SUNDARAMAHALINGAM M A
@nitt.edu
Research Scholar, Department of Chemical Engineering
National Institute of Technology Tiruchirappalli
RESEARCH INTERESTS
Bioenergy
21
Scopus Publications
339
Scholar Citations
9
Scholar h-index
8
Scholar i10-index
Scopus Publications
- Synergistic biodiesel production from food flavourant industry wastewater using Rhodotorula mucilaginosa and Chlorella vulgaris
M.A. Sundaramahalingam and P. Sivashanmugam
Elsevier BV - Production of lipase from Priestia endophytica SSP strain and its potential application in deinking of printed paper
M. A. Sundaramahalingam, Pavithra Vijayachandran, J. Rajeshbanu, and P. Sivashanmugam
Springer Science and Business Media LLC - Optimization of process parameters in acoustic cavitation mediated extraction of pectin from Prosopis juliflora pod peel and its analytical characterization
Ponmanian M, Vishnuprasad S, Suriiyakumar R, Gokulakrishnan S A, Ganeshmoorthy I, and Sundaramahalingam M A
Springer Science and Business Media LLC - An Algorithmic Soft Computing Technique for Identifying Lipase-Producing Yeast Using Its Gene Expression Data
Sundaramahalingam M A, Relli Teja, and Sivashanmugam P
CRC Press - Surfactant Combined Ultrasonic Pre-treatment for the disintegration of Sargassum tennerimum (marine macroalgae) and Evaluation of its Efficiency for the Generation of Biohydrogen
A.V. Snehya, M.A. Sundaramahalingam, J. Rajesh Banu, and P. Sivashanmugam
Springer Science and Business Media LLC - Production of microbial carotenoid using innate inherent of the food industry wastewater
M.A. Sundaramahalingam and P. Sivashanmugam
Elsevier BV - Biodiesel production from a novel renewable source through the ultrasound-assisted transesterification process, using energy efficient nanocatalyst developed from waste material
M.A. Sundaramahalingam and P. Sivashanmugam
Elsevier BV - Concomitant strategy of wastewater treatment and biodiesel production using innate yeast cell (Rhodotorula mucilaginosa) from food industry sewerage and its energy system analysis
M.A. Sundaramahalingam and P. Sivashanmugam
Elsevier BV - Surfactant-assisted ultrasonic fragmentation of mixed fruit and vegetable biomass: Its impact on biomethane yield and energy analysis
M. Shanthi, M.A. Sundaramahalingam, J. Rajeshbanu, and P.Sivashanmugam
Elsevier BV - Biohydrogen recovery by biosurfactant-induced ultrasonic fractionation of macroalgae, Sargassum tennerimum
M. A. Sundaramahalingam, A. V. Snehya, P. Sivashanmugam, J. Rajeshbanu, and S. Anandan
Springer Science and Business Media LLC - In silico approach for enhancing innate lipid content of Yarrowia lipolytica, by blocking the acyl-CoA oxidase-1 enzyme, using various analogous compounds of lipids
M.A. Sundaramahalingam, C. Amrutha, J. Rajeshbanu, K. Thirukumaran, S. Manibalan, Muthupandian Ashokkumar, and P. Sivashanmugam
Informa UK Limited
Abstract Yarrowia lipolytica is used as a model in this study to screen the potential candidates for inflating the innate lipid content of the cell. This study focuses on reducing the lipid degradation that occurs by the β-oxidation process and discursively increasing the innate lipid content. Acyl-CoA oxidase-1, the primary and initial enzyme involved in the lipid degradation pathway, was selected as a target and blocked using various lipid analogous compounds. The blocking study was carried out using molecular docking and dynamic studies using computation tools. The largest active site pocket located around the Phe-394 amino acid of the target protein is taken as a site for docking. The molecular docking was performed for the selected compounds (citric acid, Finsolv, lactic acid, oxalic acid, Tween-80 and Triton X-100) and the docking results were compared with the outcome of the standard molecule (octadecatrienoic acid). Citric acid, Finsolv, Tween-80 and Triton X-100 were found to be the potential candidates for blocking the target molecule in the static condition using docking studies, revealing a minimum binding energy requirement than the standard molecule. They were further taken for a dynamics study using GROMACS software. The RMSD, RMSF, number of hydrogen bond interactions and radius of gyration of the complex molecules were studied in a dynamic approach for 100 ns. Citric acid has been found to be the potential hit compound to block acyl-CoA oxidase-1 enzyme with its maximum hydrogen interaction and minimum fluctuations. It also revealed out the minimum total energy requirement for the complex formation. Graphical Abstract HIGHLIGHTS Suggesting a discursive strategy for inflating innate lipid content in Yarrowia lipolytica Molecular docking dynamics study of acyl-CoA oxidase-1 of Y. lipolytica with lipid analogous compounds. Molecular dynamics study of lipid analogous with acyl-CoA oxidase-1 of Y. lipolytica In silico strategy for bioenergy compounds Communicated by Ramaswamy H. Sarma - Studies on evaluation of pretreatment efficiency of surfactant mediated ultrasonic pretreatment of Sargassum tennerimum (marine macroalgae) for achieving profitable biohydrogen production
A.V. Snehya, M.A. Sundaramahalingam, J. Rajeshbanu, and P. Sivashanmugam
Elsevier BV - A review on contemporary approaches in enhancing the innate lipid content of yeast cell
M.A. Sundaramahalingam, P. Sivashanmugam, J. Rajeshbanu, and Muthupandian Ashokkumar
Elsevier BV - Construction of Feedforward Multilayer Perceptron Model for Diagnosing Leishmaniasis Using Transcriptome Datasets and Cognitive Computing
M. A. Sundaramahalingam, Ritika Kabra, and Shailza Singh
Springer Nature Singapore - Studies on evaluation of surfactant coupled sonication pretreatment on Ulva fasciata (marine macroalgae) for enhanced biohydrogen production
A.V. Snehya, M.A. Sundaramahalingam, J. Rajeshbanu, S. Anandan, and P. Sivashanmugam
Elsevier BV - An encapsulated report on enzyme-assisted transesterification with an allusion to lipase
M. A. Sundaramahalingam, C. Amrutha, P. Sivashanmugam, and J. Rajeshbanu
Springer Science and Business Media LLC - Insights about sustainable biodiesel production from microalgae biomass: A review
Michael Rahul S, Sundaramahalingam MA, Shivamthi CS, Shyam Kumar R, Varalakshmi P, Karthikumar S, Kanimozhi J, Vinoth Kumar R, Sabarathinam S, Ganesh Moorthy I,et al.
Hindawi Limited
Production of biodiesel from microalgae can be categorized as a symbiotic engineering solution focusing on energy and environmental problems. This review presents a collection of recent methods adopted for the production of biodiesel from microalgae. Microalgae are tiny cell factories which yield a large quantity of biomass by employing different methods of cultivation and using different types of harvesting techniques. Different strategies like nutrient starvation and micronutrient supplementation for hyper lipid accumulation to produce biodiesel for competing with the high market demand for fossil fuel are discussed. The use of different cultivation techniques for increasing the algal biomass in the recent scenario is focused. Also, improvement in the design strategies of bioreactors like the open pond, photobioreactors, and hybrid systems is included in the review. Further, diverse technologies for lipid improvement, including manipulating the bioprocess parameters and genetic engineering, are addressed. Also, microalgae for biorefinery approaches solve pollution problems, and its biomass can be used for biodiesel production which is elaborated in detail. The possibility of production of biodiesel from microalgae at a larger scale by overcoming the main bottlenecks in different steps of algal growth like high biomass cultivation, investment factor, and implementation of biorefinery approaches to address the current energy demand is also proposed. - An intensified approach for transesterification of biodiesel from Annona squamosa seed oil using ultrasound-assisted homogeneous catalysis reaction and its process optimization
M.A. Sundaramahalingam, S. Karthikumar, R. Shyam Kumar, Karl J. Samuel, S. Shajahan, V. Sivasubramanian, P. Sivashanmugam, P. Varalakshmi, Asad Syed, Najat Marraiki,et al.
Elsevier BV - Progress in natural polymer engineered biomaterials for transdermal drug delivery systems
V.S. Sivasankarapillai, S.S. Das, F. Sabir, M.A. Sundaramahalingam, J.C. Colmenares, S. Prasannakumar, M. Rajan, A. Rahdar, and G.Z. Kyzas
Elsevier BV - Fungal clan for assisting the treatment of industrial outpour as myco-antidotes
- Bioreduction based synthesis of silver nanocoats and their application in development of nano embedded medical fabrics
RECENT SCHOLAR PUBLICATIONS
- Biohydrogen recovery by biosurfactant-induced ultrasonic fractionation of macroalgae, Sargassum tennerimum
MA Sundaramahalingam, AV Snehya, P Sivashanmugam, J Rajeshbanu, ...
Biomass Conversion and Biorefinery 15 (1), 1083-1091 2025 - Synergistic biodiesel production from food flavourant industry wastewater using Rhodotorula mucilaginosa and Chlorella vulgaris
MA Sundaramahalingam, P Sivashanmugam
Process Safety and Environmental Protection 191, 2064-2073 2024 - Optimization of process parameters in acoustic cavitation mediated extraction of pectin from Prosopis juliflora pod peel and its analytical characterization
M Ponmanian, S Vishnuprasad, R Suriiyakumar, SA Gokulakrishnan, ...
Biomass Conversion and Biorefinery, 1-12 2024 - Production of lipase from Priestia endophytica SSP strain and its potential application in deinking of printed paper
MA Sundaramahalingam, P Vijayachandran, J Rajeshbanu, ...
Biomass Conversion and Biorefinery 14 (13), 13861-13875 2024 - Surfactant Combined Ultrasonic Pre-treatment for the disintegration of Sargassum tennerimum (marine macroalgae) and Evaluation of its Efficiency for the
AV Snehya, MA Sundaramahalingam, JR Banu, P Sivashanmugam
BioEnergy Research 16 (4), 2529-2538 2023 - Production of microbial carotenoid using innate inherent of the food industry wastewater
MA Sundaramahalingam, P Sivashanmugam
Journal of Molecular Liquids 388, 122772 2023 - Concomitant strategy of wastewater treatment and biodiesel production using innate yeast cell (Rhodotorula mucilaginosa) from food industry sewerage and its energy system analysis
MA Sundaramahalingam, P Sivashanmugam
Renewable Energy 208, 52-62 2023 - Biodiesel production from a novel renewable source through the ultrasound-assisted transesterification process, using energy efficient nanocatalyst developed from waste material
PS M.A. Sundaramahalingam
Fuel 346, 128397 2023 - Surfactant-assisted ultrasonic fragmentation of mixed fruit and vegetable biomass: Its impact on biomethane yield and energy analysis
M Shanthi, MA Sundaramahalingam, J Rajeshbanu, P Sivashanmugam
Fuel 334, 126617 2023 - Studies on evaluation of pretreatment efficiency of surfactant mediated ultrasonic pretreatment of Sargassum tennerimum (marine macroalgae) for achieving profitable biohydrogen
AV Snehya, MA Sundaramahalingam, J Rajeshbanu, P Sivashanmugam
International Journal of Hydrogen Energy 47 (39), 17184-17193 2022 - A review on contemporary approaches in enhancing the innate lipid content of yeast cell
MA Sundaramahalingam, P Sivashanmugam, J Rajeshbanu, ...
Chemosphere 293, 133616 2022 - Construction of Feedforward Multilayer Perceptron Model for Diagnosing Leishmaniasis Using Transcriptome Datasets and Cognitive Computing
RKSS Sundaramahalingam M A
Machine Learning and Systems Biology in Genomics and Health, 1-15 2022 - Studies on evaluation of surfactant coupled sonication pretreatment on Ulva fasciata (marine macroalgae) for enhanced biohydrogen production
AV Snehya, MA Sundaramahalingam, J Rajeshbanu, S Anandan, ...
Ultrasonics Sonochemistry 81 (https://doi.org/10.1016/j.ultsonch.2021.), 105853 2021 - An intensified approach for transesterification of biodiesel from Annona squamosa seed oil using ultrasound-assisted homogeneous catalysis reaction and its process optimization
IGM M.A. Sundaramahalingam, S. Karthikumar, R. Shyam Kumar, Karl J. Samuel ...
Fuel 291 2021 - In silico approach for enhancing innate lipid content of Yarrowia lipolytica, by blocking the acylCoA oxidase-1 enzyme, using various analogous compounds of lipids
MAPS M.A. Sundaramahalingam, C. Amrutha, J. Rajeshbanu, K. Thirukumaran, S ...
Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080 2021 - An encapsulated report on enzyme‑assisted transesterification with an allusion to lipase
MASCAPSJ Rajeshbanu
3 Biotech 11 (481), https://doi.org/10.1007/s13205-021-03003 2021 - FUNGAL CLAN FOR ASSISTING THE TREATMENT OF INDUSTRIAL OUTPOUR AS MYCO-ANTIDOTES
MASP Sivashanmugam
Microbes for a Sustainable Environment and Human Welfare: Advancements and 2021 - Progress in natural polymer engineered biomaterials for transdermal drug delivery systems
VS Sivasankarapillai, SS Das, F Sabir, MA Sundaramahalingam, ...
Materials Today Chemistry 19, 100382 2020 - Insights about sustainable biodiesel production from microalgae biomass: A review
M Rahul S, S MA, S CS, GM I
International Journal of Energy Research 2020 - INVITRO STUDIES ON PHYTOCHEMICALS ANALYSIS AND LARVICIDAL EFFICACY OF MEDICINAL PLANT EXTRACTS AGAINST CULEX QUINQUEFASCIATUS
MSKENK S.Narendhiran, L. Saravanan, M.A.Sundaramahalingam, J.Banu Priya, P.V ...
AMERICAN JOURNAL OF BIOLOGICAL AND PHARMACEUTICAL RESEARCH 1 (3), 145-150 2014
MOST CITED SCHOLAR PUBLICATIONS
- Progress in natural polymer engineered biomaterials for transdermal drug delivery systems
VS Sivasankarapillai, SS Das, F Sabir, MA Sundaramahalingam, ...
Materials Today Chemistry 19, 100382 2020
Citations: 101 - An intensified approach for transesterification of biodiesel from Annona squamosa seed oil using ultrasound-assisted homogeneous catalysis reaction and its process optimization
IGM M.A. Sundaramahalingam, S. Karthikumar, R. Shyam Kumar, Karl J. Samuel ...
Fuel 291 2021
Citations: 60 - Insights about sustainable biodiesel production from microalgae biomass: A review
M Rahul S, S MA, S CS, GM I
International Journal of Energy Research 2020
Citations: 38 - Studies on evaluation of surfactant coupled sonication pretreatment on Ulva fasciata (marine macroalgae) for enhanced biohydrogen production
AV Snehya, MA Sundaramahalingam, J Rajeshbanu, S Anandan, ...
Ultrasonics Sonochemistry 81 (https://doi.org/10.1016/j.ultsonch.2021.), 105853 2021
Citations: 32 - A review on contemporary approaches in enhancing the innate lipid content of yeast cell
MA Sundaramahalingam, P Sivashanmugam, J Rajeshbanu, ...
Chemosphere 293, 133616 2022
Citations: 24 - Biodiesel production from a novel renewable source through the ultrasound-assisted transesterification process, using energy efficient nanocatalyst developed from waste material
PS M.A. Sundaramahalingam
Fuel 346, 128397 2023
Citations: 16 - Studies on evaluation of pretreatment efficiency of surfactant mediated ultrasonic pretreatment of Sargassum tennerimum (marine macroalgae) for achieving profitable biohydrogen
AV Snehya, MA Sundaramahalingam, J Rajeshbanu, P Sivashanmugam
International Journal of Hydrogen Energy 47 (39), 17184-17193 2022
Citations: 14 - Concomitant strategy of wastewater treatment and biodiesel production using innate yeast cell (Rhodotorula mucilaginosa) from food industry sewerage and its energy system analysis
MA Sundaramahalingam, P Sivashanmugam
Renewable Energy 208, 52-62 2023
Citations: 10 - Production of lipase from Priestia endophytica SSP strain and its potential application in deinking of printed paper
MA Sundaramahalingam, P Vijayachandran, J Rajeshbanu, ...
Biomass Conversion and Biorefinery 14 (13), 13861-13875 2024
Citations: 9 - An encapsulated report on enzyme‑assisted transesterification with an allusion to lipase
MASCAPSJ Rajeshbanu
3 Biotech 11 (481), https://doi.org/10.1007/s13205-021-03003 2021
Citations: 9 - COMPARATIVE ANALYSIS OF PHYTOCHEMICALS, ANTIBIOGRAM OF SELECTED PLANTS IN SOLANACEAE FAMILY AND ITS CHARACTERIZATION STUDIES
SMMA AKILAN.C.A, SRIVIDHYA.M, MOHANA PRIYA.C, JEBA SAMUEL.C.S
International Journal of Pharmacy and Pharmaceutical Sciences 6 (2), 946-950 2014
Citations: 8 - Production of microbial carotenoid using innate inherent of the food industry wastewater
MA Sundaramahalingam, P Sivashanmugam
Journal of Molecular Liquids 388, 122772 2023
Citations: 3 - Surfactant-assisted ultrasonic fragmentation of mixed fruit and vegetable biomass: Its impact on biomethane yield and energy analysis
M Shanthi, MA Sundaramahalingam, J Rajeshbanu, P Sivashanmugam
Fuel 334, 126617 2023
Citations: 3 - Bioreduction Based Synthesis of Silver Nanocoats and their Application in Development of Nano Embedded Medical Fabrics
M Srividhya, C Mohanapriya, CA Akilan, K Kathirvelan, AP Subitha, ...
International journal of pharmaceutical sciences review and research 27 (2 2014
Citations: 3 - Synergistic biodiesel production from food flavourant industry wastewater using Rhodotorula mucilaginosa and Chlorella vulgaris
MA Sundaramahalingam, P Sivashanmugam
Process Safety and Environmental Protection 191, 2064-2073 2024
Citations: 2 - Surfactant Combined Ultrasonic Pre-treatment for the disintegration of Sargassum tennerimum (marine macroalgae) and Evaluation of its Efficiency for the
AV Snehya, MA Sundaramahalingam, JR Banu, P Sivashanmugam
BioEnergy Research 16 (4), 2529-2538 2023
Citations: 2 - In silico approach for enhancing innate lipid content of Yarrowia lipolytica, by blocking the acylCoA oxidase-1 enzyme, using various analogous compounds of lipids
MAPS M.A. Sundaramahalingam, C. Amrutha, J. Rajeshbanu, K. Thirukumaran, S ...
Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080 2021
Citations: 2 - Optimization of process parameters in acoustic cavitation mediated extraction of pectin from Prosopis juliflora pod peel and its analytical characterization
M Ponmanian, S Vishnuprasad, R Suriiyakumar, SA Gokulakrishnan, ...
Biomass Conversion and Biorefinery, 1-12 2024
Citations: 1 - Construction of Feedforward Multilayer Perceptron Model for Diagnosing Leishmaniasis Using Transcriptome Datasets and Cognitive Computing
RKSS Sundaramahalingam M A
Machine Learning and Systems Biology in Genomics and Health, 1-15 2022
Citations: 1 - FUNGAL CLAN FOR ASSISTING THE TREATMENT OF INDUSTRIAL OUTPOUR AS MYCO-ANTIDOTES
MASP Sivashanmugam
Microbes for a Sustainable Environment and Human Welfare: Advancements and 2021
Citations: 1