Glauco Botelho dos Santos

@uff.br

Departamento de Odontologia Restauradora
Universidade Federal Fluminense

EDUCATION

Graduação em Odontologia pela Faculdade de Odontologia de Nova Friburgo (1997), é especialista em Dentística pela USP (1999) e Implantodontia (2015), mestre em Odontologia (Materiais Dentários) pela Universidade de São Paulo (2003) e doutor em Odontologia (Dentística) pela UERJ (2008)

RESEARCH INTERESTS

COMPÓSITOS, CERÂMICAS, FOTOATIVAÇÃO

FUTURE PROJECTS

Desenvolvimento de materiais e de técnicas restauradoras adesivas objetivando a melhoria no desempenho e na longevidade dos procedimentos restauradores

Os objetivos específicos deste projeto são: 1) Caracterizar um sistema adesivo experimental de dois frascos, contendo diferentes concentrações (1%, 3% e 5%) de silicato de sódio e silicato de magnésio visando avaliar propriedades de selamento, resistência mecânica, biocompatibilidade e efeitos antimicrobianos. 2) Avaliar a efetividade de técnicas de tratamento da dentina visando melhorias na adesividade e na diminuição da permeabilidade dentinária/ sensibilidade pós-operatória..


Applications Invited
21

Scopus Publications

Scopus Publications

  • Accuracy of artificial intelligence in implant dentistry: A scoping review with systematic evidence mapping
    Vittorio Moraschini, Daniel Costa Ferreira de Almeida, Rafael Seabra Louro, Alice Maria de Oliveira Silva, Mario Pereira Couto Neto, et al.
    Journal of Prosthetic Dentistry, 2025
  • Effects of magnification on restorative dental preparation performance: a scoping review and level of evidence mapping
    Fernando Alexandria Soares de Oliveira, Vittorio Moraschini, Daniel Costa Ferreira de Almeida, Gustavo Oliveira dos Santos
    Clinical Oral Investigations, 2024
  • Protocols for Mechanical Cleaning of the Post Space on the Bond Strength Between Root Dentin and Cementation System
    CM Alencar, JRE Verbicário dos Santos, FFA Jassé, GO dos Santos, WG Escalante-Otárola, et al.
    Operative Dentistry, 2021
    SUMMARY Objective To evaluate the effects of mechanical versus chemical cleaning protocols for cleaning the root dentin surface before cementation of fiberglass posts for their effect on the bond strength, failure mode, and dentinal penetration of the cementing agent using an etch-and-rinse adhesive system on dentin prepared to receive a fiberglass post. Methods Forty roots of bovine teeth were endodontically treated and prepared for fiber post cementation. The specimens were randomized into 4 groups of 10: Control group (CO) - irrigation with 2.5% NaOCl; DW group- irrigation with distilled water; RB group - rotating brush for cleaning root canals, and CUI group - continuous ultrasonic irrigation. The fiberglass posts were cemented, and the specimens were immersed in distilled water for 6 months. A push-out test was performed on the cervical, middle, and apical thirds of the samples. Dentinal penetration of the cementing agent and the fracture pattern were evaluated by laser confocal microscopy. Statistical analysis was performed using analysis of variance (ANOVA) and post hoc Tukey tests (α=0.05). Results: The RB and CUI groups showed significantly higher bond strength values when compared to the Control and DW groups (p<0.05). In addition, in the control and DW groups, the apical third presented lower bond strength values when compared to middle and cervical thirds. Conclusion While DW showed the highest incidence of adhesive type failure, CUI resulted in the highest dentinal penetration of the cementing agent (p<0.05). RB and CUI resulted in the highest bond strength between cementation system and root dentin. In addition, CUI favored greater dentinal penetration of fiberglass post cementing agent.
  • Evaluation of Surgical Gown Textiles for Resistance Against Aerosols: A Preclinical Double-Blind Study
    Eliane Porto Barboza, Gustavo Oliveira dos Santos, Caroline Montez, Luiza Abreu Sendra, Esio de Oliveira Vieira, et al.
    Frontiers in Dental Medicine, 2021
    Personal protective equipment is used to prevent healthcare workers from contaminants. With the advent of COVID-19 pandemic, the use of effective PPE becomes more critical to avoiding infection by SARS-CoV-2. This preclinical double-blind study evaluated the performance of surgical gown textiles for penetration resistance against aerosols. The different textiles were divided into seven groups: (1) SMS PP OE Phobic; (2) Laminated Phobic; (3) Medical Barrier; (4) Trilayer Fabric; (5) Impermeable gown; (6) Impermeable with heat sealing tape; and (7) Clean Wear. All groups were exposed to aerosol-generating procedure for 5 min, according to Barboza et al. 2020. All measurements were recorded and exported to a datasheet for analysis using SPSS software. The groups showed significant differences (p < 0.01). Groups 2, 3, 4, 5, and 6 proved to be effective barriers against aerosols and presented a constant behavior. Groups 1 and 7 showed pigmented areas of 13.05 and 48.23%, respectively, suggesting that, in the present test model, these water-repellent and antimicrobial fabrics were not effective barriers against 5-min aerosols generated by a high-speed dental handpiece. Polyethylene or polyurethane laminated fabrics were efficient against 5-min aerosols. The SMS textile, globally used for surgical gowns, and the cotton fabric, impregnated with nanoparticles, were not effective barriers. The breathability and comfort of these textiles should be tested in future studies. Healthcare workers should be aware of the exact specifications of their surgical gown textiles.
  • Are Non-woven Gowns Safe for Dental Professionals? A Preclinical Double-Blind Study
    Eliane Porto Barboza, Gustavo Oliveira dos Santos, Caroline Montez, Luiza Abreu Sendra, Esio Oliveira Vieira, et al.
    Frontiers in Dental Medicine, 2020
    With the advent of the coronavirus disease 2019 (COVID-19) pandemic, the risk of dental professional's infection increases exponentially due to aerosol-generating procedures. The protective performance of dental professional gown fabrics is a major challenge against microorganisms and aerosols. Globally, health care workers wear gowns manufactured with non-woven fabrics. However, these professionals may have a false greater sense of protection based on the greater weight of the gown's fabric. This study evaluated whether aerosol generated by dental procedures has the potential to pass through three different non-woven weights (40, 60, and 80 g/m2). Single and folded formats of each weight were analyzed. The positions of the mannequin and the high-speed handpiece were standardized. The non-woven samples were placed over a sheet of sulfite paper and fixed on a marked position of a standardized smooth surface, 10 cm away from the end of the mannequin's head, simulating the dental professional body. For better visualization, the water used in the equipment was tinted with water-soluble red artificial dye. Blind to the nature of the groups, one researcher started the 5 uninterrupted min of aerosol production. The sheets were randomized coded, so that the samples could not be identified by the evaluator. Another researcher, blind to the tests, scanned all sheets and the images were analyzed by ImageJ software. The groups showed significant differences (p < 0.01). Except for the folded 80 g/m2, all groups presented pigmented mean areas ranging from 16.18% (60 g/m2 folded) to 35.68% (40 g/m2 single), suggesting that the one-layer non-woven samples were not effective as barriers for 5 uninterrupted min of aerosol spray. Dental procedures exceeding the studied time may provide different results with the non-woven 80 g/m2 folded. Dental health workers, who are exposed daily to aerosol-generating procedures, should be aware of the exact specification and performance of the fabrics used in the manufacturing of their disposable garments. If the use of an impermeable surgical gown is not possible during aerosol-generating procedures, a plastic garment associated with a disposable gown should be worn, as recommended by the World Health Organization.
  • Impact of bisphosphonate therapy on dental implant outcomes: An overview of systematic review evidence
    V. Mendes, G.O. dos Santos, M.D. Calasans-Maia, J.M. Granjeiro, V. Moraschini
    International Journal of Oral and Maxillofacial Surgery, 2019
    The purpose of this overview was to assess the methods, quality, and outcomes of systematic reviews conducted to evaluate the impact of bisphosphonates on dental implants and the risk of developing bisphosphonate-related osteonecrosis of the jaw after dental implant surgery. An electronic search without date or language restriction was performed in the PubMed/MEDLINE, Cochrane CENTRAL, Web of Science, and LILACS databases (to January 2018). Eligibility criteria included systematic reviews that evaluated the impact of bisphosphonates on implant outcomes. The quality assessment of the included reviews was done using AMSTAR 2 guidelines. The protocol of this overview was registered in PROSPERO (CRD42018089617). The search and selection process yielded seven reviews, published between 2009 and 2017. None of the systematic reviews included in this study obtained the maximum score in the quality assessment. The scientific evidence available demonstrates that patients with a history of bisphosphonate use do not present a higher risk of dental implant failure or marginal bone loss compared to patients who have not used bisphosphonates. The literature also suggests that patients who undergo surgical trauma during the installation of dental implants may be more susceptible to bisphosphonate-related osteonecrosis of the jaw.
  • Effect of different times of nonthermal argon plasma treatment on the microtensile bond strength of self-adhesive resin cement to yttria-stabilized tetragonal zirconia polycrystal ceramic
    Alexandre Barboza Elias, Renata Antoun Simão, Maíra Prado, Paulo Francisco Cesar, Glauco Botelho dos Santos, et al.
    Journal of Prosthetic Dentistry, 2019
    Statement of problem. Nonthermal argon plasma may increase the surface energy of yttria‐stabilized tetragonal zirconia polycrystal (Y‐TZP) dental ceramics. However, studies that evaluated the effect of increased plasma treatment times on the bond strength of resin cements to Y‐TZP ceramics are lacking. Purpose. The purpose of this in vitro study was to evaluate the effect of different nonthermal argon plasma (NTAP) treatment times on the surface energy and bond strength of a self‐adhesive resin cement to Y‐TZP ceramic. Material and methods. Forty‐eighty Y‐TZP plates were divided into 2 groups (n=24): as‐sintered (AS) and airborne‐particle abrasion (APA) with 50‐&mgr;m Al2O3, which were subdivided into 4 groups (n=6) according to the time of NTAP treatment: 0, 20, 60, and 120 seconds. The surface energy was evaluated with a goniometer. Forty Y‐TZP blocks submitted to the same surface treatments (8 groups; n=5) were cemented to composite resin blocks, using a self‐adhesive resin cement. After storage in distilled water at 37°C for 24 hours, the Y‐TZP‐composite resin blocks were cut into beams and submitted to a microtensile bond strength (&mgr;TBS) test. Data were analyzed using 2‐way ANOVA and the Tukey honestly significant differences test (&agr;=.05). Results. Treatment with NTAP increased the surface energy for AS and APA groups (P<.05). For both groups, the &mgr;TBS was as follows: 0 seconds < 20 seconds < 60 seconds = 120 seconds (P<.05). Only after 120 seconds of NTAP treatment was the &mgr;TBS of APA higher than that of AS (P<.05). Conclusions. Treatment with NTAP improved the surface energy and increased the &mgr;TBS of self‐adhesive resin cement to Y‐TZP ceramic, with higher times of plasma treatment resulting in higher bond strength.
  • Erratum to “Interrelation of periodontal parameters between asthmatics and nonasthmatics subjects: A systematic review and meta-analysis” [J. Dent. 69 (2018) 32–40] (Journal of Dentistry (2018) 69 (32–40), (S0300571217302932) (10.1016/j.jdent.2017.11.011))
    Vivian Mendes, Gustavo Oliveira dos Santos, Vittorio Moraschini
    Journal of Dentistry, 2018
  • Effectiveness for dentin hypersensitivity treatment of non-carious cervical lesions: a meta-analysis
    Vittorio Moraschini, Larissa Salina da Costa, Gustavo Oliveira dos Santos
    Clinical Oral Investigations, 2018
    ObjectiveThe aim of this review is to conduct a systematic review and meta-analysis comparing the effectiveness of in-home or in-office treatments for dentin hypersensitivity.Materials and methodsAn electronic search without restriction on dates or languages was performed in four electronic databases until March 2017. In addition, hand-searches in regular journals and in the gray literature were also conducted. To develop the search strategy, clinical questions were formulated using the PICOS method. Eligibility criteria included randomized clinical trials (RCTs) that compared the effectiveness of different agents for the treatment of dentin hypersensitivity through chemical occlusion, physical occlusion, nerve desensitization, or photobiomodulation (low-level light therapy). This systematic review was registered in PROSPERO under number CRD42016039394.ResultsTwenty-five RCTs (16 parallel; 9 split-mouth), published from 1992 to 2016, were included. The results of the meta-analysis showed that in-office subgroups treated with chemical or physical occlusion of dentin tubules and nerve desensitization had a statistically significant difference from placebo, with P < 0.00001, P < 0.00001, and P = 0.02, respectively. For in-home treatments, the results of the meta-analysis showed that only those subgroups treated with chemical occlusion of dentin tubules and nerve desensitization exhibited a statistically significant difference from placebo, with P < 0.00001 and P = 0.03, respectively.ConclusionsThe results of pairwise meta-analysis suggest that among in-office treatments, dentinal tubule occlusion (whether chemical or physical) and nerve desensitization provide the best outcomes for treatment of dentin hypersensitivity. For in-home treatments, only chemical occlusion of dentin tubules and nerve desensitization showed a greater treatment efficacy than placebo and the difference was statistically significant.
  • Interrelation of periodontal parameters between asthmatics and nonasthmatics subjects: a systematic review and meta-analysis
    Vivian Mendes, Gustavo Oliveira dos Santos, Vittorio Moraschini
    Journal of Dentistry, 2018
    BACKGROUND The aim of this systematic review (SR) is to evaluate the association between asthma and periodontal parameters. METHODS An electronic search without date or language restrictions ​​was carried out in MEDLINE, Cochrane, Web of Science, and LILACS until May 2017. In addition, manual search and in the grey literature were also conducted. The search process, data analysis, and quality assessment were performed by two independent reviewing authors. Eligibility criteria included prospective and retrospective cohort studies, case-controls, and randomized clinical trials. For the meta-analysis, the inverse variance method was used in fixed or random effect models, which were chosen according to heterogeneity. The estimates of the intervention effects were expressed as the mean differences. RESULTS The search and selection process yielded 21 studies, published between 1979 and 2017. The meta-analysis showed a statistically significant difference for the parameters of gingival bleeding, plaque index, and gingival index for asthmatic participants with P<0.0001, P<0.0001, and P=0.0005, respectively. CONCLUSIONS The data from this SR suggest that asthmatic patients may be more susceptible to negative periodontal changes, althought further high-quality research wuold be welcome.
  • Noninvasive approach to esthetic rehabilitation of conoid anterior teeth
    General Dentistry, 2017
  • Effect of intra-oral aging on t→m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics
    Luciana Meireles Miragaya, Renato Bastos Guimarães, Rodrigo Othávio de Assunção e Souza, Glauco dos Santos Botelho, José Guilherme Antunes Guimarães, et al.
    Journal of the Mechanical Behavior of Biomedical Materials, 2017
  • Characterization of conventional and high-translucency Y-TZP dental ceramics submitted to air abrasion
    Bhenya Ottoni Tostes, Renato Bastos Guimarães, Jaime Dutra Noronha-Filho, Glauco dos Santos Botelho, José Guilherme Antunes Guimarães, et al.
    Brazilian Dental Journal, 2017
  • ZnCl2 Incorporated into Experimental Adhesives: Selected Physicochemical Properties and Resin-Dentin Bonding Stability
    Giselle Soares Almeida, Eduardo Moreira da Silva, José Guilherme Antunes Guimarães, Rayssa Nogueira Lamego da Silva, Glauco Botelho dos Santos, et al.
    Biomed Research International, 2017
  • Effect of HEMA phosphate as an alternative to phosphoric acid for dentin treatment prior to hybridization with etch-and-rinse adhesive systems
    T. Foscaldo, Glauco Botelho dos SANTOS, L. Miragaya, M. Garcia, V. Hass, et al.
    Journal of Adhesive Dentistry, 2016
  • Resin-dentin bond stability of experimental 4-META-based etch-and-rinse adhesives solvated by ethanol or acetone
    C. Amaral, Alice Marques Diniz, Eugênio Braz Rodrigues Arantes, Glauco Botelho dos SANTOS, J. D. Noronha-Filho, et al.
    Journal of Adhesive Dentistry, 2016
  • Experimental etch-and-rinse adhesive systems containing MMP-inhibitors: Physicochemical characterization and resin-dentin bonding stability
    Eduardo Moreira da Silva, Carolina Ullmann Fernandes de Sá Rodrigues, Marcos Paulo de Oliveira Matos, Thais Rodrigues de Carvalho, Glauco Botelho dos Santos, et al.
    Journal of Dentistry, 2015
  • Amalgam and resin composite longevity of posterior restorations: A systematic review and meta-analysis
    Vittorio Moraschini, Cheung Ka Fai, Raphael Monte Alto, Gustavo Oliveira dos Santos
    Journal of Dentistry, 2015
  • Light transmission on dental resin composites
    G.B. dos Santos, R.V. Monte Alto, H.R. Sampaio Filho, E.M. da Silva, C.E. Fellows
    Dental Materials, 2008
  • The influence of C-factor, flexural modulus and viscous flow on gap formation in resin composite restorations
    E. Moreira da Silva, G. O. dos Santos, J. G. A. Guimarães, A. A. L. Barcellos, E. M. Sampaio
    Operative Dentistry, 2007
  • Analysis of gap formation at tooth-composite resin interface: Effect of C-factor and lightcuring protocol
    Gustavo Oliveira dos Santos, Antônio Henrique Monteiro da Fonseca Thomé da Silva, José Guilherme Antunes Guimarães, Alexandre de Araújo Lima Barcellos, Eduardo Martins Sampaio, et al.
    Journal of Applied Oral Science, 2007

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

Light transmission on dental resin composites
CEF G B dos Santos,R V Monte Alto,H R Sampaio Filho, E M da Silva
Dental Materials 24 (5), 571-576 127* 2008

Composite depth of cure obtained with QTH and LED units assessed by microhardness and micro-Raman spectroscopy
GB Santos, IS Medeiros, CE Fellows, A Muench, RR Braga
Operative dentistry 32 (1), 79-83 92 2007

Experimental etch-and-rinse adhesive systems containing MMP-inhibitors: Physicochemical characterization and resin-dentin bonding stability
EM da Silva, CUF de Sá Rodrigues, MP de Oliveira Matos, ...
Journal of dentistry 43 (12), 1491-1497 21 2015

Effect of intra-oral aging on t→ m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics
LM Miragaya, RB Guimarães, ROA e Souza, G dos Santos Botelho, ...
Journal of the Mechanical Behavior of Biomedical Materials 72, 14-21 16 2017

Resin-dentin bond stability of experimental 4-META-based etch-and-rinse adhesives solvated by ethanol or acetone
CM Amaral, AM Diniz, EB Arantes, GB Dos Santos, JD Noronha-Filho, ...
J Adhes Dent 18 (6), 513-520 11 2016

Effect of different times of nonthermal argon plasma treatment on the microtensile bond strength of self-adhesive resin cement to yttria-stabilized tetragonal zirconia …
AB Elias, RA Simão, M Prado, PF Cesar, GB dos Santos, EM da Silva
The Journal of prosthetic dentistry 121 (3), 485-491 8 2019

ZnCl2 incorporated into experimental adhesives: selected physicochemical properties and resin-dentin bonding stability
GS Almeida, EM da Silva, JGA Guimarães, RNL da Silva, GB Dos Santos, ...
BioMed Research International 2017 4 2017

Effect of HEMA Phosphate as an Alternative to Phosphoric Acid for Dentin Treatment Prior to Hybridization with Etchand-Rinse Adhesive Systems.
T Foscaldo, GB Dos Santos, LM Miragaya, M Garcia, V Hass, EM da Silva
Journal of Adhesive Dentistry 18 (5) 4 2016

Characterization of conventional and high-translucency Y-TZP dental ceramics submitted to air abrasion
BO Tostes, RB Guimarães, JD Noronha-Filho, GS Botelho, ...
Brazilian Dental Journal 28 (1), 97-104 3 2017

Uso de sistema de fibras de reforço em prótese adesiva posterior: relato de caso clínico
RV Monte-Alto, GO Santos, GB Santos, KRHC Dias, MS Miranda
Rev. dental press estét, 102-114 2 2009

Influence of brushing on enamel surface morphology submitted to a bleaching gel.
JH Correa, VM Valadao, GB Santos, RVM Alto, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 185-185 2 2003

Resin-dentin bond stability of etch-and-rinse adhesive systems with different concentrations of MMP inhibitor GM1489
MESNG MIRANDA, EM SILVA, MF OLIVEIRA, FS Simmer, GB SANTOS, ...
Journal of Applied Oral Science 28 2020

Influência do Protocolo de Fotoativação na Cimentação de Pinos de Fibra de Vidro
LC Pegado, AG Penelas, GB Santos, JGA Guimarães
Journal of Health Sciences 19 (5), 58-58 2017

Restauração de dentes tratados endodonticamente com pino de fibra de vidro e acessório em canais amplos
RVM Alto, GB Santos, RSMS Lima, LT Poskus, EM Silva, MS Miranda
Clín. int. j. braz. dent, 60-68 2009

Influence of a light-curing protocol on the polymerization depth of a restorative composite material.
LMN Pimentel, RVM Alto, RC Coviello, GB Santos, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 184-184 2003

Evaluation of a softstart technique of a light-curing unit.
GB Santos, RVM Alto, CF Santos, JGA Guimaraes, EM Silva, A Muench
JOURNAL OF DENTAL RESEARCH 82, 280-280 2003

Effect of storage in water on dentin bonding using two adhesive systems.
CCG Nogueira, GB Santos, RC Coviello, JGA Guimaraes, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 183-183 2003

Influence of two dentinal treatments following contamination with blood and/or saliva on bond strength to bovine dentin.
RC Coviello, LMN Pimentel, GB Santos, EM Silva, JGA Guimaraes
JOURNAL OF DENTAL RESEARCH 82, 183-183 2003

Evaluation of two alternative methods for application of two adhesive systems.
CF Santos, RVM Alto, GB Santos, AAL Barcellos, EM Silva
JOURNAL OF DENTAL RESEARCH 82, 183-183 2003

Estudo da microdureza Knoop e do grau de conversão de um compósito em função da profundidade e fontes ativadoras
GB Santos
2003

The soft start polimerization effect on shear bond strength of two-dentin bonding agents
AB Vasconcellos, EM Silva, AAL Barcellos, GB Santos, RVM Alto, ...
JOURNAL OF DENTAL RESEARCH 81, B128-B128 2002

SoftStart polymerization influence in microleakage of resin composite restorations.
PA Lopez, EM Silva, RP Mattos, RO Campany, GB Santos, LMN Pimentel
JOURNAL OF DENTAL RESEARCH 81, B127-B127 2002

Cimento de ionomero de vidro
GB Santos
1999

Dicas: Pinos de Fibra de Vidro Personalizados
RV Monte-Alto, GB dos Santos, GO dos Santos, J Noronha