Glauco Botelho dos Santos

EDUCATION

Graduação em Odontologia pela Faculdade de Odontologia de Nova Friburgo (1997), é especialista em Dentística pela USP (1999) e Implantodontia (2015), mestre em Odontologia (Materiais Dentários) pela Universidade de São Paulo (2003) e doutor em Odontologia (Dentística) pela UERJ (2008)

RESEARCH INTERESTS

COMPÓSITOS, CERÂMICAS, FOTOATIVAÇÃO

FUTURE PROJECTS

Scopus Publications

Impact of bisphosphonate therapy on dental implant outcomes: An overview of systematic review evidence
V. Mendes, G.O. dos Santos, M.D. Calasans-Maia, J.M. Granjeiro, and V. Moraschini
International Journal of Oral and Maxillofacial Surgery, ISSN: 09015027, eISSN: 13990020, Pages: 373-381, Published: March 2019 Elsevier BV
The purpose of this overview was to assess the methods, quality, and outcomes of systematic reviews conducted to evaluate the impact of bisphosphonates on dental implants and the risk of developing bisphosphonate-related osteonecrosis of the jaw after dental implant surgery. An electronic search without date or language restriction was performed in the PubMed/MEDLINE, Cochrane CENTRAL, Web of Science, and LILACS databases (to January 2018). Eligibility criteria included systematic reviews that evaluated the impact of bisphosphonates on implant outcomes. The quality assessment of the included reviews was done using AMSTAR 2 guidelines. The protocol of this overview was registered in PROSPERO (CRD42018089617). The search and selection process yielded seven reviews, published between 2009 and 2017. None of the systematic reviews included in this study obtained the maximum score in the quality assessment. The scientific evidence available demonstrates that patients with a history of bisphosphonate use do not present a higher risk of dental implant failure or marginal bone loss compared to patients who have not used bisphosphonates. The literature also suggests that patients who undergo surgical trauma during the installation of dental implants may be more susceptible to bisphosphonate-related osteonecrosis of the jaw.


Effect of different times of nonthermal argon plasma treatment on the microtensile bond strength of self-adhesive resin cement to yttria-stabilized tetragonal zirconia polycrystal ceramic
Alexandre Barboza Elias, Renata Antoun Simão, Maíra Prado, Paulo Francisco Cesar, Glauco Botelho dos Santos, and Eduardo Moreira da Silva
Journal of Prosthetic Dentistry, ISSN: 00223913, Volume: 121, Pages: 485-491, Published: March 2019 Elsevier BV
Statement of problem. Nonthermal argon plasma may increase the surface energy of yttria‐stabilized tetragonal zirconia polycrystal (Y‐TZP) dental ceramics. However, studies that evaluated the effect of increased plasma treatment times on the bond strength of resin cements to Y‐TZP ceramics are lacking. Purpose. The purpose of this in vitro study was to evaluate the effect of different nonthermal argon plasma (NTAP) treatment times on the surface energy and bond strength of a self‐adhesive resin cement to Y‐TZP ceramic. Material and methods. Forty‐eighty Y‐TZP plates were divided into 2 groups (n=24): as‐sintered (AS) and airborne‐particle abrasion (APA) with 50‐&mgr;m Al2O3, which were subdivided into 4 groups (n=6) according to the time of NTAP treatment: 0, 20, 60, and 120 seconds. The surface energy was evaluated with a goniometer. Forty Y‐TZP blocks submitted to the same surface treatments (8 groups; n=5) were cemented to composite resin blocks, using a self‐adhesive resin cement. After storage in distilled water at 37°C for 24 hours, the Y‐TZP‐composite resin blocks were cut into beams and submitted to a microtensile bond strength (&mgr;TBS) test. Data were analyzed using 2‐way ANOVA and the Tukey honestly significant differences test (&agr;=.05). Results. Treatment with NTAP increased the surface energy for AS and APA groups (P<.05). For both groups, the &mgr;TBS was as follows: 0 seconds < 20 seconds < 60 seconds = 120 seconds (P<.05). Only after 120 seconds of NTAP treatment was the &mgr;TBS of APA higher than that of AS (P<.05). Conclusions. Treatment with NTAP improved the surface energy and increased the &mgr;TBS of self‐adhesive resin cement to Y‐TZP ceramic, with higher times of plasma treatment resulting in higher bond strength.


Erratum to “Interrelation of periodontal parameters between asthmatics and nonasthmatics subjects: A systematic review and meta-analysis” [J. Dent. 69 (2018) 32–40] (Journal of Dentistry (2018) 69 (32–40), (S0300571217302932) (10.1016/j.jdent.2017.11.011))
Vivian Mendes, Gustavo Oliveira dos Santos, and Vittorio Moraschini
Journal of Dentistry, ISSN: 03005712, Pages: 112, Published: October 2018 Elsevier BV



Effectiveness for dentin hypersensitivity treatment of non-carious cervical lesions: a meta-analysis
Vittorio Moraschini, Larissa Salina da Costa, and Gustavo Oliveira dos Santos
Clinical Oral Investigations, ISSN: 14326981, eISSN: 14363771, Pages: 617-631, Published: 1 March 2018 Springer Science and Business Media LLC
ObjectiveThe aim of this review is to conduct a systematic review and meta-analysis comparing the effectiveness of in-home or in-office treatments for dentin hypersensitivity.Materials and methodsAn electronic search without restriction on dates or languages was performed in four electronic databases until March 2017. In addition, hand-searches in regular journals and in the gray literature were also conducted. To develop the search strategy, clinical questions were formulated using the PICOS method. Eligibility criteria included randomized clinical trials (RCTs) that compared the effectiveness of different agents for the treatment of dentin hypersensitivity through chemical occlusion, physical occlusion, nerve desensitization, or photobiomodulation (low-level light therapy). This systematic review was registered in PROSPERO under number CRD42016039394.ResultsTwenty-five RCTs (16 parallel; 9 split-mouth), published from 1992 to 2016, were included. The results of the meta-analysis showed that in-office subgroups treated with chemical or physical occlusion of dentin tubules and nerve desensitization had a statistically significant difference from placebo, with P < 0.00001, P < 0.00001, and P = 0.02, respectively. For in-home treatments, the results of the meta-analysis showed that only those subgroups treated with chemical occlusion of dentin tubules and nerve desensitization exhibited a statistically significant difference from placebo, with P < 0.00001 and P = 0.03, respectively.ConclusionsThe results of pairwise meta-analysis suggest that among in-office treatments, dentinal tubule occlusion (whether chemical or physical) and nerve desensitization provide the best outcomes for treatment of dentin hypersensitivity. For in-home treatments, only chemical occlusion of dentin tubules and nerve desensitization showed a greater treatment efficacy than placebo and the difference was statistically significant.


Interrelation of periodontal parameters between asthmatics and nonasthmatics subjects: a systematic review and meta-analysis
Vivian Mendes, Gustavo Oliveira dos Santos, and Vittorio Moraschini
Journal of Dentistry, ISSN: 03005712, Pages: 32-40, Published: February 2018 Elsevier BV
BACKGROUND The aim of this systematic review (SR) is to evaluate the association between asthma and periodontal parameters. METHODS An electronic search without date or language restrictions ​​was carried out in MEDLINE, Cochrane, Web of Science, and LILACS until May 2017. In addition, manual search and in the grey literature were also conducted. The search process, data analysis, and quality assessment were performed by two independent reviewing authors. Eligibility criteria included prospective and retrospective cohort studies, case-controls, and randomized clinical trials. For the meta-analysis, the inverse variance method was used in fixed or random effect models, which were chosen according to heterogeneity. The estimates of the intervention effects were expressed as the mean differences. RESULTS The search and selection process yielded 21 studies, published between 1979 and 2017. The meta-analysis showed a statistically significant difference for the parameters of gingival bleeding, plaque index, and gingival index for asthmatic participants with P<0.0001, P<0.0001, and P=0.0005, respectively. CONCLUSIONS The data from this SR suggest that asthmatic patients may be more susceptible to negative periodontal changes, althought further high-quality research wuold be welcome.


Noninvasive approach to esthetic rehabilitation of conoid anterior teeth
General Dentistry, ISSN: 03636771, Pages: e12-e16, Published: September-October 2017



Effect of intra-oral aging on t→m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics
Luciana Meireles Miragaya, Renato Bastos Guimarães, Rodrigo Othávio de Assunção e Souza, Glauco dos Santos Botelho, José Guilherme Antunes Guimarães, and Eduardo Moreira da Silva
Journal of the Mechanical Behavior of Biomedical Materials, ISSN: 17516161, eISSN: 18780180, Pages: 14-21, Published: 1 August 2017 Elsevier BV
The aim of the present study was to evaluate the influence of intra-oral aging on the tetragonal-to-monoclinic (t→m) phase transformation of two Y-TZP dental ceramics - Lava Frame (Frame) and Lava Plus (Plus) - and determine the impact of this response on their microstructures and mechanical properties: flexural strength, Young's modulus, microhardness and fracture toughness. Standardized ceramic specimens were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM) and atomic force microscopy (AFM). After the baseline analysis, the specimens were attached to personalized intra-oral resin appliances and exposed to the oral cavity of 20 subjects for 60 days and then analyzed again. Specimens produced for mechanical properties evaluation were also analyzed before and after the 60-day intra-oral aging. The data were analyzed using two-way ANOVA and Tukey HSD's post hoc test (α=0.05). Weibull analysis was used to evaluate the strength reliability. Both Y-TZP ceramics suffered t→m phase transformation after 60-day intra-oral aging (Plus=4.7%/Frame=7.7%). SEM and AFM analyses showed dislodgement of ZrO2 grains and a significant increase in roughness after intra-oral aging for both ceramics. Both Y-TZP ceramics suffered a decrease on flexural strength, Young's modulus and fracture toughness after intra-oral aging (p<0.05). Only Plus presented a decrease of microhardness after intra-oral aging (p<0.05). Intra-oral aging for 60 days produced t→m phase transformation, changed the microstructure and decreased the mechanical properties of two Y-TZP dental ceramics.


ZnCl<inf>2</inf> Incorporated into Experimental Adhesives: Selected Physicochemical Properties and Resin-Dentin Bonding Stability
Giselle Soares Almeida, Eduardo Moreira da Silva, José Guilherme Antunes Guimarães, Rayssa Nogueira Lamego da Silva, Glauco Botelho dos Santos, and Laiza Tatiana Poskus
BioMed Research International, ISSN: 23146133, eISSN: 23146141, Volume: 2017, Published: 2017 Hindawi Limited
The aim of this study was to evaluate the degree of conversion (DC%), water sorption (WS), solubility (SO), and resin-dentin bonding stability of experimental adhesive systems containing ZnCl2. Different concentrations (wt.%) of ZnCl2 were added to a model etch-and-rinse adhesive system consisting of BISGMA, HEMA, UDMA, GDMA, water, and ethanol: Zn0 (0%-control group); Zn2 (2%); Zn3.5 (3.5%); and Zn5 (5%). Adper Single Bond 2 (SB) was used as commercial reference. The samples were light cured for 20s using a quartz-tungsten-halogen unit (650 mW/cm2). DC% (n=5) was measured using FT-IR spectroscopy, and WS and SO (n=5) were calculated based on ISO4049. Microtensile bond strength (μTBS) and nanoleakage (NL) were measured after 24 h and 12 months of water storage (n=10). Data were analyzed using ANOVA and Tukey’s HSD test (5%). Zn5 presented the lowest DC% and the highest WS and SO (p&lt;0.05). Zn0 and Zn2 presented statistically similar DC%, WS, SO, and immediate μTBS. All adhesives containing ZnCl2 maintained a μTBS stability after 12 months, but only Zn2 and Zn3.5 did not suffer an increase in NL. SB presented the highest immediate μTBS but the greatest reduction after 12 months (p&lt;0.05). The addition of 2 wt.% of ZnCl2 in adhesive formulations seems to be a promising way to improve the resin-dentin bonding stability. Higher concentrations than 2 wt.% could impair some physicochemical properties.


Characterization of conventional and high-translucency Y-TZP dental ceramics submitted to air abrasion
Bhenya Ottoni Tostes, Renato Bastos Guimarães, Jaime Dutra Noronha-Filho, Glauco dos Santos Botelho, José Guilherme Antunes Guimarães, and Eduardo Moreira da Silva
Brazilian Dental Journal, ISSN: 01036440, eISSN: 18064760, Pages: 97-104, Published: 2017 FapUNIFESP (SciELO)
Abstract This study evaluated the effect of air-abrasion on t®m phase transformation, roughness, topography and the elemental composition of three Y-TZP (Yttria-stabilized tetragonal zirconia polycrystal) dental ceramics: two conventional (Lava Frame and IPS ZirCad) and one with high-translucency (Lava Plus). Plates obtained from sintered blocks of each ceramic were divided into four groups: AS (as-sintered); 30 (air-abrasion with 30 mm Si-coated Al2O3 particles); 50 (air-abrasion with 50 mm Al2O3 particles) and 150 (air-abrasion with 150 mm Al2O3 particles). After the treatments, the plates were submitted to X-ray diffractometry; 3-D profilometry and SEM/EDS. The AS surfaces were composed of Zr and t phases. All treatments produced t®m phase transformation in the ceramics. The diameter of air-abrasion particles influenced the roughness (150&gt;50&gt;30&gt;AS) and the topography. SEM analysis showed that the three treatments produced groove-shaped microretentions on the ceramic surfaces, which increased with the diameter of air-abrasion particles. EDS showed a decrease in Zr content along with the emergence of O and Al elements after air-abrasion. Presence of Si was also detected on the plates air-abraded with 30 mm Si-coated Al2O3 particles. It was concluded that irrespective of the type and diameter of the particles, air-abrasion produced t®m phase transformation, increased the roughness and changed the elemental composition of the three Y-TZP dental ceramics. Lava Plus also behaved similarly to the conventional Y-TZP ceramics, indicating that this high translucency ceramic could be more suitable to build monolithic ceramic restorations in the aesthetic restorative dentistry field.


Resin-dentin bond stability of experimental 4-META-based etch-and-rinse adhesives solvated by ethanol or acetone
C. Amaral, Alice Marques Diniz, Eugênio Braz Rodrigues Arantes, Glauco Botelho dos SANTOS, J. D. Noronha-Filho and E. D. da Silva
Journal of Adhesive Dentistry, ISSN: 14615185, eISSN: 17579988, Pages: 513-520, Published: 2016
PURPOSE To investigate the influence of 4-META concentration and type of solvent on the degree of conversion (DC%) and resin-dentin bond stability of experimental etch-and-rinse adhesives. MATERIALS AND METHODS Four different concentrations of 4-META (12 wt%, 20 wt%, 30 wt%, 40 wt%) were added to a model adhesive system consisting of TEG-DMA (25 wt%), UDMA (20 wt%), HEMA (30 wt%), water (4 wt%), camphorquinone (0.5 wt%), and tertiary amine (0.5 wt%) dissolved in 20% acetone (A12, A20, A30 and A40) or 20% ethanol (E12, E20, E30 and E40). DC% was evaluated by FT-IR spectroscopy. Human molars were wet ground until the occlusal dentin was exposed, the adhesive systems were applied after 37% phosphoric acid etching, and resin composite buildups were incrementally constructed. After storage in distilled water at 37°C for 24 h, the teeth were cut into resin-dentin beams (cross-sectional area 1 mm2). Microtensile bond strength (μTBS) was evaluated after 24 h, 6 months, and 1 year of water storage at 37°C. The failure mode was categorized as adhesive, mixed, or cohesive. Data were analyzed using ANOVA and Tukey's HSD test (α = 0.05). RESULTS A12 presented the lowest DC% (p < 0.05). All the other adhesive systems showed statistically similar DC% (p > 0.05). All adhesive systems maintained resin-dentin bond stability after 6 months of water storage, while only A40 and E40 maintained it after 1 year. CONCLUSION Irrespective of the type of organic solvent, the incorporation of high concentrations of 4-META (40 wt%) improved the resin-dentin bond stability of the experimental etch-and-rinse adhesive systems over a period of 1 year.


Effect of HEMA phosphate as an alternative to phosphoric acid for dentin treatment prior to hybridization with etch-and-rinse adhesive systems
T. Foscaldo, Glauco Botelho dos SANTOS, L. Miragaya, M. Garcia, V. Hass and E. D. da Silva
Journal of Adhesive Dentistry, ISSN: 14615185, eISSN: 17579988, Pages: 425-434, Published: 2016
PURPOSE To evaluate the effect of dentin treatment using HEMA phosphate (HEMA-P) on the microtensile bond strength (μTBS) and nanoleakage of an etch-and-rinse adhesive system. MATERIALS AND METHODS The occlusal surfaces of human molars were wet ground until superficial dentin was exposed. The specimens were then assigned to two groups according to dentin treatment: PA: 37% H₃PO₄ for 15 s; or HP: HEMA-P for 15 s. Adper Single Bond 2 was applied to the treated dentin surfaces and resin composite buildups were incrementally constructed over them. After 24-h storage in artificial saliva at 37°C, the bonded teeth were cut into resin-dentin sticks with a cross-sectional area of 1 mm², which were submitted to μTBS testing immediately or after 3 months of storage in artificial saliva at 37°C. Nanoleakage was assessed using SEM/EDS, and the interaction between dentin and H₃PO₄ or HEMA-P was evaluated by combining micro-Raman and FT-IR spectroscopy. The data were analyzed using two-way ANOVA and Tukey's HSD post-hoc test (α = 0.05). RESULTS HP presented significantly higher μTBS than PA at both times (p < 0.05). Both treatments maintained μTBS stability after 3 months of artificial saliva storage (p > 0.005). At both times, PA presented higher nanoleakage than HP (p < 0.05). CONCLUSIONS Both dentin treatments maintained μTBS stability after 3 months of artificial saliva storage. The use of HEMA-P was associated with less nanoleakage than was traditional phosphoric-acid etching.


Experimental etch-and-rinse adhesive systems containing MMP-inhibitors: Physicochemical characterization and resin-dentin bonding stability
Eduardo Moreira da Silva, Carolina Ullmann Fernandes de Sá Rodrigues, Marcos Paulo de Oliveira Matos, Thais Rodrigues de Carvalho, Glauco Botelho dos Santos, and Cristiane Mariote Amaral
Journal of Dentistry, ISSN: 03005712, Pages: 1491-1497, Published: 1 December 2015 Elsevier BV
OBJECTIVES To evaluate the degree of conversion (DC%), water sorption (WS), solubility (SO) and the resin-dentin bonding stability (μTBS) of experimental (EXP) etch-and-rinse adhesive systems containing MMP-inhibitors: Galardin-GAL, Batimastat-BAT, GM1489-GM1 and chlorhexidine diacetate-CHX. METHODS DC% was measured using FT-IR spectroscopy, while WS and SO were calculated based on ISO4049. Thirty-six human molars were wet ground until the occlusal dentin was exposed. The adhesive systems were applied and resin composite buildups were incrementally constructed. After 24 h immersion in distilled water at 37 °C, the specimens were cut into resin-dentin beams with a cross-sectional area of 1 mm(2). The μTBS was evaluated after 24 h, 6 months and 12 months of water storage at 37 °C. Adper Single Bond 2 (SB2) was used as a commercial control. The data were analyzed using ANOVA and Tukey's HSD test. RESULTS SB2 presented the highest DC% (p<0.05). CHX presented the lowest WS (p<0.05). GM1, GAL and BAT presented similar WS when compared with SB2 (p>0.05). SO was found to be not significant (p>0.05). All adhesive systems maintained μTBS stability after 6 months of water storage. Only BAT, GM1 and CHX maintained μTBs stability after 12 months of water storage. CONCLUSIONS The experimental adhesive systems with GM1489 and chlorhexidine diacetate presented the best physicochemical properties and preserved resin-dentin bonding stability after 12 months of water storage. CLINICAL SIGNIFICANCE GM1489 could be suitable for inclusion as an MMP-inhibitor in etch-and-rinse adhesive systems to maintain resin-dentin bonding stability over time.


Amalgam and resin composite longevity of posterior restorations: A systematic review and meta-analysis
Vittorio Moraschini, Cheung Ka Fai, Raphael Monte Alto, and Gustavo Oliveira dos Santos
Journal of Dentistry, ISSN: 03005712, Pages: 1043-1050, Published: 1 September 2015 Elsevier BV
OBJECTIVES The aim of the present review was to evaluate by means of a systematic review and meta-analysis the hypothesis of no difference in failure rates between amalgam and composite resin posterior restorations. DATA Randomized controlled trials, controlled clinical trials and prospective and retrospective cohort studies were included in this review. The eligibility criteria included clinical trials in humans with at least 12 months of follow-up comparing the failures rates between occlusal and occlusoproximal amalgam and composite resin restorations. Clinical questions were formulated and organized according to the PICOS strategy. SOURCE An electronic search without restriction on the dates or languages was performed in PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, and Web of Science up until March 2015. STUDY SELECTION The initial search resulted in 938 articles from PubMed/MEDLINE, 89 titles from the Cochrane Central Register of Controlled Trials, and 172 from the Web of Science. After an initial assessment and careful reading, 8 studies published between 1992 and 2013 were included in this review. According to the risk of bias evaluation, all studies were classified as high quality. CONCLUSIONS The results of this review suggest that composite resin restorations in posterior teeth still have less longevity and a higher number of secondary caries when compared to amalgam restorations. In relation to fractures, there was no statistically significant difference between the two restorative materials regarding the time of follow-up. CLINICAL SIGNIFICANCE There is currently a worldwide trend towards replacing amalgam restorations with mercury-free materials, which are adhesive and promote aesthetics. It is important to perform an updated periodic review to synthesize the clinical performance of restorations in the long-term.


Light transmission on dental resin composites
G.B. dos Santos, R.V. Monte Alto, H.R. Sampaio Filho, E.M. da Silva, and C.E. Fellows
Dental Materials, ISSN: 01095641, Pages: 571-576, Published: May 2008 Elsevier BV
OBJECTIVES The purposes of this study was: (1) to examine the light transmittance characteristics of two light-cured resin composites, for different thickness, (2) to correlate the light transmittance through the resin composites and the filler contents, and (3) to determine the penetration depth of the light as a function of the wavelength. METHODS Two resin composites (Filtek Z250, shade A2 and Filtek Supreme XT, shade A2E) were used. Specimens of six different thicknesses (0.15, 0.25, 0.30, 0.36, 0.47 and 0.75 mm) were prepared (n=3). The transmittance at wavelengths from 400 to 800 nm was measured using a UV-visible spectrophotometer, before and after light polymerization. RESULTS AND SIGNIFICANCE Significant differences were found in the wavelength dependence of transmittance between the two materials, and between the unpolymerized and polymerized stages of each resin composite. At lower wavelengths, the light transmittance of the Filtek Supreme XT resin composite was lower than the Filtek Z250. At the higher wavelengths, however, Filtek Supreme XT presented higher light transmittance. For both resin composites, the penetration depth was higher after polymerization. However, Filtek Supreme XT showed a higher gain in transmittance at the 0.15 mm thickness. The difference in light transmittance characteristics of the resin composites may affect their depth of polymerization.


The influence of C-factor, flexural modulus and viscous flow on gap formation in resin composite restorations
E. Moreira da Silva, G. O. dos Santos, J. G. A. Guimarães, A. A. L. Barcellos, and E. M. Sampaio
Operative Dentistry, ISSN: 03617734, Pages: 356-362, Published: July 2007 Operative Dentistry
Clinical Relevance Resin composites with high viscous flow and low flexural modulus may reduce gap formation in resin composite restorations.


Analysis of gap formation at tooth-composite resin interface: Effect of C-factor and lightcuring protocol
Gustavo Oliveira dos Santos, Antônio Henrique Monteiro da Fonseca Thomé da Silva, José Guilherme Antunes Guimarães, Alexandre de Araújo Lima Barcellos, Eduardo Martins Sampaio, and Eduardo Moreira da Silva
Journal of Applied Oral Science, ISSN: 16787757, eISSN: 16787765, Pages: 270-274, Published: July/August 2007 FapUNIFESP (SciELO)
Objective: The aim of this study was to evaluate the effect of C-factor and light-curing protocol on gap formation in composite resin restorations. Material and Methods: Cylindrical cavities with 5.0 mm diameter and three different depths (A=1.0, B=2.0 and C=3.0 mm) were prepared on the occlusal surface of 30 human molars and restored in a single increment with P 60. The composite resin was light-cured according to two protocols: standard - 850 mW/cm2 / 20 s and gradual - 100 up to 1000 mW/cm2/ 10 s + 1000 mW/cm2 / 10 s. After storage in distilled water (37°C/7 days), the restorations were cut into three slices in a buccolingual direction and the gap widths were analyzed using a 3D-scanning system. The data were submitted to ANOVA and Student-Newman-Keuls test (α=0.05). Results: ANOVA detected a significant influence for the C-factor and light-curing protocol as independent factors, and for the double interaction C-factor vs. light-curing protocol. Cavities with higher C-factor presented the highest gap formation. The gradual light-curing protocol led to smaller gap formation at cavity interfaces. Conclusions: The findings of this study suggest that the C-factor played an essential role in gap formation. The gradual light-curing protocol may allow relaxation of composite resin restoration during polymerization reaction.

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

Light transmission on dental resin composites
CEF G B dos Santos,R V Monte Alto,H R Sampaio Filho, E M da Silva
Dental Materials 24 (5), 571-576 127* 2008

Composite depth of cure obtained with QTH and LED units assessed by microhardness and micro-Raman spectroscopy
GB Santos, IS Medeiros, CE Fellows, A Muench, RR Braga
Operative dentistry 32 (1), 79-83 92 2007

Experimental etch-and-rinse adhesive systems containing MMP-inhibitors: Physicochemical characterization and resin-dentin bonding stability
EM da Silva, CUF de Sá Rodrigues, MP de Oliveira Matos, ...
Journal of dentistry 43 (12), 1491-1497 21 2015

Effect of intra-oral aging on t→ m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics
LM Miragaya, RB Guimarães, ROA e Souza, G dos Santos Botelho, ...
Journal of the Mechanical Behavior of Biomedical Materials 72, 14-21 16 2017

Resin-dentin bond stability of experimental 4-META-based etch-and-rinse adhesives solvated by ethanol or acetone
CM Amaral, AM Diniz, EB Arantes, GB Dos Santos, JD Noronha-Filho, ...
J Adhes Dent 18 (6), 513-520 11 2016

Effect of different times of nonthermal argon plasma treatment on the microtensile bond strength of self-adhesive resin cement to yttria-stabilized tetragonal zirconia …
AB Elias, RA Simão, M Prado, PF Cesar, GB dos Santos, EM da Silva
The Journal of prosthetic dentistry 121 (3), 485-491 8 2019

ZnCl2 incorporated into experimental adhesives: selected physicochemical properties and resin-dentin bonding stability
GS Almeida, EM da Silva, JGA Guimarães, RNL da Silva, GB Dos Santos, ...
BioMed Research International 2017 4 2017

Effect of HEMA Phosphate as an Alternative to Phosphoric Acid for Dentin Treatment Prior to Hybridization with Etchand-Rinse Adhesive Systems.
T Foscaldo, GB Dos Santos, LM Miragaya, M Garcia, V Hass, EM da Silva
Journal of Adhesive Dentistry 18 (5) 4 2016

Characterization of conventional and high-translucency Y-TZP dental ceramics submitted to air abrasion
BO Tostes, RB Guimarães, JD Noronha-Filho, GS Botelho, ...
Brazilian Dental Journal 28 (1), 97-104 3 2017

Uso de sistema de fibras de reforço em prótese adesiva posterior: relato de caso clínico
RV Monte-Alto, GO Santos, GB Santos, KRHC Dias, MS Miranda
Rev. dental press estét, 102-114 2 2009

Influence of brushing on enamel surface morphology submitted to a bleaching gel.
JH Correa, VM Valadao, GB Santos, RVM Alto, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 185-185 2 2003

Resin-dentin bond stability of etch-and-rinse adhesive systems with different concentrations of MMP inhibitor GM1489
MESNG MIRANDA, EM SILVA, MF OLIVEIRA, FS Simmer, GB SANTOS, ...
Journal of Applied Oral Science 28 2020

Influência do Protocolo de Fotoativação na Cimentação de Pinos de Fibra de Vidro
LC Pegado, AG Penelas, GB Santos, JGA Guimarães
Journal of Health Sciences 19 (5), 58-58 2017

Restauração de dentes tratados endodonticamente com pino de fibra de vidro e acessório em canais amplos
RVM Alto, GB Santos, RSMS Lima, LT Poskus, EM Silva, MS Miranda
Clín. int. j. braz. dent, 60-68 2009

Influence of a light-curing protocol on the polymerization depth of a restorative composite material.
LMN Pimentel, RVM Alto, RC Coviello, GB Santos, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 184-184 2003

Evaluation of a softstart technique of a light-curing unit.
GB Santos, RVM Alto, CF Santos, JGA Guimaraes, EM Silva, A Muench
JOURNAL OF DENTAL RESEARCH 82, 280-280 2003

Effect of storage in water on dentin bonding using two adhesive systems.
CCG Nogueira, GB Santos, RC Coviello, JGA Guimaraes, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 183-183 2003

Influence of two dentinal treatments following contamination with blood and/or saliva on bond strength to bovine dentin.
RC Coviello, LMN Pimentel, GB Santos, EM Silva, JGA Guimaraes
JOURNAL OF DENTAL RESEARCH 82, 183-183 2003

Evaluation of two alternative methods for application of two adhesive systems.
CF Santos, RVM Alto, GB Santos, AAL Barcellos, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 183-183 2003

Estudo da microdureza Knoop e do grau de conversão de um compósito em função da profundidade e fontes ativadoras
GB Santos
2003

The soft start polimerization effect on shear bond strength of two-dentin bonding agents
AB Vasconcellos, EM Silva, AAL Barcellos, GB Santos, RVM Alto, ...
JOURNAL OF DENTAL RESEARCH 81, B128-B128 2002

SoftStart polymerization influence in microleakage of resin composite restorations.
PA Lopez, EM Silva, RP Mattos, RO Campany, GB Santos, LMN Pimentel
JOURNAL OF DENTAL RESEARCH 81, B127-B127 2002

Cimento de ionomero de vidro
GB Santos
1999

Dicas: Pinos de Fibra de Vidro Personalizados
RV Monte-Alto, GB dos Santos, GO dos Santos, J Noronha