Vasileios Andrianopoulos
Verified @outlook.com
College Lecturer & Curriculum Writer / Clinical Exercise Physiologist - Researcher.
EDUCATION
Physical Education & Sport Science (BSc), Exercise and Health (MSc), Field exercise testing in COPD (PhD).
RESEARCH INTERESTS
Exercise Physiology, exercise in chronic disease, exercise testing, Pulmonary Rehabilitation, Cognitive Impairment, COPD.
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Dimitrios I. Bourdas, Panteleimon Bakirtzoglou, Antonios K. Travlos, Vasileios Andrianopoulos, and Emmanouil Zacharakis
MDPI AG
This dataset aimed to explore associations between pre-SARS-CoV-2 infection exercise and sports-related physical activity (PA) levels and disease severity, along with treatments administered following the most recent SARS-CoV-2 infection. A comprehensive analysis investigated the relationships between PA categories (“Inactive”, “Low PA”, “Moderate PA”, “High PA”), disease severity (“Sporadic”, “Episodic”, “Recurrent”, “Frequent”, “Persistent”), and treatments post-SARS-CoV-2 infection (“No treatment”, “Home remedies”, “Prescribed medication”, “Hospital admission”, “Intensive care unit admission”) within a sample population (n = 5829) from the Hellenic territory. Utilizing the Active-Q questionnaire, data were collected from February to March 2023, capturing PA habits, participant characteristics, medical history, vaccination status, and illness experiences. Findings revealed an independent relationship between preinfection PA levels and disease severity (χ2 = 9.097, df = 12, p = 0.695). Additionally, a statistical dependency emerged between PA levels and illness treatment categories (χ2 = 39.362, df = 12, p < 0.001), particularly linking inactive PA with home remedies treatment. These results highlight the potential influence of preinfection PA on disease severity and treatment choices following SARS-CoV-2 infection. The dataset offers valuable insights into the interplay between PA, disease outcomes, and treatment decisions, aiding future research in shaping targeted interventions and public health strategies related to COVID-19 management.
Dimitrios I. Bourdas, Panteleimon Bakirtzoglou, Antonios K. Travlos, Vasileios Andrianopoulos, and Emmanouil Zacharakis
Elsevier BV
Dimitrios I. Bourdas, Panteleimon Bakirtzoglou, Antonios K. Travlos, Vasileios Andrianopoulos, and Emmanouil Zacharakis
MDPI AG
This study investigated changes in physical activity (PA) after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection while considering age, PA level, underlying medical conditions (UMCs), vaccination profiles/types, re-infections, disease severity, and treatment. Data were collected from 5829 respondents by using a validated web-based questionnaire. The findings showed that there was a significant overall decrease in PA (−16.2%), including in daily occupation (−11.9%), transportation (−13.5%), leisure-time (−16.4%), and sporting (−27.6%) activities. Age, PA level, UMCs, vaccination profiles/types, disease severity, and treatment played a role in determining PA in individuals’ post-acute SARS-CoV-2 infections. Re-infections did not impact the decline in PA. Unvaccinated individuals experienced a significant decline in PA (−13.7%). Younger (−22.4%) and older adults (−22.5%), those with higher PA levels (−20.6%), those with 2–5 UMCs (−23.1%), those who were vaccinated (−16.9%) or partially vaccinated (−19.1%), those with mRNA-type vaccines only (−17.1%), those with recurrent (−19.4%)-to-persistent (−54.2%) symptoms, and those that required hospital (−51.8%) or intensive care unit (−67.0%) admission during their infections had more pronounced declines in PA. These findings emphasize the complex relationship between post-acute SARS-CoV-2 infection and PA and highlight the need for targeted interventions, further research, and multidisciplinary care to promote PA resumption and mitigate long-term effects on global public health.
Olivier Van Hove, Vasileios Andrianopoulos, Ali Dabach, Olivier Debeir, Alain Van Muylem, Dimitri Leduc, Alexandre Legrand, Rudy Ercek, Véronique Feipel, and Bruno Bonnechère
Wiley
INTRODUCTION
Over the last 5 years, the analysis of respiratory patterns presents a growing usage in clinical and research purposes, but there is still currently a lack of easy-to-use and affordable devices to perform such kind of evaluation.
OBJECTIVES
The aim of this study is to validate a new specifically developed method, based on Kinect sensor, to assess respiratory patterns against spirometry under various conditions.
METHODS
One hundred and one participants took parts in one of the three validations studies. Twenty-five chronic respiratory disease patients (14 with chronic obstructive pulmonary disease (COPD) [65 ± 10 years old, FEV1 = 37 (15% predicted value), VC = 62 (20% predicted value)], and 11 with lung fibrosis (LF) [64 ± 14 years old, FEV1 = 55 (19% predicted value), VC = 62 (20% predicted value)]) and 76 healthy controls (HC) were recruited. The correlations between the signal of the Kinect (depth and respiratory rate) and the spirometer (tidal volume and respiratory rate) were computed in part 1. We then included 66 HC to test the ability of the system to detect modifications of respiratory patterns induced by various conditions known to modify respiratory pattern (cognitive load, inspiratory load and combination) in parts 2 and 3.
RESULTS
There is a strong correlation between the depth recorded by the Kinect and the tidal volume recorded by the spirometer: r = 0.973 for COPD patients, r = 0.989 for LF patients and r = 0.984 for HC. The Kinect is able to detect changes in breathing patterns induced by different respiratory disturbance conditions, gender and oral task.
CONCLUSIONS
Measurements performed with the Kinect sensors are highly correlated with the spirometer in HC and patients with COPD and LF. Kinect is also able to assess respiratory patterns under various loads and disturbances. This method is affordable, easy to use, fully automated and could be used in the current clinical context. Respiratory patterns are important to assess in daily clinics. However, there is currently no affordable and easy-to-use tool to evaluate these parameters in clinics. We validated a new system to assess respiratory patterns using the Kinect sensor in patients with chronic respiratory diseases.
Vasileios Andrianopoulos, Rainer Gloeckl, Tessa Schneeberger, Inga Jarosch, Ioannis Vogiatzis, Emily Hume, Rembert A. Koczulla, and Klaus Kenn
Elsevier BV
Olivier Van Hove, Ana Maria Cebolla, Vasileios Andrianopoulos, Dimitri Leduc, Pierre Antoine Guidat, Véronique Feipel, Gaël Deboeck, and Bruno Bonnechère
Wiley
Patients with chronic obstructive pulmonary disease (COPD) may demonstrate cognitive function and balance deterioration. These two phenomena are often realized simultaneously during daily living activities, where the risk of falling may be increased due to possible postural disturbance when focusing on a cognitive task during motion. Despite the high rate of falls in COPD, there is currently a lack of affordable clinical instruments to quantify the interaction between cognitive tasks and static balance in these patients. Therefore, this study aims to assess the balance perturbation induced by cognitive tasks using a new cost‐effective protocol which can easily be implemented in clinical settings.
Andrea Crespo, Sébastien Baillieul, Esther Marhuenda, Matteo Bradicich, Vasileios Andrianopoulos, Louvaris Zafeiris, Mathieu Marillier, and Isaac Almendros
European Respiratory Society (ERS)
The 2019 European Respiratory Society (ERS) International Congress took place in Madrid, Spain, and served as a platform to find out the latest advances in respiratory diseases research. The research aims are to understand the physiology and consequences of those diseases, as well as the improvement in their diagnoses, treatments and patient care. In particular, the scientific sessions arranged by ERS Assembly 4 provided novel insights into sleep-disordered breathing and new knowledge in respiratory physiology. This article, divided by session, will summarise the most relevant studies presented at the ERS International Congress. Each section has been written by Early Career Members specialising in the different fields of this interdisciplinary assembly.
Olivier Van Hove, Alain Van Muylem, Vasileios Andrianopoulos, Dimitri Leduc, Véronique Feipel, Gaël Deboeck, and Bruno Bonnechère
Elsevier BV
Vasileios Andrianopoulos, Rainer Gloeckl, Martina Boensch, Katharina Hoster, Tessa Schneeberger, Inga Jarosch, Rembert A. Koczulla, and Klaus Kenn
European Respiratory Society (ERS)
BackgroundPulmonary rehabilitation (PR) following lung transplantation (LTx) is considered part of the optimal treatment in chronic obstructive pulmonary disease (COPD) for favourable post-operative outcomes. We investigated the effects of a PR intervention in the post-transplant phase with regard to lung function, exercise responses and cognitive function in COPD LTx recipients.Methods24 COPD LTx recipients (mean±sdforced expiratory volume in 1 s 75±22% predicted) were assigned to a comprehensive 3-week inpatient PR programme. Changes from PR admission to discharge in lung function variables, 6-min walk test-derived outcomes and cognitive function were assessed and examined for several factors. The magnitude of changes was interpreted by effect size (ES).ResultsIn response to the PR intervention, LTx recipients had improved lung function with regard to diffusing capacity of the lung for carbon monoxide (+4.3%; p=0.012) and static hyperinflation (residual volume/total lung capacity −2.3%; p=0.017), increased exercise capacity (6-min walk test +86 m; p<0.001), and had small to large improvements (ES range 0.23–1.00; all p≤0.34) in 50% of the administered cognitive tests. Learning skills and memory ability presented the greatest benefits (ES composite scores 0.62 and 0.31, respectively), which remained similar after stratification by single or bilateral LTx and sex.ConclusionsPR is an effective treatment for LTx recipients in the post-transplant phase, improving lung function, exercise responses, and domains of cognitive function of learning, memory and psychomotor speed. PR may facilitate the course of post-operative treatment and should be recommended in LTx.
Zafeiris Louvaris, Stavroula Spetsioti, Vasileios Andrianopoulos, Nikolaos Chynkiamis, Helmut Habazettl, Harrieth Wagner, Spyros Zakynthinos, Peter D. Wagner, and Ioannis Vogiatzis
Wiley
Impedance cardiography (IC) derived from morphological analysis of the thoracic impedance signal is now commonly used for noninvasive assessment of cardiac output (CO) at rest and during exercise. However, in Chronic Obstructive Pulmonary Disease (COPD), conflicting findings put its accuracy into question.
Rainer Gloeckl, Vasileios Andrianopoulos, Antje Stegemann, Julian Oversohl, Tessa Schneeberger, Ursula Schoenheit‐Kenn, Wolfgang Hitzl, Michael Dreher, A. Rembert Koczulla, and Klaus Kenn
Wiley
Patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnic respiratory failure (CHRF) characteristically have exercise intolerance and limitations in performing conventional training. Therefore, the aim of this study was to investigate the acute effects of non‐invasive ventilation (NIV) as a supportive tool during exercise in CHRF.
Lowie E.G.W. Vanfleteren, Iñigo Ojanguren, Claire M. Nolan, Frits M.E. Franssen, Vasileios Andrianopoulos, Aleksandar Grgic, Marlies van Dijk, Dirk Jan Slebos, Luke Daines, Janwillem W.H. Kocks,et al.
European Respiratory Society (ERS)
This article contains highlights and a selection of the scientific advances from the European Respiratory Society's Clinical Assembly (Assembly 1 and its five respective groups) that were presented at the 2018 European Respiratory Society International Congress in Paris, France. The most relevant topics from each of the groups will be discussed, covering a wide range of areas including clinical problems, rehabilitation and chronic care, thoracic imaging, interventional pulmonology, and general practice and primary care. The newest research, actual data and highlight sessions will be discussed.
Vasileios Andrianopoulos, Ioannis Vogiatzis, Rainer Gloeckl, Robert Bals, Rembert A. Koczulla, and Klaus Kenn
Elsevier BV
Nicolas Kahn, Evgeni Mekov, Laura Fregonese, Vasileios Andrianopoulos, Frits M.E. Franssen, Aleksandar Grgic, Johan Coolen, Peter I. Bonta, Daniela Gompelmann, Jouke T. Annema,et al.
European Respiratory Society (ERS)
This article contains highlights and a selection of the scientific advances from the European Respiratory Society's Clinical Assembly (Assembly 1 and its six respective groups) that were presented at the 2017 European Respiratory Society International Congress in Milan, Italy. The most relevant topics from each of the groups will be discussed, covering a wide range of areas including clinical problems, rehabilitation and chronic care, thoracic imaging, interventional pulmonology, diffuse and parenchymal lung diseases, and general practice and primary care. In this comprehensive review, the newest research and actual data as well as award-winning abstracts and highlight sessions will be discussed.
Nicolas Kahn, Ioannis Tomos, Vasileios Andrianopoulos, Husevin Arikan, Anne van der Does, Isaac Almendros, Sara Bonvivi, Ann Morgan, Raffaella Nenna, Dimitrios Magouliotis,et al.
European Respiratory Society (ERS)
The 2017 ERS International Congress was, as always, well organised, providing participants with a good mixture of translational and clinical science. Early career members were very well represented in thematic poster, poster discussion and oral presentation sessions and were also actively involved in chairing sessions. The efforts of the Early Career Members Committee (ECMC) to increase the number of early career members included in the competence list (the list of early career members with an interest in being more actively involved in the society) paid off immensely, because the number of early career members registered improved hugely across all assemblies after the Congress. Several newly registered early career members have collated some highlights of the Congress for their assemblies, which should be of interest to all members. As assemblies 12 and 13 are new, there is no report from assembly 12 as there is not yet, at the time of writing, an early career member representative for this newly created assembly. .@EarlyCareerERS reflect on the highlights from the #ERSCongress 2017
http://ow.ly/klLS30gAN49
Nicolas Kahn, Vasileios Andrianopoulos, Evgeni Mekov, and Felix J. F. Herth
AME Publishing Company
This review highlights a selection of abstracts from the 2017 ERS International Congress in Milan presented by the clinical assembly's groups of interventional pulmonology, general practice and primary care and rehabilitation and chronic care. Attention is brought to the increasing burden of disease of COPD and end-stage emphysema patients in China. The considerable efforts of Chinese pulmonary centers to conduct multicenter, randomized and controlled trials, investigating the possibilities of bronchoscopic lung volume reduction is underlined in the review. Furthermore, the key objectives of asthma management are stressed. We point out presentations emphasizing on achieving good control of daily symptoms and reducing the risk of asthma exacerbations. The findings of a randomized clinical trial evaluating the role of oxygen supplementation in rehabilitation therapy of COPD patients are analyzed. Additionally, another randomized clinical trial researching the influence of whole body vibration training (WBVT) in long-term (>1 year) lung transplant patients are discussed.
Rainer Gloeckl, Inga Jarosch, Ulrike Bengsch, Magdalena Claus, Tessa Schneeberger, Vasileios Andrianopoulos, Jeffrey W. Christle, Wolfgang Hitzl, and Klaus Kenn
Elsevier BV
Vasileios Andrianopoulos, Rainer Gloeckl, Ioannis Vogiatzis, and Klaus Kenn
European Respiratory Society (ERS)
Cognitive impairment is highly prevalent in patients with COPD and demonstrates multiple detrimental effects on many aspects of patient state and therapeutic outcomes. It is attributed to several overlapping pathophysiological factors, with the most common being the low level of oxygen saturation due to respiratory insufficiency. Despite the impact of cognitive impairment on clinical outcomes, the screening for coexisting cognitive deficits which may interfere with the successful progress of respiratory treatment is yet neglected. There is a special consideration that cognitive deficits should be taken into account when developing respiratory therapy plans. Cognitively impaired patients are likely to require more support and have need of an individualised respiratory care plan which can also be beneficial for their cognitive deficits. Pulmonary rehabilitation as a multidisciplinary approach could be prioritised for COPD patients with cognitive impairment.Educational aimsTo illustrate the common signs of cognitive impairment and define potential associations between lung and cognitive dysfunction.To illustrate the potential influence of cognitive deficits on the optimal progress of respiratory therapy.To illustrate the importance of cognitive evaluation as part of a comprehensive clinical assessment for patients suspected of suffering cognitive impairment.
Vasileios Andrianopoulos, Lowie E.G.W Vanfleteren, Inga Jarosch, Rainer Gloeckl, Tessa Schneeberger, Emiel F.M. Wouters, Martijn A. Spruit, and Klaus Kenn
Elsevier BV
Vasileios Andrianopoulos, Bartolome R. Celli, Frits M.E. Franssen, Victor M. Pinto-Plata, Peter M.A. Calverley, Lowie E.G.W. Vanfleteren, Ioannis Vogiatzis, Jørgen Vestbo, Alvar Agusti, Per S. Bakke,et al.
Elsevier BV
Vasileios Andrianopoulos and Ioannis Vogiatzis
Springer International Publishing
Vasileios Andrianopoulos, Emiel F.M. Wouters, Victor M. Pinto-Plata, Lowie E.G.W. Vanfleteren, Per S. Bakke, Frits M.E. Franssen, Alvar Agusti, William MacNee, Stephen I. Rennard, Ruth Tal-Singer,et al.
Elsevier BV
Vasileios Andrianopoulos, Anne E Holland, Sally J Singh, Frits ME Franssen, Herman-Jan Pennings, Arent J Michels, Frank WJM Smeenk, Ioannis Vogiatzis, Emiel FM Wouters, and Martijn A Spruit
SAGE Publications
The use of different 6-min walk distance (6MWD) reference equations probably results in different predicted 6MWD reference values. We wished to investigate the impact of several 6MWD reference equations for adults in patients with chronic obstructive pulmonary disease (COPD) and factors accountable for different 6MWD% predicted values. Twenty-two 6MWD reference equations were applied to a data set of 2757 patients with COPD. The predicted 6MWD reference value of Troosters and colleagues was used as the point of reference. Four out of 21 remaining equations resulted in comparable 6MWD% predicted, 16 equations resulted in significantly higher 6MWD% predicted and 1 equation resulted in a significantly lower 6MWD% predicted. Similar differences in 6MWD% predicted were observed after stratification by sex. Body mass index and global initiative for chronic obstructive lung disease (GOLD) stage classification demonstrated varying results within and between the groups; 9 out of 21 equations resulted in comparable 6MWD% predicted in underweight patients but only 1 equation demonstrated comparable result in obese. Eight equations in GOLD I, whilst 5 out of 21 equations in GOLD IV resulted in comparable 6MWD% predicted. Existing 6MWD reference equations will give varying results. The choice of 6MWD reference equation should consider the consistency of 6-min walk test operating procedures and at least be specific for the country/region of origin.
Ioannis Vogiatzis, Helmut Habazettl, Zafeiris Louvaris, Vasileios Andrianopoulos, Harrieth Wagner, Spyros Zakynthinos, and Peter D. Wagner
American Physiological Society
Heterogeneity in the distribution of both blood flow (Q̇) and O2consumption (V̇o2) has not been assessed by near-infrared spectroscopy in exercising normal human muscle. We used near-infrared spectroscopy to measure the regional distribution of Q̇ and V̇o2in six trained cyclists at rest and during constant-load exercise (unloaded pedaling, 20%, 50%, and 80% of peak Watts) in both normoxia and hypoxia (inspired O2fraction = 0.12). Over six optodes over the upper, middle, and lower vastus lateralis, we recorded 1) indocyanine green dye inflow after intravenous injection to measure Q̇; and 2) fractional tissue O2saturation (StiO2) to estimate local V̇o2-to-Q̇ ratios (V̇o2/Q̇). Varying both exercise intensity and inspired O2fraction provided a (directly measured) femoral venous O2saturation range from about 10 to 70%, and a correspondingly wide range in StiO2. Mean Q̇-weighted StiO2over the six optodes related linearly to femoral venous O2saturation in each subject. We used this relationship to compute local muscle venous blood O2saturation from StiO2recorded at each optode, from which local V̇o2/Q̇ could be calculated by the Fick principle. Multiplying regional V̇o2/Q̇ by Q̇ yielded the corresponding local V̇o2. While six optodes along only in one muscle may not fully capture the extent of heterogeneity, relative dispersion of both Q̇ and V̇o2was ∼0.4 under all conditions, while that for V̇o2/Q̇ was minimal (only ∼0.1), indicating in fit young subjects 1) a strong capacity to regulate Q̇ according to regional metabolic need; and 2) a likely minimal impact of heterogeneity on muscle O2availability.
Anne E. Holland, Martijn A. Spruit, Thierry Troosters, Milo A. Puhan, Véronique Pepin, Didier Saey, Meredith C. McCormack, Brian W. Carlin, Frank C. Sciurba, Fabio Pitta,et al.
European Respiratory Society (ERS)
Field walking tests are commonly employed to evaluate exercise capacity, assess prognosis and evaluate treatment response in chronic respiratory diseases. In recent years, there has been a wealth of new literature pertinent to the conduct of the 6-min walk test (6MWT), and a growing evidence base describing the incremental and endurance shuttle walk tests (ISWT and ESWT, respectively). The aim of this document is to describe the standard operating procedures for the 6MWT, ISWT and ESWT, which can be consistently employed by clinicians and researchers.The Technical Standard was developed by a multidisciplinary and international group of clinicians and researchers with expertise in the application of field walking tests. The procedures are underpinned by a concurrent systematic review of literature relevant to measurement properties and test conduct in adults with chronic respiratory disease.Current data confirm that the 6MWT, ISWT and ESWT are valid, reliable and responsive to change with some interventions. However, results are sensitive to small changes in methodology. It is important that two tests are conducted for the 6MWT and ISWT.This Technical Standard for field walking tests reflects current evidence regarding procedures that should be used to achieve robust results.