fulvia Palesi, Elena Sinforiani, Alfredo Costa, Giuseppe Micieli, Egidio D'Angelo, Giovanni Magenes, Claudia A. M. Gandini Wheeler-Kingshott
Frontiers in Neuroinformatics, 2020
The optogenetic revolution in cerebellar investigations
Francesca Prestori, Ileana Montagna, Egidio D’Angelo, Lisa Mapelli
International Journal of Molecular Sciences, 2020
Deletion of calcineurin from GFAP-expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na+/K+ ATPase
Laura Tapella, Teresa Soda, Lisa Mapelli, Valeria Bortolotto, Heather Bondi, Federico A. Ruffinatti, Giulia Dematteis, Alessio Stevano, Marianna Dionisi, Simone Ummarino, Annalisa Di Ruscio, Carla Distasi, Mariagrazia Grilli, Armando A. Genazzani, Egidio D'Angelo, Francesco Moccia, Dmitry Lim
GLIA, 2020
Unsuspected Involvement of Spinal Cord in Alzheimer Disease
Roberta Maria Lorenzi, Fulvia Palesi, Gloria Castellazzi, Paolo Vitali, Nicoletta Anzalone, Sara Bernini, Matteo Cotta Ramusino, Elena Sinforiani, Giuseppe Micieli, Alfredo Costa, Egidio D’Angelo, Claudia A. M. Gandini Wheeler-Kingshott
Frontiers in Cellular Neuroscience, 2020
Disrupted calcium signaling in animal models of human spinocerebellar ataxia (SCA)
Francesca Prestori, Francesco Moccia, Egidio D’Angelo
International Journal of Molecular Sciences, 2020
Erratum: Control of a humanoid NAO robot by an adaptive bioinspired cerebellar module in 3D motion tasks (Computational Intelligence and Neuroscience (2019) 2019 (4862157) DOI: 10.1155/2019/4862157)
Alberto Antonietti, Dario Martina, Claudia Casellato, Egidio D’Angelo, Alessandra Pedrocchi
Computational Intelligence and Neuroscience, 2020
Diverse Neuron Properties and Complex Network Dynamics in the Cerebellar Cortical Inhibitory Circuit
Francesca Prestori, Lisa Mapelli, Egidio D’Angelo
Frontiers in Molecular Neuroscience, 2019
Response Dynamics in an Olivocerebellar Spiking Neural Network With Non-linear Neuron Properties
Alice Geminiani, Alessandra Pedrocchi, Egidio D’Angelo, Claudia Casellato
Frontiers in Computational Neuroscience, 2019
Erratum: Hyperexcitability and hyperplasticity disrupt cerebellar signal transfer in the ib2 ko mouse model of autism (Journal of Neuroscience (2019) (2383-2397) DOI: 10.1523/JNEUROSCI.1985-18.2019)
Christian Keitel, Anne Keitel, Christopher Benwell, Christoph Daube, Gregor Thut, et al.
Journal of Neuroscience, 2019
Corrigendum: Long-lasting response changes in deep cerebellar nuclei in vivo correlate with low-frequency oscillations (Frontiers in Cellular Neuroscience, (2019), 13, 10.3389/fncel.2019.00084)
Letizia Moscato, Ileana Montagna, Licia De Propris, Simona Tritto, Lisa Mapelli, Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2019
Corrigendum: Complex electroresponsive dynamics in olivocerebellar neurons represented with extended-generalized leaky integrate and fire models (Front. Comput. Neurosci., (2019), 13, 10.3389/fncom.2019.00035)
Alice Geminiani, Claudia Casellato, Egidio D'Angelo, Alessandra Pedrocchi
Frontiers in Computational Neuroscience, 2019
Corrigendum: Reconstruction and simulation of a scaffold model of the cerebellar network (Front. Neuroinform., (2019), 13, 10.3389/fninf.2019.00037)
Stefano Casali, Elisa Marenzi, Chaitanya Medini, Claudia Casellato, Egidio D'Angelo
Frontiers in Neuroinformatics, 2019
Corrigendum: Complex dynamics in simplified neuronal models: Reproducing golgi cell electroresponsiveness (Front. Neuroinform., (2018), 12, 10.3389/fninf.2018.00088)
Alice Geminiani, Claudia Casellato, Francesca Locatelli, Francesca Prestori, Alessandra Pedrocchi, Egidio D'Angelo
Frontiers in Neuroinformatics, 2019
Implementation of an Advanced Frequency-Based Hebbian Spike Timing Dependent Plasticity
Alberto Antonietti, Vasco Orza, Claudia Casellato, Egidio D'Angelo, Alessandra Pedrocchi
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBS, 2019
The Human Brain Project—Synergy between neuroscience, computing, informatics, and brain-inspired technologies
Katrin Amunts, Alois C. Knoll, Thomas Lippert, Cyriel M. A. Pennartz, Philippe Ryvlin, Alain Destexhe, Viktor K. Jirsa, Egidio D’Angelo, Jan G. Bjaalie
Plos Biology, 2019
Complex electroresponsive dynamics in olivocerebellar neurons represented with extended-generalized leaky integrate and fire models
Alice Geminiani, Claudia Casellato, Egidio D’Angelo, Alessandra Pedrocchi
Frontiers in Computational Neuroscience, 2019
Reconstruction and simulation of a scaffold model of the cerebellar network
Stefano Casali, Elisa Marenzi, Chaitanya Medini, Claudia Casellato, Egidio D'Angelo
Frontiers in Neuroinformatics, 2019
Consensus paper: Decoding the Contributions of the Cerebellum as a Time Machine. From Neurons to Clinical Applications
Martin Bareš, Richard Apps, Laura Avanzino, Assaf Breska, Egidio D’Angelo, Pavel Filip, Marcus Gerwig, Richard B. Ivry, Charlotte L. Lawrenson, Elan D. Louis, Nicholas A. Lusk, Mario Manto, Warren H. Meck, Hiroshi Mitoma, Elijah A. Petter
Cerebellum, 2019
Exploiting multi-core and many-core architectures for efficient simulation of biologically realistic models of Golgi cells
Giordana Florimbi, Emanuele Torti, Stefano Masoli, Egidio D’Angelo, Giovanni Danese, Francesco Leporati
Journal of Parallel and Distributed Computing, 2019
Glutamate triggers intracellular Ca 2+ oscillations and nitric oxide release by inducing NAADP- and InsP 3 -dependent Ca 2+ release in mouse brain endothelial cells
Estella Zuccolo, Dlzar A. Kheder, Dmitry Lim, Angelica Perna, Francesca Di Nezza, Laura Botta, Giorgia Scarpellino, Sharon Negri, Simona Martinotti, Teresa Soda, Greta Forcaia, Laura Riboni, Elia Ranzato, Giulio Sancini, Luigi Ambrosone, Egidio D’Angelo, Germano Guerra, Francesco Moccia
Journal of Cellular Physiology, 2019
Hyperexcitability and hyperplasticity disrupt cerebellar signal transfer in the IB2 KO mouse model of autism
Teresa Soda, Lisa Mapelli, Francesca Locatelli, Laura Botta, Mitchell Goldfarb, Francesca Prestori, Egidio D'Angelo
Journal of Neuroscience, 2019
GPU Parallelization of Realistic Purkinje Cells with Complex Morphology
Emanuele Torti, Stefano Masoli, Giordana Florimbi, Egidio D'Angelo, Marta Ticli, Francesco Leporati
Proceedings 27th Euromicro International Conference on Parallel Distributed and Network Based Processing Pdp 2019, 2019
I see your effort: Force-Related BOLD effects in an extended action execution-observation network involving the cerebellum
Letizia Casiraghi, Adnan A S Alahmadi, Anita Monteverdi, Fulvia Palesi, Gloria Castellazzi, Giovanni Savini, Karl Friston, Claudia A M Gandini Wheeler-Kingshott, Egidio D’Angelo
Cerebral Cortex, 2019
Long-lasting response changes in deep cerebellar nuclei In vivo correlate with low-frequency oscillations
Letizia Moscato, Ileana Montagna, Licia De Propris, Simona Tritto, Lisa Mapelli, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2019
Default mode network structural integrity and cerebellar connectivity predict information processing speed deficit in multiple sclerosis
Giovanni Savini, Matteo Pardini, Gloria Castellazzi, Alessandro Lascialfari, Declan Chard, Egidio D’Angelo, Claudia A. M. Gandini Wheeler-Kingshott
Frontiers in Cellular Neuroscience, 2019
The cerebellum gets social
Egidio D'Angelo
Science, 2019
A flashback at the first 40 years of the Mondino IRCCS: 1973-2013
Confinia Cephalalgica, 2019
Control of a humanoid NAO robot by an adaptive bioinspired cerebellar module in 3D Motion tasks
Alberto Antonietti, Dario Martina, Claudia Casellato, Egidio D’Angelo, Alessandra Pedrocchi
Computational Intelligence and Neuroscience, 2019
Complex dynamics in simplified neuronal models: Reproducing golgi cell electroresponsiveness
Alice Geminiani, Claudia Casellato, Francesca Locatelli, Francesca Prestori, Alessandra Pedrocchi, Egidio D'Angelo
Frontiers in Neuroinformatics, 2018
TMS over the Cerebellum Interferes with Short-term Memory of Visual Sequences
C. Ferrari, Z. Cattaneo, V. Oldrati, L. Casiraghi, F. Castelli, E. D’Angelo, T. Vecchi
Scientific Reports, 2018
Potentiation of cerebellar purkinje cells facilitates whisker reflex adaptation through increased simple spike activity
Vincenzo Romano, Licia De Propris, Laurens WJ Bosman, Pascal Warnaar, Michiel M ten Brinke, Sander Lindeman, Chiheng Ju, Arthiha Velauthapillai, Jochen K Spanke, Emily Middendorp Guerra, Tycho M Hoogland, Mario Negrello, Egidio D'Angelo, Chris I De Zeeuw
Elife, 2018
Challenges and perspectives of quantitative functional sodium imaging (fNaI)
Claudia A. M. Gandini Wheeler-Kingshott, Frank Riemer, Fulvia Palesi, Antonio Ricciardi, Gloria Castellazzi, Xavier Golay, Ferran Prados, Bhavana Solanky, Egidio U. D’Angelo
Frontiers in Neuroscience, 2018
Dynamic Redistribution of Plasticity in a Cerebellar Spiking Neural Network Reproducing an Associative Learning Task Perturbed by TMS
Alberto Antonietti, Jessica Monaco, Egidio D'Angelo, Alessandra Pedrocchi, Claudia Casellato
International Journal of Neural Systems, 2018
Prominent changes in cerebro-cerebellar functional connectivity during continuous cognitive processing
Gloria Castellazzi, Stefania D. Bruno, Ahmed T. Toosy, Letizia Casiraghi, Fulvia Palesi, Giovanni Savini, Egidio D’Angelo, Claudia Angela Michela Gandini Wheeler-Kingshott
Frontiers in Cellular Neuroscience, 2018
Functional connectivity alterations reveal complex mechanisms based on clinical and radiological status in mild relapsing remitting multiple sclerosis
Gloria Castellazzi, Laetitia Debernard, Tracy R. Melzer, John C. Dalrymple-Alford, Egidio D'Angelo, David H. Miller, Claudia A. M. Gandini Wheeler-Kingshott, Deborah F. Mason
Frontiers in Neurology, 2018
Cerebellar learning properties are modulated by the CRF receptor
Gili Ezra-Nevo, Francesca Prestori, Francesca Locatelli, Teresa Soda, Michiel M. ten Brinke, Mareen Engel, Henk-Jan Boele, Laura Botta, Dena Leshkowitz, Assaf Ramot, Michael Tsoory, Inbal E. Biton, Jan Deussing, Egidio D'Angelo, Chris I. De Zeeuw, Alon Chen
Journal of Neuroscience, 2018
A Multiple-Plasticity Spiking Neural Network Embedded in a Closed-Loop Control System to Model Cerebellar Pathologies
Alice Geminiani, Claudia Casellato, Alberto Antonietti, Egidio D’Angelo, Alessandra Pedrocchi
International Journal of Neural Systems, 2018
The role of the cerebellum in multiple sclerosis—150 years after Charcot
Katrin Parmar, Christine Stadelmann, Maria A. Rocca, Dawn Langdon, Egidio D'Angelo, Marcus D’Souza, Jessica Burggraaff, Christiane Wegner, Jaume Sastre-Garriga, Alonso Barrantes-Freer, Jonas Dorn, Bernard M.J. Uitdehaag, Xavier Montalban, Jens Wuerfel, Christian Enzinger, Alex Rovira, Mar Tintore, Massimo Filippi, Ludwig Kappos, Till Sprenger
Neuroscience and Biobehavioral Reviews, 2018
Specific patterns of white matter alterations help distinguishing Alzheimer's and vascular dementia
Fulvia Palesi, Andrea De Rinaldis, Paolo Vitali, Gloria Castellazzi, Letizia Casiraghi, Giancarlo Germani, Sara Bernini, Nicoletta Anzalone, Matteo Cotta Ramusino, Federica M. Denaro, Elena Sinforiani, Alfredo Costa, Giovanni Magenes, Egidio D'Angelo, Claudia A. M. Gandini Wheeler-Kingshott, Giuseppe Micieli
Frontiers in Neuroscience, 2018
Understanding Cerebellum Granular Layer Network Computations through Mathematical Reconstructions of Evoked Local Field Potentials
Harilal Parasuram, Bipin Nair, Giovanni Naldi, Egidio D’Angelo, Shyam Diwakar
Annals of Neurosciences, 2018
Correspondence
Syed Ather Hussain, Vinod C. Nayak, Ritesh G. Menezes
Nature, 2018
Physiology of the cerebellum
Egidio D’Angelo
Handbook of Clinical Neurology, 2018
Cerebellar theta-burst stimulation impairs memory consolidation in eyeblink classical conditioning
Jessica Monaco, Lorenzo Rocchi, Francesca Ginatempo, Egidio D'Angelo, John C. Rothwell
Neural Plasticity, 2018
Contralateral cortico-ponto-cerebellar pathways reconstruction in humans in vivo: Implications for reciprocal cerebro-cerebellar structural connectivity in motor and non-motor areas
Fulvia Palesi, Andrea De Rinaldis, Gloria Castellazzi, Fernando Calamante, Nils Muhlert, Declan Chard, J. Donald Tournier, Giovanni Magenes, Egidio D’Angelo, Claudia A. M. Gandini Wheeler-Kingshott
Scientific Reports, 2017
Model-driven analysis of eyeblink classical conditioning reveals the underlying structure of cerebellar plasticity and neuronal activity
Alberto Antonietti, Claudia Casellato, Egidio D'Angelo, Alessandra Pedrocchi
IEEE Transactions on Neural Networks and Learning Systems, 2017
Synaptic activation of a detailed Purkinje cell model predicts voltage-dependent control of burst-pause responses in active dendrites
Stefano Masoli, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2017
Acetylcholine induces intracellular Ca2+ oscillations and nitric oxide release in mouse brain endothelial cells
Estella Zuccolo, Dmitry Lim, Dlzar Ali Kheder, Angelica Perna, Paolo Catarsi, Laura Botta, Vittorio Rosti, Laura Riboni, Giulio Sancini, Franco Tanzi, Egidio D’Angelo, Germano Guerra, Francesco Moccia
Cell Calcium, 2017
Spiking cerebellar model with damaged cortical Neural population reproduces human ataxic behaviors in perturbed upper limb reaching
Alice Geminiani, Alessandra Pedrocchi, Egidio D'Angelo, Claudia Casellato
International IEEE EMBS Conference on Neural Engineering Ner, 2017
After Effects of Cerebellar Continuous Theta Burst Stimulation on Reflexive Saccades and Smooth Pursuit in Humans
Silvia Colnaghi, P. Colagiorgio, S. Ramat, E. D’Angelo, G. Koch, M. Versino
Cerebellum, 2017
Modelling the brain: Elementary components to explain ensemble functions
Egidio D’Angelo, Claudia A. M. Gandini Wheeler‐Kingshott
Rivista Del Nuovo Cimento, 2017
A role for NMDAR-dependent cerebellar plasticity in adaptive control of saccades in humans
S. Colnaghi, P. Colagiorgio, M. Versino, G. Koch, E. D'Angelo, S. Ramat
Brain Stimulation, 2017
Activation of the CREB/c-Fos pathway during long-term synaptic plasticity in the cerebellum granular layer
Daniela Gandolfi, Silvia Cerri, Jonathan Mapelli, Mariarosa Polimeni, Simona Tritto, Marie-Therese Fuzzati-Armentero, Albertino Bigiani, Fabio Blandini, Lisa Mapelli, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2017
Cerebellar lobules and dentate nuclei mirror cortical force-related-BOLD responses: Beyond all (linear) expectations
Adnan A.S Alahmadi, Matteo Pardini, Rebecca S. Samson, Karl J. Friston, Ahmed T. Toosy, Egidio D'Angelo, Claudia A.M. Gandini Wheeler‐Kingshott
Human Brain Mapping, 2017
Hebbian spike-timing dependent plasticity at the cerebellar input stage
Martina Sgritta, Francesca Locatelli, Teresa Soda, Francesca Prestori, Egidio Ugo D'Angelo
Journal of Neuroscience, 2017
Single neuron optimization as a basis for accurate biophysical modeling: The case of cerebellar granule cells
Stefano Masoli, Martina F. Rizza, Martina Sgritta, Werner Van Geit, Felix Schürmann, Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2017
Granular layer neurons control cerebellar neurovascular coupling through an NMDA receptor/NO-dependent system
Lisa Mapelli, Giuseppe Gagliano, Teresa Soda, Umberto Laforenza, Francesco Moccia, Egidio U. D'Angelo
Journal of Neuroscience, 2017
Challenging Marr’s theory of the cerebellum
Egidio D’Angelo
Computational Theories and their Implementation in the Brain the Legacy of David Marr, 2017
The past and future of functional neurology
Egidio D�Angelo
Functional Neurology, 2017
Repetitive TMS on left cerebellum affects impulsivity in borderline personality disorder: A pilot study
Giulia Zelda De Vidovich, Riccardo Muffatti, Jessica Monaco, Nicoletta Caramia, Davide Broglia, Edgardo Caverzasi, Francesco Barale, Egidio D’Angelo
Frontiers in Human Neuroscience, 2016
Biotic/abiotic stress-driven Alzheimer’s disease
Chang-Qing Li, Qing Zheng, Qi Wang, Qing-Ping Zeng
Frontiers in Cellular Neuroscience, 2016
The Human Brain Project: Parallel technologies for biologically accurate simulation of Granule cells
Giordana Florimbi, Emanuele Torti, Stefano Masoli, Egidio D'Angelo, Giovanni Danese, Francesco Leporati
Microprocessors and Microsystems, 2016
Reconstructing contralateral fiber tracts: Methodological aspects of cerebello-thalamo-cortical pathway reconstruction
Fulvia Plaesi
Functional Neurology, 2016
FHF-independent conduction of action potentials along the leak-resistant cerebellar granule cell axon
Katarzyna Dover, Christopher Marra, Sergio Solinas, Marko Popovic, Sathyaa Subramaniyam, Dejan Zecevic, Egidio D’Angelo, Mitchell Goldfarb
Nature Communications, 2016
Exploring patterns of Alteration in Alzheimer's disease brain networks: A combined structural and functional connectomics analysis
Fulvia Palesi, Gloria Castellazzi, Letizia Casiraghi, Elena Sinforiani, Paolo Vitali, Claudia A. M. Gandini Wheeler-Kingshott, Egidio D'Angelo
Frontiers in Neuroscience, 2016
Oscillation-Driven Spike-Timing Dependent Plasticity Allows Multiple Overlapping Pattern Recognition in Inhibitory Interneuron Networks
Jesús A. Garrido, Niceto R. Luque, Silvia Tolu, Egidio D’Angelo
International Journal of Neural Systems, 2016
Modeling the cerebellar microcircuit: New strategies for a long-standing issue
Egidio D’Angelo, Alberto Antonietti, Stefano Casali, Claudia Casellato, Jesus A. Garrido, Niceto Rafael Luque, Lisa Mapelli, Stefano Masoli, Alessandra Pedrocchi, Francesca Prestori, Martina Francesca Rizza, Eduardo Ros
Frontiers in Cellular Neuroscience, 2016
Computational modeling of single neuron extracellular electric potentials and network local field potentials using LFPsim
Harilal Parasuram, Bipin Nair, Egidio D'Angelo, Michael Hines, Giovanni Naldi, Shyam Diwakar
Frontiers in Computational Neuroscience, 2016
Complex motor task associated with non-linear BOLD responses in cerebro-cortical areas and cerebellum
Adnan A. S. Alahmadi, Rebecca S. Samson, David Gasston, Matteo Pardini, Karl J. Friston, Egidio D’Angelo, Ahmed T. Toosy, Claudia A. M. Wheeler-Kingshott
Brain Structure and Function, 2016
Distributed Circuit Plasticity: New Clues for the Cerebellar Mechanisms of Learning
Egidio D’Angelo, Lisa Mapelli, Claudia Casellato, Jesus A. Garrido, Niceto Luque, Jessica Monaco, Francesca Prestori, Alessandra Pedrocchi, Eduardo Ros
Cerebellum, 2016
Distributed cerebellar motor learning: A spike-timing-dependent plasticity model
Niceto R. Luque, Jesús A. Garrido, Francisco Naveros, Richard R. Carrillo, Egidio D'Angelo, Eduardo Ros
Frontiers in Computational Neuroscience, 2016
Tactile stimulation evokes long-lasting potentiation of purkinje cell discharge in vivo
K. B. Ramakrishnan, Kai Voges, Licia De Propris, Chris I. De Zeeuw, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2016
Editorial: The olivo-cerebellar system
Egidio D'Angelo, Elisa Galliano, Chris I. De Zeeuw
Frontiers in Neural Circuits, 2016
Distributed plasticity in the cerebellar circuit
Egidio D’Angelo
Essentials of Cerebellum and Cerebellar Disorders A Primer for Graduate Students, 2016
Granule cells and parallel fibers
Egidio D’Angelo
Essentials of Cerebellum and Cerebellar Disorders A Primer for Graduate Students, 2016
Single-Neuron and Network Computation in Realistic Models of the Cerebellar Cortex
Egidio D’Angelo, Stefano Masoli, Martina Rizza, Stefano Casali
Neuronal Codes of the Cerebellum, 2016
A computational model of the cerebellum to simulate cortical degeneration during a pavlovian associative paradigm
Ifmbe Proceedings, 2016
A Computational Model of the Cerebellum to Simulate Cortical Degeneration During a Pavlovian Associative Paradigm
Alice Geminiani, Alberto Antonietti, Claudia Casellato, Egidio D’Angelo, Alessandra Pedrocchi
Ifmbe Proceedings, 2016
Spiking neural network with distributed plasticity reproduces cerebellar learning in eye blink conditioning paradigms
Alberto Antonietti, Claudia Casellato, Jesus A. Garrido, Niceto R. Luque, Francisco Naveros, Eduardo Ros, Egidio DAngelo, Alessandra Pedrocchi
IEEE Transactions on Biomedical Engineering, 2016
Differential involvement of cortical and cerebellar areas using dominant and nondominant hands: An FMRI study
Adnan A.S. Alahmadi, Matteo Pardini, Rebecca S. Samson, Egidio D'Angelo, Karl J. Friston, Ahmed T. Toosy, Claudia A.M. Gandini Wheeler‐Kingshott
Human Brain Mapping, 2015
Contralateral cerebello-thalamo-cortical pathways with prominent involvement of associative areas in humans in vivo
Fulvia Palesi, Jacques-Donald Tournier, Fernando Calamante, Nils Muhlert, Gloria Castellazzi, Declan Chard, Egidio D’Angelo, Claudia A. M. Wheeler-Kingshott
Brain Structure and Function, 2015
Healthy and pathological cerebellar Spiking Neural Networks in Vestibulo-Ocular Reflex
Alberto Antonietti, Claudia Casellato, Alice Geminiani, Egidio D'Angelo, Alessandra Pedrocchi
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBS, 2015
The human brain project: High performance computing for brain cells Hw/Sw simulation and understanding
Egidio D'Angelo, Giovanni Danese, Giordana Florimbi, Francesco Leporati, Alessandra Majani, Stefano Masoli, Sergio Solinas, Emanuele Torti
Proceedings 18th Euromicro Conference on Digital System Design Dsd 2015, 2015
The new challenge for Functional Neurology
Functional Neurology, 2015
Exploiting point source approximation on detailed neuronal models to reconstruct single neuron electric field and population LFP
Harilal Parasuram, Bipin Nair, Giovanni Naldi, Egidio D'Angelo, Shyam Diwakar
Proceedings of the International Joint Conference on Neural Networks, 2015
Reconstructing fMRI BOLD signals arising from cerebellar granule neurons - Comparing GLM and balloon models
Chaitanya Medini, Giovanni Naldi, Bipin Nair, Egidio D'Angelo, Shyam Diwakar
Proceedings of the International Joint Conference on Neural Networks, 2015
The Ettore Majorana international science center launches the first course of its Camillo Golgi international school of brain cells and circuits: Modeling the brain
E D'Angelo
Functional Neurology, 2015
Spiking cerebellar model with multiple plasticity sites reproduces eye blinking classical conditioning
Alberto Antonietti, Claudia Casellato, Jesus A. Garrido, Egidio D'Angelo, Alessandra Pedrocchi
International IEEE EMBS Conference on Neural Engineering Ner, 2015
Integrated plasticity at inhibitory and excitatory synapses in the cerebellar circuit
Lisa Mapelli, Martina Pagani, Jesus A. Garrido, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2015
STIM and Orai proteins in neuronal Ca2+ signaling and excitability
Francesco Moccia, Estella Zuccolo, Teresa Soda, Franco Tanzi, Germano Guerra, Lisa Mapelli, Francesco Lodola, Egidio D’Angelo
Frontiers in Cellular Neuroscience, 2015
The effect of desflurane on neuronal communication at a central synapse
Jonathan Mapelli, Daniela Gandolfi, Enrico Giuliani, Francesco P. Prencipe, Federica Pellati, Alberto Barbieri, Egidio D’Angelo, Albertino Bigiani
Plos One, 2015
Distributed cerebellar plasticity implements generalized multiple-scale memory components in real-robot sensorimotor tasks
Claudia Casellato, Alberto Antonietti, Jesus A. Garrido, Giancarlo Ferrigno, Egidio D'Angelo, Alessandra Pedrocchi
Frontiers in Computational Neuroscience, 2015
Action potential processing in a detailed Purkinje cell model reveals a critical role for axonal compartmentalization
Stefano Masoli, Sergio Solinas, Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2015
Long-term spatiotemporal reconfiguration of neuronal activity revealed by voltage-sensitive dye imaging in the cerebellar granular layer
Daniela Gandolfi, Jonathan Mapelli, Egidio D’Angelo
Neural Plasticity, 2015
High-throughput spatial light modulation two-photon microscopy for fast functional imaging
Paolo Pozzi, Daniela Gandolfi, Marialuisa Tognolina, Giuseppe Chirico, Jonathan Mapelli, Egidio D’Angelo
Neurophotonics, 2015
Adaptive robotic control driven by a versatile spiking cerebellar network
Claudia Casellato, Alberto Antonietti, Jesus A. Garrido, Richard R. Carrillo, Niceto R. Luque, Eduardo Ros, Alessandra Pedrocchi, Egidio D'Angelo
Plos One, 2014
Cerebellar theta burst stimulation dissociates memory components in eyeblink classical conditioning
J. Monaco, C. Casellato, G. Koch, E. D'Angelo
European Journal of Neuroscience, 2014
Model cerebellar granule cells can faithfully transmit modulated firing rate signals
Christian RÃ¶ssert, Sergio Solinas, Egidio D'Angelo, Paul Dean, John Porrill
Frontiers in Cellular Neuroscience, 2014
Computationally efficient bio-realistic reconstructions of cerebellar neuron spiking patterns
Chaitanya Medini, Asha Vijayan, Egidio D'Angelo, Bipin Nair, Shyam Diwakar
ACM International Conference Proceeding Series, 2014
Parallelization of a computational model of a biophysical neuronal circuitry of rat cerebellum
Afila Yoosef, Harilal Parasuram, Chaitanya Medini, Sergio Solinas, Egidio D'Angelo, Bipin Nair, Shyam Diwakar
ACM International Conference Proceeding Series, 2014
The urgent need for a systems biology approach to neurology
Functional Neurology, 2014
Phosphene induction by cerebellar transcranial magnetic stimulation
Chiara Renzi, Tomaso Vecchi, Egidio D’ Angelo, Juha Silvanto, Zaira Cattaneo
Clinical Neurophysiology, 2014
Distributed cerebellar plasticity implements multiple-scale memory components of vestibulo-ocular reflex in real-robots
Claudia Casellato, Alberto Antonietti, Jesus A. Garrido, Alessandra Pedrocchi, Egidio D'Angelo
Proceedings of the IEEE Ras and EMBS International Conference on Biomedical Robotics and Biomechatronics, 2014
Synapses as therapeutic targets for autism spectrum disorders: An international symposium held in pavia on July 4th, 2014
Paolo Curatolo, Yehezkel Ben-Ari, Yuri Bozzi, Maria Vincenza Catania, Egidio Dâ€™Angelo, Lisa Mapelli, Lindsay M. Oberman, Christian Rosenmund, Enrico Cherubini
Frontiers in Cellular Neuroscience, 2014
Cerebellar vermis plays a causal role in visual motion discrimination
Zaira Cattaneo, Chiara Renzi, Stefano Casali, Juha Silvanto, Tomaso Vecchi, Costanza Papagno, Egidio D'Angelo
Cortex, 2014
Regulation of output spike patterns by phasic inhibition in cerebellar granule cells
Thierry R. Nieus, Lisa Mapelli, Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2014
Computational modeling predicts the ionic mechanism of late-onset responses in unipolar brush cells
Sathyaa Subramaniyam, Sergio Solinas, Paola Perin, Francesca Locatelli, Sergio Masetto, Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2014
Fast convergence of learning requires plasticity between inferior olive and deep cerebellar nuclei in a manipulation task: A closed-loop robotic simulation
Niceto R. Luque, JesÃºs A. Garrido, Richard R. Carrillo, Egidio D'Angelo, Eduardo Ros
Frontiers in Computational Neuroscience, 2014
The spatiotemporal organization of cerebellar network activity resolved by two-photon imaging of multiple single neurons
Daniela Gandolfi, Paolo Pozzi, Marialuisa Tognolina, Giuseppe Chirico, Jonathan Mapelli, Egidio D'Angelo
Frontiers in Behavioral Neuroscience, 2014
Integration and regulation of glomerular inhibition in the cerebellar granular layer circuit
Lisa Mapelli, Sergio Solinas, Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2014
The Organization of Plasticity in the Cerebellar Cortex: From Synapses to Control
Egidio D'Angelo
Progress in Brain Research, 2014
Magnetic stimulation of the cerebellum. moving towards the clinic
Functional Neurology, 2014
A comprehensive assessment of resting state networks: Bidirectional modification of functional integrity in cerebro-cerebellar networks in dementia
Gloria Castellazzi, Fulvia Palesi, Stefano Casali, Paolo Vitali, Elena Sinforiani, Claudia A. M. Wheeler-Kingshott, Egidio D'Angelo
Frontiers in Neuroscience, 2014
Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons
A. Folci, L. Mapelli, J. Sassone, F. Prestori, E. D'Angelo, S. Bassani, M. Passafaro
Journal of Neuroscience, 2014
Brain-inspired sensorimotor robotic platform learning in cerebellum-driven movement tasks through a cerebellar realistic model
Ijcci 2013 Proceedings of the 5th International Joint Conference on Computational Intelligence, 2013
Distributed cerebellar plasticity implements adaptable gain control in a manipulation task: A closed-loop robotic simulation
Jesús A. Garrido, Niceto R. Luque, Egidio D'Angelo, Eduardo Ros
Frontiers in Neural Circuits, 2013
Cerebellar theta burst stimulation modulates short latency afferent inhibition in Alzheimer's disease patients
Francesco Di Lorenzo, Alessandro Martorana, Viviana Ponzo, Sonia Bonnì, Egidio D'Angelo, Carlo Caltagirone, Giacomo Koch
Frontiers in Aging Neuroscience, 2013
Granule cell ascending axon excitatory synapses onto Golgi cells implement a potent feedback circuit in the cerebellar granular layer
E. Cesana, K. Pietrajtis, C. Bidoret, P. Isope, E. D'Angelo, S. Dieudonne, L. Forti
Journal of Neuroscience, 2013
Foreword
Functional Neurology, 2013
Gating of Long-Term Potentiation by Nicotinic Acetylcholine Receptors at the Cerebellum Input Stage
Francesca Prestori, Claudia Bonardi, Lisa Mapelli, Paola Lombardo, Rianne Goselink, Maria Egle De Stefano, Daniela Gandolfi, Jonathan Mapelli, Daniel Bertrand, Martijn Schonewille, Chris De Zeeuw, Egidio D’Angelo
Plos One, 2013
Spike timing regulation on the millisecond scale by distributed synaptic plasticity at the cerebellum input stage: A simulation study
Jesús A. Garrido, Eduardo Ros, Egidio D’Angelo
Frontiers in Computational Neuroscience, 2013
The cerebellar Golgi cell and spatiotemporal organization of granular layer activity
Egidio D'Angelo, Sergio Solinas, Jonathan Mapelli, Daniela Gandolfi, Lisa Mapelli, Francesca Prestori
Frontiers in Neural Circuits, 2013
Silencing the Majority of Cerebellar Granule Cells Uncovers Their Essential Role in Motor Learning and Consolidation
Elisa Galliano, Zhenyu Gao, Martijn Schonewille, Boyan Todorov, Esther Simons, Andreea S. Pop, Egidio D’Angelo, Arn M.J.M. van den Maagdenberg, Freek E. Hoebeek, Chris I. De Zeeuw
Cell Reports, 2013
Theta-frequency resonance at the cerebellum input stage improves spike-timing on the millisecond time-scale
Daniela Gandolfi, Paola Lombardo, Jonathan Mapelli, Sergio Solinas, Egidio D’Angelo
Frontiers in Neural Circuits, 2013
Anatomical investigation of potential contacts between climbing fibers and cerebellar golgi cells in the mouse
Elisa Galliano, Marco Baratella, Martina Sgritta, Tom J. H. Ruigrok, Elize D. Haasdijk, Freek E. Hoebeek, Egidio D'Angelo, Dick Jaarsma, Chris I. De Zeeuw
Frontiers in Neural Circuits, 2013
Late-onset bursts evoked by mossy fibre bundle stimulation in unipolar brush cells: Evidence for the involvement of H- and TRP-currents
F. Locatelli, L. Bottà, F. Prestori, S. Masetto, E. D’Angelo
Journal of Physiology, 2013
Seeking a unified framework for cerebellar function and dysfunction: From circuit operations to cognition
Frontiers in Neural Circuits, 2013
Cerebellar granule cell
Egidio D’Angelo
Handbook of the Cerebellum and Cerebellar Disorders, 2013
MRI observation of hippocampal degeneration in Alzheimer's disease: A forgotten case
Functional Neurology, 2013
Neurophysiological Correlates of Musical Giftedness in Autism Spectrum Disorders
M. Boso, E. D'Angelo, F. Barale
Music Medicine, 2013
Brain-inspired Sensorimotor Robotic Platform: Learning in Cerebellum-driven Movement Tasks through a Cerebellar Realistic Model
Claudia Casellato, Jesús A. Garrido, Cristina Franchin, Giancarlo Ferrigno, Egidio D’Angelo, et al.
International Joint Conference on Computational Intelligence, 2013
Realistic modeling of neurons and networks: Towards brain simulation
Egidio D’Angelo, Sergio Solinas, Jesús A. Garrido, Claudia Casellato, Alessandra Pedrocchi, et al.
Functional Neurology, 2013
Seeking a unified framework for cerebellar function and dysfunction: From circuit operations to cognition
Egidio D'Angelo, Stefano Casali
Frontiers in Neural Circuits, 2012
Modeling spike-train processing in the cerebellum granular layer and changes in plasticity reveal single neuron effects in neural ensembles
Chaitanya Medini, Bipin Nair, Egidio D'Angelo, Giovanni Naldi, Shyam Diwakar
Computational Intelligence and Neuroscience, 2012
An integrated motor control loop of a human-like robotic arm: Feedforward, feedback and cerebellum-based learning
C. Casellato, A. Pedrocchi, J. A. Garrido, N. R. Luque, G. Ferrigno, E. D'Angelo, E. Ros
Proceedings of the IEEE Ras and EMBS International Conference on Biomedical Robotics and Biomechatronics, 2012
Toward the connectomic era
Functional Neurology, 2012
New trends in neuroscience: The challenge of functional neurology
Functional Neurology, 2012
The human brain project
Functional Neurology, 2012
Theta-burst stimulation of the cerebellum interferes with internal representations of sensory-motor information related to eye movements in humans
Silvia Colnaghi, Stefano Ramat, Egidio D’Angelo, Andrea Cortese, Giorgio Beltrami, Arrigo Moglia, Maurizio Versino
Cerebellum, 2011
Neural circuits of the cerebellum: Hypothesis for function
EGIDIO D'ANGELO
Journal of Integrative Neuroscience, 2011
Local field potential modeling predicts dense activation in cerebellar granule cells clusters under LTP and LTD control
Shyam Diwakar, Paola Lombardo, Sergio Solinas, Giovanni Naldi, Egidio D'Angelo
Plos One, 2011
The cerebellar network: Revisiting the critical issues
Egidio D’Angelo
Journal of Physiology, 2011
Realistic modeling of large-scale networks: Spatio-temporal dynamics and long-term synaptic plasticity in the cerebellum
Egidio D’Angelo, Sergio Solinas
Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2011
NR2A subunit of the N-methyl d-aspartate receptors are required for potentiation at the mossy fiber to granule cell synapse and vestibulo-cerebellar motor learning
C.E. Andreescu, F. Prestori, F. Brandalise, A. D'Errico, M.T.G. De Jeu, P. Rossi, L. Botta, G. Kohr, P. Perin, E. D'Angelo, C.I. De Zeeuw
Neuroscience, 2011
The cerebellar network: From structure to function and dynamics
E. D'Angelo, P. Mazzarello, F. Prestori, J. Mapelli, S. Solinas, P. Lombardo, E. Cesana, D. Gandolfi, L. Congi
Brain Research Reviews, 2011
A modeling based study on the origin and nature of evoked post-synaptic local field potentials in granular layer
Harilal Parasuram, Bipin Nair, Giovanni Naldi, Egidio D’Angelo, Shyam Diwakar
Journal of Physiology Paris, 2011
Complex dynamics in the granual layer of the cerebellum: Large-scale computational reconstructions
4th International Conference on Cognitive Systems Cogsys 2010, 2010
Rebuilding cerebellar network computations from cellular neurophysiology
Egidio D'Angelo
Frontiers in Cellular Neuroscience, 2010
Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2
Joanna Giza, Michael J. Urbanski, Francesca Prestori, Bhaswati Bandyopadhyay, Annie Yam, Victor Friedrich, Kevin Kelley, Egidio D'Angelo, Mitchell Goldfarb
Journal of Neuroscience, 2010
Discovery and rediscoveries of Golgi cells
Elisa Galliano, Paolo Mazzarello, Egidio D’Angelo
Journal of Physiology, 2010
Long-term inactivation particle for voltage-gated sodium channels
Katarzyna Dover, Sergio Solinas, Egidio D’Angelo, Mitchell Goldfarb
Journal of Physiology, 2010
How synaptic release probability shapes neuronal transmission: Information-theoretic analysis in a cerebellar granule cell
Angelo Arleo, Thierry Nieus, Michele Bezzi, Anna D'Errico, Egidio D'Angelo, Olivier J.-M. D. Coenen
Neural Computation, 2010
Neuronal circuit function and dysfunction in the cerebellum: From neurons to integrated control
Functional Neurology, 2010
Transcranial magnetic stimulation over the cerebellum and eye movements: State of the art
Functional Neurology, 2010
High-pass filtering and dynamic gain regulation enhance vertical bursts transmission along the mossy fiber pathway of cerebellum
Jonathan Mapelli
Frontiers in Cellular Neuroscience, 2010
A realistic large-scale model of the cerebellum granular layer predicts circuit spatio-temporal filtering properties
Solinas
Frontiers in Cellular Neuroscience, 2010
Brain plasticity and functionality explored by nonlinear optical microscopy
L. Sacconi, L. Allegra, M. Buffelli, P. Cesare, E. D'Angelo, D. Gandolfi, G. Grasselli, J. Lotti, J. Mapelli, P. Strata, F. S. Pavone
Proceedings of SPIE the International Society for Optical Engineering, 2010
Homeostasis of intrinsic excitability: Making the point
Egidio D’Angelo
Journal of Physiology, 2010
Combinatorial responses controlled by synaptic inhibition in the cerebellum granular layer
Jonathan Mapelli, Daniela Gandolfi, Egidio D'Angelo
Journal of Neurophysiology, 2010
Autism and genius: Is there a link? The involvement of central brain loops and hypotheses for functional testing
Functional Neurology, 2010
The critical role of Golgi cells in regulating spatio-temporal integration and plasticity at the cerebellum input stage
Egidio D'Angelo
Frontiers in Neuroscience, 2009
Differential induction of bidirectional long-term changes in neurotransmitter release by frequency-coded patterns at the cerebellar input
Anna D’Errico, Francesca Prestori, Egidio D'Angelo
Journal of Physiology, 2009
Timing in the cerebellum: oscillations and resonance in the granular layer
E. D'Angelo, S.K.E. Koekkoek, P. Lombardo, S. Solinas, E. Ros, J. Garrido, M. Schonewille, C.I. De Zeeuw
Neuroscience, 2009
Action potential detection by non linear microscopy
Leonardo Sacconi, Jacopo Lotti, Rodney P. O’Connor, Jonathan Mapelli, Daniela Gandolfi, Egidio D'Angelo, Francesco S. Pavone
Progress in Biomedical Optics and Imaging Proceedings of SPIE, 2009
Tonic activation of GABAB receptors reduces release probability at inhibitory connections in the cerebellar glomerulus
Lisa Mapelli, Paola Rossi, Thierry Nieus, Egidio D'Angelo
Journal of Neurophysiology, 2009
Cognitive memory control in borderline personality disorder patients
M. Sala, E. Caverzasi, E. Marraffini, G. De Vidovich, M. Lazzaretti, G. d'Allio, M. Isola, M. Balestrieri, E. D'Angelo, F. Zappoli Thyrion, P. Scagnelli, F. Barale, P. Brambilla
Psychological Medicine, 2009
Axonal Na+ channels ensure fast spike activation and back-propagation in cerebellar granule cells
Shyam Diwakar, Jacopo Magistretti, Mitchell Goldfarb, Giovanni Naldi, Egidio D'Angelo
Journal of Neurophysiology, 2009
Timing and plasticity in the cerebellum: focus on the granular layer
Egidio D’Angelo, Chris I. De Zeeuw
Trends in Neurosciences, 2009
Imaging of cell and neural circuit activity
Confinia Cephalalgica, 2008
Non-invasive imaging of brain structure and function in neural connectivity analysis
Functional Neurology, 2008
Optical recording of electrical activity in intact neuronal networks with random access second-harmonic generation microscopy
Brett W. Garner, Tong Cai, Zhibing Hu, Arup Neogi
Optics Express, 2008
Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control
Francesca Prestori, Paola Rossi, Bertrand Bearzatto, Jeanne Lainé, Daniela Necchi, Shyam Diwakar, Serge N. Schiffmann, Herbert Axelrad, Egidio D'Angelo
Journal of Neuroscience, 2008
Tactile stimulation evokes long-term synaptic plasticity in the granular layer of cerebellum
L. Roggeri, B. Rivieccio, P. Rossi, E. D'Angelo
Journal of Neuroscience, 2008
Event-driven simulation of cerebellar granule cells
Richard R. Carrillo, Eduardo Ros, Silvia Tolu, Thierry Nieus, Egidio D’Angelo
Biosystems, 2008
Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar golgi cells
Solinas
Frontiers in Cellular Neuroscience, 2007
Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar Golgi cells: Simulations of their impact in vivo
Sergio Solinas
Frontiers in Cellular Neuroscience, 2007
Fibroblast Growth Factor Homologous Factors Control Neuronal Excitability through Modulation of Voltage-Gated Sodium Channels
Mitchell Goldfarb, Jon Schoorlemmer, Anthony Williams, Shyam Diwakar, Qing Wang, Xiao Huang, Joanna Giza, Dafna Tchetchik, Kevin Kelley, Ana Vega, Gary Matthews, Paola Rossi, David M. Ornitz, Egidio D'Angelo
Neuron, 2007
The spatial organization of long-term synaptic plasticity at the input stage of cerebellum
Jonathan Mapelli, Egidio D'Angelo
Journal of Neuroscience, 2007
The synapsin domain E accelerates the exo-endocytotic cycle of synaptic vesicles in cerebellar Purkinje cells
Anna Fassio, Daniela Merlo, Jonathan Mapelli, Andrea Menegon, Anna Corradi, Maurizio Mete, Simona Zappettini, Giambattista Bonanno, Flavia Valtorta, Egidio D'Angelo, Fabio Benfenati
Journal of Cell Science, 2006
Increased Ethanol Resistance and Consumption in Eps8 Knockout Mice Correlates with Altered Actin Dynamics
Nina Offenhäuser, Daniela Castelletti, Lisa Mapelli, Blanche Ekalle Soppo, Maria Cristina Regondi, Paola Rossi, Egidio D'Angelo, Carolina Frassoni, Alida Amadeo, Arianna Tocchetti, Benedetta Pozzi, Andrea Disanza, Douglas Guarnieri, Christer Betsholtz, Giorgio Scita, Ulrike Heberlein, Pier Paolo Di Fiore
Cell, 2006
Inhibition of constitutive inward rectifier currents in cerebellar granule cells by pharmacological and synaptic activation of GABAB receptors
Paola Rossi, Lisa Mapelli, Leda Roggeri, David Gall, Alban De Kerchove d'Exaerde, Serge N. Schiffmann, Vanni Taglietti, Egidio D'Angelo
European Journal of Neuroscience, 2006
Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: An electrophysiological and modelling study
Jacopo Magistretti, Loretta Castelli, Lia Forti, Egidio D'Angelo
Journal of Physiology, 2006
LTP regulates burst initiation and frequency at mossy fiber-granule cell synapses of rat cerebellum: Experimental observations and theoretical predictions
Thierry Nieus, Elisabetta Sola, Jonathan Mapelli, Elena Saftenku, Paola Rossi, Egidio D'Angelo
Journal of Neurophysiology, 2006
Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells
Lia Forti Elisabetta Cesana, Jonathan Mapelli, Egidio D'Angelo
Journal of Physiology, 2006
Intracellular calcium regulation by burst discharge determines bidirectional long-term synaptic plasticity at the cerebellum input stage
David Gall, Francesca Prestori, Elisabetta Sola, Anna D'Errico, Celine Roussel, Lia Forti, Paola Rossi, Egidio D'Angelo
Journal of Neuroscience, 2005
Synaptic plasticity at the cerebellum input stage: Mechanisms and functional implications
Archives Italiennes De Biologie, 2005
Modeling synaptic transmission and quantifying information transfer in the granular layer of the cerebellum
Egidio D’Angelo, Thierry Nieus, Michele Bezzi, Angelo Arleo, Olivier J. -M. D. Coenen
Lecture Notes in Computer Science, 2005
Long-term potentiation of synaptic transmission at the mossy fiber-granule cell relay of cerebellum
Egidio D’Angelo, Paola Rossi, David Gall, Francesca Prestori, Thierry Nieus, Arianna Maffei, Elisabetta Sola
Progress in Brain Research, 2005
Role of calcium binding proteins in the control of cerebellar granule cell neuronal excitability: Experimental and modeling studies
D. Gall, C. Roussel, T. Nieus, G. Cheron, L. Servais, E. D’Angelo, S.N. Schiffmann
Progress in Brain Research, 2005
Increased neurotransmitter release during long-term potentiation at mossy fibre-granule cell synapses in rat cerebellum
Elisabetta Sola, Francesca Prestori, Paola Rossi, Vanni Taglietti, Egidio D'Angelo
Journal of Physiology, 2004
An integrate-and-fire model of a cerebellar granule cell
Michele Bezzi, Thierry Nieus, Olivier J.-M. Coenen, Egidio D'Angelo
Neurocomputing, 2004
Altered Neuronal Excitability in Cerebellar Granule Cells of Mice Lacking Calretinin
David Gall, Céline Roussel, Isabella Susa, Egidio D'Angelo, Paola Rossi, Bertrand Bearzatto, Marie Christine Galas, David Blum, Stéphane Schurmans, Serge N. Schiffmann
Journal of Neuroscience, 2003
NO enhances presynaptic currents during cerebellar mossy fiber - Granule cell LTP
Arianna Maffei, Francesca Prestori, Katsuei Shibuki, Paola Rossi, Vanni Taglietti, Egidio D'Angelo
Journal of Neurophysiology, 2003
NMDA receptor 2 (NR2) C-terminal control of NR open probability regulates synaptic transmission and plasticity at a cerebellar synapse
Paola Rossi, Elisabetta Sola, Vanni Taglietti, Thilo Borchardt, Frank Steigerwald, Jo Kristian Utvik, Ole Petter Ottersen, Georg Köhr, Egidio D'Angelo
Journal of Neuroscience, 2002
Presynaptic current changes at the mossy fiber-granule cell synapse of cerebellum during LTP
Arianna Maffei, Francesca Prestori, Paola Rossi, Vanni Taglietti, Egidio D'Angelo
Journal of Neurophysiology, 2002
Beyond parallel fiber LTD: The diversity of synaptic and non-synaptic plasticity in the cerebellum
Christian Hansel, David J. Linden, Egidio D'Angelo
Nature Neuroscience, 2001
Theta-frequency bursting and resonance in cerebellar granule cells: Experimental evidence and modeling of a slow K+-dependent mechanism
Egidio D'Angelo, Thierry Nieus, Arianna Maffei, Simona Armano, Paola Rossi, Vanni Taglietti, Andrea Fontana, Giovanni Naldi
Journal of Neuroscience, 2001
Long-term potentiation of intrinsic excitability at the mossy fibergranule cell synapse of rat cerebellum
S. Armano, P. Rossi, V. Taglietti, E. D'Angelo
Journal of Neuroscience, 2000
Evidence for NMDA and mGLU receptor-dependent long-term potentiation of mossy fiber-granule cell transmission in rat cerebellum
Egidio D'Angelo, Paola Rossi, Simona Armano, Vanni Taglietti
Journal of Neurophysiology, 1999
The weaver mutation causes a loss of inward rectifier current regulation in premigratory granule cells of the mouse cerebellum
Paola Rossi, Giovanna De Filippi, Simona Armano, Vanni Taglietti, Egidio D’Angelo
Journal of Neuroscience, 1998
Integrated regulation of signal coding and plasticity by NMDA receptors at a central synapse
Egidio D′Angelo, Paola Rossi
Neural Plasticity, 1998
Ionic mechanism of electroresponsiveness in cerebellar granule cells implicates the action of a persistent sodium current
Egidio D'Angelo, Giovanna De Filippi, Paola Rossi, Vanni Taglietti
Journal of Neurophysiology, 1998
Synaptic activation of Ca2+ action potentials in immature rat cerebellar granule cells in situ
Egidio D'Angelo, Giovanna De Filippi, Paola Rossi, Vanni Taglietti
Journal of Neurophysiology, 1997
Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors.
E D'Angelo, G De Filippi, P Rossi, V Taglietti
Journal of Physiology, 1995
Miniature Endplate Current Kinetics at the Mouse Neuromuscular Junction: Effects of Temperature and Medium Viscosity
Franco Tanzi, Egidio D'Angelo
European Journal of Neuroscience, 1995
Age-dependent expression of high-voltage activated calcium currents during cerebellar granule cell development in situ
Paola Rossi, Egidio D'Angelo, Jacopo Magistretti, Mauro Toselli, Vanni Taglietti
Pflugers Archiv, 1994
Voltage‐dependent Kinetics of N‐Methyl‐d‐aspartate Synaptic Currents in Rat Cerebellar Granule Cells
Egidio D'Angelo, Paola Rossi, Vanni Taglietti
European Journal of Neuroscience, 1994
The relationship between synaptogenesis and expression of voltage-dependent currents in cerebellar granule cells in situ
E. D'Angelo, P. Rossi, G. De Filippi, J. Magistretti, V. Taglietti
Journal of Physiology Paris, 1994
Different proportions of N-methyl-d-aspartate and non-N-methyl-d-aspartate receptor currents at the mossy fibre-granule cell synapse of developing rat cerebellum
E. D'Angelo, P. Rossi, V. Taglietti
Neuroscience, 1993
A mathematical model of potential spreading along neuron dendrites of cerebellar granule cells
V. Comincioli, D. Funaro, A. Torelli, E. D'Angelo, P. Rossi
Applied Mathematics and Computation, 1993
Glutamate metabolism, release, and quantal transmission at central excitatory synapses: Implications for neural plasticity
Functional Neurology, 1992
Synaptic mechanisms in long-term potentiation
Functional Neurology, 1992
Excitatory amino acid regulation of neuronal functions
Functional Neurology, 1992
Protein Kinase C Facilitation of Acetylcholine Release at the Rat Neuromuscular Junction
Egidio D'Angelo, Paola Rossi, Franco Tanzi, Vanni Taglietti
European Journal of Neuroscience, 1992
Dual-component NMDA receptor currents at a single central synapse
E. D'Angelo, P. Rossi, J. Garthwaite
Nature, 1990
Calcium-dependent chloride transient currents in the immature oocyte of the frog, Rana esculenta
Archives Italiennes De Biologie, 1989

Egidio Ugo D'Angelo

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