Peter Markus Spieth

Scopus Publications

Viscoelastic point-of-care testing for monitoring unfractionated heparin in critically ill patients: a prospective observational study comparing ClotPro® IN/HI-Test, aPTT and Anti-Xa activity
Martin Mirus, Anna Dietze, Oliver Tiebel, Jan Beyer-Westendorf, Oliver Grottke, et al.
BMC Anesthesiology, 2026
Effects of pneumatic tube systems on next-generation viscoelastic coagulation test devices in septic patients and healthy individuals: Results of the randomized controlled VETaPT trial
Martin Mirus, Erik Buehrer, Oliver Tiebel, Christian Schnabel, Jan Beyer-Westendorf, et al.
Scientific Reports, 2026
Rapid coagulation assessment is essential in critical care to enable timely correction of coagulopathy. Viscoelastic testing (VET) supports this goal but may be affected by mechanical stress during transport by pneumatic tube systems (PTS). As PTS are widely used to expedite sample delivery, evaluating the robustness of next-generation VET and platelet function assays under these conditions is crucial for reliable, time-sensitive diagnostics in intensive care. This study investigated the impact of PTS transport on VET and platelet function testing in healthy individuals and septic patients, including quantitative analysis of acceleration forces. This randomized trial applied a non-systematic sample-level allocation of paired blood samples from 46 healthy volunteers and 45 septic patients to manual and PTS transport. Acceleration was quantified via three-axis accelerometry. Samples were analyzed using ClotPro, ROTEM, TEG PlateletMapping, and Multiplate. Primary objective was the difference in test results following both transport modes. Analyses were performed on paired datasets (manual vs. PTS) per participant and assay. As pre-specified in the protocol, logistic regression modeled the probability of a clinically relevant EX-test clotting time (CT) change (≥ 10 s) within each cohort. Given the absence of associations, secondary equivalence analyses (TOST [two one-sided tests] and bootstrap) assessed whether observed effects were within pre-specified bounds. Neither logistic regression nor correlation analysis indicated an effect of mechanical stress on variable changes (all ρ 0.01). Across platforms, most viscoelastic and platelet function variables remained within predefined equivalence margins after PTS transport. Exceptions were TEG PlateletMapping HKH-R and, by bootstrap, ADP/AA-inhibition. In healthy volunteers, equivalence was confirmed for all variables (TOST p < 0.001). In septic patients, minor shifts remained within clinically acceptable limits, with equivalence confirmed for ClotPro IN-test CT (± 16s, p lower = 0.036; p upper < 0.001), EX-test MCF (± 2 mm, both p < 0.001), ROTEM INTEM CT (± 16s, both p < 0.001), Multiplate TRAP (± 10U, p lower = 0.001; p upper < 0.001), and TEG PlateletMapping ADP/AA inhibition (± 5%, both p < 0.05). Most next-generation viscoelastic and platelet assays are robust to PTS-induced stress. Coagulation diagnostics can include PTS transport without compromising validity. Only selected TEG PlateletMapping variables exhibited variability, indicating limited robustness. Trial registration: The study is retrospectively registered with the German Clinical Trials Register (DRKS00036231; https://drks.de/search/de/trial/DRKS00036231/details on 20.02.2025).
Depressive symptoms are a key determinant of health-related quality of life in ICU survivors with psychological distress
Robert Philipp Kosilek, Nora Schröder, Linda Sanftenberg, Daniela Lindemann, Antina Beutel, et al.
Scientific Reports, 2026
Survivors of critical illness frequently experience persistent impairments in health-related quality of life (HRQoL), with psychological symptoms contributing substantially to this burden. The relative contribution of co-occurring depression, anxiety, and post traumatic stress symptoms remains insufficiently understood. To address this gap, we conducted a cross-sectional analysis of pre-randomization data from the PICTURE randomized controlled trial, a multicenter study of a brief primary care–based psychological intervention for post-traumatic stress disorder symptoms following critical illness, including 319 intensive care unit survivors. Clinical, demographic, and mental health assessments were obtained after ICU discharge. Latent profile analysis, random forest modeling, and quantile regression were applied to identify determinants of HRQoL measured by the EuroQol Five-Dimension Five-Level (EQ-5D-5L) index and visual analog scale (VAS). The mean EQ-5D-5L index was 0.71 (SD 0.27; median 0.81) and the mean EQ VAS score was 60.7 (SD 19.4; median 60.0), indicating considerable overall impairment. Depression, anxiety, and post-traumatic stress symptoms showed substantial overlap and formed four distinct symptom profiles associated with specific functional impairments. Screening positive for depression on the 2-item Patient Health Questionnaire (PHQ-2) with ≥ 3 points was associated with a median reduction of -0.13 (95% CI -0.19 to -0.07) on the EQ-5D-5L index and -12.45 points (95% CI -17.93 to -6.96) on the EQ VAS, exceeding clinical and demographic predictors. These findings indicate that depressive symptoms are a major determinant of impaired health related quality of life among intensive care survivors with psychological distress and support routine brief depression screening in post-intensive care follow up. Trial registration: ClinTrials.gov: NCT03315390 (Registration date: 2017-10-20); German Clinical Trials Register: DRKS-ID: DRKS00012589 (Registration date: 2017-10-17).
Pulmonary complications following urological, gastrointestinal and gynaecological abdominal Surgery––A post-hoc analysis of an observational study in 29 countries
Tom D. Vermeulen, Sabrine N.T. Hemmes, Siebe Blok, Marcus J. Schultz, Michael Hiesmayr, et al.
Anaesthesia Critical Care and Pain Medicine, 2026
Hemodynamic monitoring: basic principles in operation room and intensive care unit
Martin Mirus, Bernd Saugel, Peter M. Spieth
Journal of Clinical Monitoring and Computing, 2026
Regional anesthesia under anticoagulation: Comparison of guidelines and recommendations for action
Simon-Friedrich Buhrmann, Lars Heubner, Oliver Vicent, Peter Markus Spieth
Schmerz, 2026
Outcome of Emergency Pulmonary Lobectomy under ECMO Support in Patients with COVID-19
Ana Beatriz Almeida, Michael Schweigert, Peter Spieth, Attila Dubecz, Marcelo Gama de Abreu, et al.
Thoracic and Cardiovascular Surgeon, 2026
Not much is known about the results of nonelective anatomical lung resections in coronavirus disease 2019 (COVID-19) patients put on extracorporeal membrane oxygenation (ECMO). The aim of this study was to analyze the outcome of lobectomy under ECMO support in patients with acute respiratory failure due to severe COVID-19. All COVID-19 patients undergoing anatomical lung resection with ECMO support at a German university hospital were included into a prospective database. Study period was April 1, 2020, to April 30, 2021 (first, second, and third waves in Germany). A total of nine patients (median age 61 years, interquartile range 10 years) were included. There was virtually no preexisting comorbidity (median Charlson score of comorbidity 0.2). The mean interval between first positive COVID-19 test and surgery was 21.9 days. Clinical symptoms at the time of surgery were sepsis (nine of nine), respiratory failure (nine of nine), acute renal failure (five of nine), pleural empyema (five of nine), lung artery embolism (four of nine), and pneumothorax (two of nine). Mean intensive care unit (ICU) and ECMO days before surgery were 15.4 and 6, respectively. Indications for surgery were bacterial superinfection with lung abscess formation and progressive septic shock (seven of nine) and abscess formation with massive pulmonary hemorrhage into the abscess cavity (two of nine). All patients were under venovenous ECMO with femoral-jugular configuration. Operative procedures were lobectomy (eight) and pneumonectomy (one). Weaning from ECMO was successful in four of nine. In-hospital mortality was five of nine. Mean total ECMO days were 10.3 ± 6.2 and mean total ICU days were 27.7 ± 9.9. Mean length of stay was 28.7 ± 8.8 days. Emergency surgery under ECMO support seems to open up a perspective for surgical source control in COVID-19 patients with bacterial superinfection and localized pulmonary abscess.
Putative anaphylactic shock during insertion of a double J ureteral stent
Dorothea Heisig, Peter Spieth, Torsten Richter
Anaesthesiologie, 2026
A YEAR IN REVIEW IN Minerva Anestesiologica 2025. ANESTHESIA, ANALGESIA, AND PERIOPERATIVE MEDICINE
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Luca BRAZZI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2026
Defining the bellwether procedures and processes for global trauma care: an international Delphi study
Michael F Bath, Joachim Amoako, Thomas Edmiston, Amila Sanjiva Ratnayake, Daphne Kabatoro, et al.
BMJ Global Health, 2026
Background The complexity of delivering trauma care makes the assessment of its provision challenging. The identification of bellwether procedures has previously been successful in the evaluation of global surgical care; however, any equivalent in assessing trauma care is currently lacking. Through a Delphi process, we aimed to produce the bellwether procedures and processes for global trauma care. Methods A global Delphi process was undertaken with healthcare professionals and academics involved in trauma care from across the world. A list of potential procedures and processes was identified through literature review and expert opinion, along with subsequent additional options suggested by respondents. Three successive rounds were completed, with respondents rating the importance of each procedure or process to be undertaken at any hospital that cares for trauma patients using a five-point Likert scale. Results A total of 411 respondents from 78 countries completed the initial round of the Delphi process, with minimal attrition observed across rounds. Following three successive rounds of the Delphi and functional aggregation, nine bellwethers of global trauma care were determined, subdivided into three functional categories: ‘Resuscitation & Stabilisation’—(1) Advanced Airway Management, (2) Short-term C-spine Immobilisation, (3) Long Bone Immobilisation; ‘Diagnosis & Monitoring’—(4) Blood Gas Analysis, (5) Focused Assessment with Sonography in Trauma (FAST) Scanning, (6) Continuous Access to CT Imaging; ‘Optimisation & Intervention’—(7) Blood Transfusion, (8) Tube Thoracostomy, (9) Laparotomy and Splenectomy. Conclusion The Global Trauma Care Delphi study has produced nine metrics that provide pragmatic indicators for the overall assessment of trauma care capabilities at any healthcare setting worldwide. These bellwethers of global trauma care can enable hospitals, local managers and health ministries to identify institutions or regions that may require more in-depth assessment, allowing standards in the management of traumatic injuries to improve.
Ventilation strategies in intensive care medicine
Carolin Jung, Peter Markus Spieth
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie AINS, 2026
A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial
Alexander Zarbock, Marlies Ostermann, Lui Forni, Christian Bode, Lennart Wild, et al.
Lancet, 2025
Radiomics-enhanced modelling approach for predicting the need for ECMO in ARDS patients: a retrospective cohort study
Martin Mirus, Eric Leitert, Rebecca Bockholt, Lars Heubner, Steffen Löck, et al.
Scientific Reports, 2025
Tidal volume and mortality during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a multicenter observational cohort study
Torben M. Rixecker, Jeannine L. Kühnle, Johannes Herrmann, Christopher Lotz, Christian Kühn, et al.
Annals of Intensive Care, 2025
Prehospital thrombolytic treatment of high-risk acute pulmonary embolism
Hugo Lanz, Leonhard Binzenhöfer, Tom Verbelen, Andrea Stadlbauer, Daniele Camboni, et al.
Critical Care, 2025
Patient perspectives on stress after ICU and a short primary care based psychological intervention – results from a qualitative sub‑study of the PICTURE trial
Antina Beutel, Linda Sanftenberg, Chris M. Friemel, Robert Philipp Kosilek, Maggie Schauer, et al.
BMC Primary Care, 2025
Association of intraoperative end-tidal CO2 levels with postoperative outcomes: a patient-level analysis of two randomised clinical trials
Prashant Nasa, David M.P. van Meenen, Frederique Paulus, Carlos Ferrando, Thomas Bluth, et al.
British Journal of Anaesthesia, 2025
Individual and combined effects of chemical and mechanical power on postoperative pulmonary complications: a secondary analysis of the REPEAT study
Lukas M. Müller‐Wirtz, Thijs A. Lilien, William M. Patterson, Sascha Ott, Roland C. E. Francis, et al.
Anaesthesia, 2025
Bleeding management in cases of direct oral anticoagulant therapy – Expert recommendations for emergency diagnostics and procedure
Anasthesiologie Und Intensivmedizin, 2025
Nucleated red blood cells as a prognostic marker for mortality in septic critically ill patients: An observational study
Felix Niebhagen, Anna Kirsch, Richard Schau, Sandra Waske, Lars Heubner, et al.
Anaesthesia Critical Care and Pain Medicine, 2025
Erratum to: Optimales neurologisches Outcome nach prolongierter Reanimation mit extrakorporaler Reanimation (eCPR) (Die Anaesthesiologie, (2024), 73, 6, (417-420), 10.1007/s00101-024-01419-z)
Andreas Fichtner, Susanne Hiller, Sven Schönfelder, Peter Spieth
Anaesthesiologie, 2025
Clinical Phenotyping in Acute Respiratory Distress Syndrome: Steps Towards Personalized Medicine
Paul Leon Petrick, Martin Mirus, Lars Heubner, Hani Harb, Mario Menk, et al.
Journal of Clinical Medicine, 2025
Impact of sarcopenia and obesity on mortality in older adults with SARS-CoV-2 infection: automated deep learning body composition analysis in the NAPKON-SUEP cohort
Sabine Schluessel, Benedikt Mueller, Olivia Tausendfreund, Michaela Rippl, Linda Deissler, et al.
Infection, 2025
Hemocompatible Coatings of Catheters Equipped with Electrochemical Sensors for Real-Time Monitoring of Critical Parameters in the Blood
Stephanie Klinghammer, Taufhik Hossain Tonmoy, Željko Janićijević, Manfred F. Maitz, Sascha Balakin, et al.
ACS Applied Polymer Materials, 2025
Association of preoperative smoking with the occurrence of postoperative pulmonary complications: A post hoc analysis of an observational study in 29 countries
Galina Dorland, W. Saadat, David M.P. van Meenen, Ary Serpa Neto, Michael Hiesmayr, et al.
Journal of Clinical Anesthesia, 2025
A year in review in Minerva Anestesiologica 2024: anesthesia, analgesia, and perioperative medicine
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Luca BRAZZI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2025
Management of high-risk acute pulmonary embolism: an emulated target trial analysis
Andrea Stadlbauer, Tom Verbelen, Leonhard Binzenhöfer, Tomaz Goslar, Alexander Supady, et al.
Intensive Care Medicine, 2025
Ventilation concepts under extracorporeal membrane oxygenation (ECMO) in acute respiratory distress syndrome (ARDS)
Thomas Bluth, Andreas Güldner, Peter M. Spieth
Zeitschrift Fur Pneumologie, 2025
Long-term characteristics and outcomes of septic critically ill patients with and without COVID-19
Felix Niebhagen, Lars Heubner, Anna Kirsch, Andreas Güldner, Hanns-Christoph Held, et al.
Journal of Critical Care, 2025
Associations of intraoperative end–tidal CO2 levels with postoperative outcome–secondary analysis of a worldwide observational study
Prashant Nasa, David M.P. van Meenen, Frederique Paulus, Marcelo Gama de Abreu, Sebastiaan M. Bossers, et al.
Journal of Clinical Anesthesia, 2025
Anticoagulation in venovenous extracorporeal membrane oxygenation
Carolin Jung, Thomas Stueber, Martin Mirus, Lars Heubner, Peter Markus Spieth
Frontiers in Medicine, 2025
Effects of pneumatic tube systems on viscoelastic coagulation tests in septic patients and healthy individuals: protocol of the randomized controlled VETaPT-trial
Martin Mirus, Erik Buehrer, Lars Heubner, Christian Schnabel, Thea Koch, et al.
Frontiers in Medicine, 2025
Effects of the primary lung infection on outcomes in patients with severe ARDS treated with ECMO: a retrospective analysis
Martin Mirus, Lars Heubner, Martin Brückner, Thomas Birkner, Andreas Güldner, et al.
Frontiers in Medicine, 2025
Impact of bleeding and thrombosis on outcome of 945 COVID-19 VV-ECMO cases from a German registry
Johannes Herrmann, Janno Schade, Patrick Meybohm, Noah Paschke, Martha E. Hübsch, et al.
Frontiers in Medicine, 2025
Effects of a general practitioner-led brief narrative exposure intervention on symptoms of post-traumatic stress disorder after intensive care (PICTURE): multicentre, observer blind, randomised controlled trial
Jochen Gensichen, Konrad F R Schmidt, Linda Sanftenberg, Robert P Kosilek, Chris M Friemel, et al.
BMJ, 2025
High Positive End-expiratory Pressure (PEEP) with Recruitment Maneuvers versus Low PEEP during General Anesthesia for Surgery: A Bayesian Individual Patient Data Meta-analysis of Three Randomized Clinical Trials
Guido Mazzinari, Fernando G. Zampieri, Lorenzo Ball, Niklas S. Campos, Thomas Bluth, et al.
Anesthesiology, 2025
Monitoring the efficiency of reversal on anti-Xa direct oral anticoagulants using point-of-care viscoelastic testing
Lars Heubner, Oliver Grottke, Oliver Vicent, Peter Markus Spieth, Jan Beyer-Westendorf
Thrombosis Journal, 2024
Serum neurofilament light chain as a sensitive biomarker for neuromonitoring during extracorporeal membrane oxygenation
Stefanie Fischer, Lars Heubner, Stephanie May, Puya Shalchi Amirkhiz, Jens Kuhle, et al.
Scientific Reports, 2024
Nucleated red blood cells as a prognostic marker for mortality in patients with SARS-CoV-2-induced ARDS: an observational study
Anna Kirsch, Felix Niebhagen, Miriam Goldammer, Sandra Waske, Lars Heubner, et al.
Journal of Anesthesia Analgesia and Critical Care, 2024
Sex dependence of postoperative pulmonary complications – A post hoc unmatched and matched analysis of LAS VEGAS
Tom D. Vermeulen, Liselotte Hol, Pien Swart, Michael Hiesmayr, Gary H. Mills, et al.
Journal of Clinical Anesthesia, 2024
Influence of anesthesia on surgical site infections
Teresa Herrmann, Peter Spieth, Torsten Richter
Gefasschirurgie, 2024
Influence of anesthesia on surgical site infections
Teresa Herrmann, Peter Spieth, Torsten Richter
Coloproctology, 2024
Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON)
Katharina S. Appel, Carolin Nürnberger, Thomas Bahmer, Christian Förster, Maria Cristina Polidori, et al.
Infection, 2024
Patient with symptoms of post-traumatic stress disorder after intensive care—a case report from the PICTURE study
Linda Sanftenberg, Julia Krevet, Robert Philipp Kosilek, Daniela Lindemann, Konrad Schmidt, et al.
Zeitschrift Fur Allgemeinmedizin, 2024
Prehospital ultrasound in emergency medicine
Oliver Vicent, Andreas W. Reske, Rosa Nickl, Rebecca Heinen, Peter M. Spieth
Anaesthesiologie, 2024
Prone positioning for acute respiratory distress syndrome in adults: Update on the physiological effects, indications and implementation
Sebastian Hafner, Philipp M. Lepper, Ralf M. Muellenbach, Hermann Wrigge, Onnen Moerer, et al.
Anaesthesiologie, 2024
Influence of anesthesia on surgical site infections
Teresa Herrmann, Peter Spieth, Torsten Richter
Anaesthesiologie, 2024
Optimal neurological outcome after prolonged resuscitation with extracorporal life support (eCPR)
Andreas Fichtner, Susanne Hiller, Sven Schönfelder, Peter Spieth
Anaesthesiologie, 2024
Statistical analysis plan for the biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2) study: An international randomised controlled multicentre trial
Thilo von Groote, Moritz Fabian Danzer, Melanie Meersch, Alexander Zarbock, Joachim Gerß, et al.
Critical Care and Resuscitation, 2024
Characteristics of co-infection and secondary infection amongst critically ill COVID-19 patients in the first two waves of the pandemic
Thomas De Corte, Katharina Kohler, Maurizio Cecconi, Jan J. De Waele, Andrew Conway Morris, et al.
Intensive Care Medicine, 2024
Extracorporeal cardiopulmonary resuscitation—An orientation
Axel Rand, Peter M. Spieth
Medizinische Klinik Intensivmedizin Und Notfallmedizin, 2024
Ventilation concepts under extracorporeal membrane oxygenation (ECMO) in acute respiratory distress syndrome (ARDS)
Thomas Bluth, Andreas Güldner, Peter M. Spieth
Anaesthesiologie, 2024
A year in review in Minerva Anestesiologica 2023: anesthesia, analgesia, and perioperative medicine
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Luca BRAZZI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2024
Transcriptional Levels of Intercellular Junction Proteins in an Alveolar Epithelial Cell Line Exposed to Irradiation or Bleomycin
E. S. Karetnikova, N. Jarzebska, R. N. Rodionov, P. M. Spieth, A. G. Markov
Bulletin of Experimental Biology and Medicine, 2024
Monitoring of Argatroban in Critically Ill Patients: A Prospective Study Comparing Activated Partial Thromboplastin Time, Point-of-Care Viscoelastic Testing with Ecarin Clotting Time and Diluted Thrombin Time to Mass Spectrometry
Lars Heubner, Reinhard Oertel, Oliver Tiebel, Nicole Mehlig-Warnecke, Jan Beyer-Westendorf, et al.
Anesthesiology, 2024
HEALTH-RELATED QUALITY OF LIFE AND PARTICIPATION AFTER INPATIENT REHABILITATION OF SEPSIS SURVIVORS WITH SEVERE SEQUELAE: A COHORT STUDY
Ulf Bodechtel, Thea Koch, Lars Heubner, Peter Spieth, Ines Rößler, et al.
Journal of Rehabilitation Medicine, 2024
A contemporary training concept in critical care cardiology
Leonhard Binzenhöfer, Nils Gade, Daniel Roden, Inas Saleh, Hugo Lanz, et al.
Frontiers in Cardiovascular Medicine, 2024
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase
Vinitha N. Ragavan, Pramod C. Nair, Natalia Jarzebska, Ramcharan Singh Angom, Luana Ruta, et al.
Nature Communications, 2023
Barriers and opportunities for implementation of a brief psychological intervention for post-ICU mental distress in the primary care setting – results from a qualitative sub-study of the PICTURE trial
Linda Sanftenberg, Antina Beutel, Chris Maria Friemel, Robert Philipp Kosilek, Maggie Schauer, et al.
BMC Primary Care, 2023
Extracorporeal cardiopulmonary resuscitation—An orientation
Axel Rand, Peter M. Spieth
Anaesthesiologie, 2023
Bleeding management in patients with direct oral anticoagulants
Lars HEUBNER, Oliver VICENT, Jan BEYER-WESTENDORF, Peter M. SPIETH
CMAJ Canadian Medical Association Journal, 2023
Hemostatic disorders associated with extracorporeal membrane oxygenation
Martin MIRUS, Lars HEUBNER, Johannes KALBHENN, Peter M. SPIETH
Minerva Anestesiologica, 2023
A year in review in Minerva Anestesiologica 2022: anesthesia, analgesia, and perioperative medicine
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Luca BRAZZI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2023
Organizing Pneumonia Treated with High-Dose Methylprednisolone in an Adolescent with COVID-19 Pneumonia Under Extracorporeal Membrane Oxygenation
Axel Rand, Sebastian Brenner, Peter Spieth
Lessons from the Icu, 2023
mRNA Levels of Epithelial and Mesenchymal Markers in Lung Epithelial Cell Lines
Ekaterina Sergeevna Karetnikova, Natalia Jarzebska, Roman Nikolaevich Rodionov, Elena Rubets, Alexander Georgievich Markov, et al.
Reports of Biochemistry and Molecular Biology, 2023
One-year follow-up of the CAPSID randomized trial for high-dose convalescent plasma in severe COVID-19 patients
Sixten Körper, Beate Grüner, Daniel Zickler, Thomas Wiesmann, Patrick Wuchter, et al.
Journal of Clinical Investigation, 2022
Predictive ability of viscoelastic testing using ClotPro® for short-term outcome in patients with severe Covid-19 ARDS with or without ECMO therapy: a retrospective study
Lars Heubner, Marvin Greiner, Oliver Vicent, Jan Beyer-Westendorf, Oliver Tiebel, et al.
Thrombosis Journal, 2022
Extreme obesity is a strong predictor for in-hospital mortality and the prevalence of long-COVID in severe COVID-19 patients with acute respiratory distress syndrome
Lars Heubner, Paul Leon Petrick, Andreas Güldner, Lea Bartels, Maximillian Ragaller, et al.
Scientific Reports, 2022
Circulating Dickkopf1 Parallels Metabolic Adaptations and Predicts Disease Trajectories in Patients With COVID-19
Nikolai P Jaschke, Alexander M Funk, Sophie Jonas, Romy M Riffel, Anupam Sinha, et al.
Journal of Clinical Endocrinology and Metabolism, 2022
Correction: Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set (Critical Care, (2022), 26, 1, (236), 10.1186/s13054-022-04108-8)
Andrew Conway Morris, Katharina Kohler, Thomas De Corte, Ari Ercole, Harm-Jan De Grooth, et al.
Critical Care, 2022
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Carolin E. M. Koll, Sina M. Pütz, Thierry Meurers, Chin Huang Lee, Mirjam Kohls, et al.
Scientific Data, 2022
Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set
Andrew Conway Morris, Katharina Kohler, Thomas De Corte, Ari Ercole, Harm-Jan De Grooth, et al.
Critical Care, 2022
Point-of-Care Assessment of Direct Oral Anticoagulation in Acute Ischemic Stroke: Protocol for a Prospective Observational Diagnostic Accuracy Study
Annahita Sedghi, Lars Heubner, Anna Klimova, Oliver Tiebel, Jörg Pietsch, et al.
Thrombosis and Haemostasis, 2022
Use of extracorporeal membrane oxygenation in non-elective major thoracic surgery for infectious lung abscess
Michael Schweigert, Attila Dubecz, Carlos F Giraldo Ospina, Peter Spieth, Ana Beatriz Almeida, et al.
European Journal of Cardio Thoracic Surgery, 2022
67/m—Fever and altered mentation on postoperative day 3 after PPPD: Preparation course anesthesiological intensive care medicine: case 4
L. Peters, P. Spieth
Anaesthesiologie, 2022
Changes in lung aeration and respiratory function after open abdominal surgery: A quantitative magnetic resonance imaging study
Lorenzo Ball, Simon Corrado Serafini, Anja Braune, Andreas Güldner, Thomas Bluth, et al.
Acta Anaesthesiologica Scandinavica, 2022
Enhancing Anticoagulation Monitoring and Therapy in Patients Undergoing Microvascular Reconstruction in Maxillofacial Surgery: A Prospective Observational Trial
Tom A. Schröder, Henry Leonhardt, Dominik Haim, Christian Bräuer, Kiriaki K. Papadopoulos, et al.
Journal of Personalized Medicine, 2022
Correction to: Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave: the global UNITE-COVID study (Intensive Care Medicine, (2022), 48, 6, (690-705), 10.1007/s00134-022-06705-1)
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, et al.
Intensive Care Medicine, 2022
Point of care coagulation management in anesthesiology and critical care
Lars HEUBNER, Martin MIRUS, Oliver VICENT, Andreas GÜLDNER, Oliver TIEBEL, et al.
Minerva Anestesiologica, 2022
Characteristics and outcomes of sepsis patients with and without COVID-19
Lars Heubner, Sara Hattenhauer, Andreas Güldner, Paul Leon Petrick, Martin Rößler, et al.
Journal of Infection and Public Health, 2022
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave: the global UNITE-COVID study
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, et al.
Intensive Care Medicine, 2022
Real-Time Monitoring of Blood Parameters in the Intensive Care Unit: State-of-the-Art and Perspectives
Rebecca Bockholt, Shaleen Paschke, Lars Heubner, Bergoi Ibarlucea, Alexander Laupp, et al.
Journal of Clinical Medicine, 2022
A year in review in Minerva Anestesiologica 2021 Anesthesia, analgesia, and perioperative medicine
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Luca BRAZZI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2022
Veno-venous extracorporeal membrane oxygenation (vv-ECMO) for severe respiratory failure in adult cancer patients: a retrospective multicenter analysis
Matthias Kochanek, Jan Kochanek, Boris Böll, Dennis A. Eichenauer, Gernot Beutel, et al.
Intensive Care Medicine, 2022
Decision support for the transfer of ICU patients
Medizintechnik Cologne, 2022
Classifying Ready-for-Transfer Patients in the Intensive Care Unit Based on Clinical Data
Franz Ehm, Volkmar Franz, Maic Regner, Udo Buscher, Hanns-Christoph Held, et al.
Lecture Notes in Operations Research, 2022
The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study
Guido Mazzinari, Ary Serpa Neto, Sabrine N. T. Hemmes, Goran Hedenstierna, Samir Jaber, et al.
BMC Anesthesiology, 2021
Influence of Anatomic Conditions on Efficacy and Safety of Combined Intermediate Cervical Plexus Block and Perivascular Infiltration of Internal Carotid Artery in Carotid Endarterectomy: A Prospective Observational Trial
Christopher Uhlig, Oliver Vicent, Stephanie Spieth, Stefan Ludwig, Christian Reeps, et al.
Ultrasound in Medicine and Biology, 2021
Energy requirements of long-term ventilated COVID-19 patients with resolved SARS-CoV-2 infection
Janusz von Renesse, Simone von Bonin, Hanns-Christoph Held, Ralph Schneider, Adrian M. Seifert, et al.
Clinical Nutrition Espen, 2021
Potential benefit of convalescent plasma transfusions in immunocompromised patients with COVID-19
Roman N Rodionov, Anne Biener, Peter Spieth, Martin Achleitner, Kristina Hölig, et al.
Lancet Microbe, 2021
Association of history of cerebrovascular disease with severity of COVID-19
Timo Siepmann, Annahita Sedghi, Jessica Barlinn, Katja de With, Lutz Mirow, et al.
Journal of Neurology, 2021
A year in review in Minerva Anestesiologica 2020 Anesthesia, analgesia, and perioperative medicine
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Edoardo CALDERINI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2021
Scarred Lung. An Update on Radiation-Induced Pulmonary Fibrosis
Natalia Jarzebska, Ekaterina S. Karetnikova, Alexander G. Markov, Michael Kasper, Roman N. Rodionov, et al.
Frontiers in Medicine, 2021
Increased risk of acute stroke among patients with severe COVID-19: a multicenter study and meta-analysis
T. Siepmann, A. Sedghi, E. Simon, S. Winzer, J. Barlinn, et al.
European Journal of Neurology, 2021
Results of the CAPSID randomized trial for high-dose convalescent plasma in patients with severe COVID-19
Sixten Körper, Manfred Weiss, Daniel Zickler, Thomas Wiesmann, Kai Zacharowski, et al.
Journal of Clinical Investigation, 2021
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: Post-hoc analysis of LAS VEGAS study
FERS for the LAS VEGAS investigators, Chiara Robba, the PROtective VEntilation Network and the Clinical Trial Network of the European Society of Anaesthesiology, Sabrine N. T. Hemmes, Ary Serpa Neto, et al.
BMC Anesthesiology, 2020
Molecular Dynamics of Lipopolysaccharide-Induced Lung Injury in Rodents
Hannes Domscheit, Maria A. Hegeman, Niedja Carvalho, Peter M. Spieth
Frontiers in Physiology, 2020
A year in review in Minerva Anestesiologica 2019. Anesthesia, analgesia, and perioperative medicine
Franco Cavaliere, Massimo Allegri, Alparslan Apan, Edoardo Calderini, Massimiliano Carassiti, et al.
Minerva Anestesiologica, 2020
Extracorporeal cardiopulmonary resuscitation: Tool or toy?
Christopher LOTZ, Ralf M. MUELLENBACH, Peter SPIETH
Minerva Anestesiologica, 2020
Effects of regional anesthesia techniques on local anesthetic plasma levels and complications in carotid surgery: A randomized controlled pilot trial
Thomas Rössel, Christopher Uhlig, Jörg Pietsch, Stefan Ludwig, Thea Koch, et al.
BMC Anesthesiology, 2019
ERS statement on chest imaging in acute respiratory failure
Davide Chiumello, Giuseppe Francesco Sferrazza Papa, Antonio Artigas, Belaid Bouhemad, Aleksandar Grgic, et al.
European Respiratory Journal, 2019
Mechanical ventilation strategies targeting different magnitudes of collapse and tidal recruitment in porcine acid aspiration-induced lung injury
Juliane Haase, Dorina C. Buchloh, Sören Hammermüller, Peter Salz, Julia Mrongowius, et al.
Journal of Clinical Medicine, 2019
52-year-old female with community-acquired pneumonia, acute respiratory distress syndrome: Preparation for the medical specialist examination: Part 25
A. Güldner, P. Spieth
Anaesthesist, 2019
Declining Mortality in Patients with Acute Respiratory Distress Syndrome: An Analysis of the Acute Respiratory Distress Syndrome Network Trials
Zhongheng Zhang, Peter Markus Spieth, Davide Chiumello, Hemant Goyal, ; Antoni Torres, et al.
Critical Care Medicine, 2019
Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications
A. Cortegiani, C. Gregoretti, A.S. Neto, S.N.T. Hemmes, L. Ball, et al.
British Journal of Anaesthesia, 2019
Ayear in review in minerva anestesiologica 2018
Franco Cavaliere, Massimo Allegri, Alparslan Apan, Edoardo Calderini, Massimiliano Carassiti, et al.
Minerva Anestesiologica, 2019
Blood transfusion associated lung injury
Maria Theresa Voelker, Peter Spieth
Journal of Thoracic Disease, 2019
Development of a compact stand-alone esophageal pressure measurement device
Andre J. Richter, Christian Schnabel, Peter Spieth, Emdund Koch
Current Directions in Biomedical Engineering, 2018
Magnetic resonance imaging for quantitative assessment of lung aeration: A pilot translational study
Lorenzo Ball, Anja Braune, Peter Spieth, Moritz Herzog, Karthikka Chandrapatham, et al.
Frontiers in Physiology, 2018
Storage injury and blood transfusions in trauma patients
Peter M. Spieth, Haibo Zhang
Current Opinion in Anaesthesiology, 2018
Variable versus conventional lung protective mechanical ventilation during open abdominal surgery (PROVAR): a randomised controlled trial
P.M. Spieth, A. Güldner, C. Uhlig, T. Bluth, T. Kiss, et al.
British Journal of Anaesthesia, 2018
Ayear in review in Minerva Anestesiologica 2017
Franco CAVALIERE, Massimo ALLEGRI, Alparslan APAN, Edoardo CALDERINI, Massimiliano CARASSITI, et al.
Minerva Anestesiologica, 2018
Beta blocker in septic shock
Christopher Uhlig, Peter Spieth
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie, 2018
Interhospital transfer of critically ill patients
Thomas Kiss, Alisa Bölke, Peter M. Spieth
Minerva Anestesiologica, 2017
Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications: LAS VEGAS - An observational study in 29 countries
European Journal of Anaesthesiology, 2017
Acute respiratory distress syndrome: Basic principles and treatment
P. M. Spieth, A. Güldner, M. Gama de Abreu
Anaesthesist, 2017
Will all ARDS patients be receiving mechanical ventilation in 2035? No
Matthieu Schmidt, Peter M. Spieth, Alberto Zanella
Intensive Care Medicine, 2017
A year in review in minerva anestesiologica 2016. Critical care. experimental and clinical studies
Franco Cavaliere, Guillermo M. Albaiceta, Gianni Biancofiore, Elena Bignami, Edoardo De Robertis, et al.
Minerva Anestesiologica, 2017
Regional tidal lung strain in mechanically ventilated normal lungs
Luis Felipe Paula, Tyler J. Wellman, Tilo Winkler, Peter M. Spieth, Andreas Güldner, et al.
Journal of Applied Physiology, 2016
Perioperative hemodynamic therapy: Goal-directed or meta-directed?
Minerva Anestesiologica, 2016
Randomized controlled trials – A matter of design
Timo Siepmann, Peter Markus Spieth, Anne Sophie Kubasch, Ana Isabel Penzlin, Ben Min-Woo Illigens, et al.
Neuropsychiatric Disease and Treatment, 2016
Personalized medicine for ARDS: the 2035 research agenda
Jeremy R. Beitler, Ewan C. Goligher, Matthieu Schmidt, Peter M. Spieth, Alberto Zanella, et al.
Intensive Care Medicine, 2016
Experimental blunt chest trauma - cardiorespiratory effects of different mechanical ventilation strategies with high positive end-expiratory pressure: A randomized controlled study
Dierk Schreiter, Nadja C. Carvalho, Sebastian Katscher, Ludger Mende, Alexander P. Reske, et al.
BMC Anesthesiology, 2016
In reply
David B. Auyong, Stanley C. Yuan, Alyse N. Rymer, Cynthia L. Green, Neil A. Hanson
Anesthesiology, 2016
In reply
Andreas Güldner, Thomas Kiss, Ary Serpa Neto, Sabrine N. T. Hemmes, Jaume Canet, et al.
Anesthesiology, 2015
Alpha-2 agonists: Back to the future of human anesthesia?
Minerva Anestesiologica, 2015
Non-ventilatory approaches to prevent postoperative pulmonary complications
Andreas Güldner, Peter M. Spieth, Marcelo Gama de Abreu
Best Practice and Research Clinical Anaesthesiology, 2015
Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: A comprehensive review of the role of tidal volume, positive end-expiratory pressure, and lung recruitment maneuvers
Andreas Güldner, Thomas Kiss, Ary Serpa Neto, Sabrine N. T. Hemmes, Jaume Canet, et al.
Anesthesiology, 2015
Anesthesia and monitoring in small laboratory mammals used in anesthesiology, respiratory and critical care research: A systematic review on the current reporting in top-10 impact factor ranked journals
Christopher Uhlig, Hannes Krause, Thea Koch, Marcelo Gama de Abreu, Peter Markus Spieth
Plos One, 2015
Correlation of lung collapse and gas exchange - A computer tomographic study in sheep and pigs with atelectasis in otherwise normal lungs
Samuel J. Wolf, Alexander P. Reske, Sören Hammermüller, Eduardo L. V. Costa, Peter M. Spieth, et al.
Plos One, 2015
Mechanical stress and the induction of lung fibrosis via the midkine signaling pathway
Rong Zhang, Ying Pan, Vito Fanelli, Sulong Wu, Alice Aili Luo, et al.
American Journal of Respiratory and Critical Care Medicine, 2015
Effects of ultraprotective ventilation, extracorporeal carbon dioxide removal, and spontaneous breathing on lung morphofunction and inflammation in experimental severe acute respiratory distress syndrome
Andreas Güldner, Thomas Kiss, Thomas Bluth, Christopher Uhlig, Anja Braune, et al.
Anesthesiology, 2015
A year in review in Minerva Anestesiologica 2014
Minerva Anestesiologica, 2015
Modulation of stress versus time product during mechanical ventilation influences inflammation as well as alveolar epithelial and endothelial response in rats
Peter M. Spieth, Pedro L. Silva, Cristiane S. N. B. Garcia, Debora S. Ornellas, Cynthia S. Samary, et al.
Anesthesiology, 2015
Positive end-expiratory pressure and variable ventilation in lung-healthy rats under general anesthesia
Luciana M. Camilo, Mariana B. Ávila, Luis Felipe S. Cruz, Gabriel C. M. Ribeiro, Peter M. Spieth, et al.
Plos One, 2014
Approaches to ventilation in intensive care
Peter Spieth, Thea Koch, Marcelo Gama de Abreu
Deutsches Arzteblatt International, 2014
To measure is to know - But know what you measure
Minerva Anestesiologica, 2014
Mechanotransduction in the lungs
Minerva Anestesiologica, 2014
Variable versus conventional lung protective mechanical ventilation during open abdominal surgery: Study protocol for a randomized controlled trial
Peter M Spieth, Andreas Güldner, Christopher Uhlig, Thomas Bluth, Thomas Kiss, et al.
Trials, 2014
The effects of salbutamol on epithelial ion channels depend on the etiology of acute respiratory distress syndrome but not the route of administration
Christopher Uhlig, Pedro L Silva, Débora Ornellas, Raquel S Santos, Paulo J Miranda, et al.
Respiratory Research, 2014
Pharmacological therapies for acute respiratory distress syndrome
Peter Markus Spieth, Haibo Zhang
Current Opinion in Critical Care, 2014
A new adaptive controller for volume-controlled mechanical ventilation in small animals
Robert Huhle, Peter M. Spieth, Andreas Güldner, Thea Koch, Marcelo Gama de Abreu
Experimental Lung Research, 2014
Mechanical ventilation-associated lung fibrosis in acute respiratory distress syndrome: A significant contributor to poor outcome
Nuria E. Cabrera-Benitez, John G. Laffey, Matteo Parotto, Peter M. Spieth, Jesús Villar, et al.
Anesthesiology, 2014
A year in review in Minerva Anestesiologica 2013
Minerva Anestesiologica, 2014
0896. Temporal changes in tidal recruitment compared to histologic outcome in experimental acute respiratory distress syndrome
Intensive Care Medicine Experimental, 2014
Higher levels of spontaneous breathing reduce lung injury in experimental moderate acute respiratory distress syndrome
Nadja C. Carvalho, Andreas Güldner, Alessandro Beda, Ines Rentzsch, Christopher Uhlig, et al.
Critical Care Medicine, 2014
Higher levels of spontaneous breathing induce lung recruitment and reduce global stress/strain in experimental lung injury
Andreas Güldner, Anja Braune, Nadja Carvalho, Alessandro Beda, Stefan Zeidler, et al.
Anesthesiology, 2014
Short-term effects of noisy pressure support ventilation in patients with acute hypoxemic respiratory failure
Peter M Spieth, Andreas Güldner, Robert Huhle, Alessandro Beda, Thomas Bluth, et al.
Critical Care, 2013
Rationale and study design of ViPS - variable pressure support for weaning from mechanical ventilation: Study protocol for an international multicenter randomized controlled open trial
Thomas Kiss, Andreas Güldner, Thomas Bluth, Christopher Uhlig, Peter Markus Spieth, et al.
Trials, 2013
Effects of intravascular volume replacement on lung and kidney function and damage in nonseptic experimental lung injury
Pedro L. Silva, Andreas Güldner, Christopher Uhlig, Nadja Carvalho, Alessandro Beda, et al.
Anesthesiology, 2013
Pulmonary embolism in mechanically ventilated patients: What the eye doesn't see, the heart can still grieve over
Peter M. Spieth, Marcelo Gama de Abreu
Critical Care Medicine, 2012
Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury
Spyridon Fortis, Peter M. Spieth, Wei-Yang Lu, Matteo Parotto, Jack J. Haitsma, et al.
Intensive Care Medicine, 2012
Comparative effects of proportional assist and variable pressure support ventilation on lung function and damage in experimental lung injury
Peter M. Spieth, Andreas Güldner, Alessandro Beda, Nadja Carvalho, Thomas Nowack, et al.
Critical Care Medicine, 2012
Variable pressure support-ventilation (Noisy PSV)
Journal Fur Anasthesie Und Intensivbehandlung, 2012
Lung recruitment in ARDS: We are still confused, but on a higher PEEP level
Peter M Spieth, Marcelo Gama de Abreu
Critical Care, 2012
Chronic obstructive pulmonary disease
Peter M. Spieth, Andreas Güldner, Marcelo Gama de Abreu
Current Opinion in Anaesthesiology, 2012
Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition
Nuria E. Cabrera-Benítez, Matteo Parotto, Martin Post, Bing Han, Peter M. Spieth, et al.
Critical Care Medicine, 2012
Adaptive control system for volume-controlled ventilation in small animals
Robert Huhle, Peter M. Spieth, Thea Koch, Marcelo Gama de Abreu
Biomedizinische Technik, 2012
Minimally invasive versus open oesophagectomy for oesophageal cancer
M Parotto, F Valenza, C Ori, PM Spieth
Lancet, 2012
Circadian rhythms: From basic mechanisms to the intensive care unit
Ming-Cheng Chan, Peter M. Spieth, Kieran Quinn, Matteo Parotto, Haibo Zhang, et al.
Critical Care Medicine, 2012
Extrapolation in the analysis of lung aeration by computed tomography: A validation study
Andreas W Reske, Anna Rau, Alexander P Reske, Manja Koziol, Beate Gottwald, et al.
Critical Care, 2011
Analyzing lung crackle sounds: Stethoscopes and beyond
P. M. Spieth, H. Zhang
Intensive Care Medicine, 2011
Forced oscillation technique: An alternative tool to define the optimal PEEP?
Vito Fanelli, Peter Spieth, Haibo Zhang
Intensive Care Medicine, 2011
Xenon and the developing brain
Minerva Anestesiologica, 2011
Distribution of regional lung aeration and perfusion during conventional and noisy pressure support ventilation in experimental lung injury
Alysson R. Carvalho, Peter M. Spieth, Andreas Güldner, Maximilano Cuevas, Nadja C. Carvalho, et al.
Journal of Applied Physiology, 2011
Computed tomographic assessment of lung weights in trauma patients with early posttraumatic lung dysfunction
Andreas W Reske, Alexander P Reske, Till Heine, Peter M Spieth, Anna Rau, et al.
Critical Care, 2011
Open lung approach vs acute respiratory distress syndrome network ventilation in experimental acute lung injury
P.M. Spieth, A. Güldner, A.R. Carvalho, M. Kasper, P. Pelosi, et al.
British Journal of Anaesthesia, 2011
Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support
Peter M. Spieth, Alysson R. Carvalho, Andreas Güldner, Michael Kasper, René Schubert, et al.
Critical Care Medicine, 2011
Effects of perfluorohexane vapor in the treatment of experimental lung injury
Jörg U. Bleyl, Axel R. Heller, Manuel Heintz, Matthias Schlemmer, Roland Koch, et al.
Pulmonary Pharmacology and Therapeutics, 2010
Regional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury
Marcelo Gama de Abreu, Maximiliano Cuevas, Peter M Spieth, Alysson R Carvalho, Volker Hietschold, et al.
Critical Care, 2010
Anesthesia in patients with chronic obstructive pulmonary diseases
P.M. Spieth, A. Güldner, M. Gama de Abreu
Anaesthesist, 2010
A novel adaptive control system for noisy pressure-controlled ventilation: A numerical simulation and bench test study
Alessandro Beda, Peter M. Spieth, Thomas Handzsuj, Paolo Pelosi, Nadja C. Carvalho, et al.
Intensive Care Medicine, 2010
Pretreatment with perfluorohexane vapor attenuates fMLP-induced lung injury in isolated perfused rabbit lungs
Jörg U. Bleyl, Axel R. Heller, Antonia Fehrenbach, Manuel Heintz, Heinz Fehrenbach, et al.
Experimental Lung Research, 2010
Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury
Peter M. Spieth, Alysson R. Carvalho, Paolo Pelosi, Catharina Hoehn, Christoph Meissner, et al.
American Journal of Respiratory and Critical Care Medicine, 2009
Anaesthesiological management of one-lung anaesthesia
Anasthesiologie Und Intensivmedizin, 2009
Effects of different levels of pressure support variability in experimental lung injury
Peter M. Spieth, Alysson R. Carvalho, Andreas Güldner, Paolo Pelosi, Oleg Kirichuk, et al.
Anesthesiology, 2009
Comparison of objective methods to classify the pattern of respiratory sinus arrhythmia during mechanical ventilation and paced spontaneous breathing
N C Carvalho, A Beda, M G de Abreu, P M Spieth, P Granja-Filho, et al.
Physiological Measurement, 2009
An adaptive controller for noisy pressure controlled ventilation
Alessandro Beda, Peter M. Spieth, Thomas Handzsuj, Paolo Pelosi, Nadja C. Carvalho, et al.
Ifmbe Proceedings, 2009
Pressure support ventilation and biphasic positive airway pressure improve oxygenation by redistribution of pulmonary blood flow
Alysson R. Carvalho, Peter M. Spieth, Paolo Pelosi, Alessandro Beda, Agnaldo J. Lopes, et al.
Anesthesia and Analgesia, 2009
Automatic lung segmentation of helical-CT scans in experimental induced lung injury
L. M. Cuevas, P. M. Spieth, A. R. Carvalho, M. G. de Abreu, E. Koch
Ifmbe Proceedings, 2008
Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration
Alysson R. Carvalho, Peter M. Spieth, Paolo Pelosi, Marcos F. Vidal Melo, Thea Koch, et al.
Intensive Care Medicine, 2008
New trends in ventilation - Noisy ventilation?
Journal Fur Anasthesie Und Intensivbehandlung, 2008
Noisy pressure support ventilation: A pilot study on a new assisted ventilation mode in experimental lung injury
Marcelo Gama de Abreu, Peter M. Spieth, Paolo Pelosi, Alysson R. Carvalho, Christiane Walter, et al.
Critical Care Medicine, 2008
Variable mechanical ventilation: Breaking the monotony
M. Gama de Abreu, P. M. Spieth, P. Pelosi
Yearbook of Intensive Care and Emergency Medicine 2009, 2007
Erratum: Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury (Intensive Care Medicine (2006) DOI: 10.1007/s00134-006-0428-7)
Peter M. Spieth, Lilla Knels, Michael Kasper, André Domingues Quelhas, Bärbel Wiedemann, et al.
Intensive Care Medicine, 2007
Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury
Peter M. Spieth, Lilla Knels, Michael Kasper, André Domingues Quelhas, Bärbel Wiedemann, et al.
Intensive Care Medicine, 2007
Comparative effects of vaporized perfluorohexane and partial liquid ventilation in oleic acid-induced lung injury
Marcelo Gama de Abreu, André Domingues Quelhas, Peter Spieth, Götz Bräuer, Lilla Knels, et al.
Anesthesiology, 2006

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