Lazaro Hiram Betancourt Nunez

@med.lu.se

Associate Researcher, Department of Translational Medicine,Skåne University Hospital Malmö
Lund University

Lazaro Hiram Betancourt Nunez


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https://researchid.co/lazarohiram

RESEARCH, TEACHING, or OTHER INTERESTS

Cancer Research, Molecular Medicine, Multidisciplinary, Biotechnology
2113

Scholar Citations

28

Scholar h-index

47

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Distant metastases of melanoma exhibit varying extent of intrapatient proteogenomic heterogeneity
    B Szeitz, YP Hagemeijer, ZG Pahi, Z Ujfaludi, M Kuras, J Rodriguez, ...
    Clinical and Translational Medicine 15 (10), e70477 , 2025
    2025
    Citations: 2
  • The melanoma MEGA-study: Integrating proteogenomics, digital pathology, and AI-analytics for precision oncology
    J Guedes, L Szadai, N Woldmar, ÁJ Jánosi, K Koroncziová, BM Lengyel, ...
    Journal of proteomics 319, 105482 , 2025
    2025
    Citations: 3
  • Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies
    Y Kim, V Doma, U Çakır, M Kuras, LH Betancourt, I Pla, A Sanchez, ...
    Cancer 131 (13), e35897 , 2025
    2025
    Citations: 8
  • Melanoma proteomics unveiled: harmonizing diverse data sets for biomarker discovery and clinical insights via MEL-PLOT
    Á Bartha, B Weltz, LH Betancourt, J Gil, N Pinto de Almeida, G Bianchini, ...
    Journal of Proteome Research 24 (6), 3117-3128 , 2025
    2025
    Citations: 3
  • Unbiased drug target prediction reveals sensitivity to ferroptosis inducers, HDAC and RTK inhibitors in melanoma subtypes
    I Pla, BL Szabolcs, PN Péter, Z Ujfaludi, Y Kim, P Horvatovich, A Sanchez, ...
    International journal of dermatology 64 (5), 870-881 , 2025
    2025
    Citations: 4
  • Proteogenomic profiling of treatment-naïve metastatic malignant melanoma
    M Kuras, LH Betancourt, R Hong, L Szadai, J Rodriguez, P Horvatovich, ...
    Cancers 17 (5), 832 , 2025
    2025
    Citations: 5
  • In Vivo Photopolymerization: Achieving Detailed Conducting Patterns for Bioelectronics
    F Ek, T Abrahamsson, M Savvakis, S Bormann, AH Mousa, MA Shameem, ...
    Advanced Science 11 (48), 2408628 , 2024
    2024
    Citations: 5
  • Proteogenomics reveals varying levels of intra-patient heterogeneity in melanoma metastases
    B Szeitz, Y Hagemeijer, Z Pahi, Z Ujfaludi, V Doma, J Gil, R Appelqvist, ...
    VIRCHOWS ARCHIV 485, S430-S430 , 2024
    2024
  • Predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts
    L Szadai, A Bartha, IP Parada, AIT Lakatos, DMP Pál, AS Lengyel, ...
    Frontiers in Oncology 14, 1428182 , 2024
    2024
    Citations: 6
  • Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma
    NP de Almeida, AJ Janosi, R Hong, A Rajeh, F Nogueira, L Szadai, ...
    CLINICAL AND TRANSLATIONAL MEDICINE 14 (7) , 2024
    2024
  • Mitochondrial dysfunction and immune suppression in BRAF V600E‐mutated metastatic melanoma
    N Pinto de Almeida, ÁJ Jánosi, R Hong, A Rajeh, F Nogueira, L Szadai, ...
    Clinical and Translational Medicine 14 (7), e1773 , 2024
    2024
    Citations: 5
  • Identifying Ferroptosis Inducers, HDAC, and RTK Inhibitor Sensitivity in Melanoma Subtypes through Unbiased Drug Target Prediction
    I Pla, BL Szabolcs, PN Péter, Z Ujfaludi, Y Kim, P Horvatovich, A Sanchez, ...
    bioRxiv, 2024.02. 08.579424 , 2024
    2024
  • A time-efficient workflow to purify a library of alanine mutants of surface-exposed residues of the domain III of the envelope protein of dengue virus serotype 1.
    MD AM, LG González-Lodeiro, C González, L Betancourt
    Micropublication Biology 2023 , 2023
    2023
    Citations: 2
  • A time-efficient workflow to purify a library of alanine mutants of surface-exposed residues of the domain III of the envelope protein of dengue virus serotype 1
    DM Prieto, AMM Dunn, AE Llumbet, LG González-Lodeiro, MS Núñez, ...
    MicroPublication Biology 2023, 10.17912/micropub. biology. 001012 , 2023
    2023
    Citations: 1
  • Histopathology-assisted proteogenomics provides foundations for stratification of melanoma metastases
    M Kuras, LH Betancourt, R Hong, L Szadai, J Rodriguez, P Horvatovich, ...
    BioRxiv, 2023.09. 29.559755 , 2023
    2023
    Citations: 3
  • Proteogenomic Characterization Reveals Therapeutic Opportunities Related to Mitochondrial Function in Melanoma
    J Gil, Y Kim, V Doma, U Çakır, M Kuras, LH Betancourt, IP Parada, ...
    BioRxiv, 2022.10. 24.513481 , 2022
    2022
    Citations: 3
  • Method Matters: Exploring Alkoxysulfonate-Functionalized Poly(3,4-ethylenedioxythiophene) and Its Unintentional Self-Aggregating Copolymer toward Injectable Bioelectronics
    RO Abdelrazek H Mousa, David Bliman, Lazaro Hiram Betancourt, Karin Hellman ...
    Chem Mater. 34 (6), 2752-2763 , 2022
    2022
    Citations: 25
  • Mapping the melanoma plasma proteome (MPP) using single-shot proteomics interfaced with the WiMT database
    N Almeida, J Rodriguez, I Pla Parada, Y Perez-Riverol, N Woldmar, Y Kim, ...
    Cancers 13 (24), 6224 , 2021
    2021
    Citations: 8
  • Deep proteomic analysis on biobanked paraffine-archived melanoma with prognostic/predictive biomarker read-out
    L Szadai, E Velasquez, B Szeitz, NP Almeida, G Domont, LH Betancourt, ...
    Cancers 13 (23), 6105 , 2021
    2021
    Citations: 13
  • A biobanking turning‐point in the use of formalin‐fixed, paraffin tumor blocks to unveil kinase signaling in melanoma
    E Velasquez, L Szadai, Q Zhou, Y Kim, I Pla, A Sanchez, R Appelqvist, ...
    Clinical and Translational Medicine 11 (8), e466 , 2021
    2021
    Citations: 13

MOST CITED SCHOLAR PUBLICATIONS

  • Activation of Rho through a cross‐link with polyamines catalyzed by Bordetella dermonecrotizing toxin
    M Masuda, L Betancourt, T Matsuzawa, T Kashimoto, T Takao, ...
    The EMBO Journal 19 (4), 521-530 , 2000
    2000
    Citations: 142
  • CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
    SE Perea, O Reyes, I Baladron, Y Perera, H Farina, J Gil, A Rodriguez, ...
    Molecular and cellular biochemistry 316 (1), 163-167 , 2008
    2008
    Citations: 141
  • Primary structure of two cytolysin isoforms from Stichodactyla helianthus differing in their hemolytic activity.
    V Huerta, V Morera, Y Guanche, G Chinea, LJ González, L Betancourt, ...
    Toxicon 39 (8), 1253-1256 , 2001
    2001
    Citations: 99
  • Differentiating α‐and β‐aspartic acids by electrospray ionization and low‐energy tandem mass spectrometry
    LJ González, T Shimizu, Y Satomi, L Betancourt, V Besada, G Padrón, ...
    Rapid Communications in Mass Spectrometry 14 (22), 2092-2102 , 2000
    2000
    Citations: 97
  • Automated interpretation of low‐energy collision‐induced dissociation spectra by SeqMS, a software aid for de novo sequencing by tandem mass spectrometry
    J Fernandez‐de‐Cossio, J Gonzalez, Y Satomi, T Shima, N Okumura, ...
    ELECTROPHORESIS: An International Journal 21 (9), 1694-1699 , 2000
    2000
    Citations: 94
  • Outer membrane vesicles of the VA‐MENGOC‐BC® vaccine against serogroup B of Neisseria meningitidis : Analysis of protein components by two‐dimensional …
    L Uli, L Castellanos‐Serra, L Betancourt, F Domínguez, R Barberá, ...
    Proteomics 6 (11), 3389-3399 , 2006
    2006
    Citations: 89
  • A novel fusion protein domain III-capsid from dengue-2, in a highly aggregated form, induces a functional immune response and protection in mice
    I Valdés, L Bernardo, L Gil, A Pavón, L Lazo, C López, Y Romero, ...
    Virology 394 (2), 249-258 , 2009
    2009
    Citations: 80
  • Automated interpretation of high‐energy collision‐induced dissociation spectra of singly protonated peptides by ‘seqms', a software aid for de novo sequencing by …
    J Fernandez‐de‐Cossio, J Gonzalez, L Betancourt, V Besada, G Padron, ...
    Rapid communications in mass spectrometry 12 (23), 1867-1878 , 1998
    1998
    Citations: 72
  • Quantitative assessment of urea in-solution Lys-C/trypsin digestions reveals superior performance at room temperature over traditional proteolysis at 37 C
    LH Betancourt, A Sanchez, I Pla, M Kuras, Q Zhou, R Andersson, ...
    Journal of proteome research 17 (7), 2556-2561 , 2018
    2018
    Citations: 63
  • Proteome analysis of Leishmania (Viannia) braziliensis by two-dimensional gel electrophoresis and mass spectrometry
    P Cuervo, JB de Jesus, M Junqueira, L Mendonça-Lima, LJ González, ...
    Molecular and biochemical parasitology 154 (1), 6-21 , 2007
    2007
    Citations: 59
  • CIGB-300, a synthetic peptide-based drug that targets the CK2 phosphoaceptor domain. Translational and clinical research
    SE Perea, I Baladron, Y Garcia, Y Perera, A Lopez, JL Soriano, N Batista, ...
    Molecular and cellular biochemistry 356 (1), 45-50 , 2011
    2011
    Citations: 58
  • Automated interpretation of mass spectra of complex mixtures by matching of isotope peak distributions
    J Fernández‐de‐Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, ...
    Rapid Communications in Mass Spectrometry 18 (20), 2465-2472 , 2004
    2004
    Citations: 49
  • Isoelectric point optimization using peptide descriptors and support vector machines
    Y Perez-Riverol, E Audain, A Millan, Y Ramos, A Sanchez, JA Vizcaíno, ...
    Journal of proteomics 75 (7), 2269-2274 , 2012
    2012
    Citations: 48
  • Identification of vimentin as a potential therapeutic target against HIV infection
    C Fernández-Ortega, A Ramírez, D Casillas, T Paneque, R Ubieta, ...
    Viruses 8 (6), 98 , 2016
    2016
    Citations: 47
  • Clinical protein science in translational medicine targeting malignant melanoma
    J Gil, LH Betancourt, I Pla, A Sanchez, R Appelqvist, T Miliotis, M Kuras, ...
    Cell biology and toxicology 35 (4), 293-332 , 2019
    2019
    Citations: 44
  • Isotopica: a tool for the calculation and viewing of complex isotopic envelopes
    J Fernandez-de-Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, ...
    Nucleic acids research 32 (suppl_2), W674-W678 , 2004
    2004
    Citations: 43
  • The human melanoma proteome atlas—complementing the melanoma transcriptome
    LH Betancourt, J Gil, A Sanchez, V Doma, M Kuras, JR Murillo, ...
    Clinical and Translational Medicine 11 (7), e451 , 2021
    2021
    Citations: 41
  • In silico analysis of accurate proteomics, complemented by selective isolation of peptides
    Y Perez-Riverol, A Sánchez, Y Ramos, A Schmidt, M Müller, L Betancourt, ...
    Journal of proteomics 74 (10), 2071-2082 , 2011
    2011
    Citations: 40
  • Levansucrase from Acetobacter diazotrophicus SRT4 Is Secreted via Periplasm by a Signal-Peptide-Dependent Pathway
    L Hernández, J Arrieta, L Betancourt, V Falcón, J Madrazo, A Coego, ...
    Current microbiology 39 (3), 146-152 , 1999
    1999
    Citations: 39
  • Assessing automated sample preparation technologies for high-throughput proteomics of frozen well characterized tissues from Swedish biobanks
    M Kuras, LH Betancourt, M Rezeli, J Rodriguez, M Szasz, Q Zhou, ...
    Journal of Proteome Research 18 (1), 548-556 , 2018
    2018
    Citations: 37