Sandip B Dhobale
@dypatil.edu/engineering
Assistant Professor, Engineering Sciences
Assistant Professor
EDUCATION
PhD from Pune Uniersity
RESEARCH INTERESTS
Applied Physics, Nanomaterials and their sensing and energy applications.
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Gajendrasingh Y. Rajput, Manoj S. Gofane, and Sandip Dhobale
Springer Singapore
Vaishali Rawat, Sandip Dhobale, and S. N. Kale
AIP Publishing
An extremely compact metamaterial microstrip sensor based on complementary split-ring-resonators (CSRRs) has been fabricated for chemical sensing. This device exhibits a resonance with high rejection at 4.5 GHz, which demonstrates concomitant variations when exposed to liquids of various permittivity values. The resonance frequency of CSRR is sensitive to the change in nearby dielectric material. The sensing of petrol shows a shift in frequency with a sharp dip in transmission, while, with ethanol, the frequency shift is accompanied with increase in the power of the signal. The ultra-fast reversibility and repeatability offers good headway towards hybrid fuel sensing applications.
Anupama Joshi, Rajashree Nori, Sandip Dhobale, V. Ramgopal Rao, S.N. Kale, and Suwarna Datar
Elsevier BV
Rohini Kitture, Sandip Dhobale, and S. N. Kale
Springer India
G.B. Deore, A.S. Limaye, Y.A. Dushing, S.B. Dhobale, S. Kale, and S.L. Laware
Science Alert
The problem of metalnutrient deficiency is becoming more serious with the introduction of modern agricultural practices. As a result, metalnutrient deficiency is recognized as one of the critical yield limiting factors. Metalnutrients are generally offered in their sulphate or oxide forms. However, it is reported that organically bound minerals generally have a higher bioavailability than inorganic minerals. Chelation makes otherwise unavailable metalnutrients plant available. Amino acids are well known among various chelating agents. In present investigation the fungus Paecilomyces variotii PR-4 was isolated from soil and was used for production of protease and determination of its activity. Proteins from germinating seeds of chick pea, mung bean, soybean and cowpea were hydrolyzed for the production of amino acids. Amino acids were recovered, estimated and utilized for chelation of metalnutrients viz., Zn, Cu, Fe, Mn, Mg, B and Mo. The resultant chelates were employed to detect with Fourier Transform Infra-Red Spectrophotometer (FTIR) analysis. The peaks of most intensive bands in the IR spectra of ligands recorded were present in the intervals of the wave numbers 3500-3300 and 1720-1700 cm(-1). Chelation of metalnutrients led to the broadening of peak and changes of the peak position of hydroxyl groups, which indicated the binding of the carboxylic groups and primary amine groups of amino acids to the metalnutrients. The resultant amino acids-metalnutrient chelates can be utilized as organic fertilizer.
Sandip Dhobale, N. M. Kulkarni, R. J. Choudhary, D. M. Phase, and S. N. Kale
American Scientific Publishers
S. N. Kale, J. Mona, Sandip Dhobale, Trupti Thite, and S. L. Laware
Wiley
Therapeutic agents or agricultural fertilizers captured in polymer colloids (PCs) give rise to interesting applications, which are typically related to sustained release. We synthesized crosslinked polymer structures with poly(vinyl alcohol) (PVA) and borax precursors. Fourier transform infrared spectroscopy showed that a polymer–boron ion complex was formed with the crosslinking reaction at the OH site of PVA; thereby, PCs were formed. Field-emission scanning electron microscopy showed that a uniform mesoporous two-dimensional structure formed via intermolecular and intramolecular crosslinking. Trypsin enzyme and phosphate fertilizer were trapped in these PCs independently to study sustained release. Fertilizer-incorporated PCs were mixed with soil samples, in which seeds of fenugreek were sown, and the plant growth was monitored a duration of 15 days. The fertilizer release, studied with UV–visible spectroscopy, showed a sustained signature of the fertilizer (at 690 nm) in the water extracts of soil, with much healthier plant growth compared to the control. For the trypsin-incorporated PC samples, the released enzyme was made to interact with bovine serum albumin protein to monitor the released percentage with UV absorption spectroscopy. A systematic increase in the enzyme signature (at 280 nm) was observed for a duration of 60 min; this indicated the potential of PC for sustained drug release. The swelling calculations predicted that the mechanism involved was composed of pseudo-swelling behavior. We envisaged that the hydroxyl groups of the PC broke in water and formed a complex with water. This complex slowly dissolved in water to release the entrapped molecules. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
S. Dhobale, P. Joshee, G. Deore, S. L. Laware, and S. N. Kale
AIP Publishing
Polycrystalline rutile films of SnO2 (∼1500 A) were deposited on Al2O3. Film imaging showed regular ellipsoidal nanostructured growth. Different concentrations (1000–3000 U) of glucose oxidase (GOx) were immobilized on SnO2 surface. Upon interaction with various glucose concentrations (65–300 mg/dl), films showed pronounced change in their sheet resistance with recovery and repeatability. Nanostructured SnO2 surfaces probably enhance adsorption of oxygen moieties. These convert to their ions by extracting electron/s from the conduction band of SnO2, which further interacts with H+, formed during the GOx-glucose interaction. This releases the trapped electron to the conduction band of SnO2, justifying its role as a catalyst.
Sandip Dhobale, Trupti Thite, S. L. Laware, C. V. Rode, Soumya J. Koppikar, Ruchika-Kaul Ghanekar, and S. N. Kale
AIP Publishing
Amylase inhibitors, also known as starch blockers, contain substances that prevent dietary starches from being absorbed by the body via inhibiting breakdown of complex sugars to simpler ones. In this sense, these materials are projected as having potential applications in diabetes control. In this context, we report on zinc oxide nanoparticles as possible alpha-amylase inhibitors. Zinc oxide nanoparticles have been synthesized using soft-chemistry approach and 1-thioglycerol was used as a surfactant to yield polycrystalline nanoparticles of size ∼18 nm, stabilized in wurtzite structure. Conjugation study and structural characterization have been done using x-ray diffraction technique, Fourier transform infrared spectroscopy, UV-visible spectroscopy, and transmission electron microscopy. Cytotoxicity studies on human fibrosarcoma (HT-1080) and skin carcinoma (A-431) cell lines as well as mouse primary fibroblast cells demonstrate that up to a dose of 20 μg/ml, ZnO nanoparticles are nontoxic to the cells. W...