Yukimasa Shibata

Verified @gmail.com

Kwansei Gakuin University

April 1996 - March 1999 Japan Society for the Promotion of Science Special Research Fellow (DC1)
April 1999 - March 2000 Assistant, Department of Bioscience, Graduate School of Science, Nagoya Graduate University
April 2000 - March 2003 Postdoctoral Researcher, Faculty of Science, McGill University, Canada
April 2003 - March 2005 RIKEN CDB Researcher
April 2005 - March 2008 RIKEN CDB Basic Science Research Fellow
April 2008 - September 2010 RIKEN CDB Researcher
October 2010 - March 2014 Postdoctoral Researcher, Faculty of Science and Engineering, Kwansei Gakuin University
April 2014 - November 2018 Kwansei Gakuin University Faculty of Science and Engineering, Assistant Professor
November 2018 - March 2022 HIROTSU Bioscience Chief Researcher
April 2022 to present Assistant Professor, Faculty of Science and Engineering, Kwansei Gakuin University

EDUCATION

April 1990 - March 1994 Department of Molecular Biology, Faculty of Science, Nagoya University
April 1994 - March 1996: Master's Program, Department of Biology, Graduate School of Science, Nagoya University
April 1996 - March 1999 Doctoral course, Department of Life Sciences, Graduate School of Science, Nagoya University

RESEARCH, TEACHING, or OTHER INTERESTS

Genetics, Molecular Biology, Aging, Developmental Biology

616

Scholar Citations

10

Scholar h-index

11

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Endogenous chondroitin extends lifespan by inhibiting VHA-7-mediated tubular lysosome formation
    Y Shibata, Y Tanaka, S Mori, K Mitsuzumi, S Fujii, H Sasakura, Y Morioka, ...
    Scientific Reports 14 (1), 1-17 2024

  • Mutations in fibulin-1 and collagen IV suppress the short healthspan of mig-17/ADAMTS mutants in Caenorhabditis elegans
    Y Shibata, Y Huang, M Yoshida, K Nishiwaki
    PloS one 19 (7), e0305396 2024

  • Endogenous chondroitin extends the lifespan and healthspan in C. elegans
    Y Shibata, Y Tanaka, H Sasakura, Y Morioka, T Sassa, S Fujii, ...
    Scientific Reports 14 (1), 4813 2024

  • Repeat sequence corresponding to the nucleosome length at the opposite end of the pairing center on autosomes in C. elegans
    Y Shibata
    Micropublication Biology 2024 2024

  • Ribosomal protein mutation suppresses gonadal leader cell migration defects in mig-17/ADAMTS mutants in Caenorhabditis elegans
    HS Kim, K Mitsuzumi, S Kondo, R Yamaoka, S Ihara, H Otsuka, Y Kubota, ...
    bioRxiv, 2023.03. 28.534640 2023

  • Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans (vol 15, e0240571, 2020)
    A Imanishi, Y Aoki, M Kakehi, S Mori, T Takano, Y Kubota, HS Kim, ...
    PLOS ONE 16 (12) 2021

  • Correction: Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans
    A Imanishi, Y Aoki, M Kakehi, S Mori, T Takano, Y Kubota, HS Kim, ...
    PloS one 16 (12), e0261880 2021

  • Repulsive guidance molecule acts in axon branching in Caenorhabditis elegans
    K Tsutsui, HS Kim, C Yoshikata, K Kimura, Y Kubota, Y Shibata, C Tian, ...
    Scientific reports 11 (1), 1-11 2021

  • Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans
    A Imanishi, Y Aoki, M Kakehi, S Mori, T Takano, Y Kubota, HS Kim, ...
    Plos one 15 (12), e0240571 2020

  • Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration inCaenorhabditis elegans
    A Imanishi, Y Aoki, M Kakehi, S Mori, T Takano, Y Kubota, H Kim, ...
    2020

  • Maintenance of cell fates and regulation of the histone variant H3. 3 by TLK kinase in Caenorhabditis elegans
    Y Shibata, Y Seki, K Nishiwaki
    Biology open 8 (1), bio038448 2019

  • Maintenance of Cell Fates by Regulation of the Histone Variant H3. 3 in Caenorhabditis elegans
    Y Shibata, KI Nishiwaki
    Available at SSRN 3188453 2018

  • Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans
    Y Shibata, Y Kawakado, N Hori, K Tanaka, R Inoue, T Takano, Y Kubota, ...
    G3: Genes, Genomes, Genetics 6 (5), 1449-1457 2016

  • The BED finger domain protein MIG-39 halts migration of distal tip cells in Caenorhabditis elegans
    T Kikuchi, Y Shibata, HS Kim, Y Kubota, S Yoshina, S Mitani, K Nishiwaki
    Developmental biology 397 (2), 151-161 2015

  • Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex
    G Nishibuchi, Y Shibata, T Hayakawa, N Hayakawa, Y Ohtani, ...
    Journal of Biological Chemistry 289 (42), 28956-28970 2014

  • Maintenance of cell fates through acetylated histone and the histone variant H2A.z in C. elegans
    Y Shibata, K Nishiwaki
    Worm 3 (2), e29048 2014

  • The novel secreted factor MIG-18 acts with MIG-17/ADAMTS to control cell migration in Caenorhabditis elegans.
    KHS Kim HonSong, Y Kitano, M Mori, T Takano, TE Harbaugh, K Mizutani, ...
    2014

  • The Novel Secreted Factor MIG-18 Acts with MIG-17/ADAMTS to Control Cell Migration in Caenorhabditis elegans
    HS Kim, Y Kitano, M Mori, T Takano, TE Harbaugh, K Mizutani, ...
    Genetics 196 (2), 471-479 2014

  • HTZ-1/H2A. z and MYS-1/MYST HAT act redundantly to maintain cell fates in somatic gonadal cells through repression of ceh-22 in C. elegans
    Y Shibata, H Sawa, K Nishiwaki
    Development 141 (1), 209-218 2014

  • Multiple functions of PBRM-1/Polybromo- and LET-526/Osa-containing chromatin remodeling complexes in C. elegans development
    Y Shibata, M Uchida, H Takeshita, K Nishiwaki, H Sawa
    Developmental biology 361 (2), 349-357 2012

MOST CITED SCHOLAR PUBLICATIONS

  • Redox regulation of germline and vulval development in Caenorhabditis elegans
    Y Shibata, R Branicky, IO Landaverde, S Hekimi
    Science 302 (5651), 1779-1782 2003
    Citations: 138

  • Caenorhabditis elegans PlexinA, PLX-1, interacts with transmembrane semaphorins and regulates epidermal morphogenesis
    T Fujii, F Nakao, Y Shibata, G Shioi, E Kodama, H Fujisawa, S Takagi
    Development 129 (9), 2053-2063 2002
    Citations: 88

  • Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex
    G Nishibuchi, Y Shibata, T Hayakawa, N Hayakawa, Y Ohtani, ...
    Journal of Biological Chemistry 289 (42), 28956-28970 2014
    Citations: 86

  • EAT-20, a Novel Transmembrane Protein With EGF Motifs, Is Required for Efficient Feeding in Caenorhabditis elegans
    Y Shibata, T Fujii, JA Dent, H Fujisawa, S Takagi
    Genetics 154 (2), 635-646 2000
    Citations: 63

  • Phenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegans
    R Branicky, Y Shibata, J Feng, S Hekimi
    Genetics 159 (3), 997-1006 2001
    Citations: 62

  • The Plexin PLX-2 and the Ephrin EFN-4 Have Distinct Roles in MAB-20/Semaphorin 2A Signaling in Caenorhabditis elegans Morphogenesis
    F Nakao, ML Hudson, M Suzuki, Z Peckler, R Kurokawa, Z Liu, ...
    Genetics 176 (3), 1591-1607 2007
    Citations: 47

  • Multiple functions of PBRM-1/Polybromo- and LET-526/Osa-containing chromatin remodeling complexes in C. elegans development
    Y Shibata, M Uchida, H Takeshita, K Nishiwaki, H Sawa
    Developmental biology 361 (2), 349-357 2012
    Citations: 36

  • Double bromodomain protein BET-1 and MYST HATs establish and maintain stable cell fates in C. elegans
    Y Shibata, H Takeshita, N Sasakawa, H Sawa
    Development 137 (7), 1045-1053 2010
    Citations: 32

  • HTZ-1/H2A. z and MYS-1/MYST HAT act redundantly to maintain cell fates in somatic gonadal cells through repression of ceh-22 in C. elegans
    Y Shibata, H Sawa, K Nishiwaki
    Development 141 (1), 209-218 2014
    Citations: 12

  • The BED finger domain protein MIG-39 halts migration of distal tip cells in Caenorhabditis elegans
    T Kikuchi, Y Shibata, HS Kim, Y Kubota, S Yoshina, S Mitani, K Nishiwaki
    Developmental biology 397 (2), 151-161 2015
    Citations: 11

  • The Novel Secreted Factor MIG-18 Acts with MIG-17/ADAMTS to Control Cell Migration in Caenorhabditis elegans
    HS Kim, Y Kitano, M Mori, T Takano, TE Harbaugh, K Mizutani, ...
    Genetics 196 (2), 471-479 2014
    Citations: 10

  • Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans
    A Imanishi, Y Aoki, M Kakehi, S Mori, T Takano, Y Kubota, HS Kim, ...
    Plos one 15 (12), e0240571 2020
    Citations: 8

  • Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans
    Y Shibata, Y Kawakado, N Hori, K Tanaka, R Inoue, T Takano, Y Kubota, ...
    G3: Genes, Genomes, Genetics 6 (5), 1449-1457 2016
    Citations: 7

  • Endogenous chondroitin extends the lifespan and healthspan in C. elegans
    Y Shibata, Y Tanaka, H Sasakura, Y Morioka, T Sassa, S Fujii, ...
    Scientific Reports 14 (1), 4813 2024
    Citations: 3

  • Repulsive guidance molecule acts in axon branching in Caenorhabditis elegans
    K Tsutsui, HS Kim, C Yoshikata, K Kimura, Y Kubota, Y Shibata, C Tian, ...
    Scientific reports 11 (1), 1-11 2021
    Citations: 3

  • Maintenance of cell fates and regulation of the histone variant H3. 3 by TLK kinase in Caenorhabditis elegans
    Y Shibata, Y Seki, K Nishiwaki
    Biology open 8 (1), bio038448 2019
    Citations: 3

  • Maintenance of cell fates through acetylated histone and the histone variant H2A.z in C. elegans
    Y Shibata, K Nishiwaki
    Worm 3 (2), e29048 2014
    Citations: 3

  • Screening assays for targets and drugs useful in treatment and prevention of lipid metabolism disorders
    S Hekimi, Y Shibata, R Branicky
    US Patent App. 10/800,333 2004
    Citations: 2

  • Mutations in fibulin-1 and collagen IV suppress the short healthspan of mig-17/ADAMTS mutants in Caenorhabditis elegans
    Y Shibata, Y Huang, M Yoshida, K Nishiwaki
    PloS one 19 (7), e0305396 2024
    Citations: 1

  • Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration inCaenorhabditis elegans
    A Imanishi, Y Aoki, M Kakehi, S Mori, T Takano, Y Kubota, H Kim, ...
    2020
    Citations: 1

Publications

Endogenous chondroitin extends the lifespan and healthspan in C. elegans.
Scientific reports
2024-02-27 | journal-article
PMID: 38413743PMC: PMC10899230DOI: 10.1038/s41598-024-55417-7
Source:
Yukimasa Shibata
Repeat sequence corresponding to the nucleosome length at the opposite end of the pairing center on autosomes in C. elegans.
microPublication biology
2024-02-22 | journal-article
PMID: 38454953PMC: PMC10918474DOI: 10.17912/
Source:
Yukimasa Shibata
Repulsive guidance molecule acts in axon branching in Caenorhabditis elegans.
Scientific reports
2021-11-16 | journal-article
PMID: 34785759PMC: PMC8595726DOI: 10.1038/s41598-021-01853-8
Source:
Yukimasa Shibata
Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans.
PloS one
2020-12-02 | journal-article
PMID: 33264296PMC: PMC7710118DOI: 10.1371/
Source:
Yukimasa Shibata
Maintenance of cell fates and regulation of the histone variant H3.3 by TLK kinase in Caenorhabditis elegans.
Biology open
2019-01-17 | journal-article
PMID: 30635266PMC: PMC6361200DOI: 10.1242/
Source:
Yukimasa Shibata
Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans.
G3 (Bethesda, Md.)
2016-05-03 | journal-article
PMID: 26994289PMC: PMC4856095DOI: 10.1534/
Source:
Yukimasa Shibata
The BED finger domain protein MIG-39 halts migration of distal tip cells in Caenorhabditis elega

GRANT DETAILS

基底膜による老化抑制機構の研究Japan Society for the Promotion of Science (Tokyo)2022-08-31 to 2024-03-31|Grant
GRANT_NUMBER: 22K20658
URL:
Source:
Yukimasa Shibata
via
DimensionsWizard
Neuropeptide regulation of organogenesis through cell surface FoF1-ATP synthaseJapan Society for the Promotion of Science (Tokyo)2022-04-01 to 2025-03-31|Grant
GRANT_NUMBER: 22K06241
URL:
Source:
Yukimasa Shibata
via
DimensionsWizard
分化した細胞で働く運命維持機構の解明Japan Society for the Promotion of Science (Tokyo)2016-04-01 to 2019-03-31|Grant
GRANT_NUMBER: 16K07380
URL:
Source:
Yukimasa Shibata
via
DimensionsWizard
Organ size regulation - An approach by C. elegans geneticsJapan Society for the Promotion of Science (Tokyo)2015-04-01 to 2018-03-31|Grant
GRANT_NUMBER: 15H04379
URL:
Source:
Yukimasa Shibata
via
DimensionsWizard
Research of transcriptional repression mechanism by histone acetylation in the maintenance of cell fateJapan Society for the Promotion of Science (Tokyo)2011-01-01 to 2013-12-31|Grant
GRANT_NUMBER: 23770257
URL:
Source:
Yukimasa Shibata
via
DimensionsWizard
Analyses of the mechanism that maintains cell fates in an acetylated histone-dependent mannerJapan Society for the Promotion of Science (Tokyo)2009-01-01 to 2010-12-31|Grant
GRANT_