Ki-Taek Lim

@bioroboticseng.com

Department of Biosystems Engineering/Professor
Kangwon National University



                 

https://researchid.co/ktlim74

RESEARCH, TEACHING, or OTHER INTERESTS

Multidisciplinary, Agricultural and Biological Sciences

177

Scopus Publications

5306

Scholar Citations

42

Scholar h-index

106

Scholar i10-index

Scopus Publications

  • NIR-activated catechol-functionalized nanodiamond nanofibers for accelerating on-demand MRSA and E. coli biofilm eradication
    Hyeonseo Park, Tejal V. Patil, Jieun Lee, Hojin Kim, Seong-Jun Cho, and Ki-Taek Lim
    Springer Science and Business Media LLC
    Abstract The rise of antibiotic resistance has made bacterial infections a persistent global health issue. In particular, extracellular polymeric substances (EPS) secreted by bacteria limit the effectiveness of conventional antibiotics, making biofilm removal challenging. To address this, we created ND@PDA nanoparticles by coating the surface of nanodiamonds (ND) with polydopamine (PDA). These nanoparticles were then integrated into polyvinyl alcohol to fabricate PVA/ND@PDA nanofiber scaffolds, resulting in an innovative platform with enhanced photothermal, antibacterial and antibiofilm properties. Upon exposure to near-infrared (NIR) light, the scaffolds exhibited a significant photothermal activity, oxidative stress and effectively damaging key bacterial components, such as biofilm, bacterial membranes, and proteins. Additionally, the catechol groups in PDA provided strong cell adhesion and high biocompatibility on the nanofiber surface. Our research proposes a platform that not only effectively addresses antibiotic-resistant infections but also contributes to advancements in wound healing therapies by enabling controlled antibacterial action with minimal toxicity.

  • Tailoring osteoimmunity and hemostasis using 3D-Printed nano-photocatalytic bactericidal scaffold for augmented bone regeneration
    Sayan Deb Dutta, Jin Hexiu, Md Moniruzzaman, Tejal V. Patil, Rumi Acharya, Jong Sung Kim, and Ki-Taek Lim
    Elsevier BV

  • 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
    Sayan Deb Dutta, Jeong Man An, Jin Hexiu, Aayushi Randhawa, Keya Ganguly, Tejal V. Patil, Thavasyappan Thambi, Jangho Kim, Yong-kyu Lee, and Ki-Taek Lim
    Elsevier BV

  • Physical stimuli-responsive 3D printable hydrogels for scalable manufacturing of bioengineered meat analogs
    Jieun Lee, Sayan Deb Dutta, Tejal V. Patil, Seong-Jun Cho, and Ki-Taek Lim
    Elsevier BV

  • Electroconductive Nanocellulose, a Versatile Hydrogel Platform: From Preparation to Biomedical Engineering Applications
    Myoung Joon Jeon, Aayushi Randhawa, Hojin Kim, Sayan Deb Dutta, Keya Ganguly, Tejal V. Patil, Jieun Lee, Rumi Acharya, Hyeonseo Park, Youjin Seol,et al.
    Wiley
    AbstractNanocelluloses have garnered significant attention recently in the attempt to create sustainable, improved functional materials. Nanocellulose possesses wide varieties, including rod‐shaped crystalline cellulose nanocrystals and elongated cellulose nanofibers, also known as microfibrillated cellulose. In recent times, nanocellulose has sparked research into a wide range of biomedical applications, which vary from developing 3D printed hydrogel to preparing structures with tunable characteristics. Owing to its multifunctional properties, different categories of nanocellulose, such as cellulose nanocrystals, cellulose nanofibers, and bacterial nanocellulose, as well as their unique properties are discussed here. Here, different methods of nanocellulose‐based hydrogel preparation are covered, which include 3D printing and crosslinking methods. Subsequently, advanced nanocellulose‐hydrogels addressing conductivity, shape memory, adhesion, and structural color are highlighted. Finally, the application of nanocellulose‐based hydrogel in biomedical applications is explored here. In summary, numerous perspectives on novel approaches based on nanocellulose‐based research are presented here.

  • In Vitro Osteogenic Response to Copper-Doped Eggshell-Derived Hyroxyapatite With Macrophage Supplements
    Tejal V. Patil, Dinesh K. Patel, and Ki‐Taek Lim
    Wiley
    ABSTRACTThe high bioactivity and biocompatibility of hydroxyapatite (HAP) make it a useful bone graft material for bone tissue engineering. However, the development superior osteoconductive and osteoinductive materials for bone regeneration remains a challenge. To overcome these constraints, Cu‐doped hydroxyapatite (HAP(Cu)) from waste eggshells has been produced for bone tissue engineering. The materials produced were characterized using Fourier transform infrared spectroscopy, x‐ray diffraction, and photoelectron spectroscopy. The scanning microscopy images revealed that the developed HAP was a rod‐like crystalline structure with a typical 80–150 nm diameter. Energy‐dispersive x‐ray spectroscopy showed that the generated HAP was mostly composed of calcium, oxygen, and phosphorus. The Ca/P molar ratios in eggshell‐derived and copper‐doped HAP were 1.61 and 1.67, respectively, similar to the commercially available HAP ratio (1.67). The WST‐8 assay was used to assess the biocompatibility of HAPs with hBMSCs. HAP(Cu) in the media significantly altered the cytotoxicity of biocompatible HAP(Cu). The osteogenic potential of HAP(Cu) was demonstrated by greater mineralization than that of pure HAP or the control. HAP(Cu) showed higher osteogenic gene expression than pure HAP and the control, indicating its stronger osteogenic potential. Furthermore, we assessed the effects of sample‐treated macrophage‐derived conditioned medium (CM) on hBMSCs' osteogenesis. CM‐treated HAP(Cu) demonstrated a significantly higher osteogenic potential vis‐à‐vis pure HAP(Cu). These findings revealed that HAP(Cu) with CM significantly improved osteogenesis in hBMSCs and can be explored as a bone graft in bone tissue engineering.


  • Zn@TA assisted dual cross-linked 3D printable glycol grafted chitosan hydrogels for robust antibiofilm and wound healing
    Tejal V. Patil, Hexiu Jin, Sayan Deb Dutta, Rumi Aacharya, Kehan Chen, Keya Ganguly, Aayushi Randhawa, and Ki-Taek Lim
    Elsevier BV

  • Single-Walled Carbon Nanotube-Based Optical Nano/Biosensors for Biomedical Applications: Role in Bioimaging, Disease Diagnosis, and Biomarkers Detection
    Rumi Acharya, Tejal V. Patil, Sayan Deb Dutta, Jieun Lee, Keya Ganguly, Hojin Kim, Aayushi Randhawa, and Ki‐Taek Lim
    Wiley
    AbstractThe convergence of advanced nanotechnology with disease diagnosis has ushered in a transformative era in healthcare, empowering early and accurate detection of diseases and paving the way for timely interventions, improved treatment outcomes, and enhanced patient well‐being. The development of novel materials is frequently the impetus behind significant advancements in sensor technology. Among them, single‐walled carbon nanotubes (SWCNTSs) have emerged as promising nanomaterials for developing biosensors. Their unique optical, electrical, and biocompatibility properties make them promising candidates for enhancing the sensitivity and real‐time monitoring capabilities of biosensors, as well as for enabling various bioimaging techniques. Recent studies have demonstrated the utility of SWCNTS‐based biosensors in the real‐time monitoring of biological analytes, such as nitric oxide and hydrogen peroxide (H2O2), with potential implications for disease understanding and therapeutic response assessment. Moreover, SWCNTSs have shown promise in bioimaging applications, including fluorescence, Raman spectroscopy, and photoluminescence imaging of biological samples. This article delves into the core principles, design strategies, and operational mechanisms that underpin SWCNTS‐bioimaging techniques‐based biosensors. It emphasizes on their unique properties and versatile functionalization of carbon nanotubes, laying the foundation for their integration into biosensor platforms and applications aimed at diagnosing a wide spectrum of diseases including infectious diseases, cancer, neurological disorders, and metabolic conditions.


  • Stimuli-Mediated Macrophage Switching, Unraveling the Dynamics at the Nanoplatforms–Macrophage Interface
    Keya Ganguly, Rachmi Luthfikasari, Aayushi Randhawa, Sayan Deb Dutta, Tejal V. Patil, Rumi Acharya, and Ki‐Taek Lim
    Wiley
    AbstractMacrophages play an essential role in immunotherapy and tissue regeneration owing to their remarkable plasticity and diverse functions. Recent bioengineering developments have focused on using external physical stimuli such as electric and magnetic fields, temperature, and compressive stress, among others, on micro/nanostructures to induce macrophage polarization, thereby increasing their therapeutic potential. However, it is difficult to find a concise review of the interaction between physical stimuli, advanced micro/nanostructures, and macrophage polarization. This review examines the present research on physical stimuli‐induced macrophage polarization on micro/nanoplatforms, emphasizing the synergistic role of fabricated structure and stimulation for advanced immunotherapy and tissue regeneration. A concise overview of the research advancements investigating the impact of physical stimuli, including electric fields, magnetic fields, compressive forces, fluid shear stress, photothermal stimuli, and multiple stimulations on the polarization of macrophages within complex engineered structures, is provided. The prospective implications of these strategies in regenerative medicine and immunotherapeutic approaches are highlighted. This review will aid in creating stimuli‐responsive platforms for immunomodulation and tissue regeneration.

  • Stimuli-triggered pollen-inspired micro/nanorobots for advanced therapeutics
    Youjin Seol, Keya Ganguly, Hojin Kim, Aayushi Randhawa, Tejal V. Patil, Sayan Deb Dutta, Rumi Acharya, and Ki-Taek Lim
    Elsevier BV

  • Manufacturing 3D Biomimetic Tissue: A Strategy Involving the Integration of Electrospun Nanofibers with a 3D-Printed Framework for Enhanced Tissue Regeneration
    Aayushi Randhawa, Sayan Deb Dutta, Keya Ganguly, Tejal V. Patil, and Ki‐Taek Lim
    Wiley
    Abstract3D printing and electrospinning are versatile techniques employed to produce 3D structures, such as scaffolds and ultrathin fibers, facilitating the creation of a cellular microenvironment in vitro. These two approaches operate on distinct working principles and utilize different polymeric materials to generate the desired structure. This review provides an extensive overview of these techniques and their potential roles in biomedical applications. Despite their potential role in fabricating complex structures, each technique has its own limitations. Electrospun fibers may have ambiguous geometry, while 3D‐printed constructs may exhibit poor resolution with limited mechanical complexity. Consequently, the integration of electrospinning and 3D‐printing methods may be explored to maximize the benefits and overcome the individual limitations of these techniques. This review highlights recent advancements in combined techniques for generating structures with controlled porosities on the micro–nano scale, leading to improved mechanical structural integrity. Collectively, these techniques also allow the fabrication of nature‐inspired structures, contributing to a paradigm shift in research and technology. Finally, the review concludes by examining the advantages, disadvantages, and future outlooks of existing technologies in addressing challenges and exploring potential opportunities.

  • PAI-1 transfected-conditioned media promotes osteogenic differentiation of hBMSCs
    Zhang Li, Hou Kegui, Wang Piao, Wang Xuejiu, Ki‐Taek Lim, and Hexiu Jin
    Wiley
    AbstractReconstruction of injured bone remains challenging in the clinic owing to the lack of suitable bone grafts. The utilization of PAI‐1 transfected‐conditioned media (P‐CM) has demonstrated its ability to facilitate the differentiation process of mesenchymal stem cells (MSCs), potentially serving as a crucial mediator in tissue regeneration. This research endeavored to explore the therapeutic potential of P‐CM concerning the differentiation of human bone marrow mesenchymal stem cells (hBMSCs). To assess new bone formation, a rat calvaria critical defect model was employed, while in vitro experiments involved the use of the alizarin Red‐S mineral induction test. In the rat calvaria critical defect model, P‐CM treatment resulted in significan new bone formation. In vitro, P‐CM treated hBMSCs displayed robust osteogenesis compared to the control group, as demonstrated by the mineral induction test using alizarin Red‐S. P‐CM with hydroxyapatite/β‐tricalcium phosphate/fibrin gel treatment significantly exhibited new bone formation, and the expression of osteogenic associated markers was enhanced in the P‐CM‐treated group. In conclusion, results demonstrate that P‐CM treatment significantly enhanced the osteogenic differantiation efficiency and new bone formation, thus could be used as an ideal therapeutic biomolecule for constructing bone‐specific implants, especially for orthopedic and dental applications.

  • Sunflower Pollen-Morphology Mimicked Spiky Zinc Nanomotors as a Photosensitizer for Killing Bacteria and Cancer Cells
    Sayan Deb Dutta, Rachmi Luthfikasari, Tejal V. Patil, Keya Ganguly, Youjin Seol, Aayushi Randhawa, and Ki-Taek Lim
    American Chemical Society (ACS)
    Photosensitizing agents have received increased attention from the medical community, owing to their higher photothermal efficiency, induction of hyperthermia, and sustained delivery of bioactive molecules to their targets. Micro/nanorobots can be used as ideal photosensitizing agents by utilizing various physical stimuli for the targeted killing of pathogens (e.g., bacteria) and cancer cells. Herein, we report sunflower-pollen-inspired spiky zinc oxide (s-ZnO)-based nanorobots that effectively kill bacteria and cancer cells under near-infrared (NIR) light irradiation. The as-fabricated s-ZnO was modified with a catechol-containing photothermal agent, polydopamine (PDA), to improve its NIR-responsive properties, followed by the addition of antimicrobial (e.g., tetracycline/TCN) and anticancer (e.g., doxorubicin/DOX) drugs. The fabricated s-ZnO/PDA@Drug nanobots exhibited unique locomotory behavior with an average speed ranging from 13 to 14 μm/s under 2.0 W/cm2 NIR light irradiation. Moreover, the s-ZnO/PDA@TCN nanobots exhibited superior antibacterial activity against E. coli and S. epidermidis under NIR irradiation. The s-ZnO/PDA@DOX nanobots also displayed sufficient reactive oxygen species (ROS) amplification in B16F10 melanoma cells and induced apoptosis under NIR light, indicating their therapeutic efficacy. We hope the sunflower pollen-inspired s-ZnO nanorobots have tremendous potential in biomedical engineering from the phototherapy perspective, with the hope to reduce pathogen infections.

  • Extracellular Matrix-Bioinspired Anisotropic Topographical Cues of Electrospun Nanofibers: A Strategy of Wound Healing through Macrophage Polarization
    Hyeonseo Park, Tejal V. Patil, Sayan Deb Dutta, Jieun Lee, Keya Ganguly, Aayushi Randhawa, Hojin Kim, and Ki‐Taek Lim
    Wiley
    AbstractThe skin serves as the body's outermost barrier and is the largest organ, providing protection not only to the body but also to various internal organs. Owing to continuous exposure to various external factors, it is susceptible to damage that can range from simple to severe, including serious types of wounds such as burns or chronic wounds. Macrophages play a crucial role in the entire wound healing process and contribute significantly to skin regeneration. Initially, M1 macrophages infiltrate to phagocytose bacteria, debris, and dead cells in fresh wounds. As tissue repair is activated, M2 macrophages are promoted, reducing inflammation and facilitating restoration of the dermis and epidermis to regenerate the tissue. Based on this understanding, developing extracellular matrix (ECM) mimicking structures is suitable for promoting cell attachment, proliferation, migration, and macrophage polarization. Among the numerous strategies, electrospinning is a versatile technique for obtaining ECM‐mimicking structures with anisotropic and isotropic topologies of micro/nanofibers. The use of various biomaterials in the fabrication of nanofibers with anisotropic and isotropic topologies can influence macrophage polarization. Moreover, these fibers possess a high surface‐area‐to‐volume ratio, promoting the effective exchange of vital nutrients and oxygen, which are crucial for cell viability and tissue regeneration. Micro/nanofibers with diverse physical and chemical properties can be tailored to polarize macrophages toward skin regeneration and wound healing, depending on specific requirements. This review describes the significance of micro/nano structures for activating macrophages and promoting wound healing.This article is protected by copyright. All rights reserved

  • Assessment of the biocompatibility and bioimaging potential of fluorescent carbon dots derived from waste biomass
    Dinesh K. Patel, So-Yeon Won, Eunseo Jung, Sayan Deb Dutta, Tejal V. Patil, Ki-Taek Lim, and Sung Soo Han
    Elsevier BV

  • Unzipped carbon nanotubes assisted 3D printable functionalized chitosan hydrogels for strain sensing applications
    Dinesh K. Patel, So-Yeon Won, Tejal V. Patil, Sayan Deb Dutta, Ki-Taek Lim, and Sung Soo Han
    Elsevier BV

  • Recent advances and biomedical application of 3D printed nanocellulose-based adhesive hydrogels: A review
    Hojin Kim, Sayan Deb Dutta, Aayushi Randhawa, Tejal V. Patil, Keya Ganguly, Rumi Acharya, Jieun Lee, Hyeonseo Park, and Ki-Taek Lim
    Elsevier BV

  • 3D Printable Hydrogel Bioelectronic Interfaces for Healthcare Monitoring and Disease Diagnosis: Materials, Design Strategies, and Applications
    Sayan Deb Dutta, Keya Ganguly, Aayushi Randhawa, Tejal V. Patil, Hojin Kim, Rumi Acharya, and Ki‐Taek Lim
    Wiley
    AbstractIn recent years, additive manufacturing tools, such as 3D printing, has gained enormous attention in biomedical engineering for developing ionotropic devices, flexible electronics, skin‐electronic interfaces, and wearable sensors with extremely high precision and sensing accuracy. Such printed bioelectronics are innovative and can be used as multi‐stimuli response platforms for human health monitoring and disease diagnosis. This review systematically discusses the past, present, and future of the various printable and stretchable soft bioelectronics for precision medicine. The potential of various naturally and chemically derived conductive biopolymer inks and their nanocomposites with tunable physico‐chemical properties is also highlighted, which is crucial for bioelectronics fabrication. Then, the design strategies of various printable sensors for human body sensing are summarized. In conclusion, the perspectives on the future advanced bioelectronics are described, which will be helpful, particularly in the field of nano/biomedicine. An in‐depth knowledge of materials design to functional aspects of printable bioelectronics is demonstrated, with an aim to accelerate the development of next‐generation wearables.

  • Stimuli-Responsive 3D Printable Conductive Hydrogel: A Step toward Regulating Macrophage Polarization and Wound Healing
    Jieun Lee, Sayan Deb Dutta, Rumi Acharya, Hyeonseo Park, Hojin Kim, Aayushi Randhawa, Tejal V. Patil, Keya Ganguly, Rachmi Luthfikasari, and Ki‐Taek Lim
    Wiley
    AbstractConductive hydrogels (CHs) are promising alternatives for electrical stimulation of cells and tissues in biomedical engineering. Wound healing and immunomodulation are complex processes that involve multiple cell types and signaling pathways. 3D printable conductive hydrogels have emerged as an innovative approach to promote wound healing and modulate immune responses. CHs can facilitate electrical and mechanical stimuli, which can be beneficial for altering cellular metabolism and enhancing the efficiency of the delivery of therapeutic molecules. This review summarizes the recent advances in 3D printable conductive hydrogels for wound healing and their effect on macrophage polarization. This report also discusses the properties of various conductive materials that can be used to fabricate hydrogels to stimulate immune responses. Furthermore, this review highlights the challenges and limitations of using 3D printable CHs for future material discovery. Overall, 3D printable conductive hydrogels hold excellent potential for accelerating wound healing and immune responses, which can lead to the development of new therapeutic strategies for skin and immune‐related diseases.

  • Size-Wise Effect of Agricultural By-Product-Derived Calcium Phosphate Composites on Stem Cell Osteogenesis
    Kyoung-Je Jang, Sangbae Park, Juo Lee, Yeonggeol Hong, Hoon Seonwoo, Ki-Taek Lim, Jangho Kim, and Jong Hoon Chung
    Springer Science and Business Media LLC

  • Trackable and highly fluorescent nanocellulose-based printable bio-resins for image-guided tissue regeneration
    Sayan Deb Dutta, Tejal V. Patil, Keya Ganguly, Aayushi Randhawa, Rumi Acharya, Md Moniruzzaman, and Ki-Taek Lim
    Elsevier BV

  • A Review on Electroactive Polymer–Metal Composites: Development and Applications for Tissue Regeneration
    Rumi Acharya, Sayan Deb Dutta, Tejal V. Patil, Keya Ganguly, Aayushi Randhawa, and Ki-Taek Lim
    MDPI AG
    Electroactive polymer–metal composites (EAPMCs) have gained significant attention in tissue engineering owing to their exceptional mechanical and electrical properties. EAPMCs develop by combining an electroactive polymer matrix and a conductive metal. The design considerations include choosing an appropriate metal that provides mechanical strength and electrical conductivity and selecting an electroactive polymer that displays biocompatibility and electrical responsiveness. Interface engineering and surface modification techniques are also crucial for enhancing the adhesion and biocompatibility of composites. The potential of EAPMC-based tissue engineering revolves around its ability to promote cellular responses, such as cell adhesion, proliferation, and differentiation, through electrical stimulation. The electrical properties of these composites can be used to mimic natural electrical signals within tissues and organs, thereby aiding tissue regeneration. Furthermore, the mechanical characteristics of the metallic components provide structural reinforcement and can be modified to align with the distinct demands of various tissues. EAPMCs have extraordinary potential as regenerative biomaterials owing to their ability to promote beneficial effects in numerous electrically responsive cells. This study emphasizes the characteristics and applications of EAPMCs in tissue engineering.


RECENT SCHOLAR PUBLICATIONS

  • Tailoring osteoimmunity and hemostasis using 3D-Printed nano-photocatalytic bactericidal scaffold for augmented bone regeneration
    SD Dutta, J Hexiu, M Moniruzzaman, TV Patil, R Acharya, JS Kim, KT Lim
    Biomaterials 316, 122991 2025

  • 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
    SD Dutta, JM An, J Hexiu, A Randhawa, K Ganguly, TV Patil, T Thambi, ...
    Bioactive Materials 45, 345-362 2025

  • NIR-activated catechol-functionalized nanodiamond nanofibers for accelerating on-demand MRSA and E. coli biofilm eradication
    H Park, TV Patil, J Lee, H Kim, SJ Cho, KT Lim
    Journal of Biological Engineering 19 (1), 2 2025

  • Physical stimuli-responsive 3D printable hydrogels for scalable manufacturing of bioengineered meat analogs
    J Lee, SD Dutta, TV Patil, SJ Cho, KT Lim
    Trends in Food Science & Technology, 104867 2025

  • Electroconductive Nanocellulose, a Versatile Hydrogel Platform: From Preparation to Biomedical Engineering Applications
    MJ Jeon, A Randhawa, H Kim, SD Dutta, K Ganguly, TV Patil, J Lee, ...
    Advanced Healthcare Materials 14 (3), 2403983 2025

  • In Vitro Osteogenic Response to Copper‐Doped Eggshell‐Derived Hyroxyapatite With Macrophage Supplements
    TV Patil, DK Patel, KT Lim
    Journal of Biomedical Materials Research Part A 113 (1), e37838 2025

  • Transcriptomic profiling of human mesenchymal stem cells using a pulsed electromagnetic-wave motion bioreactor system for enhanced osteogenic commitment and therapeutic potentials
    A Randhawa, K Ganguly, SD Dutta, TV Patil, KT Lim
    Biomaterials 312, 122713 2025

  • Zn@ TA assisted dual cross-linked 3D printable glycol grafted chitosan hydrogels for robust antibiofilm and wound healing
    TV Patil, H Jin, SD Dutta, R Aacharya, K Chen, K Ganguly, A Randhawa, ...
    Carbohydrate Polymers 344, 122522 2024

  • Single‐Walled Carbon Nanotube‐Based Optical Nano/Biosensors for Biomedical Applications: Role in Bioimaging, Disease Diagnosis, and Biomarkers Detection
    R Acharya, TV Patil, SD Dutta, J Lee, K Ganguly, H Kim, A Randhawa, ...
    Advanced Materials Technologies 9 (20), 2400279 2024

  • NIR-responsive carbon dots as an oxidative-stress amplifier and hyperthermia-induced superior photothermal in-vitro anticancer activity
    M Moniruzzaman, SD Dutta, R Acharya, KT Lim, J Kim
    Colloids and Surfaces A: Physicochemical and Engineering Aspects 696, 134266 2024

  • Stimuli-triggered pollen-inspired micro/nanorobots for advanced therapeutics
    Y Seol, K Ganguly, H Kim, A Randhawa, TV Patil, SD Dutta, R Acharya, ...
    Nano Today 57, 102337 2024

  • Stimuli‐Mediated Macrophage Switching, Unraveling the Dynamics at the Nanoplatforms–Macrophage Interface
    K Ganguly, R Luthfikasari, A Randhawa, SD Dutta, TV Patil, R Acharya, ...
    Advanced Healthcare Materials 13 (20), 2400581 2024

  • 3D Printed Multifunctional Bioadhesive Patch with Intrinsic Bioelectronic Properties for Decoding Electromechanical and Anisotropic Cardiac Microenvironment
    SD Dutta, TV Patil, KT Lim
    bioRxiv, 2024.07. 05.601338 2024

  • PAI‐1 transfected‐conditioned media promotes osteogenic differentiation of hBMSCs
    Z Li, H Kegui, W Piao, W Xuejiu, KT Lim, H Jin
    Cell Biology International 48 (7), 997-1006 2024

  • Manufacturing 3D Biomimetic Tissue: A Strategy Involving the Integration of Electrospun Nanofibers with a 3D‐Printed Framework for Enhanced Tissue Regeneration
    A Randhawa, SD Dutta, K Ganguly, TV Patil, KT Lim
    Small 20 (27), 2309269 2024

  • Sunflower Pollen-Morphology Mimicked Spiky Zinc Nanomotors as a Photosensitizer for Killing Bacteria and Cancer Cells
    SD Dutta, R Luthfikasari, TV Patil, K Ganguly, Y Seol, A Randhawa, ...
    ACS Applied Bio Materials 7 (6), 3731-3745 2024

  • Extracellular Matrix‐Bioinspired Anisotropic Topographical Cues of Electrospun Nanofibers: A Strategy of Wound Healing through Macrophage Polarization
    H Park, TV Patil, SD Dutta, J Lee, K Ganguly, A Randhawa, H Kim, KT Lim
    Advanced Healthcare Materials 13 (12), 2304114 2024

  • Unzipped carbon nanotubes assisted 3D printable functionalized chitosan hydrogels for strain sensing applications
    DK Patel, SY Won, TV Patil, SD Dutta, KT Lim, SS Han
    International Journal of Biological Macromolecules 265, 131025 2024

  • Recent advances and biomedical application of 3D printed nanocellulose-based adhesive hydrogels: A review
    H Kim, SD Dutta, A Randhawa, TV Patil, K Ganguly, R Acharya, J Lee, ...
    International Journal of Biological Macromolecules, 130732 2024

  • 3D Printable Hydrogel Bioelectronic Interfaces for Healthcare Monitoring and Disease Diagnosis: Materials, Design Strategies, and Applications
    SD Dutta, K Ganguly, A Randhawa, TV Patil, H Kim, R Acharya, KT Lim
    Advanced Materials Technologies 9 (6), 2301874 2024

MOST CITED SCHOLAR PUBLICATIONS

  • Functional cellulose-based hydrogels as extracellular matrices for tissue engineering
    SD Dutta, DK Patel, KT Lim
    Journal of Biological Engineering 13 (1), 55 2019
    Citations: 211

  • Bioactive effects of graphene oxide cell culture substratum on structure and function of human adipose‐derived stem cells
    J Kim, KS Choi, Y Kim, KT Lim, H Seonwoo, Y Park, DH Kim, PH Choung, ...
    Journal of Biomedical Materials Research Part A: An Official Journal of The 2013
    Citations: 197

  • Graphene-incorporated chitosan substrata for adhesion and differentiation of human mesenchymal stem cells
    J Kim, YR Kim, Y Kim, KT Lim, H Seonwoo, S Park, SP Cho, BH Hong, ...
    Journal of Materials Chemistry B 1 (7), 933-938 2013
    Citations: 197

  • 3D-printed bioactive and biodegradable hydrogel scaffolds of alginate/gelatin/cellulose nanocrystals for tissue engineering
    SD Dutta, J Hexiu, DK Patel, K Ganguly, KT Lim
    International Journal of Biological Macromolecules 167, 644-658 2021
    Citations: 185

  • Nanocellulose, a versatile platform: From the delivery of active molecules to tissue engineering applications
    TV Patil, DK Patel, SD Dutta, K Ganguly, TS Santra, KT Lim
    Bioactive materials 9, 566-589 2022
    Citations: 179

  • Eggshell membrane: Review and impact on engineering
    S Park, KS Choi, D Lee, D Kim, KT Lim, KH Lee, H Seonwoo, J Kim
    Biosystems engineering 151, 446-463 2016
    Citations: 163

  • Designing nanotopographical density of extracellular matrix for controlled morphology and function of human mesenchymal stem cells
    J Kim, HN Kim, KT Lim, Y Kim, H Seonwoo, SH Park, HJ Lim, DH Kim, ...
    Scientific reports 3 (1), 3552 2013
    Citations: 151

  • Nanocellulose-based polymer hybrids and their emerging applications in biomedical engineering and water purification
    DK Patel, SD Dutta, KT Lim
    RSC advances 9 (33), 19143-19162 2019
    Citations: 129

  • Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells
    J Kim, HN Kim, KT Lim, Y Kim, S Pandey, P Garg, YH Choung, ...
    Biomaterials 34 (30), 7257-7268 2013
    Citations: 129

  • Carbon nanotubes-based nanomaterials and their agricultural and biotechnological applications
    DK Patel, HB Kim, SD Dutta, K Ganguly, KT Lim
    Materials 13 (7), 1679 2020
    Citations: 118

  • Bioactive electrospun nanocomposite scaffolds of poly (lactic acid)/cellulose nanocrystals for bone tissue engineering
    DK Patel, SD Dutta, J Hexiu, K Ganguly, KT Lim
    International Journal of Biological Macromolecules 162, 1429-1441 2020
    Citations: 105

  • Multiscale patterned transplantable stem cell patches for bone tissue regeneration
    J Kim, WG Bae, HW Choung, KT Lim, H Seonwoo, HE Jeong, KY Suh, ...
    Biomaterials 35 (33), 9058-9067 2014
    Citations: 98

  • In Vitro Effects of Low‐Intensity Pulsed Ultrasound Stimulation on the Osteogenic Differentiation of Human Alveolar Bone‐Derived Mesenchymal Stem Cells for
    KT Lim, J Kim, H Seonwoo, SH Park, PH Choung, JH Chung
    BioMed research international 2013 (1), 269724 2013
    Citations: 93

  • Bacterial cellulose nanofibrillar patch as a wound healing platform of tympanic membrane perforation
    J Kim, SW Kim, S Park, KT Lim, H Seonwoo, Y Kim, BH Hong, YH Choung, ...
    Advanced healthcare materials 2 (11), 1525-1531 2013
    Citations: 83

  • 3D-printable chitosan/silk fibroin/cellulose nanoparticle scaffolds for bone regeneration via M2 macrophage polarization
    DK Patel, SD Dutta, J Hexiu, K Ganguly, KT Lim
    Carbohydrate Polymers 281, 119077 2022
    Citations: 82

  • Effects of electromagnetic fields on osteogenesis of human alveolar bone‐derived mesenchymal stem cells
    KT Lim, J Hexiu, J Kim, H Seonwoo, WJ Cho, PH Choung, JH Chung
    BioMed research international 2013 (1), 296019 2013
    Citations: 80

  • Monolayer graphene-directed growth and neuronal differentiation of mesenchymal stem cells
    J Kim, S Park, YJ Kim, CS Jeon, KT Lim, H Seonwoo, SP Cho, TD Chung, ...
    Journal of biomedical nanotechnology 11 (11), 2024-2033 2015
    Citations: 77

  • A review of properties of nanocellulose, its synthesis, and potential in biomedical applications
    A Randhawa, SD Dutta, K Ganguly, TV Patil, DK Patel, KT Lim
    Applied Sciences 12 (14), 7090 2022
    Citations: 76

  • Fabrication and characterization of 3D printable nanocellulose-based hydrogels for tissue engineering
    DK Patel, SD Dutta, WC Shin, K Ganguly, KT Lim
    RSC advances 11 (13), 7466-7478 2021
    Citations: 74

  • Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing
    DK Patel, K Ganguly, J Hexiu, SD Dutta, TV Patil, KT Lim
    Carbohydrate Polymers 284, 119202 2022
    Citations: 72