Nailya Bulatova

Scopus Publications

Behind the counter, behind the discourse: The paradox of pharmacist influence in Arabic women's health online
Samar J. Melhem, Hamzeh Almomani, Rimal Mousa, Qais Alefan, Nadia Al Mazrouei, et al.
Exploratory Research in Clinical and Social Pharmacy, 2026
Functional Molecular Plasma Biomarkers of Inflammation and Repair in Kidney Disease Progression in Gum Arabica Modality of CKD
Sameeha AlShelleh, Maysa Suyagh, Hussein Alhawari, Nailya Bulatova, Violet Kasabri, et al.
International Journal of Molecular Sciences, 2026
Using colorimetric ELISA, this study aims to assess the impact of Gum Arabica (GA) consumption on functional molecular plasma biomarkers of chronic kidney disease (CKD) via a prospective cohort of GA-consumers (cases) vs. non-consumer (age- and CKD stage-matched) controls. Cohort’s hypertension (92.5%), dyslipidemia (64.8%), and diabetes mellitus (54.8%) were prevalent; the mean CKD duration was 6.94 years (SD 7.8) for both study groups. Comparable eGFR, sCr, ESR, CRP, HbA1c, FPG, UA, and fasting lipid parameters were in both study arms. In consumer cases, the mean duration of GA-consumption was 1.3 ± 1.1 (range 0.25–6) years with a mean dose of 1.7 ± 1.0 (range 0.5–6) spoons per day. Leucine-rich alpha 2-glycoprotein, plasminogen activator inhibitor 1, sirtuin 1, and SOST–sclerostin 1 were significantly (p value < 0.01) of lower concentrations, but lipocalin 2 and uromodulin were invariably (p value < 0.05) greater in the GA-consumer cases than those of controls. Strikingly, cystatin C, myeloperoxidase, orosomucoid 1, and symmetric dimethylarginine lacked any substantial variations in the GA-consumer cases vs. those in controls (p value > 0.05). Proportional correlations of CKD duration–PAI1 levels and sCr-lipocalin 2 levels but inverse correlations of orosomucoid 1-hypertension duration and SDMA-DBP were evident in cases.
Integrating metabolomics into obesity care: towards biomarker-guided pharmacy practice
Ahmed M Almehdi, Fatima M Al Daffaie, Basma M Sharaf, Adnane Guella, Nelson C Soares, et al.
Pharmacy Practice, 2026
Enhancing Clinical Decision-Making in Gestational Diabetes Through Metabolomics: A Pharmacy Practice Outlook
Pharmacy Practice, 2026
Combinatorial multiplicity of cardiometabolic and inflammatory markers in gum arabica modality of CKD CAM: Part 2
Sameeha Alshelleh, Maysa Suyagh, Hussein Alhawari, NAILYA BULATOVA, VIOLET KASABRI, et al.
Pharmacy Practice, 2025
Scaling holistic e-health solutions in cancer care using a qualitative realist framework
Samar J. Melhem, Shereen Nabhani-Gebara, Nailya Bulatova, Ibrahim Alabbadi, Hamzeh Almomani, et al.
Frontiers in Public Health, 2025
Background While e-health innovations have advanced cancer-care delivery in high-income countries, middle-income countries (MICs) face distinct systemic, infrastructural, and sociocultural challenges in adopting and scaling digital-health interventions. There is a growing imperative to explore how holistic digital platforms can be implemented effectively in oncology within resource-constrained settings. Objective This study aimed to investigate the barriers and facilitators influencing the scalability and adoption of a comprehensive e-health solution in cancer care, drawing on a realist paradigm to determine what works, for whom, and under which circumstances, in the context of Jordan. Methods A qualitative study, underpinned by a realist paradigm, was conducted using in-depth, semi-structured interviews with oncology healthcare professionals from diverse clinical settings in Jordan. Interviews were conducted in Arabic, translated into English, and analyzed using a hybrid inductive–deductive framework approach. The Implementation of Change Model guided interpretation of the findings, enabling the identification of multi-level contextual influences. Results The analysis yielded a central theme— Facilitators and Barriers to Implementing a Holistic e-health Solution —comprising six deductive subthemes derived from the Implementation of Change Model: (A) Innovation; (B) Patients; (C) Healthcare professionals; (D) Organizational context; (E) Social context; and (F) Economic and political context. Across these subthemes, interpretive codes were classified as barriers or facilitators. Participants emphasized the necessity of assessing e-health readiness prior to implementation, and the importance of integrated, cross-sectoral approaches to support scalable, sustainable solutions. Conclusion This study provides novel, contextually grounded insights into the implementation dynamics of digital transformation in oncology within MICs. It offers actionable guidance for policymakers and system designers aiming to foster sustainable, equitable digital-health ecosystems.
The relationship of selected biomarkers of gut microbiota dysbiosis with adiposity and metabolic risk factors in nascent metabolic syndrome patients
Pharmacy Practice, 2024
Correlation of Plasma and Salivary Osteocalcin Levels with Nascent Metabolic Syndrome Components with and Without Pre/Diabetes Biochemical Parameters
Pharmacy Practice, 2024
Differential changes in maternal proinflammatory IL6 plasma levels as a putatively surrogate marker of candidacy and clinical utility during mid-and late pregnancy hyperglycemia: interventional impact of clinical pharmacist on maternal and neonatal outcomes in a randomized clinical trial
Pharmacy Practice, 2024
Results of Preclinical Studies of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazole-4-th Bromide in Relation to the Hemostasis System in vivo
Y. Wang, N. R. Bulatova, E. E. Klen, G. A. Rozit, I. L. Nikitina, et al.
Drug Development and Registration, 2024
Introduction. A characteristic manifestation of vascular brain damage is depressive disorders that accompany both acute and chronic disorders of cerebral circulation. Depression not only reduces the patient's quality of life, but also complicates the treatment of basic vascular disease, increases the risk of stroke and death. Therefore, complex therapy of vascular depression includes not only antidepressants, but also basic means to correct the consequences of disorders of cerebral blood flow, including with antiplatelet activity. In this regard, the development of a new molecule based on thietane-containing heterocycles, combining the properties of an antidepressant and an antiplatelet agent.Aim. To conduct a preclinical evaluation of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazol-4 bromide when administered to rats.Materials and methods. A study was conducted of the effect of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietan-3-yl)-1H-1,2,4-triazol-4-bromide on the hemostasis system during intravenous and intragastric administration to healthy white non-linear sexually mature male rats (n = 160). Thromboelastography was performed on a TEG 5000 device, activated with a 0.2 M solution of calcium chloride, Born aggregometry and standard clotting tests to assess the coagulation component of hemostasis.Result and discussion. The findings show that 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazole-4-th bromide with peroral administration exceeded acetylsalicylic acid by 2.8 times in terms of ED50, and by 1.8 times with intravenous way of administration accordingly. A similar effect of pentoxifylline in the intravenous route of administration was recorded at a concentration of 27.8 mg/kg versus 12.4 mg/kg of compound I. The results of a complex method to assess the state of the hemostasis system indicate a more pronounced antiaggregational effect of compound I compared with pentoxifylline and acetylsalicylic acid.Conclusion. Preclinical studies of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazole-4 bromide, was demonstrated that a combination of antidepressant and antiplatelet activity, which can serve as a basis for further drug development.
Alteration in the expression of the chemotherapy resistance-related genes in response to chronic and acute hypoxia in pancreatic cancer
Malek Zihlif, Tareq Hameduh, Nailya Bulatova, Hana Hammad
Biomedical Reports, 2023
Plasma carnitine, choline, γ-butyrobetaine, and trimethylamine-N-oxide, but not zonulin, are reduced in overweight/obese patients with pre/diabetes or impaired glycemia
Alia Snouper, Violet Kasabri, Nailya Bulatova, Maysa Suyagh, Monther Sadder, et al.
International Journal of Diabetes in Developing Countries, 2023
A Cross-sectional Study of the Catalase Genetic Polymorphism (-262 cytosine/ thymine) and Blood Catalase Activity among Jordanian Vitiligo Patients
Ebtesam Alhawamdeh, Nailya R. Bulatova, Al Motassem F. Yousef, Mohammed A. AlAbbadi, Ethar A. Omer
Jordan Journal of Pharmaceutical Sciences, 2023
The Effect of Antipsychotics and Their Combinations with Other Psychotropic Drugs on Electrocardiogram Intervals Other Than QTc among Jordanian Adult Outpatients
Nailya Bulatova, Noor Altaher, Radwan BaniMustafa, Akram Al-Saleh, Haya Yasin, et al.
Biomedicines, 2023
Use of traditional and complementary medicine for COVID 19 prophylaxis among healthcare professionals and students in Jordan: A cross-sectional study
Nailya Bulatova, Sara Younes, Majd Arabiyat, Ahmad Abukaff, Sara Madanat, et al.
Plos One, 2022
Serotonin reuptake inhibitors effect on fluconazole activity against resistant Candida glabrata strains
Bashar A. Alkhalifa, Nailya R. Bulatova, Waed abuRokba, Rula M. Darwish
Journal of Global Antimicrobial Resistance, 2022
Identification of Insulin Resistance Biomarkers in Metabolic Syndrome Detected by UHPLC-ESI-QTOF-MS
Leen Oyoun Alsoud, Nelson C. Soares, Hamza M. Al-Hroub, Muath Mousa, Violet Kasabri, et al.
Metabolites, 2022
Painful subacute thyroiditis occurring after the administration of influenza vaccine and hyaluronic acid dermal filler
Nailya R. Bulatova, Ayman A. Zayed, Ula Qasem Hijjawi, Satani G. Sharkas, Faris G. Bakri
Medicine United States, 2022
Silver nanoparticles, a promising treatment against clinically important fluconazole-resistant Candida glabrata
R.M. Darwish, M.Y. AlKawareek, N.R. Bulatova, A.M. Alkilany
Letters in Applied Microbiology, 2021
Characterization of staphylococci sampled from diabetic foot ulcer of Jordanian patients
A.G. Al‐Bakri, N.R. Bulatova, N.A. Younes, G. Othman, D. Jaber, et al.
Journal of Applied Microbiology, 2021
Pharmaceutical Care in the Treatment of Substance Use Disorders in Jordan: A Randomized Controlled Trial
Haya Yasin, Nailya Bulatova, Mayyada Wazaify
Substance Use and Misuse, 2021
The effect of psychotropic medications and their combinations on the QTC interval among jordanian outpatients: A cross-sectional study
Nailya Bulatova, Noor Altaher, Radwan A. BaniMustafa, Akram Al-Saleh, Haya Yasin, et al.
Anadolu Psikiyatri Dergisi, 2021
Patterns of Substance Use among Patients in Addiction Rehabilitation in Jordan.
Haya Yasin, Nailya Bulatova, Mayyada Wazaify
Substance Use and Misuse, 2020
Patterns and perceived efficacy of herbal medicine for weight loss and maintenance: A cross-sectional survey from Jordan
Amal Akour, Violet Kasabri, Nailya Bulatova, Suha Al Muhaissen, Ruba Al Tarawneh, et al.
European Journal of Integrative Medicine, 2020
A pre-post study of vitamin d supplement effects on urinary megalin: The emerging predictive role of megalin in diabetic nephropathy progression
Violet Kasabri, Amal Akour, Nailya Bulatova, Maysa Suyagh, Al Motassem Yousef, et al.
Endocrine Metabolic and Immune Disorders Drug Targets, 2020

RECENT SCHOLAR PUBLICATIONS

Integrating metabolomics into obesity care: towards biomarker guided pharmacy practice
AM Almehdi, FM Al-Daffaie, BM Sharaf, A Guella, NC Soares, ...
Pharmacy Practice 24 (1), 1-17 , 2026
2026
Behind the counter, behind the discourse: The paradox of pharmacist influence in Arabic women's health online
SJ Melhem, H Almomani, R Mousa, Q Alefan, N Al Mazrouei, ...
Exploratory Research in Clinical and Social Pharmacy 21, 100697 , 2026
2026
Citations: 1
Functional Molecular Plasma Biomarkers of Inflammation and Repair in Kidney Disease Progression in Gum Arabica Modality of CKD
S AlShelleh, M Suyagh, H Alhawari, N Bulatova, V Kasabri, A Wahbeh, ...
International Journal of Molecular Sciences 27 (2), 973 , 2026
2026
Enhancing Clinical Decision-Making in Gestational Diabetes Through Metabolomics: A Pharmacy Practice Outlook
RT Tokatly, BM Sharaf, AY Abuhelwa, SF Soliman, W El-Huneidi, ...
Pharmacy Practice (Granada) 24 (1), 9 , 2026
2026
Scaling holistic e-health solutions in cancer care using a qualitative realist framework
SJ Melhem, S Nabhani-Gebara, N Bulatova, I Alabbadi, H Almomani, ...
Frontiers in Public Health 13, 1617857 , 2025
2025
Citations: 1
Combinatorial multiplicity of cardiometabolic and inflammatory markers in gum arabica modality of CKD CAM: Part 2
S Alshelleh, M Suyagh, H Alhawari, N Bulatova, V Kasabri, A Wahbeh, ...
Pharmacy Practice 23 (3), 1-17 , 2025
2025
The relationship of selected biomarkers of gut microbiota dysbiosis with adiposity and metabolic risk factors in nascent metabolic syndrome patients
M Suyagh, V Kasabri, N Bulatova, S AbuLoha, J Al Bzour, R AlQuoqa
Pharmacy Practice (Granada) 22 (3), 24 , 2024
2024
Correlation of plasma and salivary osteocalcin levels with nascent metabolic syndrome components with and without pre/diabetes biochemical parameters
N Bulatova, VN Kasabri, AM Albsoul, L Halaseh, M Suyagh
Pharmacy Practice (Granada) 22 (1), 2 , 2024
2024
Citations: 2
Differential changes in maternal proinflammatory IL6 plasma levels as a putatively surrogate marker of candidacy and clinical utility during mid-and late pregnancy …
A Albsoul, N Bulatova, V Kasabri, R AlQuoqa, N Khawaja, D Hyassat, ...
Pharmacy Practice (Granada) 22 (1), 3 , 2024
2024
Alteration in the expression of the chemotherapy resistance‑related genes in response to chronic and acute hypoxia in pancreatic cancer
M Zihlif, T Hameduh, N Bulatova, H Hammad
Biomedical Reports 19 (6), 88 , 2023
2023
Citations: 7
Plasma carnitine, choline, γ-butyrobetaine, and trimethylamine-N-oxide, but not zonulin, are reduced in overweight/obese patients with pre/diabetes or impaired glycemia
A Snouper, V Kasabri, N Bulatova, M Suyagh, M Sadder, K Shnewer, ...
International Journal of Diabetes in Developing Countries 43 (4), 592-605 , 2023
2023
Citations: 4
A Cross-sectional Study of the Catalase Genetic Polymorphism (-262 cytosine/thymine) and Blood Catalase Activity among Jordanian Vitiligo Patients.
EH Alhawmdeh, NR Bulatova, AMF Yousef, MA AlAbbadi, EA Omer
Jordan Journal of Pharmaceutical Sciences 16 (2) , 2023
2023
Citations: 5
The Clinical Utility of salivary oxytocin as a putatively surrogate early Risk Identification biomarker of nascent Metabolic Syndrome with and without prediabetes
NR Bulatova, VN Kasabri, AM Albsoul, L Halaseh, M Suyagh
2023
The effect of antipsychotics and their combinations with other psychotropic drugs on electrocardiogram intervals other than QTc among Jordanian adult outpatients
N Bulatova, N Altaher, R BaniMustafa, A Al-Saleh, H Yasin, M Zawiah, ...
Biomedicines 11 (1), 13 , 2022
2022
Citations: 6
Use of traditional and complementary medicine for COVID 19 prophylaxis among healthcare professionals and students in Jordan: A cross-sectional study
N Bulatova, S Younes, M Arabiyat, A Abukaff, S Madanat, E Alqudah, ...
Plos one 17 (10), e0276015 , 2022
2022
Citations: 18
Identification of insulin resistance biomarkers in metabolic syndrome detected by UHPLC-ESI-QTOF-MS
LO Alsoud, NC Soares, HM Al-Hroub, M Mousa, V Kasabri, N Bulatova, ...
Metabolites 12 (6), 508 , 2022
2022
Citations: 29
Serotonin reuptake inhibitors effect on fluconazole activity against resistant Candida glabrata strains
BA Alkhalifa, NR Bulatova, RM Darwish
Journal of Global Antimicrobial Resistance 29, 49-54 , 2022
2022
Citations: 16
Painful subacute thyroiditis occurring after the administration of influenza vaccine and hyaluronic acid dermal filler: a case report
NR Bulatova, AA Zayed, UQ Hijjawi, SG Sharkas, FG Bakri
Medicine 101 (11), e29120 , 2022
2022
Citations: 7
School of Pharmacy
NR Bulatova
The University of Jordan , 2022
2022
Silver nanoparticles, a promising treatment against clinically important fluconazole‐resistant Candida glabrata
RM Darwish, MY AlKawareek, NR Bulatova, AM Alkilany
Letters in Applied Microbiology 73 (6), 718-724 , 2021
2021
Citations: 5

MOST CITED SCHOLAR PUBLICATIONS

Validation of a comprehensive classification tool for treatment-related problems
SM AbuRuz, NR Bulatova, AM Yousef
Pharmacy World and Science 28 (4), 222-232 , 2006
2006
Citations: 122
The validity and reliability of the Arabic version of the EQ-5D: a study from Jordan
S Aburuz, N Bulatova, M Twalbeh, M Gazawi
Annals of Saudi medicine 29 (4), 304-308 , 2009
2009
Citations: 111
Comprehensive assessment of treatment related problems in hospitalized medicine patients in Jordan
SM AbuRuz, NR Bulatova, AMM Yousef, MA Al-Ghazawi, IA Alawwa, ...
International journal of clinical pharmacy 33 (3), 501-511 , 2011
2011
Citations: 91
The use of medicinal herbs in gynecological and pregnancy-related disorders by Jordanian women: a review of folkloric practice vs. evidence-based pharmacology
A Akour, V Kasabri, FU Afifi, N Bulatova
Pharmaceutical biology 54 (9), 1901-1918 , 2016
2016
Citations: 78
Allele and genotype frequencies of the polymorphic cytochrome P450 genes ( CYP1A1 , CYP3A4, CYP3A5, CYP2C9 and CYP2C19 ) in the Jordanian population
AM Yousef, NR Bulatova, W Newman, N Hakooz, S Ismail, H Qusa, ...
Molecular biology reports 39 (10), 9423-9433 , 2012
2012
Citations: 73
Associations between patient factors and medication adherence: a Jordanian experience
IA Basheti, SS El Hait, EA Qunaibi, S Aburuz, N Bulatova
Pharmacy Practice (Granada) 14 (1), 0-0 , 2016
2016
Citations: 66
Smoking behaviour modulates pharmacokinetics of orally administered clopidogrel
AM Yousef, T Arafat, NR Bulatova, R Al‐Zumyli
Journal of clinical pharmacy and therapeutics 33 (4), 439-449 , 2008
2008
Citations: 64
Home medication management review in outpatients with chronic diseases in Jordan: a randomized control trial
IA Basheti, RA Al-Qudah, NM Obeidat, NR Bulatova
International journal of clinical pharmacy 38 (2), 404-413 , 2016
2016
Citations: 59
Treatment related problems for outpatients with chronic diseases in Jordan: the value of home medication reviews
IA Basheti, EA Qunaibi, NR Bulatova, S Samara, S AbuRuz
International journal of clinical pharmacy 35 (1), 92-100 , 2013
2013
Citations: 57
Skin prick test reactivity to aeroallergens in Jordanian allergic rhinitis patients
S Aburuz, N Bulatova, M Tawalbeh
East Mediterr Health J 17 (7), 604-610 , 2011
2011
Citations: 51
Adverse effects of tacrolimus in renal transplant patients from living donors
N Bulatova, AM Yousef, G Al-Khayyat, H Qosa
Current drug safety 6 (1), 3-11 , 2011
2011
Citations: 41
Patient perspectives of the role of the community pharmacist in the Middle East: Jordan, United Arab Emirates and Iraq
IA Basheti, EA Qunaibi, SA Hamadi, E Abu-Gharbieh, S Saleh, S AbuRuz, ...
Pharmacology & Pharmacy 5 (06), 588-599 , 2014
2014
Citations: 37
Association of oxytocin with glucose intolerance and inflammation biomarkers in metabolic syndrome patients with and without prediabetes
A Akour, V Kasabri, N Bulatova, S Al Muhaissen, R Naffa, H Fahmawi, ...
The Review of Diabetic Studies: RDS 14 (4), 364 , 2018
2018
Citations: 34
Stroke awareness in the general population: a study from Jordan
SS Madae’en, NR Bulatova, A Al-Qhewii, LH Sakran, HH El-Zayyat, ...
Tropical Journal of Pharmaceutical Research 12 (6), 1071-1076 , 2013
2013
Citations: 33
The correlation between plasma levels of oxytocin and betatrophin in non-diabetic and diabetic metabolic syndrome patients: A cross sectional study from Jordan
A Al-Rawashdeh, V Kasabri, N Bulatova, A Akour, A Zayed, M Momani, ...
Diabetes & Metabolic Syndrome: Clinical Research & Reviews 11 (1), 59-67 , 2017
2017
Citations: 32
Knowledge, attitude and opinion of drug misuse and abuse by pharmacy students: A cross-sectional study in Jordan
D Jaber, N Bulatova, M Suyagh, AM Yousef, M Wazaify
Tropical journal of pharmaceutical research 14 (8), 1501-1508 , 2015
2015
Citations: 30
Identification of insulin resistance biomarkers in metabolic syndrome detected by UHPLC-ESI-QTOF-MS
LO Alsoud, NC Soares, HM Al-Hroub, M Mousa, V Kasabri, N Bulatova, ...
Metabolites 12 (6), 508 , 2022
2022
Citations: 29
Patterns of Substance Use among Patients in Addiction Rehabilitation in Jordan.
H Yasin, N Bulatova, M Wazaify
Substance use & misuse 55 (7), 1035-1044 , 2020
2020
Citations: 29
Glycated LDL-C and glycated HDL-C in association with adiposity, blood and atherogenicity indices in metabolic syndrome patients with and without prediabetes
RM Al Saudi, V Kasabri, R Naffa, N Bulatova, Y Bustanji
Therapeutic advances in endocrinology and metabolism 9 (10), 311-323 , 2018
2018
Citations: 29
Influence of genotype and haplotype of MDR1 (C3435T, G2677A/T, C1236T) on the incidence of breast cancer-a case-control study in Jordan
KZ Majdalawi
Asian pacific journal of cancer prevention , 2016
2016
Citations: 28

Nailya Bulatova

EDUCATION

RESEARCH INTERESTS

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS