Guillermo Cano-Verdugo

@odontologia.uanl.mx

School of Dentistry
Universidad Autónoma de Nuevo León



                             

https://researchid.co/guillermocano_verdugo

I'm Guillermo Cano Verdugo, a trained dentist with a master's degree and a doctorate in science. I have dedicated the last five years to teaching, research and private practice in dentistry. During this time, I collaborated in large multidiscplinary teams to get results in benefit of oral and overall health, creating biomarkers for detection of oral lesiones and implementing interventions for promoting early detection. Additionaly, I have the amazing opportunity to colaborate in the community outreach program to support them in the promotion of their health.

EDUCATION

Bachelor in Dentistry. Master's and Doctorate in sciences.

RESEARCH, TEACHING, or OTHER INTERESTS

Public Health, Environmental and Occupational Health, Dentistry, Health, Toxicology and Mutagenesis

12

Scopus Publications

38

Scholar Citations

3

Scholar h-index

1

Scholar i10-index

Scopus Publications

  • Correction: Protocol for a systematic review and meta-analysis of the prevalence of viral infections in acute apical abscesses (BDJ Open, (2025), 11, 1, (34), 10.1038/s41405-025-00320-0)
    José Ángel Hernández-Mariano, Gustavo Adolfo Sánchez-Ramírez, Guillermo Cano-Verdugo, Myriam Angélica De la Garza-Ramos, Martín Andrés Chávez- Méndez, Claudio Peña-Soto, and Mónica Alethia Cureño-Díaz

    Springer Science and Business Media LLC

  • Protocol for a systematic review and meta-analysis of the prevalence of viral infections in acute apical abscesses
    José Ángel Hernández-Mariano, Gustavo Adolfo Sánchez-Ramírez, Guillermo Cano-Verdugo, Myriam Angélica De la Garza-Ramos, Martín Andrés Chávez- Méndez, Claudio Peña-Soto, and Mónica Alethia Cureño-Díaz

    Springer Science and Business Media LLC
    Abstract Background There is no current consensus on the presence of viral infections in acute apical abscesses; therefore, this protocol for a systematic review and meta-analysis is designed to detail the procedures required to investigate the prevalence of viral infections in acute apical abscesses, a common dental condition characterized by pus accumulation due to bacterial infection. Viral infections in oral tissues have been linked to systemic health risks, including chronic inflammation and oncogenesis, which further emphasize the importance of understanding their role in acute apical abscesses. Methods/design We adopted a systematic review and meta-analysis protocol design followed by PRISMA guidelines. A priori protocol was registered in PROSPERO with registry number: CRD42023468287. Inclusion criteria will be established according to the PICO framework; hence, we will include original articles with no restriction on publication date or population group. The selective screening of information will be conducted by peers, starting with titles, abstracts, and keywords, and finally reviewing the full text. The risk of bias will be assessed using the ROBINS tool, and the certainty of the evidence will be evaluated following the GRADE guidelines. We will perform a random-effects meta-analysis, utilizing the Freeman-Tukey double arcsine transformation, to estimate the pooled prevalence of viral infections in acute apical abscesses, assess heterogeneity using the Q-test and I² statistic, evaluate potential publication bias with funnel plots and Egger’s test, and conduct sensitivity analyses to ensure robust results. Discussion At present, no consensus exists regarding the prevalence of viral infections in acute apical abscesses that could inform clinical dental practice. Moreover, the existing body of knowledge on this subject is notably limited. This approach is intended to provide data that will facilitate the improvement of clinical practice and serve as a methodological framework for studying various pathologies. By elucidating the prevalence of viral infections, the findings of this study could enhance diagnostic accuracy and inform more targeted and effective treatment strategies, ultimately improving patient outcomes.

  • Association Between Nursing Diagnoses and Mortality in Hospitalized Patients with COVID-19: A Retrospective Cohort Study
    José Ángel Hernández-Mariano, Olivia Mendoza-Macario, María del Carmen Velázquez-Núñez, María del Carmen Cedillo-Ordaz, Blanca Estela Cervantes-Guzmán, Dulce Milagros Razo-Blanco-Hernández, Erick Alberto Landeros-Olvera, Fani Villa-Rivas, Rocío Castillo-Díaz, and Guillermo Cano-Verdugo

    MDPI AG
    Previous studies suggest that nursing diagnoses (NDs) could predict clinical outcomes, such as mortality, among patients with non-communicable diseases. However, evidence in patients with COVID-19 is still scarce. Objective: To evaluate the association between NDs and COVID-19 mortality among hospitalized patients. Methods: A retrospective cohort study was conducted on 498 paper clinical records of patients hospitalized for at least 72 h in the internal medicine unit for COVID-19 from June to December 2020. The interest association was assessed using logistic regression models. Results: NDs focused on COVID-19 pulmonary responses, such as impaired gas exchange (OR = 3.04; 95% CI = 1.87, 4.95), impaired spontaneous ventilation (OR = 3.67; 95% CI = 2.17, 6.21), or ineffective airway clearance (OR = 2.47; 95% CI = 1.48, 4.12), were significant predictors of mortality. NDs on COVID-19 extrapulmonary responses, such as risk for unstable blood glucose level (OR = 2.45; 95% CI = 1.45, 4,15), risk for impaired liver function (OR = 2.02; 95% CI = 1.11, 3.63), hyperthermia (OR = 2.08; 95% CI = 1.29, 3.35), decreased cardiac output (OR = 2.95; 95% CI = 1.42, 6.11), or risk for shock (OR = 3.03; 95% CI = 1.28, 7.13), were associated with a higher risk of in-hospital mortality. Conversely, patients with NDs of fear (OR = 0.56; 95% CI = 0.35, 0.89) and anxiety (OR = 0.44; 95% CI = 0.26, 0.77) had a lower risk of death. Conclusions: NDs on pulmonary and extrapulmonary responses to COVID-19 were associated with in-hospital mortality, suggesting that they are indicators of the severity of these patients. Therefore, NDs may help nursing staff identify individuals who require closer monitoring and guide early interventions for their recovery.

  • Protocol for a Systematic Review on the Application of Robotics in Orthodontic Treatments
    Guillermo Cano-Verdugo, Myriam Angélica De la Garza-Ramos, Omosebi Temitope Olabisi, Yinli Liu, Georgina Mayela Núñez-Rocha, María Natividad Ávila-Ortíz, and Karina Janett Hernández-Ruiz

    Global Clinical Engineering Journal
    Background and ObjectiveRobotics have various applications in dentistry, particularly in orthodontics, though the potential use of these technologies remains unclear. The objective of this protocol for a systematic review will be to describe the steps to summarize the application of robotics in orthodontics and to clarify its function and scope in clinical practice.Material and MethodsTo achieve this, original articles addressing the employment of robotics in any area of orthodontic practice will be included, while review articles will be excluded. Data will be searched in PubMed, Google Scholar, Scopus and DOAJ. The risk of bias will be established using the ROBINS-E and certainty assessment tools with GRADE guidelines.ResultsThe main results of the included articles will be tabulated in an Excel spreadsheet and a narrative synthesis of the data will be generated and presented according to its application in surgical and non-surgical orthodontics.ConclusionThe search is expected to retrieve articles for all around the world. This project will be self-financed, and a protocol is registered at the PROSPERO site with registration number CRD42023463531.

  • Antifungal and wound healing potential of calendula officinalis for dental use: an in vitro study
    Nadxiely Ixchel Ricardez-García, Myriam Angélica De la Garza-Ramos, Arturo Abraham Cienfuegos-Sarmiento, and Guillermo Cano-Verdugo

    Universidade Estadual de Campinas
    Aim: To demonstrate the antifungal and healing properties of Calendula officinalis. Methods: We included four assays: inhibition halo, germicidal test, cytotoxicity test, and scratch test. Results: The extract at 100% and 50% concentrations was effective, and both presentations (Calendula officinalis extract and Calendula officinalis infusion) exhibited no cytotoxic effects. Furthermore, the infusion demonstrated a high healing effect without affecting the morphology of the cell monolayer and promoted fibroblastic proliferation. The extract did not show the expected healing results. Conclusions: Calendula officinalis holds considerable potential for further research across various biological processes, highlighting its promise as a subject for continued investigation.

  • Virtual education and clinical practices in final-year Peruvian dentistry students during COVID-19 pandemic
    Fiorella del Pilar Cabrera-Tasayco, Martín Andrés Chávez-Méndez, Javier Flores-Fraile, Claudio Peña-Soto, Myriam Angélica De la Garza-Ramos, and Guillermo Cano-Verdugo

    Frontiers Media SA
    IntroductionThe COVID-19 pandemic has significantly altered various sectors, with education being one of the most impacted. In Peru, the shift from in-person to virtual education was imperative due to the pandemic’s constraints. This study investigates the perception of virtual education and clinical practice among final-year dentistry students at a Peruvian institution during the SARS-CoV-2 pandemic.MethodsUtilizing a cross-sectional design, data were collected from 97 students via a survey assessing their experiences and expectations related to virtual learning and clinical skills. Instruments with dichotomous response scales measured students’ experiences with virtual education and their expectations regarding clinical practice.ResultsResults indicated that most students reported a moderate experience with virtual education, with similar moderate expectations for clinical practice. Statistical analyses revealed significant differences among experience levels and practice expectations, highlighting a disparity between students’ perceived skills and their confidence in applying these skills (p < 0.001).DiscussionThe study’s findings suggest that while virtual education has provided continuity, there remains considerable room for improvement in both the quality of online instruction and practical training. Enhancements in virtual teaching methods and additional support for clinical practice could better meet the needs of dental students. This study emphasizes the importance of ongoing evaluation and adaptation of virtual education strategies to address the evolving challenges and improve educational outcomes for future dental professionals.

  • Impact of urban farming on health: a systematic review
    Guillermo Cano-Verdugo, Brianda Daniela Flores-García, Georgina Mayela Núñez-Rocha, María Natividad Ávila-Ortíz, and María Argelia Akemi Nakagoshi-Cepeda

    Oxford University Press (OUP)
    Abstract Background Urban farms are spaces designated for the cultivation of plants for food security, medicinal and curative purposes. Since the turn of the century, they have become more widespread and health benefits have been claimed; however, no consensus exists regarding this information. Hence, this study aims to provide information about the health effects of urban farming. Methods Protocol register number CRD42023448001. We followed the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Studies addressing urban farming interventions in any population group were included without age limitation of publication from PubMed, DOAJ, CAB Abstracts and NIH. Risk of bias was assessed using the Risk of Bias In Non-randomized Studies - of Interventions tool, and data were narratively synthesized. Results The search retrieved 2578 manuscripts, reduced to seven after screening. Urban farming’s impact on health has been reflected in the physical domain by increasing self-reported health levels, physical activity, perceived general health, healthy eating and decreasing drug use. Parasites’ presence has also been reported. In the mental aspect, urban farming is associated with relaxation and stress reduction. From a social perspective, urban farms provide a sense of belonging, personal growth and happiness. Conclusions The benefits of urban farming outweigh the disadvantages. Further research should be conducted to clarify the potential benefits of this practice.

  • EMPIRICAL DERIVATION APPLIED TO DIAGNOSTIC TEST RESEARCH ON NATURAL FLUORESCENT BIOMARKERS
    Guillermo Cano-Verdugo, Dora Julia Onofre-Rodríguez, Raquel Alicia Benavides-Torres, and Dafne Astrid Gómez-Melasio

    Pontificia Universidad Catolica de Chile
    INTRODUCCIÓN: La derivación de declaraciones es una estrategia creada para desarrollar enunciados acerca de un fenómeno empleando analogías entre dos campos de conocimiento. De esta forma, una declaración de un campo de conocimiento es empleada para dar origen a otra de otro campo, inclusive de otra rama del conocimiento, compartiendo una estructura o contenido en común. OBJETIVO: Desarrollar una herramienta que permita identificar la factibilidad de crear y evaluar biomarcadores naturales fluorescentes, derivada de la arquitectura para investigación en pruebas diagnósticas de Gluud y Gluud. METODOLOGÍA: Para realizar el proceso de derivación de declaraciones se utilizaron los cinco pasos propuestos por Walker y Avant. DESARROLLO: Revisión exhaustiva de la arquitectura para investigación en pruebas diagnósticas de Gluud y Gluud; Indagación en literatura en ciencias biomédicas, salud pública, metodología de la investigación en ciencias de la salud, medicina molecular, física y biología; Selección de método de fluorescencia como campo de origen; Adaptación de la arquitectura para investigación en pruebas diagnósticas; Redefinición de las nuevas declaraciones. CONCLUSIÓN: La derivación de declaraciones basada en la arquitectura para investigación en pruebas diagnósticas de Gluud y Gluud es relevante, ya que permite contar con una herramienta para crear y evaluar biomarcadores naturales fluorescentes.

  • Identification of Biofilm and Potentially Malignant Lesion in Oral Cavity Using a Revealing Substance: Case Report


  • Compressive Stress in Teeth Restored with Endocrown and Build-up: A Finite Element Analysis
    Katherinne A Bardales-Espinoza, Anderson R Mora-Ipince, Martín A Chávez-Méndez, Claudio Peña-Soto, Javier Flores-Fraile, Myriam A De la Garza-Ramos, and Guillermo Cano-Verdugo

    Jaypee Brothers Medical Publishing
    AIM This study evaluates compressive stress in teeth restored with endocrown (ECW) and build-up (BUP) using finite element analysis (FEA). Understanding stress distribution in dental restorations is crucial for improving treatment outcomes and longevity. MATERIALS AND METHODS A second lower molar was modeled using Solidworks® (Version 2017). The ECW was simulated with nanoceramic resin, while the BUP included a core and nanoceramic crown. Mechanical properties, including modulus of elasticity, Poisson's ratio, and tensile strength were assigned to materials. Axial and oblique loads of 900N were applied, and stress was analyzed using Solidworks®. RESULTS Results indicated that under axial loading, ECW experienced a maximum stress of 91.9 MPa, significantly higher than BUP's 49 MPa. Under oblique loading, ECW exhibited 132 MPa compared with 116 MPa in BUP. The highest stress concentration was in the cervical area, where ECW showed greater stresses in both the substrate and restored area. Build-up demonstrated better stress distribution and lower fracture risk. CONCLUSION Endocrown restoration results in higher compressive stresses, especially in the cervical region, which may increase the risk of fracture. Conversely, the BUP technique, which preserves cervical dentin, offers improved stress distribution and reduced fracture risk, making it a more robust solution for endodontic rehabilitation. CLINICAL SIGNIFICANCE This study underscores the importance of selecting appropriate restoration methods to minimize stress and enhance the longevity of dental treatments, ultimately leading to better patient outcomes. How to cite this article: Bardales-Espinoza KA, Mora-Ipince AR, Chávez-Méndez MA, et al. Compressive Stress in Teeth Restored with Endocrown and Build-up: A Finite Element Analysis. J Contemp Dent Pract 2024;25(11):1027-1033.

  • Generalities in canine papillomavirus: systematic review of case reports
    Guillermo Cano-Verdugo, Gabriela Guadalupe Verdugo-Lizárraga, and David Emmanuel Gámez-Sánchez

    Universidad Nacional Autonoma de Mexico
    Canine papillomavirus (CPV) is a common entity in dogs that can be transmitted by direct and indirect contact and cause lesions in various parts of the body. It is the main cause of benign tumors; however, if not detected in time, it is a risk factor for the development of squamous cell carcinoma, documented with high mortality. To clarify demographic generalities, location of lesions, and findings involved in CPV detection, a systematic review of case reports of CPV was performed. The PRISMA statement was followed. Literature was searched in PubMed, DOAJ, and CAB Abstracts from 2011 to date. The articles collected were tabulated in Excel with the variables of interest. A total of 54 articles were obtained from the search, and 11 were included in the review after the screening and selection process. The analysis of the information allowed us to identify that among the case reports there were 4 investigations with male dogs, 2 females and 5 unspecified. Age ranged from 2 to 12 years. The breed with more cases reported was the Labrador retriever and 6 reported cases with neutered patients. Regarding the location of the lesions, the most common was the oral cavity, and the main findings were the need to identify new subtypes of CPV, and the development of lesions at lower CD4 and CD8 lymphocyte counts. Further research, encouragement of veterinary medical personnel, and dissemination of CPVrelated literature are needed to make this pathology visible and initiate future public health actions.

  • Nursing Staff Mortality During the Covid-19 Pandemic, Scoping Review
    Yuliana Vera-Alanis, Daysi Aranda-Sanchez, Guillermo Cano-Verdugo, Pedro Gonzalez-Angulo, Cynthia Berenice Rueda-Sanchez, and Augusto Rojas-Martinez

    SAGE Publications
    Introduction In a pandemic, the risk of infection and mortality for nurses can increase substantially. This study analyzes the information reported on the mortality of nursing personnel from different countries due to COVID-19. Methods We performed a scoping review by searching information available in PubMed, Scielo, and Google Scholar databases using concepts related to nursing, mortality, COVID-19, etc. The studies were searched from September 1 to October 30, 2021. This review included 12 articles were selected among 73 identified for the scope search because they included nurses. Results Nursing personnel presented a high mortality rate after physicians and health personnel. The average age of the deceased nurses was 43 years, being higher in men than in women. Higher mortality rates were reported in services attending COVID-19, nursing homes, and psychiatric centers. Conclusion Contagion and deaths are attributed to lack of planning and inadequate personal protective equipment.

RECENT SCHOLAR PUBLICATIONS

  • Parental function in the dental management of pediatric patients with autistic spectrum disorder: A systematic review
    MA de la Garza-Ramos, G Cano-Verdugo, AN Verdugo-Rojas, ...
    Research in Autism 123, 202558 2025

  • Association Between Nursing Diagnoses and Mortality in Hospitalized Patients with COVID-19: A Retrospective Cohort Study
    J Hernndez-Mariano, O Mendoza-Macario, MC Velzquez-Nez, ...
    Nursing Reports 15 (5), 147 2025

  • Antifungal and wound healing potential of calendula officinalis for dental use: an in vitro study
    NI Ricardez-Garca, MA Garza-Ramos, AA Cienfuegos-Sarmiento, ...
    Brazilian Journal of Oral Sciences 24, e255546 2025

  • Virtual education and clinical practices in final-year Peruvian dentistry students during COVID-19 pandemic
    F del Pilar Cabrera-Tasayco, MA Chvez-Mndez, J Flores-Fraile, ...
    Frontiers in Psychology 16, 1468949 2025

  • Virtual education and clinical practices in final-year Peruvian dentistry students during COVID-19 pandemic
    FP Cabrera-Tasayco, MA Chvez-Mndez, J Flores-Fraile, C Pea-Soto, ...
    Frontiers in Psychology 16, 1468949 2025

  • Protocol for a systematic review and meta-analysis of the prevalence of viral infections in acute apical abscesses
    J Hernndez-Mariano, GA Snchez-Ramrez, G Cano-Verdugo, ...
    BDJ open 11 (1), 34 2025

  • Protocol for a Systematic Review on the Application of Robotics in Orthodontic Treatments
    G Cano-Verdugo, MA De la Garza-Ramos, OT Olabisi, Y Liu, ...
    Global Clinical Engineering Journal 7 (1), 32-38 2025

  • Compressive Stress in Teeth Restored with Endocrown and Build-up: A Finite Element Analysis
    KA Bardales-Espinoza, AR Mora-Ipince, MA Chvez-Mndez, ...
    The Journal of Contemporary Dental Practice 25 (11), 1028 2024

  • Comparison of Two Scales of Self-perception of Body Image in Schoolchildren
    MN Avila-Ortiz, GM Nunez-Rocha, AE Castro-Sanchez, ...
    ANNALS OF NUTRITION AND METABOLISM 80, 130-131 2024

  • Salud general, estilos y calidad de vida en atletas universitarios del noreste de Mxico
    GM Nez-Rocha, G Cano-Verdugo, JA Hernndez-Morales, ...
    Horizonte sanitario 23 (3), 519-525 2024

  • Impact of urban farming on health: a systematic review
    G Cano-Verdugo, BD Flores-Garca, GM Nez-Rocha, MN vila-Ortz, ...
    Journal of Public Health 46 (3), e500-e509 2024

  • Identification of Biofilm and Potentially Malignant Lesion in Oral Cavity Using a Revealing Substance: Case Report
    G Cano-Verdugo, MA de La Garza-Ramos, DA Garcfa-Robayo
    Journal of International Dental and Medical Research 17 (2), 788-792 2024

  • Derivacin emprica aplicada a la investigacin de pruebas diagnsticas en biomarcadores naturales fluorescentes
    G Cano-Verdugo, DJ Onofre-Rodrguez, RA Benavides-Torres, ...
    Horizonte de Enfermera 35 (1), 129-143 2024

  • Application of robotics in orthodontics: A systematic review
    MA De La Garza-Ramos, HH Ipia-Lozano, G Cano-Verdugo, ...
    Cureus 16 (4) 2024

  • Relacin entre el conocimiento sobre la utilizacin del condn y su uso en adultos jvenes
    DAG Melasio, NGP Briones, GC Verdugo, AL Mendoza, EKH Martnez
    Revista de la Facultad de Ciencias Mdicas:(Quito) 49 (3), 5 2024

  • Impacto sobre la funcin sexual en hombres con cncer de mama: Revisin de alcance
    Y Vera-Alanis, G Cano-Verdugo
    Medicina e Investigacin Universidad Autnoma del Estado de Mxico 11 (2), 77-85 2023

  • Leveraging Artificial Intelligence to Revolutionize Healthcare: A Comprehensive Analysis
    G Cano-Verdugo, J Owoyemi, A Khan, MS Tahsin, DN Shukurullaevna
    SciWaveBulletin 1 (1), 12-19 2023

  • Anlisis histrico de la prevalencia de lesiones sospechosas de cncer bucal en Mxico 2009-2020
    G Cano-Verdugo, MA de la Garza-Ramos
    Revista Mdica de la Universidad Autnoma de Sinaloa REVMEDUAS 13 (3), 278-287 2023

  • Generalities in canine papillomavirus: systematic review of case reports
    G Cano-Verdugo, GG Verdugo-Lizrraga, DE Gmez-Snchez
    Veterinaria Mxico OA 10 2023

  • Nursing staff mortality during the COVID-19 pandemic, scoping review
    Y Vera-Alanis, D Aranda-Sanchez, G Cano-Verdugo, P Gonzalez-Angulo, ...
    SAGE Open Nursing 8, 23779608221119130 2022

MOST CITED SCHOLAR PUBLICATIONS

  • Nursing staff mortality during the COVID-19 pandemic, scoping review
    Y Vera-Alanis, D Aranda-Sanchez, G Cano-Verdugo, P Gonzalez-Angulo, ...
    SAGE Open Nursing 8, 23779608221119130 2022
    Citations: 14

  • Efectividad del cepillado dental de los escolares de Monterrey, Nuevo Len
    NL Monterrey
    Rev Mex Med Forense 4 (1), 82-84 2019
    Citations: 8

  • Impact of urban farming on health: a systematic review
    G Cano-Verdugo, BD Flores-Garca, GM Nez-Rocha, MN vila-Ortz, ...
    Journal of Public Health 46 (3), e500-e509 2024
    Citations: 5

  • Application of robotics in orthodontics: A systematic review
    MA De La Garza-Ramos, HH Ipia-Lozano, G Cano-Verdugo, ...
    Cureus 16 (4) 2024
    Citations: 3

  • Leveraging Artificial Intelligence to Revolutionize Healthcare: A Comprehensive Analysis
    G Cano-Verdugo, J Owoyemi, A Khan, MS Tahsin, DN Shukurullaevna
    SciWaveBulletin 1 (1), 12-19 2023
    Citations: 3

  • Impacto sobre la funcin sexual en hombres con cncer de mama: Revisin de alcance
    Y Vera-Alanis, G Cano-Verdugo
    Medicina e Investigacin Universidad Autnoma del Estado de Mxico 11 (2), 77-85 2023
    Citations: 2

  • Anlisis histrico de la prevalencia de lesiones sospechosas de cncer bucal en Mxico 2009-2020
    G Cano-Verdugo, MA de la Garza-Ramos
    Revista Mdica de la Universidad Autnoma de Sinaloa REVMEDUAS 13 (3), 278-287 2023
    Citations: 2

  • Efectividad del cepillado dental supervisado en la salud oral de los escolares de Monterrey, Nuevo Len
    G Cano Verdugo
    Universidad Autnoma de Nuevo Len 2018
    Citations: 1