Biotechnology, Waste Management and Disposal, Agricultural and Biological Sciences, Renewable Energy, Sustainability and the Environment
26
Scopus Publications
507
Scholar Citations
10
Scholar h-index
10
Scholar i10-index
Scopus Publications
In silico STUDIES OF THE HEPATITIS B VIRAL PROTEIN FOR DRUG DISCOVERY Oxidation Communications, 2023
NANOTHERANOSTICS FOR CANCER THERAPY AND DETECTION: STRATEGIES, PROMISES AND IMPEDIMENTS Oxidation Communications, 2023
CHITOSAN NANOPARTICLE ENCAPSULATED WITH Terminalia chebula – in vitro ANTIDIABETIC ACTIVITY Oxidation Communications, 2023
Collagen – Zinc Oxide Nanoparticles (ZnO NPs) Composites for Wound Healing – A Review Thiruchelvi. R, Priyadharshini. S, Mugunthan. P, Rajakumari K. Research Journal of Pharmacy and Technology, 2022 Fish Collagen which is also called as Marine collagen has gained immense attention in the recent years as an appropriate alternative to mammalian collagen. Fish collagen is essentially the superhero of collagen sourced from animals. Fish collagen is made up of mostly Type 1 collagen, which makes up to 70 percent of total skin. Collagen is found to heal wounds by attracting new skin cells to the wound site. It promotes healing and provide platform for new tissue growth. Zinc Oxide Nanoparticles are nanoparticles of ZnO that have diameter less than 100 nanometres. Recently, ZnO Nanoparticles have shown to disrupt bacterial cell membrane integrity, reduce cell surface hydrophobicity and enhancement of intracellular bacterial killing. The ZnO nanoparticles were synthesized from the plant. The paper will describe the potency of fish skin waste, problems in healing burn injuries, collagen extraction, green synthesis of ZnO NPs, collagen and ZnO NPs applications in wound dressing. Since ZnO nanoparticles have much anti-bacterial activity it can be combined with collagen and characterized for the application in wound healing management.
Screening for Anti-Diabetic Peptides from Moringa oleifera leaves Thiruchelvi. R, Priyadharshini. S, Rajakumari K. Research Journal of Pharmacy and Technology, 2021 Moringa oleifera commonly called as Drumstick tree is a multipurpose tree and it is widely present in the places like India, Asia, Africa, etc. Its leaves are emetic and their juices are used for medicinal purposes. Diabetes mellitus is a clinical syndrome with insufficient insulin secretion and abnormal glucose tolerance. It is a group of diseases which results in too much sugar in the blood. Leaves from Moringa oleifera were collected, analysed for their anti- diabetic activity. First the proteins are extracted using protein extraction methods, estimated using Lowry’s method, and then anti- diabetic activity was checked using Glucose uptake assay by yeast cells, where the plant extract (small proteins) was able to uptake glucose. SDS-PAGE was carried out to check the protein’s size and molecular weight. The characterization of Moringa oleifera conducted in this study shows that the small peptides from the leaves of this plant can contribute significantly in the daily recommended intake of it, since it serves as a rich source of all minerals, vitamins etc. This study has confirmed that the small peptides from the leaves of M.oleifera can fight against diabetics and the result indicated that Murungai (Moringa) leaves are suitable source of green leaf to reduce the diabetic complications in diabetic patients.
The antiviral and antibacterial properties of plectranthus amboinicus and piper longum with the addition to focaccia bread nutritional value and sensory evaluation H.M. Moyeenudin, Thiruchelvi R. Research Journal of Pharmacy and Technology, 2021 Focaccia is an Italian bread baked with herbs in a similar way to pizza, this can be utilized as a regular meal in daily basis, thus the bread prepared without cheese, it is considered as a good health supplement. The addition of herbs like Plectranthus amboinicus (Indian Borage) and Piper longum (long Pepper) to focaccia may increase the medicinal value. Borage is used as a medicine in treating contagious diseases like viral flu and cough through antiviral, antibacterial and antifebrile activity, likewise Piper longum acts as an antibacterial and have immunomodulation properties, piper longum is commonly known as Indian long pepper mostly used in siddha medicine to treat cough and respiratory disease. The upper respiratory infection mainly influence cough, sinusitis, sore throat, pharyngitis, also develop lung inflammation and this herb could be consumed in regular diet. The objective of this research is to analyze antiviral and antibacterial properties of Plectranthus amboinicus and Piper longum. Furthermore, to evaluate the Focaccia bread in addition with these herbs in preparation by sensory evaluation.
Statistical optimization of textile dye effluent adsorption by Gracilaria edulis using Plackett-Burman design and response surface methodology R. Venkataraghavan, R. Thiruchelvi, D. Sharmila Heliyon, 2020 Statistical optimization models were employed to optimize the adsorption of textile dye effluent onto Gracilaria edulis. Significant factors responsible for adsorption were determined using Plackett-Burman design (PBD) and were time, pH, and dye concentration. Box-Behnken (BB) design was used for further optimization. The predicted and the experimental values were found to be in good agreement, the coefficient of determination value 0.9935 and adjusted coefficient of determination value 0.9818 indicated that the model was significant. The results of predicted response optimization showed that maximum decolorization could be attained with time 131.51 min, pH 7.48, and dye concentration 23.13%. The model was validated experimentally with 92.65% decolorization efficiency. The experiment was confirmed using Fourier transform infrared spectroscopy (FTIR), high-resolution scanning electron microscope coupled with energy dispersive X-ray analysis (HR-SEM-EDX), X-ray diffraction spectrometry (XRD) and Brunauer-Emmett-Teller (BET) surface area and pore size analysis techniques. Desorption studies at various pH (2–14) were performed and a maximum of 23% of the dye was recovered from the adsorbed biomass.
Nanobots in today’s world R. Thiruchelvi, Eesani Sikdar, Aryaman Das, K. Rajakumari Research Journal of Pharmacy and Technology, 2020 Nanobots are the recent and may be the future technology for many fields. The health care industry of today is focusing on developing minimally invasive techniques for diagnosis, as well as treatment of ailments. They are microscopic in nature and are used for various research purpose. It is used for medical as well an industrial purpose. some nanobots are used as a microscopic in surgical fields. This kind of microscopes is used to arrange the atoms. it is used in MRI where light is passed precisely through the concern region to heat it at 131⁰F which destroys the concern cells. In industrial purpose precisely it is used in oil industries. It is used in nanoparticles to produce light more efficiently. They are used in the manufacture of small processors and chips and in computers circuits.it helps to bridge the technological gaps between physics, chemistry and biology in nanoscale.
Raisin R. Thiruchelvi, P. Jayashree, Gulzar Ahmad Nayik, Amir Gull, Tehmeena Ahad, et al. Antioxidants in Vegetables and Nuts Properties and Health Benefits, 2020
Screening of process parameters influencing the biosorption of textile effluents using plackett-Burman design Indian Journal of Environmental Protection, 2019
Protective effect of crude sulphated polysaccharide from Turbinaria ornata on isoniazid rifampicin induced hepatotoxicity and oxidative stress in the liver, kidney and brain of adult Swiss albino rats Indian Journal of Biochemistry and Biophysics, 2018
In-vivo anti-hyperglycemic effect of herbal extracts Tribulus terrestris (L) and Curcuma amada (R) on streptozotocin-induced diabetic rats and its associated histopathological … NMA Kumaravel Kaliaperumal a, Bilal Ahmad Bhat b, Kumaran Subramanian c ... Heliyon 10 (10.1016/j.heliyon.2024.e24009), 10 (2024) e24009 , 2024 2024 Citations: 20
Fat and Alzheimer’s Disease S Rodriguez, R Thiruchelvi, A Justin Thenmozhi, DS Cosio, ... Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach, 67-89 , 2023 2023
In silico STUDIES OF THE HEPATITIS B VIRAL PROTEIN FOR DRUG DISCOVERY KR S. PANDIYAN ARUN, R. THIRUCHELVI* Oxidation Communications 2, 272-282 , 2023 2023 Citations: 1
NANOTHERANOSTICS FOR CANCER THERAPY AND DETECTION: STRATEGIES, PROMISES AND IMPEDIMENTS KR VARSHA JACQULYN, S. LAKSHMI PRIYA, R. THIRUCHELVI* Oxidation Communications 1, 16-36 , 2023 2023
CHITOSAN NANOPARTICLE ENCAPSULATED WITH Terminalia chebula-in vitro ANTIDIABETIC ACTIVITY. R NATH, K Rajakumari, R Thiruchelvi, S Romauld, P Vivek Oxidation Communications 46 (1) , 2023 2023 Citations: 5
Individual and Synergistic Potential of Bioactive Compounds from Chrysopogon Zizanioides Against Main-Protease of SARS-Cov-2 using Computational Approach V Ragunathan, T Ramakrishnan, R Narayanan Biosciences Biotechnology Research Asia 19 (3), 657-670 , 2022 2022
Collagen–zinc oxide nanoparticles (ZnO NPs) composites for wound healing–A review R Thiruchelvi, S Priyadharshini, P Mugunthan, K Rajakumari Research Journal of Pharmacy and Technology 15 (6), 2838-2844 , 2022 2022 Citations: 6
Potential of bio hydrogen production from dark fermentation of sewage waste water–a review R Thiruchelvi, NK Kumari, KN Rajnish Biosciences Biotechnology Research Asia 19 (2), 347 , 2022 2022 Citations: 9
Internet of Medical Things (IoMT)–Medical Applications and It's Cyber Security V Jacqulyn, R Thiruchelvi, K Rajakumari Applications of Artificial Intelligence and Machine Learning in Healthcare , 2022 2022 Citations: 1
The phytochemical components of caesalpinia sappan in treating respiratory ailments through an herbal soup in addition with sensory evaluation HM Moyeenudin, R Thiruchelvi, AW Lawrence, RJ Williams Materials Today: Proceedings 56, 2167-2171 , 2022 2022 Citations: 5
Screening for anti-diabetic peptides from Moringa oleifera leaves R Thiruchelvi, S Priyadharshini, MK Rajakumari Research Journal of Pharmacy and Technology 14 (11), 5886-5890 , 2021 2021 Citations: 3
The antiviral and antibacterial properties of Plectranthus Amboinicus and Piper Longum with the addition to focaccia bread nutritional value and sensory evaluation HM Moyeenudin, R Thiruchelvi Research Journal of Pharmacy and Technology 14 (9), 4951-4956 , 2021 2021 Citations: 5
Isolation and characterization of glucanase producing bacteria from forest tree litter PR Dwarakanath, K Rajakumari, R Thiruchelvi Research Journal of Pharmacy and Technology 14 (2), 916-920 , 2021 2021 Citations: 3
Optimization of environmental parameters by Plackett-Burman design and response surface methodology for the adsorption of Malachite green onto Gracilaria edulis R Thiruchelvi, R Venkataraghavan, D Sharmila Materials Today: Proceedings 37, 1859-1864 , 2021 2021 Citations: 25
Synthesis of silver nanoparticle using marine red seaweed Gelidiella acerosa-a complete study on its biological activity and its characterisation R Thiruchelvi, P Jayashree, K Mirunaalini Materials Today: Proceedings 37, 1693-1698 , 2021 2021 Citations: 32
Diabetic retinopathy its genetics and single nucleotide polymorphism associated with multi-ethnic cohort–a review R Thiruchelvi, K Raghunathan Materials Today: Proceedings 37, 1640-1647 , 2021 2021 Citations: 5
Bioplastics as better alternative to petro plastic R Thiruchelvi, A Das, E Sikdar Materials Today: Proceedings 37, 1634-1639 , 2021 2021 Citations: 112
In-Silico analysis to identify the potent inhibitor of Rho GTPase activating protein for the usage of the Glaucoma R Thiruchelvi, C Shivanika Materials Today: Proceedings 37, 1897-1904 , 2021 2021 Citations: 3
Raisin R Thiruchelvi, P Jayashree, GA Nayik, A Gull, T Ahad, M Thakur, TR Shah, ... Antioxidants in Vegetables and Nuts-Properties and Health Benefits, 523-537 , 2020 2020 Citations: 3
Statistical optimization of textile dye effluent adsorption by Gracilaria edulis using Plackett-Burman design and response surface methodology R Venkataraghavan, R Thiruchelvi, D Sharmila Heliyon 6 (10) , 2020 2020 Citations: 91
MOST CITED SCHOLAR PUBLICATIONS
Bioplastics as better alternative to petro plastic R Thiruchelvi, A Das, E Sikdar Materials Today: Proceedings 37, 1634-1639 , 2021 2021 Citations: 112
Statistical optimization of textile dye effluent adsorption by Gracilaria edulis using Plackett-Burman design and response surface methodology R Venkataraghavan, R Thiruchelvi, D Sharmila Heliyon 6 (10) , 2020 2020 Citations: 91
Gas Chromatography-mass spectrometry Analysis of Methanol Extracts from Marine Red Seaweed Gracilaria corticata. V Ragunathan, J Pandurangan, T Ramakrishnan Pharmacognosy Journal 11 (3) , 2019 2019 Citations: 44
A review on DNA nanobots: A new techniques for cancer treatment U Devasena, P Brindha, R Thiruchelvi Asian J Pharm Clin Res 11 (6), 61-4 , 2018 2018 Citations: 44
Synthesis of silver nanoparticle using marine red seaweed Gelidiella acerosa-a complete study on its biological activity and its characterisation R Thiruchelvi, P Jayashree, K Mirunaalini Materials Today: Proceedings 37, 1693-1698 , 2021 2021 Citations: 32
Optimization of environmental parameters by Plackett-Burman design and response surface methodology for the adsorption of Malachite green onto Gracilaria edulis R Thiruchelvi, R Venkataraghavan, D Sharmila Materials Today: Proceedings 37, 1859-1864 , 2021 2021 Citations: 25
In-vivo anti-hyperglycemic effect of herbal extracts Tribulus terrestris (L) and Curcuma amada (R) on streptozotocin-induced diabetic rats and its associated histopathological … NMA Kumaravel Kaliaperumal a, Bilal Ahmad Bhat b, Kumaran Subramanian c ... Heliyon 10 (10.1016/j.heliyon.2024.e24009), 10 (2024) e24009 , 2024 2024 Citations: 20
Antioxidant, antibacterial, and anticancer activity from marine red algae Gracilaria edulis TS Hemasudha, R Thiruchelvi, P Balashanmugam Asian J Pharm Clin Res 12 (2), 276-279 , 2019 2019 Citations: 18
Protective effect of crude sulphated polysaccharide from turbinaria ornata on isoniazid rifampicin induced hepatotoxicity and oxidative stress in the liver, kidney and brain of … MSG Mohan, T Ramakrishnan, V Mani, A Achary Indian J Biochem Biophys 55, 237 , 2018 2018 Citations: 17
Protective effects of Terminalia chebula fruit extract against cadmium-induced nephrotoxicity in rats R Thiruchelvi, D Arul, S Meenakshi, K Subramanian Int J Environ Biol 2 (3), 108-112 , 2012 2012 Citations: 15
Potential of bio hydrogen production from dark fermentation of sewage waste water–a review R Thiruchelvi, NK Kumari, KN Rajnish Biosciences Biotechnology Research Asia 19 (2), 347 , 2022 2022 Citations: 9
EVALUATION OF ANTIBACTERIAL, ANTIOXIDANT, AND ANTICANCER POTENTIALS FROM MARINE RED ALGAE GRACILARIA CORTICATA BP JAYASREE P1, THIRUCHELVI R1* Asian Journal of Pharmaceutical and clinical research 11 (7), 1-4 , 2018 2018 Citations: 8
New biotechnological routes for greener bio-plastics from seaweeds R Thiruchelvi, K Kavitha, K Shankari Research Journal of Pharmacy and Technology 13 (5), 2488-2492 , 2020 2020 Citations: 7
Preliminary Phytochemical Analysis of the Crude extract of Marine Red and Brown Seaweeds BP Thiruchelvi. R Jayashree. P., Hemashree. T, Hemasudha T. S. Research J. Pharm. and Tech 11 (10), 4407-4410. , 2018 2018 Citations: 7
Collagen–zinc oxide nanoparticles (ZnO NPs) composites for wound healing–A review R Thiruchelvi, S Priyadharshini, P Mugunthan, K Rajakumari Research Journal of Pharmacy and Technology 15 (6), 2838-2844 , 2022 2022 Citations: 6
Nanobots in Today's World R Thiruchelvi, E Sikdar, A Das, K Rajakumari Research Journal of Pharmacy and Technology 13 (4), 2031-2037 , 2020 2020 Citations: 6
Synthesis of nano particles using algae and its application in dye degradation – A review DURT R1* International Journal of Research and Analytical Reviews 6 (1), pg. 252-256 , 2019 2019 Citations: 6
CHITOSAN NANOPARTICLE ENCAPSULATED WITH Terminalia chebula-in vitro ANTIDIABETIC ACTIVITY. R NATH, K Rajakumari, R Thiruchelvi, S Romauld, P Vivek Oxidation Communications 46 (1) , 2023 2023 Citations: 5
The phytochemical components of caesalpinia sappan in treating respiratory ailments through an herbal soup in addition with sensory evaluation HM Moyeenudin, R Thiruchelvi, AW Lawrence, RJ Williams Materials Today: Proceedings 56, 2167-2171 , 2022 2022 Citations: 5
The antiviral and antibacterial properties of Plectranthus Amboinicus and Piper Longum with the addition to focaccia bread nutritional value and sensory evaluation HM Moyeenudin, R Thiruchelvi Research Journal of Pharmacy and Technology 14 (9), 4951-4956 , 2021 2021 Citations: 5
GRANT DETAILS
• MSME- Ministry of Micro, Small & Medium Enterprises (M/o MSME)- Co-investigator in MSME entitled “Sustainable Use of Fruit and Vegetable waste to Enhance Food Packaging Performance”- Research grant lakhs
• New Product Development scheme (VISTAS)- Extraction of Nano Cellulose from Cissus quadrangularis and its hydrogel incorporation with bandage for wound healing- Received-25,000INR
RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)
Thiruchelvi.R, Jayashree.P, Abishek Biswal, Development of Bio-Nano composite degradable Plastic (2019) (201941045088)
Rajakumari.K, Sanjana.M, Thiruchelvi.R, Sustainable Biocement production using microbial Consortium (2022) (202241039057)
CONSULTANCY
• Co-Principal Investigator for the Consultancy project on Extraction and Characterization Studies on Marine Red Algae at Avanz Bio Pvt. Ltd.
• Screening optimization and analysis of selected natural product lead molecules and its anticancer studies at Armatz Biotech Training and Research Institute
Industry, Institute, or Organisation Collaboration
Aman Aqua Bio Chemical free plant Activator Manufacturer.
INDUSTRY EXPERIENCE
• Played a key role in Technology development, manufacturing, and sales, by
• Managing weekly activities of small-scale factory & Market research and product promotion.
• Formulated successful simple chemical free sustainable farming method.
• Promotion, Training, and consultation (Disease Control) and Biofertilizers carrier Formulation.
• New product development for Farmer Interested Groups
STARTUP
SIGA BIOTECH- Converting Waste Biomass into useful Products by using Biotechnological skills
SOCIAL, ECONOMIC, or ACADEMIC BENEFITS
Qualified as District Head of Tiruvallur in All India Startup & Entrepreneur Association (AISEA) (April 2022)
Awarded with Global contour award by ACE International Pte Ltd., Singapore on May 2021.
Awarded with Toycathon 2021 cell on Exceptional contribution as Primary Evaluator under Ministry of Education innovation Cell (Government of India) December 2021.
Awarded with Top 20 Most Promising Women Educators in Tamil Nadu by Academic Council Of uLektz on March 2019.
Awarded Best Presentation under PSG Nano challenge 2018(Innovation and Product Development) with Cash prize 10,000 & Certificate December 2018.
