Yasser Hussein Issa Mohammed

Scopus Publications

Synthesis of substituted biphenyls and in vitro evaluation of antimicrobial and anti-biofilm activities supported by in silico ADMET prediction
Saad Alghamdi, Ahmed Hassen Shntaif, Yasser Hussein Issa Mohammed
Plos One, 2026
Antibiotic resistance represents a critical global health challenge, necessitating the development of innovative antimicrobial agents. This research focuses on the design and evaluation of antimicrobial compounds through chemical synthesis and computational methodologies. Biaryl analogues were synthesized via Suzuki coupling reactions and assessed for in vitro antimicrobial activity against Staphylococcus aureus , Escherichia coli , and Candida albicans . Computational approaches, including molecular docking, crystal structure optimization, and toxicity profiling, were employed to explore potential molecular interactions and preliminary safety profiles. The synthesized biaryl derivatives demonstrated variable antimicrobial activity across the tested microorganisms. Among these, 2-methoxy-4’-nitro-1,1’-biphenyl (3i) exhibited the most potent antibacterial activity against both Gram-positive and Gram-negative strains. As a preliminary screening, these findings highlight the potential of selected biaryl derivatives as lead candidates for further investigation. Future studies are required to validate activity against resistant strains and to evaluate efficacy in vivo .
Synthesis of novel phenoxyacetohydrazide compounds and evaluation therapeutic potential exhibit as anti-inflammatory and anti-angiogenic
Yasser Hussein Issa Mohammed, Ahmed Hassen Shntaif, Saad Alghamdi, Ahd A. Mansour, Naeem F. Qusty, et al.
Plos One, 2025
This study aimed to design, synthesize, and evaluate novel morpholine-substituted phenoxyacetohydrazide derivatives as potential anti-inflammatory and anti-angiogenic agents. The compounds were synthesized and characterized by FTIR, NMR, mass spectrometry, and elemental analysis. In silico molecular docking revealed that compound 6e exhibited strong binding affinities toward vascular endothelial growth factor (VEGF), cyclooxygenase-1 (COX-1), and cyclooxygenase-2 (COX-2), with docking scores of –13.1622, –12.5301, and –12.6705 (kcal/mol) respectively. The in vitro anti-inflammatory activity, assessed via the human red blood cell (HRBC) membrane stabilization assay, showed that compound 6e achieved an IC₅₀ value of 155 μg/mL, indicating potent efficacy. Additionally, 6e demonstrated significant anti-angiogenic activity in both in vivo and ex vivo chick chorioallantoic membrane (CAM) models, inhibiting VEGF-induced angiogenesis in a dose-dependent manner and markedly reducing microvessel density and vessel length. In a rat model of alkali-induced corneal neovascularization, compound 6e substantially suppressed neovascular growth. Moreover, in the carrageenan-induced paw edema model, it effectively reduced edema, neutrophil infiltration, and myeloperoxidase activity. Collectively, these findings position compound 6e as a promising dual-action therapeutic candidate for treating chronic inflammation and pathological angiogenesis. This study underscores the potential of systematically designed phenoxyacetohydrazide scaffolds as multi-targeted therapeutic agents.
Synthesis and multifaceted evaluation of novel AgCZ nanocomposite for targeted anti-angiogenic cancer therapy
Yasser Hussein Issa Mohammed, Ahmed Hassen Shntaif, Ahd A. Mansour, Samia Alrabghi, Saad Alghamdi, et al.
Scientific Reports, 2024
Synthesis and evaluation of pyridine-3-carboxamide analogs as effective agents against bacterial wilt in tomatoes
Yasser Hussein Issa Mohammed, Israa M. Shamkh, Ahmed Hassen Shntaif, Muhammad Sufyan, Md Tabish Rehman, et al.
Scientific Reports, 2024
This study focused on developing novel pyridine-3-carboxamide analogs to treat bacterial wilt in tomatoes caused by Ralstonia solanacearum. The analogs were synthesized through a multistep process and their structures confirmed using spectroscopy. Molecular docking studies identified the most potent analog from the series. A specific analog, compound 4a, was found to significantly enhance disease resistance in tomato plants infected with R. solanacearum. The structure–activity relationship analysis showed the positions and types of substituents on the aromatic rings of compounds 4a–i strongly influenced their biological activity. Compound 4a, with a chloro group at the para position on ring C and hydroxyl group at the ortho position on ring A, was exceptionally effective against R. solanacearum. When used to treat seeds, the analogs displayed remarkable efficacy, especially compound 4a which had specific activity against bacterial wilt pathogens. Compound 4a also promoted vegetative and reproductive growth of tomato plants, increasing seed germination and seedling vigor. In plants mechanically infected with bacteria, compound 4a substantially reduced the percentage of infection, pathogen quantity in young tissue, and disease progression. The analogs were highly potent due to their amide linkage. Molecular docking identified the best compounds with strong binding affinities. Overall, the strategic design and synthesis of these pyridine-3-carboxamide analogs offers an effective approach to targeting and controlling R. solanacearum and bacterial wilt in tomatoes.
Unveiling the hidden culprits: exploring fungal infections and risk factors in chronic suppurative inflammation of the middle ear
Romanian Journal of Diabetes Nutrition and Metabolic Diseases, 2024
The role of thrombolytic protein therapy in the prevention of microvascular complications in non-insulin-dependent diabetes mellitus: an integrative approach
Romanian Journal of Diabetes Nutrition and Metabolic Diseases, 2024
Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl)benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies
Yasser Hussein Issa Mohammed, Israa M. Shamkh, Nahed S. Alharthi, Mohammed A. Shanawaz, Hind A. Alzahrani, et al.
Scientific Reports, 2023
Cancer and different types of tumors are still the most resistant diseases to available therapeutic agents. Finding a highly effective anticancer drug is the first target and concern of thousands of drug designers. In our attempts to address this concern, a new pyrazine derivative, 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl)benzyl]urea (BPU), was designed via structural optimization and synthesized to investigate its anticancer/antitumor potential. The in-vitro anticancer properties of BPU were evaluated by MTT assay using selected cell lines, including the Jurkat, HeLa, and MCF-7 cells. The Jurkat cells were chosen to study the effect of BPU on cell cycle analysis using flow cytometry technique. BPU exhibited an effective cytotoxic ability in all the three cell lines assessed. It was found to be more prominent with the Jurkat cell line (IC50 = 4.64 ± 0.08 µM). When it was subjected to cell cycle analysis, this compound effectively arrested cell cycle progression in the sub-G1 phase. Upon evaluating the antiangiogenic potential of BPU via the in-vivo/ex-vivo shell-less chick chorioallantoic membrane (CAM) assays, the compound demonstrated very significant findings, revealing a complementary supportive action for the compound to act as a potent anticancer agent through inhibiting blood vessel formation in tumor tissues. Moreover, the docking energy of BPU computationally scored − 9.0 kcal/mol with the human matrix metalloproteinase 2 (MMP-2) and − 7.8 kcal/mol with the human matrix metalloproteinase 9 (MMP-9), denoting promising binding results as compared to the existing drugs for cancer therapy. The molecular dynamics (MD) simulation outcomes showed that BPU could effectively bind to the previously-proposed catalytic sites of both MMP-2 and MMP-9 enzymes with relatively stable statuses and good inhibitory binding abilities and parameters. Our findings suggest that the compound BPU could be a promising anticancer agent since it effectively inhibited cell proliferation and can be selected for further in-vitro and in-vivo investigations. In addition, the current results can be extensively validated by conducting wet-lab analysis so as to develop novel and better derivatives of BPU for cancer therapy with much less side effects and higher activities.
Green Synthesis of Zinc Oxide Nanoparticles Using Cymbopogon citratus Extract and Its Antibacterial Activity
Yasser Hussein Issa Mohammed, Saad Alghamdi, Basit Jabbar, Dina Marghani, Saba Beigh, et al.
ACS Omega, 2023
Antibiotic susceptibility and bioremediation potential of probiotic bacteria against lead and cadmium isolated from yogurt
Pakistan Journal of Pharmaceutical Sciences, 2023
Optimization of different growth parameters for maximum production of bioactive crude metabolites by Aspergillus fumigatus
Pakistan Journal of Pharmaceutical Sciences, 2023
Isoform switching leads to downregulation of cytokine producing genes in estrogen receptor positive breast cancer
Mohammad Shahbaz Khan, Waqar Hanif, Nada Alsakhen, Basit Jabbar, Israa M. Shamkh, et al.
Frontiers in Genetics, 2023
Neuroprotective, lifespan, memory enhancing potential, and molecular docking studies of natural compound from Curculigo orchioides Gaertn.,: A study on Alzheimer's disease model of Appl-GAL4 Drosophila melanogaster
Pratap GK, Pramod G Nagaraju, Ananda Danagoudar, Chandrashekhar G. Joshi, Poornima Priyadarshini CG, et al.
South African Journal of Botany, 2022
Experimental and computational studies on the synthesis and structural characterization of 2-(4-chlorophenoxy)-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide
Hamdi Hamid Sallam, Yasser Hussien Issa Mohammed, Fares Hezam Al-Ostoot, P. Akhileshwari, M.A. Sridhar, et al.
Journal of Molecular Structure, 2022
Synthesis, elucidation, DFT computations, Hirshfeld surface analysis and docking study of 6-chloro-3-[(4-fluoro-phenoxy)methyl][1, 2, 4]triazolo[4,3-b]pyridazine against fungi pathogen
Hamdi Hamid Sallam, Yasser Hussien Issa Mohammed, Fares Hezam Al-Ostoot, P. Akhileshwari, M. A. Sridhar, et al.
Molecular Crystals and Liquid Crystals, 2022
Synthesis, crystal structure characterization, DFT calculations, Hirshfeld surface analysis and 3D energy frameworks of triazole pyridazine derivatives: Theoretical and experimental studies
Hamdi Hamid Sallam, Yasser Hussien Issa Mohammed, Fares Hezam Al-Ostoot, Sridhar M. A., Shaukath Ara Khanum
Journal of Molecular Structure, 2021
Synthesis, structure analysis, DFT calculations, Hirshfeld surface studies, and energy frameworks of 6-Chloro-3-[(4-chloro-3-methylphenoxy)methyl][1,2,4]triazolo[4,3-b]pyridazine
Hamdi Hamid Sallam, Yasser Hussien Eissa Mohammed, Fares Hezam Al-Ostoot, M.A. Sridhar, Shaukath Ara Khanum
Journal of Molecular Structure, 2021
Synthesis, structural characterization, and DFT studies of anti-cancer drug N-(2-Aminophenyl)-2-(4-bromophenoxy)acetamide
S.N. Chandana, Fares Hezam Al-Ostoot, Yasser Hussein Eissa Mohammed, Tareq N. Al-Ramadneh, P. Akhileshwari, et al.
Heliyon, 2021
Molecular docking and synthesis of caffeic acid analogous and its anti-inflammatory, analgesic and ulcerogenic studies
Fares Hezam Al-Ostoot, Zabiulla, S. Grisha, Yasser Hussein Eissa Mohammed, H.K Vivek, et al.
Bioorganic and Medicinal Chemistry Letters, 2021
Synthesis, structural analysis, Hirshfeld surface analysis, DFT calculations, in vitro and docking study on antioxidant activity of 6-chloro-3-[(4-methylphenoxy) methyl] [1,2,4] triazolo[4,3-b]pyridazine
Hamdi Hamid Sallam, Yasser Hussien Eissa Mohammed, Geetha D. V., Fares Hezam Al-Ostoot, Sridhar M. A., et al.
Molecular Crystals and Liquid Crystals, 2021
N-(4-bromobenzylidene)-2,3-dihydrobenzo[b][1,4]dioxin-6-amine: Synthesis, crystal structure, docking and in-vitro inhibition of PLA2
M.K. Hema, R.R. ArunRenganathan, S. Nanjundaswamy, C.S. Karthik, Yasser Hussein Issa Mohammed, et al.
Journal of Molecular Structure, 2020
Design-based synthesis, molecular docking analysis of an anti-inflammatory drug, and geometrical optimization and interaction energy studies of an indole acetamide derivative
Fares Hezam Al-Ostoot, D.V. Geetha, Yasser Hussein Eissa Mohammed, P. Akhileshwari, M.A. Sridhar, et al.
Journal of Molecular Structure, 2020
Effect of o-difluoro and p-methyl substituents on the structure, optical properties and anti-inflammatory activity of phenoxy thiazole acetamide derivatives: Theoretical and experimental studies
Hussien Ahmed Khamees, Yasser Hussein Eissa Mohammed, Ananda S, Fares Hezam Al-Ostoot, Sangappa Y, et al.
Journal of Molecular Structure, 2020
Synthesis of dihydrazones as potential anticancer and DNA binding candidates: A validation by molecular docking studies
Malavalli B. Sridhara, Kadalipura P. Rakesh, Honnayakanahalli M. Manukumar, Chavalmane S. Shantharam, Hamse K. Vivek, et al.
Anti Cancer Agents in Medicinal Chemistry, 2020
Design, structural, C–H….H–C supramolecular interactions and computational investigations of Cd(N∩N″)X2 complexes based on an asymmetrical 1,2-diamine ligand: physicochemical and thermal analysis
Ismail Warad, Khaled Alkanad, Mohammed Suleiman, Karthik Kumara, Anas Al-Ali, et al.
Journal of Coordination Chemistry, 2019
Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic agents
Zabiulla, A.R. Gulnaz, Yasser Hussein Eissa Mohammed, Shaukath Ara Khanum
Bioorganic Chemistry, 2019
Correction to: Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma (Medicinal Chemistry Research, (2019), 28, 8, (1132-1160), 10.1007/s00044-019-02357-x)
Zabiulla, Vikas H. Malojirao, Yasser Hussein Eissa Mohammed, Prabhu Thirusangu, B. T. Prabhakar, et al.
Medicinal Chemistry Research, 2019
Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma
Zabiulla Zabiulla, Vikas H. Malojirao, Yasser Hussein Eissa Mohammed, Prabhu Thirusangu, B. T. Prabhakar, et al.
Medicinal Chemistry Research, 2019
Radical scavenging and anti-inflammatory activities of (hetero)arylethenesulfonyl fluorides: Synthesis and structure-activity relationship (SAR)and QSAR studies
Ying Jiang, K.P. Rakesh, Njud S. Alharbi, H.K. Vivek, H.M. Manukumar, et al.
Bioorganic Chemistry, 2019
Synthesis, in silico study and in vitro anti-microbial evaluation of some new N-benzoyl-N'-[2-(4-chloro-phenoxy)-acetyl]-hydrazides analogs
Journal of Applied Pharmaceutical Science, 2019
Molecular Structure, DFT, Vibrational Spectra with Fluorescence Effect, Hirshfeld Surface, Docking Simulation and Antioxidant Activity of Thiazole Derivative
Hussien A. Khamees, Yasser H. E. Mohammed, Ananda Swamynayaka, Fares H. Al‐Ostoot, Yusuf Sert, et al.
Chemistryselect, 2019
Synthesis, crystal structure and 3D energy frameworks of ethyl 2-[5-nitro-2-oxopyridine-1(2H)-yl] acetate: Hirshfeld surface analysis and DFT calculations
Karthik Kumara, Fares Hezam Al-Ostoot, Yasser Hussein Eissa Mohammed, Shaukath Ara Khanum, Neratur Krishnappagowda Lokanath
Chemical Data Collections, 2019
Innovative nano-carriers in anticancer drug delivery-a comprehensive review
Peng Dong, K.P. Rakesh, H.M. Manukumar, Yasser Hussein Eissa Mohammed, C.S. Karthik, et al.
Bioorganic Chemistry, 2019
Synthesis, Elucidation, Hirshfeld surface analysis, and DFT calculations of 4-chloro-N-[2-(2-1H-indol-3-yl-acetylamino)-phenyl]-benzamide
D.V. Geetha, Fares Hezam Al-Ostoot, Yasser Hussein Eissa Mohammed, M.A. Sridhar, Shaukath Ara Khanum, et al.
Journal of Molecular Structure, 2019
Synthesis, structure and molecular docking analysis of an anticancer drug of N-(2-aminophenyl)-2-(2-isopropylphenoxy) acetamide
Gopal Sharma, Sumati Anthal, D. V. Geetha, Fares Hezam Al-Ostoot, Yasser Hussein Eissa Mohammed, et al.
Molecular Crystals and Liquid Crystals, 2018
Vision for medicine: Staphylococcus aureus biofilm war and unlocking key's for anti-biofilm drug development
Yasser Hussein Eissa Mohammed, H.M. Manukumar, K.P. Rakesh, C.S. Karthik, P. Mallu, et al.
Microbial Pathogenesis, 2018
Role of BP*C@AgNPs in Bap-dependent multicellular behavior of clinically important methicillin-resistant Staphylococcus aureus (MRSA) biofilm adherence: A key virulence study
Xu Zhang, H.M. Manukumar, K.P. Rakesh, C.S. Karthik, H.S. Nagendra Prasad, et al.
Microbial Pathogenesis, 2018
Synthesis and amelioration of inflammatory paw edema by novel benzophenone appended oxadiazole derivatives by exhibiting cyclooxygenase-2 antagonist activity
Naveen Puttaswamy, Vikas H. Malojiao, Yasser Hussein Eissa Mohammed, Ankith Sherapura, B.T. Prabhakar, et al.
Biomedicine and Pharmacotherapy, 2018
Crystal packing analysis of 1-(3,4-dimethoxyphenyl)-3-(4-bromophenyl)prop-2-en-1-one exhibiting a putative halogen bond C[sbnd]Br⋯O
Shankar Madan Kumar, Al-Ostoot Fares Hezam, B.C. Manjunath, Varija Raghu Shamprasad, Yasser Hussein Eissa Mohammed, et al.
Journal of Molecular Structure, 2018
The critical role of novel benzophenone analogs on tumor growth inhibition targeting angiogenesis and apoptosis
Yasser Hussein Eissa Mohammed, Shaukath Ara Khanum
Medchemcomm, 2018
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death
Yasser Hussein Eissa Mohammed, Vikas H. Malojirao, Prabhu Thirusangu, Mohammed Al-Ghorbani, B.T. Prabhakar, et al.
European Journal of Medicinal Chemistry, 2018
Synthesis, characterization, crystal structure and Hirshfeld surface analysis of o-tolyloxy acetic acid (1H-indol-3-yl-methylene)-hydrazide
Mamatha S.V., S. Naveen, Zabiulla, Yasser Hussein Eissa Mohammed, N.K. Lokanath, et al.
Chemical Data Collections, 2017
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases
Yasser Hussein Eissa Mohammed, Prabhu Thirusangu, Zabiulla, Vigneshwaran V, Prabhakar B.T, et al.
Biomedicine and Pharmacotherapy, 2017
Synthesis, characterization, crystal structure and Hirshfeld surface analysis of ethyl 2-(2-oxo-2H-chromen-4-yloxy) acetate
Mahima Jyothi, Naveen Shivalingegowda, Zabiulla, Yasser Hussein Issa Mohammed, Neratur Krishnappagowda Lokanath, et al.
Chemical Data Collections, 2017
Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development
Mohammed Al-Ghorbani, Prabhu Thirusangu, H.D. Gurupadaswamy, V. Vigneshwaran, Yasser H.E. Mohammed, et al.
Bioorganic Chemistry, 2017
Evaluation of antioxidant activity of locally available green teas in India
Der Pharmacia Lettre, 2016
Evaluation of in vitro antioxidant activity of benzophenone-pyridine analogues
Der Pharma Chemica, 2016
Synthesis, characterization, Hirshfeld analysis, crystal and molecular structure studies of 2,6-difluoro phenoxy acetic acid
Der Pharma Chemica, 2016
Comparative evaluation of antimicrobial and antioxidant efficacy of 7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo [3,2-a] pyrimidin-5-one analogues - An in-vitro study
Der Pharmacia Lettre, 2015

RECENT SCHOLAR PUBLICATIONS

Design, synthesis, and anticancer activity of phenoxyacetohydrazide derivatives in burkitt lymphoma
YHI Mohammed, S Alghamdi, HA Almasmoum, AH Shntaif, N Suhail, ...
Scientific Reports , 2026
2026
Synthesis of substituted biphenyls and in vitro evaluation of antimicrobial and anti-biofilm activities supported by in silico ADMET prediction
S Alghamdi, AH Shntaif, YHI Mohammed
Plos one 21 (4), e0346142 , 2026
2026
Morphological and Optical Analysis of α-Al2O3:Zn Nanoparticles
Eman Mohammed Ali Nassar, A.H. AL-Hammadi, Yasser Hussein Issa Mohammed
Sana’a University Journal of Applied Sciences and Technology 3 (6), 1408–1418. , 2025
2025
Correction: Synthesis of novel phenoxyacetohydrazide compounds and evaluation therapeutic potential exhibit as anti-inflammatory and anti-angiogenic
YHI Mohammed, AH Shntaif, S Alghamdi, AA Mansour, NF Qusty, ...
Plos one 20 (12), e0339331 , 2025
2025
Synthesis of novel phenoxyacetohydrazide compounds and evaluation therapeutic potential exhibit as anti-inflammatory and anti-angiogenic
YHI Mohammed, AH Shntaif, S Alghamdi, AA Mansour, NF Qusty, ...
Plos one 20 (9), e0330731 , 2025
2025
Citations: 3
Unveiling the hidden culprits: exploring fungal infections and risk factors in chronic suppurative inflammation of the middle ear
HM Alnahdi, YHI Mohammed
Romanian Journal of Diabetes Nutrition and Metabolic Diseases 31 (4), 433-440 , 2024
2024
Citations: 1
Synthesis and multifaceted evaluation of novel AgCZ nanocomposite for targeted anti-angiogenic cancer therapy
YHI Mohammed, AH Shntaif, AA Mansour, S Alrabghi, S Alghamdi, ...
Scientific Reports 14 (1), 29289 , 2024
2024
Citations: 6
Assessment of preoperative antibiotic prophylaxis in general surgery: A comparative study.
YHI Mohammed, M Abulfaraj
The Egyptian Journal of Surgery 43 (4), 1292-1297 , 2024
2024
Citations: 1
Apparatus for performing Docking studies
YHI Mohammed
IN Patent 214,447 , 2024
2024
The role of thrombolytic protein therapy in the prevention of microvascular complications in non-insulin-dependent diabetes mellitus: an integrative approach
HM Alnahdi, YHI Mohammed
Romanian Journal of Diabetes Nutrition and Metabolic Diseases 31 (2), 158-164 , 2024
2024
Citations: 2
Synthesis and evaluation of pyridine-3-carboxamide analogs as effective agents against bacterial wilt in tomatoes
YHI Mohammed, IM Shamkh, AH Shntaif, M Sufyan, MT Rehman, ...
Scientific Reports 14 (1), 11118 , 2024
2024
Citations: 7
Physicochemical Parameters and Heavy Metals in Groundwater from Hajjah Governorate, Yemen Current Challenges and Future Perspectives
YHI Mohammed
Journal of Bioremediation & Biodegradation 15 (1), 1-2 , 2024
2024
Assessing the Impact of Heavy Metals on Groundwater in Hajjah Yemen Current Issues and Future Strategies
AAA Halani, YHI Mohammed
2024
African Journal of Biological Sciences
MAE Mohammed, S Salmaoui, HK Ibrahim, MMA Al-Qudah, B Alubaka, ...
2024
Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl) benzyl] urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational …
YHI Mohammed, IM Shamkh, NS Alharthi, MA Shanawaz, HA Alzahrani, ...
Scientific Reports 13 (1), 22824 , 2023
2023
Citations: 28
Protective Effects of Omega-3 Fatty Acids Against Cisplatin Induced Hepatocellular Damage and Oxidative Stress in Rats
T ALRAMADNEH, HA Abu-Harirah, IA Saleh, RY Athamneh, M Abusalah, ...
2023
Citations: 1
Spectrophotometric Determination of Nickel and Cobalt: Methods and Reagents
AK Goswami
Walter de Gruyter GmbH & Co KG , 2023
2023
Citations: 3
Green Synthesis of Zinc Oxide Nanoparticles Using Cymbopogon citratus Extract and Its Antibacterial Activity
YHI Mohammed, S Alghamdi, B Jabbar, D Marghani, S Beigh, ...
ACS omega 8 (35), 32027-32042 , 2023
2023
Citations: 93
A Hands-On Training Manual: Building Practical Skills for Success in Pharmaceutical Formulation and Analysis
YHI Mohammed
Scholars' Press 10, ‎92 pages , 2023
2023
Revolutionizing Therapeutics: Synthesizing Substituted Biphenyls and Assessing Their Antimicrobial Properties, ADMET Properties, and Biofilm Inhibition Potential
S Alghamdi, YHI Mohammed
2023

MOST CITED SCHOLAR PUBLICATIONS

Novel green biomimetic approach for synthesis of ZnO-Ag nanocomposite; antimicrobial activity against food-borne pathogen, biocompatibility and solar photocatalysis
M Zare, K Namratha, S Alghamdi, YHE Mohammad, A Hezam, M Zare, ...
Scientific reports 9 (1), 8303 , 2019
2019
Citations: 279
Innovative nano-carriers in anticancer drug delivery-a comprehensive review
P Dong, KP Rakesh, HM Manukumar, YHE Mohammed, CS Karthik, ...
Bioorganic chemistry 85, 325-336 , 2019
2019
Citations: 193
Vision for medicine: Staphylococcus aureus biofilm war and unlocking key's for anti-biofilm drug development
YHE Mohammed, HM Manukumar, KP Rakesh, CS Karthik, P Mallu, ...
Microbial pathogenesis 123, 339-347 , 2018
2018
Citations: 121
Detection and determination of stability of the antibiotic residues in cow’s milk
M Kurjogi, YH Issa Mohammad, S Alghamdi, M Abdelrahman, P Satapute, ...
PloS one 14 (10), e0223475 , 2019
2019
Citations: 109
Green Synthesis of Zinc Oxide Nanoparticles Using Cymbopogon citratus Extract and Its Antibacterial Activity
YHI Mohammed, S Alghamdi, B Jabbar, D Marghani, S Beigh, ...
ACS omega 8 (35), 32027-32042 , 2023
2023
Citations: 93
Role of BP* C@ AgNPs in Bap-dependent multicellular behavior of clinically important methicillin-resistant Staphylococcus aureus (MRSA) biofilm adherence: a key virulence study
X Zhang, HM Manukumar, KP Rakesh, CS Karthik, HSN Prasad, ...
Microbial pathogenesis 123, 275-284 , 2018
2018
Citations: 76
Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic agents
AR Gulnaz, YHE Mohammed, SA Khanum
Bioorganic Chemistry 92, 103220 , 2019
2019
Citations: 63
Design-based synthesis, molecular docking analysis of an anti-inflammatory drug, and geometrical optimization and interaction energy studies of an indole acetamide derivative
FH Al-Ostoot, DV Geetha, YHE Mohammed, P Akhileshwari, MA Sridhar, ...
Journal of Molecular Structure 1202, 127244 , 2020
2020
Citations: 52
Molecular structure, DFT, vibrational spectra with fluorescence effect, hirshfeld surface, docking simulation and antioxidant activity of thiazole derivative
HA Khamees, YHE Mohammed, A Swamynayaka, FH Al‐Ostoot, Y Sert, ...
ChemistrySelect 4 (15), 4544-4558 , 2019
2019
Citations: 51
Effect of o-difluoro and p-methyl substituents on the structure, optical properties and anti-inflammatory activity of phenoxy thiazole acetamide derivatives: theoretical and …
HA Khamees, YHE Mohammed, FH Al-Ostoot, S Alghamdi, SA Khanum, ...
Journal of Molecular Structure 1199, 127024 , 2020
2020
Citations: 46
Synthesis, crystal structure and 3D energy frameworks of ethyl 2-[5-nitro-2-oxopyridine-1 (2H)-yl] acetate: Hirshfeld surface analysis and DFT calculations
K Kumara, FH Al-Ostoot, YHE Mohammed, SA Khanum, NK Lokanath
Chemical Data Collections 20, 100195 , 2019
2019
Citations: 41
Radical scavenging and anti-inflammatory activities of (hetero) arylethenesulfonyl fluorides: synthesis and structure-activity relationship (SAR) and QSAR studies
Y Jiang, KP Rakesh, NS Alharbi, HK Vivek, HM Manukumar, ...
Bioorganic Chemistry 89, 103015 , 2019
2019
Citations: 39
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death
YHE Mohammed, VH Malojirao, P Thirusangu, M Al-Ghorbani, ...
European journal of medicinal chemistry 143, 1826-1839 , 2018
2018
Citations: 37
Synthesis, Elucidation, Hirshfeld surface analysis, and DFT calculations of 4-chloro-N-[2-(2-1H-indol-3-yl-acetylamino)-phenyl]-benzamide
DV Geetha, FH Al-Ostoot, YHE Mohammed, MA Sridhar, SA Khanum, ...
Journal of Molecular Structure 1178, 384-393 , 2019
2019
Citations: 34
Xanthone conjugated amino acids as potential anticancer and DNA binding agents: molecular docking, cytotoxicity and SAR studies
KP Rakesh, N Darshini, HM Manukumar, HK Vivek, MYH Eissa, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal … , 2018
2018
Citations: 31
Molecular docking and synthesis of caffeic acid analogous and its anti-inflammatory, analgesic and ulcerogenic studies
FH Al-Ostoot, S Grisha, YHE Mohammed, HK Vivek, SA Khanum
Bioorganic & Medicinal Chemistry Letters 33, 127743 , 2021
2021
Citations: 30
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases
YHE Mohammed, P Thirusangu, SA Khanum
Biomedicine & Pharmacotherapy 95, 375-386 , 2017
2017
Citations: 29
Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl) benzyl] urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational …
YHI Mohammed, IM Shamkh, NS Alharthi, MA Shanawaz, HA Alzahrani, ...
Scientific Reports 13 (1), 22824 , 2023
2023
Citations: 28
Immunological role of CD4 + CD28 null T lymphocytes, natural killer cells, and interferon-gamma in pediatric patients with sickle cell disease: relation to disease …
MS ElAlfy, AAM Adly, FSES Ebeid, DS Eissa, EAR Ismail, YH Mohammed, ...
Immunologic research 66 (4), 480-490 , 2018
2018
Citations: 26
Synthesis and amelioration of inflammatory paw edema by novel benzophenone appended oxadiazole derivatives by exhibiting cyclooxygenase-2 antagonist activity
N Puttaswamy, VH Malojiao, YHE Mohammed, A Sherapura, ...
Biomedicine & Pharmacotherapy 103, 1446-1455 , 2018
2018
Citations: 26

Yasser Hussein Issa Mohammed

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Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS