SAURABH SHARMA

@kalingauniversity.ac.in

ASSISTANT PROFESSOR, Faculty of Pharmacy
Kalinga University



              

https://researchid.co/saurabhjsg

RESEARCH INTERESTS

NOVEL DRUG DELIVERY SYSTEMS

3

Scopus Publications

11

Scholar Citations

2

Scholar h-index

Scopus Publications

  • Hydrogels as Potential Controlled Drug Delivery System: Drug Release Mechanism and Applications
    Sudhanshu Mishra, Smriti Ojha, and Saurabh Sharma

    Bentham Science Publishers Ltd.
    Abstract: Hydrogels are one of the most extensively studied novel drug delivery dosage forms owing to their satisfactory results in drug delivery in various conditions, including pain management, immunomodulation, carcinomas, healing of wounds, and cardiology. A crosslinked polymeric network and an optimum amount of water combine to form hydrogels. Due to their specific properties such as biocompatibility, biodegradability, hydrophilicity, and non-toxic to biological tissues, hydrogels are demanding biomaterials. Furthermore, due to their programmable physical characteristics, controlled degradation behavior, and capability to preserve unstable medicines from degradation, hydrogels serve as an advanced drug delivery system in which diverse physiochemical interactions with the polymeric matrix containing embedded medications control their release. Despite significant challenges remaining, there has been significant progress in recent years in overcoming the clinical and pharmacological constraints of hydrogels for drug delivery applications This review covers various hydrogel-forming polymers, strategies for crosslinking of gelling agents, and release mechanisms from the hydrogel. Moreover, the current work includes a few marketed hydrogel preparations and patent rights associated with it, describing its mechanism of action against the underlying diseases.

  • ADME Prediction, Structure-activity Relationship of Boswellic Acid Scaffold for the Aspect of Anticancer & Anti-inflammatory Potency
    Sudhanshu Mishra, Akhalesh Kumar, Saurabh Sharma, Smriti Ojha, and Pawan Upadhyay

    Bentham Science Publishers Ltd.
    Abstract: Nature is the chief source of various remedies which are used to cure various diseases. Boswellic acid (BA) is a secondary metabolite from the pentacyclic terpenoid compound groups that are derived from the plant genus Boswellia. The oleo gum resins of these plants are primarily composed of polysaccharides, with the remaining amounts of resin (30-60%) and essential oils (5-10%) soluble in organic solvents. BA and its analogs are also reported to exhibit various in vivo and biological responses for example anti-inflammatory, anti-tumor, free radical scavenging activity, etc. Among all analogs, 11-keto-β-boswellic acid (KBA) and 3-O-acetyl-11-keto-β-boswellic acid (AKBA) has been demonstrated to be the most effective at reducing cytokine production and inhibiting the inflammatory responsecausing enzymes. In this review, we summarized the computational ADME prediction via the SwissADME computational tool and the structure-activity relationship of the Boswellic acid scaffold for the aspect of anticancer and antiinflammatory potency. In addition to these research findings which are associated with the therapy of acute inflammation and some cancers, the potential of boswellic acids against other disorders was also discussed.


RECENT SCHOLAR PUBLICATIONS

  • ADME prediction, structure-activity relationship of boswellic acid scaffold for the aspect of anticancer & anti-inflammatory potency
    A Kumar, S Sharma, S Mishra, S Ojha, P Upadhyay
    Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal 2023

  • Pharmaceutical And Personal Care Product: A Major Threat to Aquatic Life
    D Kumar, S Sharma
    Journal of Survey in Fisheries Sciences 10 (4S), 2791-2804 2023

  • Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma
    SYSP Amrita Singh, Sudhanshu Mishra*, Saurabh Sharma, Smriti Ojha
    Current Cancer Drug Targets 23 (10) 2023

  • Hydrogels as Potential Controlled Drug Delivery System: Drug Release Mechanism and Applications
    SSSM Smriti Ojha
    Nanoscience & Nanotechnology-Asia 13 (6) 2023

  • APPROACH FOR A BIODEGRADABLE POLYMER FOR SANITARY NAPKINS
    DAH 1Saurabh Sharma*
    Journal of Pharmaceutical Negative Results 13 (7), 3572-3580 2022

  • Quantum Dots As A Novel Diagnostic Approach In Biomedical Imaging
    S Sharma
    Journal of Pharmaceutical Negative Results, 7760-7763 2022

  • RECENT APPROACHES IN GLUCOSE RESPONSIVE INSULIN DELIVERY SYSTEM
    SNDAS SAURABH SHARMA1*, ASHUTOSH KASHYAP2, PRASANTA KUMAR BISWAL1
    ASIAN JOURNAL OF PHARMACEUTICAL AND CLINICAL RESEARCH 15 (2), 18-29 2022

  • CURCUMIN AS A NATURAL APPROACH FOR TREATMENT OF ALZHEIMER’S DISEASE
    S Sharma, PK Biswal, V Pandey, A Kashyap
    2021

  • CURCUMIN AS A NATURAL APPROACH FOR TREATMENT OF ALZHEIMER’S DISEASE
    AK Saurabh Sharma*, Prasanta Kumar Biswal , Varsha Pandey
    https://www.wjpr.net/abstract_file/16822 2021

  • Data Protection in the Cloud: Dynamic Password Authentication and Certificate-Based Authorization
    S Sharma, A Verma, S Singh, V Pandey


  • ENERGY STORAGE SYSTEM FOR ELECTRIC VEHICLE
    S Sharma, V Pandey, S Malav, MG Srivastava


  • ANTIBIOTIC RESISTANCE IN AQUATIC BACTERIA: IMPLICATIONS FOR PUBLIC HEALTH AND ECOLOGICAL SYSTEMS
    K Kumar, S Sharma


MOST CITED SCHOLAR PUBLICATIONS

  • APPROACH FOR A BIODEGRADABLE POLYMER FOR SANITARY NAPKINS
    DAH 1Saurabh Sharma*
    Journal of Pharmaceutical Negative Results 13 (7), 3572-3580 2022
    Citations: 5

  • ADME prediction, structure-activity relationship of boswellic acid scaffold for the aspect of anticancer & anti-inflammatory potency
    A Kumar, S Sharma, S Mishra, S Ojha, P Upadhyay
    Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal 2023
    Citations: 2

  • Hydrogels as Potential Controlled Drug Delivery System: Drug Release Mechanism and Applications
    SSSM Smriti Ojha
    Nanoscience & Nanotechnology-Asia 13 (6) 2023
    Citations: 2

  • Pharmaceutical And Personal Care Product: A Major Threat to Aquatic Life
    D Kumar, S Sharma
    Journal of Survey in Fisheries Sciences 10 (4S), 2791-2804 2023
    Citations: 1

  • Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma
    SYSP Amrita Singh, Sudhanshu Mishra*, Saurabh Sharma, Smriti Ojha
    Current Cancer Drug Targets 23 (10) 2023
    Citations: 1