Fajar Husen

@stikesbinaciptahusada.ac.id

Medical Laboratory of Technology
College of Health Science of Bina Cipta Husada



                             

https://researchid.co/fajarhusen

Lecturer of Medical Laboratory of Technology

EDUCATION

Bachelor Degree of Biology of Jenderal Soedirman University (UNSOED)
Master of Science of Biology (Microbiology) of Jenderal Soedirman University (UNSOED)

RESEARCH INTERESTS

Microbiology, Immunology, Medical Mycology, Histology

FUTURE PROJECTS

SOYBEAN SELECTION AGAINST CERCOSPORA LEAF BLIGHT DISEASE CAUSED BY CERCOSPORA KIKUCHII BASED ON ANATOMICAL RESISTANCE

Soybean (Glycine max L. Merr.) is the third food crop commodity after rice and maize in Indonesia. This plant is also known as the most important source of vegetable protein, which is relatively inexpensive, but a decrease in soybean productivity can occur due to infection with disease-causing pathogens, one of is Cercospora kikuchii which causes Cercospora leaf blight (CLB). The research objectives were to determine the anatomical resistance and disease severity of soybean cultivars against CLB. The method was an experiment with a completely randomized design (CRD) factorial pattern; factor 1 being soybean cultivars (Dering, Slamet, Grobogan, Wilis) and factor 2, namely pathogen inoculation (0 conidiospores/mL and 105 conidiospores/mL). Anatomical method preparations using paraffin, staining with 1% safranin. Disease criteria are based on the council of scientific and industrial research (CSIR) assessment method. Data were analysis used analysis of variance (p<0.05)


Applications Invited
Anatomical resistance

Ethanol extract of the mushroom Coprinus comatus exhibits anti-diabetic and antioxidant activities in streptozotocininduced diabetic rats

To identify the benefits of ethanol extracts of the C. comatus fruit body in streptozotocin-induced hyperglycemic rats by evaluating their blood glucose, glycosylated hemoglobin (HbA1c), insulin, glucagon-like peptide-1 (GLP-1), dipeptidyl peptidase-4 (DPP-4), and glutathione (GSH) levels, with and without extract administration


Applications Invited
Antidiabetic effect

Antioxidant Activities and Properties of Coprinus comatus Mushroom Both Mycelium and Fruiting Body Extracts In Streptozotocin-Induced Hyperglycemic Rats Model

The study evaluated in vitro and in vivo treatments to evaluate antioxidant effect and activity of C. comatus. The in vivo treatment was conducted using six groups of Wistar rats (n = 24). Group 1 healthy control (HC), groups 2–6 received 45 mg/Kg BW of streptozotocin once, group 2 just streptozotocin-induced (NC), group 3 was given 45 mg/kg BW of metformin (PC), groups 4–6 were given 250 (T1), 500 (T2), and 750 mg (T3) of C. comatus extract for 14 days, and the in vitro was conducted using an antioxidant oxidant assay. Data were analyzed using analysis of variance and Duncan’s multiple-range tests


Applications Invited
Antioxidant supplement
10

Scopus Publications

151

Scholar Citations

6

Scholar h-index

2

Scholar i10-index

Scopus Publications


  • Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Nanogel in a Complete Freund's Adjuvant-Induced Rheumatoid Arthritis Rat Model: Anti-Arthritic, Anti-Inflammatory, and Antioxidative Activity
    Nuniek Ina Ratnaningtyas, Fajar Husen, and Nur Fitrianto

    Begell House
    Lingzhi or reishi mushroom, Ganoderma lucidum, is a medicinal mushroom quite widely developed as herbal medicine because it has acted as an anticancer, antitumor, antioxidant, and anti-inflammatory. The active mycochemical compounds of G. lucidum mushrooms, such as flavonoids and polysaccharides, can suppress the release of pro-inflammatory cytokines and prevent lipid peroxidation due to oxidative stress. Rheumatoid arthritis (RA) is an autoimmune disease where the exact cause is unknown, and RA prevalence continues to increase yearly. In patients with RA, joint damage and inflammation occur. This study aims to evaluate the effectiveness of G. lucidum nanogels as anti-arthritis, anti-inflammatory, and antioxidative. The research method was a true experiment using a control group and treatment group that randomly assigned, using 24 male Wistar rats (Rattus norvegicus) induced with complete Freund's adjuvant (CFA) 0.1 mL. The rats were divided into six groups; healthy control/HCt (did not receive the treatment), negative control/NCt (induced by CFA), and positive control/PCt (given 0.012 diclofenac sodium). TG1 (given 250 mg G. lucidum nanogels), TG2 (given 500 mg G. lucidum nanogels), TG3 (given 750 mg G. lucidum nanogels). IgG, eNOS, IL-1β, COX-2, NOS, TNF-α, and IL-6 parameters were measured using ELISA, and the data obtained were analyzed by one-way ANOVA using SPSS (P < 0.05). The results showed that administering G. lucidum nanogels significantly reduced IgG, NOS, TNF-α, COX-2, IL-1β, and IL-6 and increased eNOS levels. The anti-inflammatory and antioxidative activities in suppressing pro-inflammatory cytokines and increasing eNOS levels prove that the nanogel extract G. lucidum have the potential to be developed as anti-arthritis natural therapeutic.


  • Antidiabetic Effects and Enzymatic Antioxidant Activity of Chicken Drumstick Mushroom (Coprinus comatus) Extract in Diabetic Rats Model
    Nuniek Ina Ratnaningtyas, Fajar Husen, Dalia Sukmawati, Eko Setio Wibowo, Arif Rahman Hikam, and Adil Aksoy

    Journal of Pure and Applied Microbiology
    Coprinus comatus (O.F. Mull.) Pers. is a medicinal and edible mushroom containing bioactive compounds known as antidiabetic and antioxidant agents. The pancreatic β-cells were sensitive to reactive oxygen species (ROS) attacks, which can cause necrosis and disrupt insulin production. Therefore, this research aimed to evaluate the C. comatus ethyl acetate extract for antidiabetic and antioxidant to decrease fasting blood glucose, dipeptidyl peptidase-4 enzyme (DPP-4) levels, and increase glutathione peroxidase (GPx). Subsequently, 24 male Wistar rats were divided into six groups, namely 2-5 streptozotocin (STZ)-induced 45 mg/kg, 1/HC (without any treatment), 2/NC (negative control), 3/PC (administered metformin 45 mg/kg Body weight (BW), 4-6 (T1: administered 250 mg, T2: administered 500 mg, and T3: administered 750 mg/kg BW extract). The parameters were analyzed using ANOVA, followed by Duncan’s multiple range test. According to the results, the extract significantly decreased DPP-4 levels, blood glucose and increased GPx (p ≤ 0.05). The 500 mg extract effectively reduced blood glucose levels and DPP-4 enzyme as well as increased levels of GPx.

  • Anti-inflammatory and immunosuppressant activity of Coprinus comatus ethanol extract in carrageenan-induced rats of Rattus norvegicus
    Nuniek Ina Ratnaningtyas, Fajar Husen, Hernayanti Hernayanti, Nuraeni Ekowati, and Bambang Heru Budianto

    Universitas Jenderal Soedirman
    &#x0D; &#x0D; &#x0D; oprinus comatus (O.F. Mull.) is an edible mushroom that is used as an anti-inflammatory agent. Therefore, this study aims to determine the effect of inflammation treatment on symptoms alleviating, function maintenance, and inhibiting the process of tissue damage due to an increase in free radicals using drug formulations with high antioxidant compounds. This is a true experiment conducted using a Completely Randomized Design (CRD) with a post-test and a control group. The rats were divided into 6 categories, which include 1 healthy and 5 groups induced with 1% carrageenan. Out of the treatment groups, 3 were treated with ethanol extract of C. comatus fruiting body at doses of 250 (T1), 500 (T2), and 750 mg/kg BW (T3), 1 received diclofenac sodium (PC) and the other as a negative control (NC), were given extract for 14 days and induced with 0.5 mL carrageenan in paw of rats at day 15. The qualitative identification showed the extracts contains flavonoid, polyphenol, alkaloid, triterpenoid, steroids and saponins, and GC-MS analysis showed 10 putative metabolites compound. T2 group significantly decreased the levels of IL-1β (70.63%), IgE (59.04%), total leukocyte count (31.24%), plantar thickness (12.5%), edema volume (33.3%), and increased endothelial NO levels (48.2%).&#x0D; &#x0D; &#x0D;

  • Soybean Selection Against Cercospora Leaf Blight Disease Caused By Cercospora kikuchii Based on Anatomical Resistance
    Fajar Husen, Nuniek Ina Ratnaningtyas, Siti Samiyarsih, Juni Safitri Muljowati, and Nur Fitrianto

    Universitas Negeri Semarang
    Soybean (Glycine max L. Merr.) is the third food crop commodity after rice and maize in Indonesia. This plant is also known as the most important source of vegetable protein, which is relatively inexpensive, but a decrease in soybean productivity can occur due to infection with disease-causing pathogens, one of is Cercospora kikuchii which causes Cercospora leaf blight (CLB). The research objectives were to determine the anatomical resistance and disease severity of soybean cultivars against CLB. The method was an experiment with a completely randomized design (CRD) factorial pattern; factor 1 being soybean cultivars (Dering, Slamet, Grobogan, Wilis) and factor 2, namely pathogen inoculation (0 conidiospores/mL and 105 conidiospores/mL). Anatomical method preparations using paraffin, staining with 1% safranin. Disease criteria are based on the council of scientific and industrial research (CSIR) assessment method. Data were analysis used analysis of variance (p0.05) and the least significance difference (LSD). The results showed that Dering and Slamet cultivars had the largest cuticle, epidermis, and palisade ratios and the smallest stomata length and width with the largest number of stomata and trichomes compared to Grobogan and Wilis. The disease severity (DS) of the cultivars Dering 14.6%, Slamet 24.64%, Grobogan 24.80% (classified as a resistant with low infection), while Wilis cultivar was 31.08% as a moderately susceptible cultivar with moderate infection. The novelty of soybean cultivar selection against CLB is important and its effectiveness for increasing soybean productivity. Dering, Slamet and Grobogan are likely to be further developed with their resistance to CLB disease.

  • Antioxidant Activities and Properties of Coprinus comatus Mushroom Both Mycelium and Fruiting Body Extracts In Streptozotocin-Induced Hyperglycemic Rats Model
    Nuniek Ina Ratnaningtyas, Hernayanti Hernayanti, Nuraeni Ekowati, Fajar Husen, Isnaini Maulida, Riama Kustianingrum, and Vika Vidiyanti

    Universitas Negeri Semarang
    Coprinus comatus, well-known as Shaggy Ink Cap mushroom, is potential herbal medicine. Synthetic medicines sometimes cause side effects; therefore, it is necessary to innovate with herbal medications with minimal side effects. The study evaluated in vitro and in vivo treatments to evaluate the antioxidant effect and activity of C. comatus. The in vivo treatment was conducted using six groups of Wistar rats (n = 24). Group 1 healthy control (HC), groups 2–6 received 45 mg/Kg BW of streptozotocin once, group 2 just streptozotocin-induced (NC), group 3 was given 45 mg/kg BW of metformin (PC), groups 4–6 were given 250 (T1), 500 (T2), and 750 mg (T3) of C. comatus extract for 14 days, and the in vitro was conducted using an antioxidant oxidant assay. Data were analyzed using analysis of variance and Duncan's multiple range tests. Based on qualitative analysis, C. comatus mycelium extract contained polyphenol, flavonoids, terpenoids, and fruiting body extract had flavonoids, alkaloids, and saponins. The in vitro analysis showed that the mycelium extract had an antioxidant activity by inhibiting free radicals up to 58.51% with an IC50 value of 72.77 mg/L. The in vivo treatment using C. comatus fruiting body extract showed that it could increase the endogenous antioxidant levels of GPx, SOD, catalase and reduce MDA levels (p 0.05). The most effective dose of C. comatus extract is 500 mg. This research has shown the potential of mycelium and C. comatus fruitbody extract as an antioxidant supplement in a diabetic rat model.

  • Ethanol extract of the mushroom Coprinus comatus exhibits antidiabetic and antioxidant activities in streptozotocin-induced diabetic rats
    N. I. Ratnaningtyas, Hernayanti Hernayanti, Nuraeni Ekowati and F. Husen


    Abstract Context Edible mushrooms have a long history of use in traditional Chinese or Japanese medicine. Coprinus comatus (O.F. Müll.) Pers. (Agaricaceae) contains antioxidant and antidiabetic agents. Objective To identify the benefits of ethanol extracts of the C. comatus fruit body in streptozotocin-induced hyperglycaemic rats by evaluating their blood glucose, glycosylated haemoglobin (HbA1c), insulin, glucagon-like peptide-1 (GLP-1), dipeptidyl peptidase-4 (DPP-4), and glutathione (GSH) levels, with and without extract administration. Materials and methods Wistar rats were either left untreated or were administered 45 mg/kg body weight (BW) streptozotocin; 45 mg/kg BW metformin; or 250, 500, or 750 mg/kg BW extract for 14 days. The blood glucose, GLP-1, DPP-4, GSH, insulin, and HbA1c levels were determined. Data were analysed using analysis of variance and Duncan’s multiple range tests. Results Preliminary data showed that administration of C. comatus ethanol extract dose of 250, 500, and 750 mg orally has no toxicity effects after 24 h administration. The ethanolic extract of fruiting body of C. comatus considerably reduced the rat’s fasting blood glucose levels 26.69%, and DPP-4 6.97% at dose of 750 mg. The extract reduced HbA1c 4–4.30%, increased GLP-1 71.09%, GSH 11.19% at dose of 500 mg, and increased insulin levels 13.83%. Extracts contain bioactive compounds such as flavonoid, alkaloid, terpenoids, vitamins C and E, rutin, and saponin. Conclusions The C. comatus extract can be used as herbal medicine that reduces diabetic symptoms. Further investigation on C. comatus extracts should be conducted with gas chromatography-mass spectrometry to characterise the bioactive compounds.

  • Nephroprotective and antioxidant effects of ethanol extract of Coprinus comatus mushroom fruit-bodies on streptozotocin-induced diabetic rat models
    N. I. Ratnaningtyas, Hernayanti, N. Ekowati and F. Husen


    Diabetes mellitus (DM) is a metabolic disease with an increasing prevalence. An increase in free radicals and AGEs can cause glomerular cell damage which can lead to inflammation and DM nephropathy. WHO has recommended DM treatment by using herbal medicines that have minimal side effects and have a lot of biological activity to prevent complications. Coprinus comatus (O.F. Mull.) is known as immunomodulatory, anti-inflammatory and antidiabetic agent. The research used C. comatus cultivated in Cianjur. The basidiome of this mushroom has slightly oval and small with height of 8-12 cm and thickness of 2-3 cm. The research included six groups of male Wistar rats: Group 1 received no treatment, Groups 2–6 were administered 45 mg/kg BW streptozotocin once, Group 3 was administered 45 mg/kg BW metformin, Groups 4, 5, and 6 were administered 250, 500, and 750 mg/kg BW of C. comatus fruit body ethanol extract respectively for 14 days. The superoxide dismutase (SOD), malondialdehyde (MDA), hepcidin and β2 microglobulin (B2M) levels were evaluated. Data were analyzed using analysis of variance and Duncan’s multiple-range tests. The results showed that dose of 500 mg was effective in increasing SOD and decreasing hepcidin, B2M and MDA levels.

  • Antidiabetic effects and antioxidant properties of the saggy ink cap medicinal mushroom, coprinus comatus (Agaricomycetes), in streptozotocin-induced hyperglycemic rats
    Fajar Husen, Hernayanti Hernayanti, Nuraeni Ekowati, Dalia Sukmawati, and Nuniek Ina Ratnaningtyas

    Begell House
    Coprinus comatus is known for its antihyperglycemic benefits. This study aimed to identify the effect of bioactive compounds of C. comatus extract as an antidiabetic agent linked to glucagon-like peptide 1 (GLP-1) and antioxidant properties in increasing glutathione (GSH) levels. This study used six groups of Wistar rats (n = 24). Group 1 comprised the healthy control. Groups 2-6 received 45 mg of streptozotocin/kg body weight (BW) once. Group 3 was also given 45 mg of metformin/kg BW, whereas groups 4-6 were also given 250, 500, and 750 mg of C. comatus ethyl acetate extract/kg BW for 14 days. Antidiabetic effects of alkaloids and saponin were seen in blood glucose and glycated hemoglobin (HbA1c) degradation, increased insulin, and increased inhibition of GLP-1 through dipeptidyl peptidase-4 activity. Flavonoid antioxidants, ascorbic acid (vitamin C), and α-tocopherol (vitamin E) are useful in protecting pancreatic в cells from free radicals. Data were analyzed using analysis of variance and Duncan's multiple range test. C. comatus ethyl acetate extract at doses of 250, 500, and 750 mg/kg BW worked as an antidiabetic and antioxidant agent that contained flavonoids (16.4 mg/L), alkaloids (2.97 mg/L), saponin, rutin (351.13 ppm), vitamin C (132.342 mg/L), and vitamin E (102.320 g/L). The 250-mg dose was effective in increasing insulin (8.11 mlU/mL) and reducing blood glucose (23.92%) and HbA1c (3.775%), whereas the 500-mg dose was effective in increasing levels of GLP-1 (1056.923 ng/L) and GSH (4.62 μmol/L).

RECENT SCHOLAR PUBLICATIONS

  • Profil Sedimen Urin Pasien Suspek Infeksi Saluran Kemih Di Puskesmas Purwokerto Selatan
    NAH Khasanah, F Husen, NI Yuniati
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 20 (2), 51-59 2024

  • Identifikasi Jamur Non-Dermatofita Penyebab Onikomikosis Kuku (Tinea unguium) Pada Petani Padi
    F Husen, NAH Khasanah, NI Ratnaningtyas
    Jurnal Media Analis Kesehatan 15 (1), 35-45 2024

  • AKTIVITAS ANTIBAKTERI EKSTRAK DAUN KELOR (Moringa oleifera Lamk.) TERHADAP BAKTERI Escherichia coli PENYEBAB PENYAKIT GANGGUAN PENCERNAAN SECARA IN VITRO
    F Husen, NI Ratnaningtyas
    Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ 11 (2), 77-83 2024

  • Bunga Rampai Imunologi Dasar
    AAAE Cahyani, AF Wijaya, YF Adjungbulu, Sugiah, F Husen, KA Wardani, ...
    PT. Media Pustaka Indo 1, 206 2024

  • Effect of gamma irradiation on the microbiological properties, phenolic content, and antioxidant activity of mangosteen (Garcinia mangostana L) flesh during storage
    N Fitrianto, S Samiyarsih, F Husen, A Frediansyah, GA Hidayat
    AIP Conference Proceedings 2967 (1) 2024

  • BIOACTIVE COMPOUND ANALYSIS JAMUR Coprinus comatus SECARA KUALITATIF DAN KUANTITATIF MENGGUNAKAN GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS)
    NI Ratnaningtyas, F Husen
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 20 (1), 66-76 2024

  • Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Nanogel in a Complete Freund's Adjuvant-Induced Rheumatoid Arthritis Rat Model
    NI Ratnaningtyas, F Husen, N Fitrianto
    International Journal of Medicinal Mushrooms 26 (8) 2024

  • PENGENALAN INSTRUMENTASI LABORATORIUM UNTUK MAHASISWA
    Y Pradika, IGAAS Dewi, A Febriyossa, T Febriyanto, SP Djasfar, ...
    Magelang: PT. ADIKARYA PRATAMA GLOBALINDO 1, 203 2023

  • Tea Fungus Beverages from Torch Ginger (Etlingera elatior): Total microbial, Physicochemical, and Antioxidant Activity
    N Fitrianto, F Husen, S Samiyarsih, NI Ratnaningtyas, LS Palindung, ...
    Biosaintifika: Journal of Biology & Biology Education 15 (3), 351-361 2023

  • HUBUNGAN KADAR ASAM URAT DAN GLUKOSA DARAH PADA WANITA USIA DEWASA-TUA DI DESA MANDIRAJA WETAN
    F Husen, NI Ratnaningtyas
    Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ 10 (3), 177-185 2023

  • PENGUJIAN INFUSA REBUSAN BUNGA TELANG (CLITORIA TERNATEA) SEBAGAI PEWARNA ALAMI SEDIAAN APUS DARAH TEPI (SADT)
    F Husen, NAH Khasanah
    EduMatSains: Jurnal Pendidikan, Matematika Dan Sains 8 (1), 1-7 2023

  • POTENSI AKTIVITAS ANTIBAKTERI EKSTRAK Moringa oleifera (Lamk.) TERHADAP BAKTERI ESCHERICHIA COLI SECARA IN SILICO DAN IN VITRO
    D Islamiyati, F Husen, NI Ratnaningtyas
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 19 (2), 80-90 2023

  • KUALITAS RENDAMAN SIMPLISIA RIMPANG KUNYIT (Curcuma longa) SEBAGAI PEWARNA ALTERNATIF TELUR Ascaris lumbricoides
    NAH Khasanah, F Husen, NI Yuniati, UF Rudatiningtyas
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 19 (2), 54-62 2023

  • Dasar-Dasar Biomedik
    NF Fahmi, RT Utami, NI Yuniati, NR Shafriani, NAH Khasanah, ...
    Penerbit PT. Son Pedia Publishing 1, 1-146 2023

  • Eksplorasi, Identifikasi, Dan Karakterisasi Senyawa Fitokimia Coprinus comatus Dan Ganoderma lucidum Menggunakan GC-MS (Gas Chromatography-Mass Spectrometry)
    NI Ratnaningtyas, F Husen, N Ekowati, ES Purwati
    Prosiding Seminar Nasional Pengembangan Sumber Daya Perdesaan dan Kearifan 2023

  • Prosiding Seminar Nasional Biologi Tropika 2022: AKTIVITAS ANTIOKSIDAN EKSTRAK BETA GLUCAN KHAMIR FISI (Schizosaccharomyces pombe) DENGAN METODE DPPH
    N Fitrianto, F Husen, GA Hidayat
    Penerbit: Uwais Inspirasi Indonesia 1, 114-116 2023

  • AKTIVITAS ANTIOKSIDAN EKSTRAK BETA GLUCAN KHAMIR FISI (Schizosaccharomyces pombe) DENGAN METODE DPPH
    N Fitrianto, F Husen, GA Hidayat
    Prosiding Seminar Nasional Biologi Tropika 2022: Masa Depan Biodiversitas 2023

  • Buku Ajar Imunologi
    IA Faizal, F Husen, M Taufiqurrahman, Witriyani, T Supriatin, R Ambarwati, ...
    CV. Science Techno Direct 1, 1-233 2023

  • Jamur Non-Dermatofita Pada Kuku Jari Tangan (Finger Nails) Penyebab Onikomikosis
    F Husen, NI Ratnaningtyas, NAH Khasanah, NI Yuniati, D Islamiyati
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 19 (1), 77-87 2023

  • Kondisi Santriwati Saat Menstruasi Di Pondok Pesantren Miftahul Huda Dan Korelasinya Dengan Pengetahuan, Sikap Dan Praktik Personal Hygiene
    UF Rudatiningtyas, F Husen, NAH Khasanah, T Fitriyani
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 19 (1), 25-36 2023

MOST CITED SCHOLAR PUBLICATIONS

  • Ethanol extract of the mushroom Coprinus comatus exhibits antidiabetic and antioxidant activities in streptozotocin-induced diabetic rats
    NI Ratnaningtyas, H Hernayanti, N Ekowati, F Husen
    Pharmaceutical Biology 60 (1), 1126-1136 2022
    Citations: 33

  • Antidiabetic Effects and Antioxidant Properties of the Saggy Ink Cap Medicinal Mushroom, Coprinus comatus (Agaricomycetes), in Streptozotocin-Induced Hyperglycemic Rats
    F Husen, H Hernayanti, N Ekowati, D Sukmawati, NI Ratnaningtyas
    International Journal of Medicinal Mushrooms 23 (10), 9-21 2021
    Citations: 27

  • Karakteristik, Profil Dan Diganosa Pasien Hipertensi Rawat Inap Di Rsu Aghisna Sidareja Kabupaten Cilacap
    F Husen, R Basuki
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 18 (2), 59-73 2022
    Citations: 8

  • Peningkatan Kadar Kolesterol dan Usia Pada Ibu Rumah Tangga
    F Husen, NI Ratnaningtyas, NAH Khasanah, NI Yuniati
    Jurnal Ilmiah Kesehatan Sandi Husada 11, 351-59 2022
    Citations: 7

  • Inhibitory Test of Gentamicin Antibiotics Against Escherichia coli and Staphylococcus aureus Bacteria Using Disc Method
    F Husen, NI Ratnaningtyas
    Biotropika: Journal of Tropical Biology 10 (2), 126-131 2022
    Citations: 7

  • Antidiabetic Effects and Enzymatic Antioxidant Activity of Chicken Drumstick Mushroom (Coprinus comatus) Extract in Diabetic Rats Model
    NI Ratnaningtyas, F Husen, D Sukmawati, ES Wibowo, AR Hikam, ...
    Journal of Pure and Applied Microbiology 16 (4), 1-11 2022
    Citations: 6

  • Antioxidant Activities and Properties of Coprinus comatus Mushroom Both Mycelium and Fruiting Body Extracts In Streptozotocin-Induced Hyperglycemic Rats Model
    NI Ratnaningtyas, H Hernayanti, N Ekowati, F Husen, I Maulida, ...
    Biosaintifika: Journal of Biology & Biology Education 14 (1), 9-21 2022
    Citations: 6

  • Soybean selection against Cercospora leaf blight disease caused by Cercospora kikuchii based on anatomical resistance
    F Husen, NI Ratnaningtyas, S Samiyarsih, JS Muljowati, N Fitrianto
    Biosaintifika: Journal of Biology & Biology Education 14 (1), 90-102 2022
    Citations: 6

  • Karakteristik dan gambaran diagnosa komplikasi pasien diabetes di rumah sakit umum aghisna sidareja
    R Basuki, F Husen
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 18 (2), 1-15 2022
    Citations: 5

  • Nephroprotective and antioxidant effects of ethanol extract of Coprinus comatus mushroom fruit-bodies on streptozotocin-induced diabetic rat models
    NI Ratnaningtyas, N Ekowati, F Husen
    IOP Conference Series: Earth and Environmental Science 948 (1), 012078 2021
    Citations: 5

  • Penerapan aplikasi sayang ke buah hati (SEHATI) terhadap pengetahuan ibu serta dampak pada keterampilan anak tentang cara menyikat gigi
    S Safitri, H Melinda, BS Noegroho, F Husein, D Marhaeni, JTB Djais
    Global Medical & Health Communication (GMHC) 6 (1), 68-73 2018
    Citations: 5

  • Pewarnaan Sediaan Apusan Darah Tepi (SADT) Menggunakan Infusa Bunga Telang (Clitorea ternatea)
    NAH Khasanah, F Husen, NI Yuniati
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 19 (1), 67-76 2023
    Citations: 4

  • Anti-inflammatory and immunosuppressant activity of Coprinus comatus ethanol extract in carrageenan-induced rats (Rattus norvegicus)
    NI Ratnaningtyas, F Husen, H Hernayanti, N Ekowati, BH Budianto
    Molekul 17 (3), 335-345 2022
    Citations: 4

  • HUBUNGAN DAN PROFIL TEKANAN DARAH DENGAN PENINGKATAN KADAR GLUKOSA DARAH PEDAGANG DI DESA MANDIRAJA WETAN
    F Husen, NI Ratnaningtyas
    Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ 9 (3), 209-306 2022
    Citations: 4

  • Sosialisasi Dan Monitoring Kebersihan Tandon Air Di Desa Mandiraja Wetan Sebagai Upaya Peningkatkan Status Kesehatan
    F Husen, NI Ratnaningtyas, NI Yuniati, NAH Khasanah, ...
    Jurnal Pengabdian Masyarakat Indonesia 2 (4), 459-464 2022
    Citations: 3

  • Eksplorasi, Identifikasi, Dan Karakterisasi Senyawa Fitokimia Coprinus comatus Dan Ganoderma lucidum Menggunakan GC-MS (Gas Chromatography-Mass Spectrometry)
    NI Ratnaningtyas, F Husen, N Ekowati, ES Purwati
    Prosiding Seminar Nasional Pengembangan Sumber Daya Perdesaan dan Kearifan 2023
    Citations: 2

  • Jamur Non-Dermatofita Pada Kuku Jari Tangan (Finger Nails) Penyebab Onikomikosis
    F Husen, NI Ratnaningtyas, NAH Khasanah, NI Yuniati, D Islamiyati
    Jurnal Bina Cipta Husada: Jurnal Kesehatan Dan Science 19 (1), 77-87 2023
    Citations: 2

  • BUKU AJAR IMUNOLOGI
    D Luthfianto, C Indriputri, ST AK, M Imun, DRPS Kp, IA Faizal, ST AK, ...
    2023
    Citations: 2

  • Increased Cholesterol Levels and Age in Housewives
    F Husen, NI Ratnaningtyas, NAH Khasanah, NI Yuniati
    Jurnal Ilmiah Kesehatan Sandi Husada 11 (2), 343-351 2022
    Citations: 2

  • Analisis Faktor Risiko Personal Hygiene terhadap Pediculosis capitis pada Santriwati Ponpes Miftahul Huda: Personal Hygiene Risk Factor Analysis of Pediculosis capitis in
    NAHK Khasanah, NI Yuniati, F Husen, UF Rudatiningtyas
    Journal of Holistics and Health Sciences (JHHS) 4 (2), 282-291 2022
    Citations: 2

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

Effervescent of Mushroom Extracts