Dr. Nikunja Kishor Mishra

Dr. Nikunja Kishor Mishra began his career as a research trainee at the R&D division of Natural Remedies Pvt. Ltd., Bangalore. His academic and research journey started in 2008 and has continued at various prestigious pharmacy institutions as Principal/HOD across India. Dr. Mishra has accumulated over 700 Google Scholar citations, with an h-index of 11 and an i10-index of 14. He has successfully guided more than 36 M. Pharm students and has authored 1-text book and 4 book chapters and published 38 research/review papers in various Scopus-indexed journals.
Dr. Mishra has delivered oral presentations at numerous national conferences and serves on the editorial board of 8 scientific journals. In 2022, he was invited as a resource person by the Mahatma Gandhi National Council of Rural Education (MGNCRE), Department of Higher Education, Government of India. He has also been invited to evaluate oral presentations for various organizations. Additionally, Dr. Mishra has organized AICTE-sponsor

EDUCATION

M. Pharm, Ph.D

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacology, Toxicology and Pharmaceutics, Pharmacology (nursing), Pharmacology (medical), Plant Science

FUTURE PROJECTS

Scopus Publications

Childhood obesity and cardiac risk in youth: Emerging challenges toward 2050
Nikunja Kishor Mishra
Clinical Nutrition Espen, 2026
INVESTIGATING THE EFFECTS OF POLYHERBAL GEL ON PHENOL-INDUCED ORAL APHTHOUS ULCERS IN RATS
Nikunja K. Mishra, Uma Mudi, Jyotirmayee Behera, Amiyakanta Mishra, and
Indian Drugs, 2025
Aphthous ulcers, commonly known as canker sores, are among the most widespread oral diseases globally. They typically occur on the non-keratinized mucosal surfaces inside the mouth, including the inner lips, floor of the mouth, and the underside of the tongue. Herbal therapy plays an important role in the healing process of diseases without causing any significant side effects. This study investigates the effects of polyherbal gel (PHG) on phenol-induced oral aphthous ulcers in rats. The rats were randomly assigned to five experimental groups; PHG 5%, 10% and 20% w/V were administered topically to the ulcerated mucosa over a period of seven days respectively. PHG at low, middle and higher dose revealed a significant (P < 0.01) improvement in ulceration healing rate and degree of healing of ulcer area and also diminished the severity of edema and hyperemia located at the ulcer. These findings suggest that PHG may enhance the effectiveness of improving oral aphthous ulceration.
Investigation of the Antidepressant Effect of Paederia foetida L. (Rubiaceae) in Methanolic Extract using a Mice Model
Nikunja Kishor Mishra, Jyotirmayee Behera, Uma Mudi, Amiyakanta Mishra, Ranjan Kumar Jena
Research Journal of Pharmacy and Technology, 2025
Paederia foetida is recognized as ‘skunkvine’ in English, which is having a varied pharmacological importance in therapeutic purpose. Methanolic extract of leaves of P. foetida was administered orally to the swiss albino mice at the doses of 100, 200 and 400mg/kg for 1, 7 or 14 days. All the doses revealed a significant reduction (P ≤ 0.01) in immobility time in a dose-dependent manner compared to the vehicle control group in tail suspension and forced swimming test respectively. A significant increase in locomotor activity (P ≤ 0.01) was observed at all dose levels following oral administration of the extract, compared to the vehicle control group. However, the extract at a dose of 400mg/kg revealed the greatest reduction in immobility time in both the tail suspension and forced swimming tests, as well as an increase in locomotor activity in mice. These results demonstrated that the methanolic extract of P. foetida leaves possesses antidepressant activity.
Current Treatment Process and Challenges for Spinal Muscular Atrophy (SMA)
Nikunja Kishor Mishra, Amiyakanta Mishra, Pravat Kumar Sahoo, Rosy Priyadarshini
Research Journal of Pharmacy and Technology, 2024
Spinal muscular atrophy (SMA) presents as a pediatric neuromuscular disorder resulting from mutations in the survival motor neuron 1(SMN1) gene, with an incidence of approximately 10-13 per 100,000 live births. This condition manifests primarily through muscle weakness and atrophy, particularly affecting the proximal limb muscles. A homozygous deletion of exon 7 in the SMN1 gene is the most common genetic mutation in SMA and serves as a sensitive diagnostic marker. This article comprehensively explores various aspects of SMA, including its types, diagnostic methods, and management strategies. Pulmonary care, gastrointestinal (GI) management, nutritional supplementation, orthopedic spinal care, and physiotherapy play crucial roles in delaying disease progression. Current pharmacological treatments for SMA are diverse and evolving. Notable among them is Zolgensma (formerly AVXS-101 or Onasemnogene abeparvovec), a gene replacement therapy utilizing an adeno-associated virus vector to boost functional SMN protein levels. Sodium vanadate, a phosphatase inhibitor, and risdiplam (RO703406) are agents that modulate SMN2 splicing to augment the production of functional SMN protein. Riluzole acts as a neuroprotective agent by preventing SMN deficiency, while reldesemtive (CK-2127107) is under development as a muscle-enhancing therapy to ameliorate skeletal muscle function during fatigue. While pharmacological therapies for SMA are advancing, a holistic approach involving comprehensive multidisciplinary care, encompassing pulmonary support, proper nutritional supplementation, and adept orthopedic management, significantly contributes to the effective management of SMA.
"Retraction:Microwave mediated organic reaction: A convenient approach for rapid and efficient synthesis of biologically active substituted 1
Jnyanaranjan Panda, Biswa Mohan Sahoo, Nikunja Kishor Mishra, Sai Krushna Padhi, Jitendriya Mishra
Journal of Nanomaterials, 2013
A simple and efficient method has been developed for the synthesis of 1,3-dihydro-2H-indol-2-one derivatives using microwave irradiation technique. By taking advantage of the efficient source of energy of microwave, compound libraries for lead generation and optimization can be assembled in a fraction of time. In the present work, first the Schiff’s bases are synthesized by reaction of isatin with substituted anilines in the presence of acetic acid under microwave heating. Then the condensation of Schiff bases with different secondary amines in the presence of formaldehyde produces Mannich bases. The newly synthesized Mannich bases were characterized by means of spectral data and then evaluated for anthelmintic activity againstPheretima posthuma(Indian earthworm) and compared with standard albendazole. The compounds were evaluated at the concentrations of 10, 20, and 50 mg/mL. The effect of the standard drug albendazole at 10 mg/mL was also evaluated. The results of the present study indicate that some of the test compounds significantly demonstrated paralysis and also caused death of worms in a dose-dependent manner.
Synthesis and screening for antibacterial, analgesic and anti-inflammatory activity of Mannich bases derived from 1H-indole-2,3-dione
Journal of the Indian Chemical Society, 2012
Evaluation of anti-inflammatory activity and potency of herbal formulation consists of different proportions of Curcuma longa and Boswellia Serrata by using cotton pellet granuloma and xylene induced mice ear edema model
International Journal of Pharmtech Research, 2010

RECENT SCHOLAR PUBLICATIONS

Childhood obesity and cardiac risk in youth: Emerging challenges toward 2050
NK Mishra
Clinical Nutrition ESPEN, 103260 , 2026
2026
Citations: 1
Investigation of the Antidepressant Effect of Paederia foetida L.(Rubiaceae) in Methanolic Extract using a Mice Model
NK Mishra, J Behera, U Mudi, A Mishra, RK Jena
Research Journal of Pharmacy and Technology 18 (12), 5850-5854 , 2025
2025
Spinal Muscular Atrophy (SMA): Treatment strategies, challenges and future prospects
NK Mishra, A Mishra
Pharmacological Research-Reports 3, 100031 , 2025
2025
Citations: 7
INVESTIGATING THE EFFECTS OF POLYHERBAL GEL ON PHENOL-INDUCED ORAL APHTHOUS ULCERS IN RATS.
NK Mishra, U Mudi, J Behera, A Mishra
Indian Drugs 62 (2) , 2025
2025
Impact of frontline demonstration on the knowledge and adoption level of farmers during kharif onion production in North Alluvial plains of Bihar
S Ghosh, RK Tiwari, RK Verma, A Biswal, NK Mishra
Journal of Applied Horticulture 26 (2), 248-251 , 2024
2024
Citations: 2
RF conditioning of prototype heavy ion RFQ
RR Sahu, S Goel, NK Mishra, N Mehrotra, SK Mohapatra, PV Gudekar, ...
2024
Citations: 1
Current Treatment Process and Challenges for Spinal Muscular Atrophy (SMA)
NK Mishra, A Mishra, PK Sahoo, R Priyadarshini
Research Journal of Pharmacy and Technology 17 (8), 3730-3738 , 2024
2024
Citations: 1
Reactions in water: synthesis of biologically active compounds
BK Banik, BM Sahoo
Green Approaches in Medicinal Chemistry for Sustainable Drug Design, 157-187 , 2024
2024
Citations: 5
Green chemistry and synthetic approaches in the development of antidepressant and antipsychotic agents
BK Banik, BM Sahoo, B Sahoo, BC Mohanta
Green Approaches in Medicinal Chemistry for Sustainable Drug Design, 513-530 , 2024
2024
Citations: 4
Stock structure analysis of the declining shovel-nosed lobster Thenus unimaculatus (Burton and Davie, 2007) for effective management and conservation along the Indian coast
RD Chakraborty, PT Sarada, G Dash, R Kumar, I Divipala, M Rajkumar, ...
Indian Journal of Fisheries 71 (2), 1-14 , 2024
2024
Synthesis and application of organotellurium compounds
BM Sahoo, BK Banik, A Tiwari, V Tiwari, A Jain, P Borah
Physical Sciences Reviews 8 (12), 4435-4460 , 2023
2023
Citations: 14
Optimized resource allocation in IoT using fuzzy logic and bio-inspired algorithms
DK Sharma, J Mishra, A Singh, R Govil, KK Singh, A Singh
Wireless Personal Communications 131 (2), 1393-1413 , 2023
2023
Citations: 19
Preparation and characterization of gatifloxacin-loaded polyacrylonitrile nanofiber for the management of dry eye infection
DK Sahu, D Pradhan, J Halder, P Biswasroy, B Kar, G Ghosh, G Rath
Journal of Pharmaceutical Innovation 18 (2), 391-403 , 2023
2023
Citations: 8
Non-alcoholic fatty liver disease (NAFLD) and its recent therapeutic strategies
RP Nikunja Kishor Mishra, Amiyakanta Mishra
Research Journal of Pharmacology and Pharmacodynamics 15 (3), 119-126 , 2023
2023
Citations: 2
Exploring the potential of metal nanoparticles as a possible therapeutic adjunct for covid-19 infection
B Kar, D Pradhan, P Mishra, SK Bhuyan, G Ghosh, G Rath
Proceedings of the National Academy of Sciences, India Section B: Biological … , 2022
2022
Citations: 9
Synthetic drives for useful drug molecules through organocatalytic methods
B Krishna Banik, BM Sahoo, A Tiwari, V Tiwari, A Jain, P Borah
Physical Sciences Reviews 7 (4-5), 373-410 , 2022
2022
Citations: 2
Hepatoprotective activity and antioxidant role of hymen-odictyon excelsum bark against paracetamol-induced hepatotoxicity in rats
B Kar, G Ghosh, G Rath, S Bhattacharya
Curr Trends Biotechnol Pharm 16 (2), 203-10 , 2022
2022
Citations: 3
Computational approach to combat COVID-19 infection: emerging tools for accelerating drug research
BM Sahoo, SK Bhattamisra, S Das, A Tiwari, V Tiwari, M Kumar, S Singh
Current Drug Discovery Technologies 19 (3), 40-53 , 2022
2022
Citations: 8
Microwave Irradiated Eco-friendly Synthesis of Pyridine Derivatives as Potential Antitubercular Agents
KC Panda, B Kumar, BS Sahoo, BK Banik, A Tiwari
Asian J. Chem 34 (4), 907-911 , 2022
2022
Citations: 6
Antidiabetic and antihyperlipidemic effects of Premna spinosa bark in experimental animal models
RC Rout, PK Panda, L Behera, SK Panda, G Pattnaik, S Bhattacharya, ...
Journal of Advanced Pharmaceutical Technology & Research 13 (2), 106-110 , 2022
2022
Citations: 3

MOST CITED SCHOLAR PUBLICATIONS

Anti-arthritic activity of Glycyrrhiza glabra, Boswellia serrata and their synergistic activity in combined formulation studied in freund's adjuvant induced arthritic rats
NK Mishra, S Bstia, G Mishra, KA Chowdary, S Patra
Journal of Pharmaceutical Education and Research 2 (2), 92 , 2011
2011
Citations: 101
Anti-arthritic activity of Tribulus terrestris studied in Freund's Adjuvant induced arthritic rats
NK Mishra, GS Biswal, KA Chowdary, G Mishra
Journal of Pharmaceutical Education and Research 4 (1), 41 , 2013
2013
Citations: 37
Influence of hydroxypropyl methylcellulose on drug release pattern of a gastroretentive floating drug delivery system using a 3 2 full factorial design
K Swain, S Pattnaik, S Mallick, KA Chowdary
Pharmaceutical development and technology 14 (2), 193-198 , 2009
2009
Citations: 29
Pharmacological evaluation of Calendula officinalis L. on bronchial asthma in various experimental animals
R Sagar, HH Sahoo, B Kar, NK Mishra, R Mohapatra, SP Sarangi
International journal of nutrition, pharmacology, neurological diseases 4 (2 … , 2014
2014
Citations: 26
Traditional uses and phytopharmacological aspects of Argyreia nervosa
M Padhi, S Mahapatra, J Panda, NK Mishra
Journal of Advanced Pharmaceutical Research 4 (1), 23-32 , 2013
2013
Citations: 25
Optimized resource allocation in IoT using fuzzy logic and bio-inspired algorithms
DK Sharma, J Mishra, A Singh, R Govil, KK Singh, A Singh
Wireless Personal Communications 131 (2), 1393-1413 , 2023
2023
Citations: 19
Synthesis and application of organotellurium compounds
BM Sahoo, BK Banik, A Tiwari, V Tiwari, A Jain, P Borah
Physical Sciences Reviews 8 (12), 4435-4460 , 2023
2023
Citations: 14
Effect of annealing time on the applicability of potato starch as an excipient for the fast disintegrating propranolol hydrochloride tablet
A Gangopadhyay, R Saha, A Bose, RN Sahoo, S Nandi, R Swain, M Paul, ...
Journal of Drug Delivery Science and Technology 67, 103002 , 2022
2022
Citations: 14
Evaluation of antioxidant and antiulcer potentials of Prunus domestica fruit methanolic and extract on Wistar albino rats.
N Mishra, NS Gill, A Mishra, S Mishra, A Shukla, A Upadhayay
2012
Citations: 13
Clinical interventions and budding applications of probiotics in the treatment and prevention of viral infections
D Pradhan, P Biswasroy, B Kar, SK Bhuyan, G Ghosh, G Rath
Archives of Medical Research 53 (2), 122-130 , 2022
2022
Citations: 12
Evaluation of anti-inflammatory activity and potency of herbal formulation consists of different proportions of Curcuma longa and Boswellia serrata by using Cotton …
NK Mishra, JJ Allan
2010
Citations: 12
Renal involvement in bancroftian filariasis.
RN Rath, N Mishra, RN Sahu, G Mohanty, BK Das
The National medical journal of India 4 (2), 65-68 , 1991
1991
Citations: 12
Supercritical Carbon Dioxide Extracts of Cordyceps sinensis : Chromatography-based Metabolite Profiling and Protective Efficacy Against Hypobaric Hypoxia
J Mishra, W Khan, S Ahmad, K Misra
Frontiers in Pharmacology 12, 628924 , 2021
2021
Citations: 11
Effects of oral-dosing of an antiparasitic drug emamectin benzoate on the growth and serum biomarkers of Oreochromis niloticus (L.) juveniles
RB Julinta, TJ Abraham, A Roy, J Singha, G Dash, TK Sar, PK Patil
Journal of Environmental Biology 41 (5), 973-979 , 2020
2020
Citations: 11
Probing collective enhancement in nuclear level density with evaporation particle spectra
G Mohanto, PC Rout, K Ramachandran, K Mahata, ET Mirgule, ...
Physical Review C 105 (3), 034607 , 2022
2022
Citations: 10
Recent trends in nanocarrier based approach in the management of dry eye disease
DK Sahu, D Pradhan, P Biswasroy, B Kar, G Ghosh, G Rath
Journal of Drug Delivery Science and Technology 66, 102868 , 2021
2021
Citations: 10
Histopathology of head kidney tissues in challenged rohu, Labeo rohita Hamilton after vaccinating with Aeromonas hydrophila antigens
A Biswas, G Dash, P Mali, SN Joardar, B Dey, A Roy, S Karmakar
Fish and shellfish immunology reports 2, 100025 , 2021
2021
Citations: 10
Nanotechnology: a novel approach for drug development in health care system
BM Sahoo, BVVR Kumar, CN Patra, JR Panda, BC Mohanta, NN Palei
Current Nanomaterials 5 (1), 12-25 , 2020
2020
Citations: 10
Herbal treatment for common diseases in ruminants: an overview.
DP Mishra, RK Sahu, N Mishra, AK Behera
2015
Citations: 10
Parasitic prevalences in fresh water prawn Macrobrachium rosenbergii in north and south 24 Parganas districts of West Bengal
M Paul, M Chanda, J Maity, S Gupta, B Patra, G Dash
Chronicles of Young Scientists 1 (4), 48-48 , 2010
2010
Citations: 10

Publications

Published a text book: A Textbook of Pathophysiology, LAP- LAMBERT Academic Publishing, German, ISBN: 978-3-659-58013-0 in the month of December-2024.

Published Book-2013 (Polyherbal mixture in Syrup Base: A better Treatment for Arthritis) in International Publisher (LAMBERT ACADEMIC), Germany having ISBN: 978-3-659-36678-9.

Published 38 papers in National and International- Scopus index/ ELSEVIER-Science Direct journals with various impact factors.

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

1. Guided 38 PG Students (Pharmacology) for their research works as part of their M. Pharm curriculum under Biju Patnaik University of Technology, Orissa and Andhra University Visakhapatnam, A.P.
2. Guided more than 84 UG students as part of their graduation under Biju Patnaik University of Technology, Odisha and Andhra University Visakhapatnam, A.P.

CONSULTANCY

1. Editorial and Reviewer Board of the “Journal of Comprehensive and Advanced Pharmacology” on Jan 03, 2017.
2. Prestigious Editorial Board Member of “Journal of Pharmaceutical and Biological Sciences” on Jan 23, 2017.
3. Editorial Board of the “World Journal of Pharmacy and Pharmaceutical sciences” on Feb 18, 2017.
4. Selected as an Advisory Board Member in “World Journal of Pharmaceutical and Life Science” on July 18, 2017.
5. Editorial and Advisory Board Member of “Journal of Bio Innovation” on July 30, 2017.
6. Associate Editor of “Indian Journal of Research in Pharmacy and Biotechnology” on August 02, 2017.
7. Prestigious Editorial Board Mem ber of “Advances in Pharmacology and Therapeutic Medicine” on January 09, 2018.
8. Editorial Board Member of “Indian Journal of Pharmaceutical and Biological Research” on January, 2019.
9. Dr. Nikunja Kishor Mishra, Head of the Department (HOD) of Pharmacology at CPS, Puri has been an active Editorial Board member of Pharmaceutical Sciences & Analytical Research Journal (PSARJ) effective from September 12, 2024.
10. Dr. Mishra also has been appointed as a Review Board Member of Acta Scientific Pharmaceutical Sciences, an international open-access journal, effective from September 26, 2024.
11. Editorial Board Member of Minty Publishers- International Journal of Research in Medical and Health Sciences (IJRMHS) on May 5, 2025.
12. Editorial Board Member of “World Journal of Advance Pharmaceutical Sciences” on May 11, 2025.

Industry, Institute, or Organisation Collaboration

Dr. Nikunja Kishor Mishra was invited as Resource Person by the MGNCRE, Dept. of Higher Education, Govt. of India and was delivered a seminar on the topic “Role of Pharmacist in Social and Community Health Care” on the date 27/02/2022.

INDUSTRY EXPERIENCE

1 year

STARTUP

MSME Business Incubator (BI) Presently working as a Business Incubator under the MSME at CPS, Puri, supporting innovation and entrepreneurship development
To establish an excellence in the field of Higher Education functions with social concern and commitment, integrating modern scientific knowledge.
My students form the core of our existence as an institution, and I want to give wings to their dreams. I expect them to be passionate about their dreams and make their family and society proud of their achievements. It is crucial for the parents to keep reminding their wards to remain focused on their education and to instill in them a sense of responsibility and care towards the concerns of fellow beings. It will give them strength and motivation to work hard for a greater cause in life.
Also to provide the students an educational environment which is second to none, with a strong commitment to impart quality education in the field of research; provide the highest quality education to students, promote intellectual growth and shape their personal development.

SOCIAL, ECONOMIC, or ACADEMIC BENEFITS

National Conference Organized:
• 14 days AICTE sponsored staff development program, 5th-18th July- 2009 at Roland Institute of pharmaceutical sciences, Berhampur, Odisha.
• 12 days AICTE sponsored staff development program, 28th-9th July- 2009 to 2010 at Roland Institute of pharmaceutical sciences, Berhampur, Odisha.
• 11th National IPA Student's Congress, 28th and 29th Feb-2020 at Vignan Institute of Pharmaceutical Technology, Duvvada, Visakhapatnam.