Biophysics, Biochemistry, Genetics and Molecular Biology, Cell Biology, Biomedical Engineering
2516
Scholar Citations
27
Scholar h-index
47
Scholar i10-index
RECENT SCHOLAR PUBLICATIONS
Nucleus softens during herpesvirus infection A Tervonen, V Ruokolainen, S Leclerc, K Tieu, S Lyonnais, H Niskanen, ... PLoS pathogens 22 (1), e1013873 , 2026 2026
Deep Invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium E Mäntylä, S Korpela, A Rekonen, S Hakkola, J Karttunen, A Pörsti, ... bioRxiv, 2026.03. 10.710762 , 2026 2026
Biomimetic hydrogel platform reveals active force transduction from retinal pigment epithelium to photoreceptors S Korpela, M Kauppila, V Karema-Jokinen, L Sukki, P Kallio, H Skottman, ... Acta Biomaterialia 205, 537-549 , 2025 2025
Phagocytosed Photoreceptor Outer Segment Particles Within the Retinal Pigment Epithelium Show Diurnal Rhythmicity and Variation Between Cone Subtypes in Larval Zebrafish J Partinen, NE Nevala, S Erämies, TO Ihalainen, S Nymark The FASEB Journal 39 (14), e70853 , 2025 2025 Citations: 2
Circadian Rhythms in Murine Ocular Tissues Including Sclera Are Affected by Neurobasal A Medium Preincubation and Mouse Strain, but Not Sex N Milićević, C Sandu, E Challet, TO Ihalainen, S Nymark, ... Investigative Ophthalmology & Visual Science 66 (6), 62-62 , 2025 2025 Citations: 1
Viscoelasticity driven deformation dynamics of the substrate affect mechanically induced Ca2+ signals H Peussa, S Peltola, A Tervonen, S Lehtimäki, M Kauppila, R Bhati, ... bioRxiv, 2025.11. 07.687272 , 2025 2025 Citations: 2
Stabilizing light-responsive azobenzene films in an aqueous environment with thin polymer coatings M Isomäki, L Kääriäinen, C Fedele, S Lehtimäki, TP Ruoko, E Mäntylä, ... Soft Matter 21 (34), 6779-6790 , 2025 2025
Whole mount immunofluorescence analysis of fresh and stored human donor corneas highlights changes in limbal characteristics during storage M Kauppila, M Vattulainen, TO Ihalainen, A Mörö, T Ilmarinen, H Skottman The Ocular Surface 34, 50-59 , 2024 2024 Citations: 2
Iterative Immunostaining and NEDD Denoising for Improved Signal-To-Noise Ratio in ExM-LSCM L Azzari, M Vippola, S Nymark, TO Ihalainen, E Mäntylä Bio-protocol 14 (18) , 2024 2024
A system for cell culturing A Priimägi, C Fedele, T Ihalainen US Patent App. 18/692,161 , 2024 2024
Mitochondrial temperature homeostasis resists external metabolic stresses M Terzioglu, K Veeroja, T Montonen, TO Ihalainen, TS Salminen, P Bénit, ... Elife 12, RP89232 , 2023 2023 Citations: 44
Light-Induced Nanoscale Deformation in Azobenzene Thin Film Triggers Rapid Intracellular Ca2+ Increase via Mechanosensitive Cation Channels H Peussa, C Fedele, H Tran, M Marttinen, J Fadjukov, E Mäntylä, ... Advanced Science 10 (35) , 2023 2023 Citations: 11
Toward Corneal Limbus In Vitro Model: Regulation of hPSC‐LSC Phenotype by Matrix Stiffness and Topography During Cell Differentiation Process M Kauppila, A Mörö, JJ Valle‐Delgado, T Ihalainen, L Sukki, P Puistola, ... Advanced Healthcare Materials 12 (29), 2301396 , 2023 2023 Citations: 12
Substrate microtopographies induce cellular alignment and affect nuclear force transduction B Belay, E Mäntylä, C Maibohm, OF Silvestre, J Hyttinen, JB Nieder, ... Journal of the Mechanical Behavior of Biomedical Materials 146, 106069 , 2023 2023 Citations: 3
Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina E Mäntylä, T Montonen, L Azzari, S Mattola, M Hannula, M Vihinen-Ranta, ... Molecular Biology of the Cell 34 (9), br13 , 2023 2023 Citations: 8
The effect of substrate stiffness on elastic force transmission in the epithelial monolayers over short timescales A Tervonen, S Korpela, S Nymark, J Hyttinen, TO Ihalainen Cellular and Molecular Bioengineering 16 (5-6), 475 , 2023 2023 Citations: 14
Nuclear lamina strain states revealed by intermolecular force biosensor BE Danielsson, B George Abraham, E Mäntylä, JI Cabe, CR Mayer, ... Nature Communications 14 (1), 3867 , 2023 2023 Citations: 51
CDK5 activity in retinal pigment epithelium contributes to gap junction dynamics during phagocytosis J Fadjukov, S Wienbar, N Milićević, S Hakanen, M Vihinen-Ranta, ... bioRxiv, 2023.02. 09.527850 , 2023 2023
Atsobentseenit taipuvat moneen solubiologisessa tutkimuksessa H Peussa, M Isomäki, C Fedele, S Nymark, T Ihalainen, E Mäntylä, ... Solubiologi 41 (1), 9-17 , 2023 2023
Talin variant P229S compromises integrin activation and associates with multifaceted clinical symptoms L Azizi, L Varela, P Turkki, VV Mykuliak, S Korpela, TO Ihalainen, ... Human Molecular Genetics 31 (24), 4159-4172 , 2022 2022 Citations: 7
MOST CITED SCHOLAR PUBLICATIONS
Protein diffusion in mammalian cell cytoplasm T Kühn, TO Ihalainen, J Hyväluoma, N Dross, SF Willman, J Langowski, ... PLoS One 6 (8), e22962 , 2011 2011 Citations: 240
Differential basal-to-apical accessibility of lamin A/C epitopes in the nuclear lamina regulated by changes in cytoskeletal tension TO Ihalainen, L Aires, FA Herzog, R Schwartlander, J Moeller, V Vogel Nature materials 14 (12), 1252-1261 , 2015 2015 Citations: 209
Transdifferentiation and proliferation in two distinct hemocyte lineages in Drosophila melanogaster larvae after wasp infection I Anderl, L Vesala, TO Ihalainen, LM Vanha-aho, I Andó, M Rämet, ... PLoS pathogens 12 (7), e1005746 , 2016 2016 Citations: 190
Characterization of the microstructure of hydrazone crosslinked polysaccharide-based hydrogels through rheological and diffusion studies J Karvinen, TO Ihalainen, MT Calejo, I Jönkkäri, M Kellomäki Materials Science and Engineering: C 94, 1056-1066 , 2019 2019 Citations: 149
Carbon nanotubes as electrodes for dielectrophoresis of DNA S Tuukkanen, JJ Toppari, A Kuzyk, L Hirviniemi, VP Hytönen, T Ihalainen, ... Nano letters 6 (7), 1339-1343 , 2006 2006 Citations: 131
Dielectrophoresis of nanoscale double-stranded DNA and humidity effects on its electrical conductivity S Tuukkanen, A Kuzyk, JJ Toppari, VP Hytönen, T Ihalainen, P Törmä Applied Physics Letters 87 (18) , 2005 2005 Citations: 106
Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering JT Koivisto, T Joki, JE Parraga, R Pääkkönen, L Ylä-Outinen, L Salonen, ... Biomedical Materials 12 (2), 025014 , 2017 2017 Citations: 98
Internalization of novel non-viral vector TAT-streptavidin into human cells J Rinne, B Albarran, J Jylhävä, TO Ihalainen, P Kankaanpää, VP Hytönen, ... BMC biotechnology 7 (1), 1 , 2007 2007 Citations: 92
Magnetic resonance imaging of viral particle biodistribution in vivo JK Räty, T Liimatainen, T Wirth, KJ Airenne, TO Ihalainen, T Huhtala, ... Gene therapy 13 (20), 1440 , 2006 2006 Citations: 77
His-tagged norovirus-like particles: A versatile platform for cellular delivery and surface display T Koho, TO Ihalainen, M Stark, H Uusi-Kerttula, R Wieneke, R Rahikainen, ... European Journal of Pharmaceutics and Biopharmaceutics 96, 22-31 , 2015 2015 Citations: 69
Mechanical stability of talin rod controls cell migration and substrate sensing. R Rahikainen, M von Essen, M Schaefer, L Qi, L Azizi, C Kelly, ... Scientific reports 7 (1), 3571 , 2017 2017 Citations: 67
Effect of ATP binding and hydrolysis on dynamics of canine parvovirus NS1 EA Niskanen, TO Ihalainen, O Kalliolinna, MM Hakkinen, ... Journal of virology 84 (10), 5391-5403 , 2010 2010 Citations: 58
Regulation of Human Mesenchymal Stem Cell Osteogenesis by Specific Surface Density of Fibronectin: a Gradient Study AB Faia-Torres, T Goren, TO Ihalainen, S Guimond-Lischer, M Charnley, ... ACS applied materials & interfaces 7 (4), 2367-2375 , 2015 2015 Citations: 57
Structural dynamics of tight junctions modulate the properties of the epithelial barrier A Tervonen, TO Ihalainen, S Nymark, J Hyttinen PloS one 14 (4), e0214876 , 2019 2019 Citations: 54
Parvovirus induced alterations in nuclear architecture and dynamics TO Ihalainen, EA Niskanen, J Jylhävä, O Paloheimo, N Dross, ... PLoS One 4 (6), e5948 , 2009 2009 Citations: 52
Nuclear lamina strain states revealed by intermolecular force biosensor BE Danielsson, B George Abraham, E Mäntylä, JI Cabe, CR Mayer, ... Nature Communications 14 (1), 3867 , 2023 2023 Citations: 51
Switchavidin: reversible biotin-avidin-biotin bridges with high affinity and specificity B Taskinen, D Zauner, SI Lehtonen, M Koskinen, C Thomson, ... Bioconjugate Chemistry , 2014 2014 Citations: 51
Direct laser writing of tubular microtowers for 3D culture of human pluripotent stem cell-derived neuronal cells S Turunen, T Joki, ML Hiltunen, TO Ihalainen, S Narkilahti, M Kellomaki ACS applied materials & interfaces 9 (31), 25717-25730 , 2017 2017 Citations: 48
Baculovirus‐mediated immediate‐early gene expression and nuclear reorganization in human cells JP Laakkonen, MU Kaikkonen, PHA Ronkainen, TO Ihalainen, ... Cellular microbiology 10 (3), 667-681 , 2008 2008 Citations: 45
Mitochondrial temperature homeostasis resists external metabolic stresses M Terzioglu, K Veeroja, T Montonen, TO Ihalainen, TS Salminen, P Bénit, ... Elife 12, RP89232 , 2023 2023 Citations: 44
