Presently Dr Harish Kr. Shakya is working in Manipal University Jaipur as Associate Professor in the Artificial Intelligence & Machine Learning Department from September 2023. Dr Shakya has Completed his Ph.D. in Computer science & Engineering Department from the Indian Institute of Technology (BHU) Varanasi in 2018.His research interests includes social network analysis, soft computing techniques & Evolutinory algorithms. He has around 10 years of teaching and research experience. He holds bachelor’s degree in information technology from RJIT BSF Academy Gwalior and Completed his M.E. in Computer Engineering from SGSITS Indore (M.P.) India. Dr Shakya is a member/Fellow of various repudiated professional organizations i.e. FIETE, IEI, IEEE, ACM, IAENG, ICSES, CSTA, SAISE, IACSIT, and many more.
EDUCATION
Ph.D. (Computer Science & Engineering) IIT BHU Varanasi
ME (Computer Engineering) SGSITS Indore
BE (Information Technology) RJIT BSF ACADEMY Gwalior
Bioinformatics-Driven Identification of Ferroptosis-Related Gene Signatures Distinguishing Active and Latent Tuberculosis Rakesh Arya, Hemlata Shakya, Viplov Kumar Biswas, Gyanendra Kumar, Sumendra Yogarayan, et al. Genes, 2025 Background: Tuberculosis (TB) remains a major global public health challenge, and diagnosing it can be difficult due to issues such as distinguishing active TB from latent TB infection (LTBI), as well as the sample collection process, which is often time-consuming and lacks sensitivity and specificity. Ferroptosis is emerging as an important factor in TB pathogenesis; however, its underlying molecular mechanisms are not fully understood. Thus, there is a critical need to establish ferroptosis-related diagnostic biomarkers for tuberculosis (TB). Methods: This study aimed to identify and validate potential ferroptosis-related genes in TB infection while enhancing clinical diagnostic accuracy through bioinformatics-driven gene identification. The microarray expression profile dataset GSE28623 from the Gene Expression Omnibus (GEO) database was used to identify ferroptosis-related differentially expressed genes (FR-DEGs) associated with TB. Subsequently, these genes were used for immune cell infiltration, Gene Set Enrichment Analysis (GSEA), functional enrichment and correlation analyses. Hub genes were identified using Weighted Gene Co-expression Network Analysis (WGCNA) and validated in independent datasets GSE37250, GSE39940, GSE19437, and GSE31348. Results: A total of 21 FR-DEGs were identified. Among them, four hub genes (ACSL1, PARP9, TLR4, and ATG3) were identified as diagnostic biomarkers. These biomarkers were enriched in immune-response related pathways and were validated. Immune cell infiltration, GSEA, functional enrichment and correlation analyses revealed that multiple immune cell types could be activated by FR-DEGs. Throughout anti-TB therapy, the expression of the four hub gene signatures significantly decreased in patients cured of TB. Conclusions: In conclusion, ferroptosis plays a key role in TB pathogenesis. These four hub gene signatures are linked with TB treatment effectiveness and show promise as biomarkers for differentiating TB from LTBI.
E-Voting System over Conventional Voting System Using Blockchain Technology Vishan Kumar Gupta, Neeraj Jain, Harish Shakya, Shaili Gupta, Paras Jain, et al. Proceedings of the International Conference on Electrical Electronics and Computer Science with Advance Power Technologies A Future Trends Ice2cpt 2025, 2025
Optimizing cervical cancer diagnosis with a hybrid deep neural network and progressive resizing on pap smear WSIs NK Chauhan, A Kumar, A Jain, K Singh, D Kumar, SS Singh, HK Shakya Scientific Reports , 2026 2026
A hybrid multi-stream deep learning model for cognitive feature-based schizophrenia detection M Arumugam, M Nandagopal, HK Shakya Discover Computing 29 (1), 254 , 2026 2026
Detection of benign prostatic hyperplasia using RGB prostate images and deep learning R Srivastava, R Kumar, S Kant, HK Shakya Scientific Reports , 2026 2026
PPWCS: A Strategy for Enhancing Caching Performance in Content-Centric Networking Enabled Consumer IoT Systems S Kumar, R Tiwari, SS Singh, H Shakya, G Kumar, AK Bashir IEEE Transactions on Consumer Electronics , 2026 2026
Low-light driver drowsiness detection for real-time safety assistance using dual attention mechanisms in deep learning model S Saxena, Angel, M Khurana, S Tiwari, HK Shakya Scientific Reports , 2026 2026
Deep Learning Approaches for Real-Time Intrusion Detection and Threat Classification in Cybersecurity Systems AS Reddy, A Samatha, N Joshi, N Chauhan, A Jain, HK Shakya 2026 International Conference on Multidisciplinary Innovations For Smart … , 2026 2026
Explainable AI Framework for Climate Risk Prediction and Environmental Decision Support GS Atwal, A Singla, Y Lohumi, M Kumari, D uma Vishweshwar, ... 2026 International Conference on Multidisciplinary Innovations For Smart … , 2026 2026
Large Language Models in the Diagnosis of Squamous Cell Carcinoma: The State of the Art, Problems, and Future Perspectives J Meena, VK Gupta, H Shakya, P Jain, H Tiwari, K Kokila 2026 IEEE Madhya Pradesh Section Conference (MPCON), 471-476 , 2026 2026
Human-Like Hiring at Scale: A Conversational AI and Computer Vision Approach A Aggarwal, S Sachar, H Singh, VK Gupta, H Shakya 2026 IEEE Madhya Pradesh Section Conference (MPCON), 933-938 , 2026 2026
Leveraging similarity and community-based features for link prediction in temporal social networks using attention-enabled LSTM: R. Ahuja et al. R Ahuja, S Kaur, HK Shakya, SS Singh Scientific Reports , 2025 2025
Hybrid Convolution-Recurrent Deep Learning Framework for High-Precision Lung and Colon Disease Detection A Singh, S Kumar, J Gangrade, S Gangrade, HK Shakya SN Computer Science 6 (8), 998 , 2025 2025
Smart Agriculture: Harnessing Machine Learning for Plant Disease Detection SA Wagle, N Chankhore, R Iyer, G Shukla, S Sridhar, HK Shakya 2025 IEEE 7th International Conference on Computing, Communication and … , 2025 2025
Facial Expression Recognition and Deep Learning: Revolutionizing Personalized Music Therapy SA Wagle, O Mishra, R Iyer, G Shukla, S Sridhar, HK Shakya 2025 IEEE 7th International Conference on Computing, Communication and … , 2025 2025
Plant disease detection using a hybrid dilated CNN with attention mechanisms and optimized mask RCNN segmentation K Sahu, S Tiwari, MK Singh, J Pahareeya, HK Shakya, G Kumar, ... Scientific Reports , 2025 2025 Citations: 4
E-Voting System Over Conventional Voting System Using Blockchain Technology VK Gupta, N Jain, H Shakya, S Gupta, P Jain, K Bhatt 2025 International Conference on Electrical, Electronics, and Computer … , 2025 2025
Wavelet-Pix2pix Framework for CT Denoising and Super Resolution C Vishwakarma, S Jha, G Bansal, HK Shakya, DK Jha International Conference on Artificial Intelligence and Computing, 283-295 , 2025 2025
Bioinformatics-driven identification of ferroptosis-related gene signatures distinguishing active and latent tuberculosis R Arya, H Shakya, VK Biswas, G Kumar, S Yogarayan, HK Shakya, JJ Kim Genes 16 (6), 716 , 2025 2025 Citations: 2
Big data meets social networks: A survey of analytical strategies and research challenges SS Singh, S Singh, K Singh, V Srivastava, HK Shakya IEEE Access , 2025 2025 Citations: 9
Cache Invalidation-Based Optimization in Next Generation Wireless Network: Taxonomy, Review, and Future Directions R Tiwari, S Kumar, SS Singh, HK Shakya IEEE Access , 2025 2025
MRI-to-CT Scan Conversion Using CycleGAN: A Deep Learning Approach S Jha, C Vishwakarma, V Ananya, HK Shakya 2025 IEEE International Conference on Computer, Electronics, Electrical … , 2025 2025
MOST CITED SCHOLAR PUBLICATIONS
Social network analysis: A survey on process, tools, and application SS Singh, S Muhuri, S Mishra, D Srivastava, HK Shakya, N Kumar ACM computing surveys 56 (8), 1-39 , 2024 2024 Citations: 136
Energy-Proficient cluster enrichment in wireless sensor networks via categorized fuzzy clustering and Multi-Hop routing optimization HK Shakya, AK Chandanan, C Subbalakshmi, G Khambra, MS Ansari, ... SN Computer Science 6 (1), 25 , 2024 2024 Citations: 64
Clustering of people in social network based on textual similarity K Singh, HK Shakya, B Biswas Perspectives in Science 8, 570-573 , 2016 2016 Citations: 63
Advanced security solutions for conversational AI R Sikarwar, HK Shakya, A Kumar, A Rawat Conversational Artificial Intelligence, 287-301 , 2024 2024 Citations: 55
A survey on information diffusion models in social networks SS Singh, K Singh, A Kumar, HK Shakya, B Biswas International conference on advanced informatics for computing research, 426-439 , 2018 2018 Citations: 54
Mining of high‐utility itemsets with negative utility K Singh, HK Shakya, A Singh, B Biswas Expert Systems 35 (6), e12296 , 2018 2018 Citations: 41
EHNL: An efficient algorithm for mining high utility itemsets with negative utility value and length constraints K Singh, A Kumar, SS Singh, HK Shakya, B Biswas Information Sciences 484, 44-70 , 2019 2019 Citations: 32
Hybrid recommendation system for movies using artificial neural network S Sharma, HK Shakya Expert Systems with Applications 258, 125194 , 2024 2024 Citations: 20
Nested sentiment analysis for ESG impact: Leveraging FinBERT to predict market dynamics based on eco-friendly and non-eco-friendly product perceptions with explainable AI A Saxena, A Santhanavijayan, HK Shakya, G Kumar, B Balusamy, ... Mathematics 12 (21), 3332 , 2024 2024 Citations: 19
Mitigation strategies for distributed denial of service (DDoS) in SDN: A survey and taxonomy S Karnani, HK Shakya Information Security Journal: A Global Perspective 32 (6), 444-468 , 2023 2023 Citations: 19
A location based novel recommender framework of user interest through data categorization VM Saurabh Sharma, Harish Kumar Shakya Materials Today: Proceedings 47 (special issue), 7155-7161 , 2021 2021 Citations: 13
Big data meets social networks: A survey of analytical strategies and research challenges SS Singh, S Singh, K Singh, V Srivastava, HK Shakya IEEE Access , 2025 2025 Citations: 9
A review on social network analysis methods and algorithms R Sikarwar, HK Shakya, SS Singh 2021 13th International Conference on Computational Intelligence and … , 2021 2021 Citations: 9
An efficient genetic algorithm for fuzzy community detection in social network HK Shakya, K Singh, B Biswas Advanced Informatics for Computing Research: First International Conference … , 2017 2017 Citations: 9
Advanced Privacy Preserving Model for Smart Healthcare Using Deep Learning P Jain, HK Shakya, A Lala 2023 6th International Conference on Contemporary Computing and Informatics … , 2023 2023 Citations: 7
Recommendation system for movies using improved version of som with hybrid filtering methods S Sharma, H Shakya International Conference on Machine Intelligence and Smart Systems, 181-197 , 2023 2023 Citations: 7
Hybrid real-time implicit feedback SOM-based movie recommendation systems S Sharma, HK Shakya International Conference on Computing, Communications, and Cyber-Security … , 2022 2022 Citations: 7
Happiness index in social network K Singh, HK Shakya, B Biswas Advanced Informatics for Computing Research: First International Conference … , 2017 2017 Citations: 7
An efficient approach to discovering frequent patterns from data cube using aggregation and directed graph K Singh, HK Shakya, B Biswas Proceedings of the Sixth International Conference on Computer and … , 2015 2015 Citations: 7
SOM and Hybrid Filtering: Pioneering Next-Gen Movie Recommendations in the Entertainment Industry. S Sharma, GP Dubey, HK Shakya, A Sharma Fusion: Practice & Applications 16 (2) , 2024 2024 Citations: 6