A Dual-Mode On-Chip 3D-Printed Nanoengineered Platform for Extraction and Electrochemical Detection of Enrofloxacin Supratim Mahapatra, Ankur Singh, Ratul Paul, Pranjal Chandra Small, 2025 A magnetic molecularly imprinted polymer (MMIP) is synthesized for the development of a highly selective and sensitive electrochemical sensing platform targeting enrofloxacin (ENF). The micro‐sized mesoporous core‐shell MMIP structure is constructed with a magnetite core and an outer shell functionalized using 3‐aminopropyltriethoxysilane (APTES) as the monomer. The synthesis is optimized and validated using a range of physical and electrochemical techniques. The sensor is designed with dual‐mode functionality, integrating magnetic separation for efficient target extraction and electrochemical detection for precise quantification. A conventional electrode is modulated with multi‐layer nano‐functionalization to improve its analytical performance, while 3D‐printed components ensure miniaturization, fabrication precision, and scalability. The resulting device exhibits a broad linear detection range from 100 pM to 10 mM (10−10 to 10−2 M), with an exceptionally low limit of detection (LOD) of 161 fM (1.61 × 10−13 M). As ENF is recurrently administered to cattle, milk is used as a real sample to demonstrate the sensor's proof‐of‐application. Real sample analysis showed a high recovery rate (90.23% to 97.29%) with minimal matrix interference, confirming reliability in complex biological matrices. The platform demonstrates exceptional reproducibility and stability, offering a robust and scalable solution for environmental and food safety monitoring.
Molecularly imprinted polymers as emerging engineered platforms for precision molecular sensing A Singh, S Mahapatra, SK Singh, P Chandra Biomaterials Science , 2026 2026 Citations: 3
3D tetrametallic dendrite-based non-enzymatic sensor coupled with a smartphone interface for GSH quantification in biological fluids and ex vivo rat models R Kumari, S Mahapatra, O Ummadisetty, V Tiwari, P Chandra ACS Applied Materials & Interfaces 17 (39), 54466-54483 , 2025 2025 Citations: 6
Metallic nanoparticle-based glassy carbon electrodes for smart biosensing S Mahapatra, DS Dkhar, A Singh, P Chandra Current Opinion in Electrochemistry, 101748 , 2025 2025 Citations: 2
Laser-scribed micro/nanostructures modified surfaces for electrochemical sensors: from fundamentals to applications S Mahapatra, R Kumari, DS Dkhar, A Singh, P Chandra TrAC Trends in Analytical Chemistry, 118407 , 2025 2025 Citations: 7
A Dual‐Mode On‐Chip 3D‐Printed Nanoengineered Platform for Extraction and Electrochemical Detection of Enrofloxacin S Mahapatra, A Singh, R Paul, P Chandra Small 21 (33), 2502880 , 2025 2025 Citations: 8
Optoelectronic MXene quantum dots: frontiers in sensor technology for next-generation diagnostics and environmental monitoring A Singh, S Mahapatra, R Prasad, SK Singh, P Chandra Nanoscale 17, 15554-15591 , 2025 2025 Citations: 32
An electrochemically charged nanoengineered bioelectronic immunosensing device for osteopontin detection in serum samples DS Dkhar, S Mahapatra, P Chandra Nanoscale 17, 13668-13684 , 2025 2025 Citations: 5
Ni/Co stacked metal–organic framework-based nanoelectronic device integrated with smartphone for real-time nitrite sensing Shubhangi, R Kumari, AJ Ghosh, S Mahapatra, SK Rai, P Chandra ACS Applied Electronic Materials 7 (10), 4457-4471 , 2025 2025 Citations: 5
A Laser-Directed Multi-Functional Electrochemical Paper-Based Sensor and A Method of Fabrication Thereof S Mahapatra, R Kumari, P Chandra IN Patent 564,192 , 2025 2025
Fabrication of a laser-directed electrochemical paper analytical device and its deployment for multi-functional electrochemical sensing S Mahapatra, R Kumari, P Chandra Chemical Engineering Journal 486, 150232 , 2024 2024 Citations: 13
A portable colorimetry sensing device for point of care diagnostics S Mahapatra, A Thakur, P Chandra IN Patent 521,579 , 2024 2024
Printed circuit boards: system automation and alternative matrix for biosensing S Mahapatra, R Kumari, P Chandra Trends in Biotechnology 41 (12) , 2023 2023 Citations: 16
Decision-Making Software-Integrated Ultrafast Detection of Lead in Surface Water Using a Chemo-Nano Sensing Device S Mahapatra, P Chandra ACS Sustainable Chemistry & Engineering , 2023 2023 Citations: 16
Engineered nanomaterial based implantable MicroNanoelectrode for in vivo Analysis: Technological advancement and commercial aspects MG Dastidar, S Mahapatra, R Kumari, DS Dkhar, S Roy, P Chandra Microchemical Journal 187, 108431 , 2023 2023 Citations: 8
Development of a palm-sized bioelectronic sensing device for protein detection in milk samples S Mahapatra, P Chandra International Journal of Biological Macromolecules 230, 123132 , 2023 2023 Citations: 8
Engineering design, implementation, and sensing mechanisms of wearable bioelectronic sensors in clinical settings DS Dkhar, R Kumari, S Mahapatra, Divya, P Chandra Electroanalysis 35 (2), e202200154 , 2023 2023 Citations: 17
Drug encapsulated lipid-polymeric nanohybrid as a chemo-therapeutic platform of cancer R Kumar, VR Srivastava, S Mahapatra, DS Dkhar, R Kumari, K Prerna, ... Nanotheranostics 7 (2), 167 , 2023 2023 Citations: 15
Design and engineering of a palm-sized optical immunosensing device for the detection of a kidney dysfunction biomarker Divya, S Mahapatra, P Chandra Biosensors 12 (12), 1118 , 2022 2022 Citations: 11
Nano-engineered surface comprising metallic dendrites for biomolecular analysis in clinical perspective R Kumari, DS Dkhar, S Mahapatra, Divya, SP Singh, P Chandra Biosensors 12 (12), 1062 , 2022 2022 Citations: 21
Ligand conjugated lipid‐based nanocarriers for cancer theranostics R Kumar, DS Dkhar, R Kumari, Divya, S Mahapatra, A Srivastava, ... Biotechnology and bioengineering 119 (11), 3022-3043 , 2022 2022 Citations: 42
MOST CITED SCHOLAR PUBLICATIONS
Amelioration of diabetic nephropathy using pomegranate peel extract-stabilized gold nanoparticles: assessment of NF-κB and Nrf2 signaling system K Manna, S Mishra, M Saha, S Mahapatra, C Saha, G Yenge, N Gaikwad, ... International journal of nanomedicine, 1753-1777 , 2019 2019 Citations: 134
Clinically practiced and commercially viable nanobio engineered analytical methods for COVID-19 diagnosis S Mahapatra, P Chandra Biosensors and Bioelectronics 165, 112361 , 2020 2020 Citations: 117
Green Approach To Synthesize Crystalline Nanoscale Zn II -Coordination Polymers: Cell Growth Inhibition and Immunofluorescence Study S Mukherjee, S Ganguly, K Manna, S Mondal, S Mahapatra, D Das Inorganic Chemistry 57 (7), 4050-4060 , 2018 2018 Citations: 109
Lipid based nanocarriers: Production techniques, concepts, and commercialization aspect R Kumar, DS Dkhar, R Kumari, S Mahapatra, VK Dubey, P Chandra Journal of Drug Delivery Science and Technology 74, 103526 , 2022 2022 Citations: 85
A new triazine based π-conjugated mesoporous 2D covalent organic framework: its in vitro anticancer activities SK Das, S Mishra, K Manna, U Kayal, S Mahapatra, KD Saha, S Dalapati, ... Chemical Communications 54 (81), 11475-11478 , 2018 2018 Citations: 75
Natural habitat, phytochemistry and pharmacological properties of a medicinal weed–Cleome rutidosperma DC.(Cleomaceae): A comprehensive review P Ghosh, S Chatterjee, P Das, S Karmakar, S Mahapatra International Journal of Pharmaceutical Sciences and Research 10 (4), 1605-1612 , 2019 2019 Citations: 63
Morphological characteristics and Phyto-pharmacological detailing of Hatishur (Heliotropium indicum Linn.): A concise review P Ghosh, P Das, C Das, S Mahapatra, S Chatterjee Journal of Pharmacognosy and Phytochemistry 7 (5), 1900-1907 , 2018 2018 Citations: 59
Ultrasensitive aptasensors for the detection of viruses based on opto-electrochemical readout systems Divya, DS Dkhar, R Kumari, S Mahapatra, R Kumar, P Chandra Biosensors 12 (2), 81 , 2022 2022 Citations: 55
Nanobioengineered sensing technologies based on cellulose matrices for detection of small molecules, macromolecules, and cells Divya, S Mahapatra, VR Srivastava, P Chandra Biosensors 11 (6), 168 , 2021 2021 Citations: 53
Marine biological macromolecules as matrix material for biosensor fabrication N Bedi, DK Srivastava, A Srivastava, S Mahapatra, DS Dkhar, P Chandra, ... Biotechnology and bioengineering 119 (8), 2046-2063 , 2022 2022 Citations: 44
Ligand conjugated lipid‐based nanocarriers for cancer theranostics R Kumar, DS Dkhar, R Kumari, Divya, S Mahapatra, A Srivastava, ... Biotechnology and bioengineering 119 (11), 3022-3043 , 2022 2022 Citations: 42
Antibody-receptor bioengineering and its implications in designing bioelectronic devices DS Dkhar, R Kumari, S Mahapatra, R Kumar, T Tripathi, P Chandra International journal of biological macromolecules 218, 225-242 , 2022 2022 Citations: 41
Ultra-sensitive detection of tizanidine in commercial tablets and urine samples using zinc oxide coated glassy carbon electrode LS Killedar, MM Shanbhag, SJ Malode, GB Bagihalli, S Mahapatra, ... Microchemical Journal 172, 106956 , 2022 2022 Citations: 33
Optoelectronic MXene quantum dots: frontiers in sensor technology for next-generation diagnostics and environmental monitoring A Singh, S Mahapatra, R Prasad, SK Singh, P Chandra Nanoscale 17, 15554-15591 , 2025 2025 Citations: 32
Nano-bioengineered sensing technologies for real-time monitoring of reactive oxygen species in in vitro and in vivo models R Kumari, DS Dkhar, S Mahapatra, R Kumar, P Chandra Microchemical Journal 180, 107615 , 2022 2022 Citations: 32
Amberlite XAD-4 based electrochemical sensor for diclofenac detection in urine and commercial tablets MM Shanbhag, D Ilager, S Mahapatra, NP Shetti, P Chandra Materials Chemistry and Physics 273, 125044 , 2021 2021 Citations: 31
Nanomaterial functionalization strategies in bio-interface development for modern diagnostic devices K Mahato, A Kumar, B Purohit, S Mahapatra, A Srivastava, P Chandra Biointerface engineering: prospects in medical diagnostics and drug delivery … , 2020 2020 Citations: 30
N-acetyl-d-glucosamine decorated nano-lipid-based carriers as theranostics module for targeted anti-cancer drug delivery R Kumar, S Mahapatra, VK Dubey, P Chandra Materials Chemistry and Physics 282, 125956 , 2022 2022 Citations: 22
Nano-engineered surface comprising metallic dendrites for biomolecular analysis in clinical perspective R Kumari, DS Dkhar, S Mahapatra, Divya, SP Singh, P Chandra Biosensors 12 (12), 1062 , 2022 2022 Citations: 21
Advanced biosensing methodologies for ultrasensitive detection of human coronaviruses S Mahapatra, A Baranwal, B Purohit, S Roy, SK Mahto, P Chandra Diagnostic strategies for COVID-19 and other coronaviruses, 19-36 , 2020 2020 Citations: 21