stephane avril

Verified email at emse.fr

Biomedical Engineering / SAINBIOSE
Mines Saint-Etienne



                                         

https://researchid.co/stephaneavril

2021-2022: Guest Professor, Technische Universität Graz, Austria.

2020-2022: Guest Professor, Technische Universität Wien, Austria.

2014- 2019: Visiting Professor, Yale University, USA.

EDUCATION

2007: Habilitation à Diriger les Recherches, Université de Technologie de Compiègne, France.

2002: PhD with honors in mechanical and civil engineering, Ecole Nationale Supérieure des Mines, Saint-Etienne, France.

1999: Engineering Graduate School, Ecole Nationale Supérieure des Mines, Saint-Étienne, France.

1999: MSc with honors in mechanical and civil engineering, University of Clermont-Ferrand, France.

1998: Bachelor in mathematics, University of Saint-Etienne, France.

RESEARCH INTERESTS

1. Map quantitatively and non-invasively, with a microscopic resolution, the local mechanical properties (stiffness, resistance, tensile and shear stresses) in the extracellular matrix of biological tissues.
2. Computer modelling for assisting cardiovascular surgical interventions
3. Computer modell

FUTURE PROJECTS

MecOnChip

Recent vascular engineering efforts have focused on two distinct directions: either tissue engineered vessels for implantation as grafts or engineered vascular mimics (vessels-on-a-chip) that serve as platforms for understanding vascular development and disease or for testing the effects of drugs and/or endovascular devices. Our proposal falls in the second category. The state of the art is typically the production of a system that mimics the physiological setting to the extent possible by targeting relevant dimensions, incorporating the pertinent cell types, and attempting to reproduce physiological conditions. Our aim is to go at least one step further and to design and develop a vessel-on-a-chip platform that allows control of the cellular response by modulating the local mechanical environment. Our research hypothesis is that the cross-talk between cells and their biophysical microenvironment regulates the phenotypic endpoint of each single cell.


Applications Invited
6013

Scholar Citations

42

Scholar h-index

98

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • FEniCS implementation of the Virtual Fields Method (VFM) for nonhomogeneous hyperelastic identification
    J Deng, X Guo, Y Mei, S Avril
    Advances in Engineering Software 175, 103343 2023

  • Towards the 2D velocity reconstruction in abdominal aorta from Color-Doppler Ultrasound
    MN Antonuccio, HG Morales, A This, K Capellini, S Avril, S Celi, L Rouet
    Medical Engineering & Physics 107, 103873 2022

  • EndoBeams. jl: A Julia finite element package for beam-to-surface contact problems in cardiovascular mechanics
    B Bisighini, M Aguirre, B Pierrat, D Perrin, S Avril
    Advances in Engineering Software 171, 103173 2022

  • Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms: A Systematic Review and Discussion of the Clinical Potential
    A Mourato, R Valente, J Xavier, M Brito, S Avril, JC de S, A Toms, ...
    Applied Sciences 12 (16), 8049 2022

  • Evolving Mural Defects, Dilatation, and Biomechanical Dysfunction in Angiotensin II–Induced Thoracic Aortopathies
    D Weiss, AS Long, G Tellides, S Avril, JD Humphrey, MR Bersi
    Arteriosclerosis, Thrombosis, and Vascular Biology 42 (8), 973-986 2022

  • Evaluation of image registration for measuring deformation fields in soft tissue mechanics
    O Lisick, S Avril, B Eydan, B Pierrat, J Burša
    Strain 58 (4), e12424 2022

  • Atomic Force Microscopy Stiffness Mapping in Human Aortic Smooth Muscle Cells
    C Petit, AA Karkhaneh Yousefi, M Guilbot, V Barnier, S Avril
    Journal of Biomechanical Engineering 144 (8), 081001 2022

  • Parameters CFD Analyses Influencing of Different the Hemodynamic Outcomes of Complex Aortic Endovascular Repair
    C FAVRE, E ROSSET, F CONDEMI, S AVRIL
    Biological Flow in Large Vessels: Dialog Between Numerical Modeling and In 2022

  • CFD Analyses of Different Parameters Influencing the Hemodynamic Outcomes of Complex Aortic Endovascular Repair
    S Ben‐Ahmed, JN Albertini, JP Favre, CA Figueroa, E Rosset, F Condemi, ...
    Biological Flow in Large Vessels: Dialog Between Numerical Modeling and In 2022

  • Fluid–Structure Interaction Modeling of Ascending Thoracic Aortic Aneurysms in SimVascular
    R Valente, A Mourato, M Brito, J Xavier, A Toms, S Avril
    Biomechanics 2 (2), 189-204 2022

  • Computer Simulation Model May Prevent Thoracic Stent-Graft Collapse Complication
    L Derycke, S Avril, D Perrin, JN Albertini, F Cochennec
    Circulation: Cardiovascular Imaging 15 (4), e013764 2022

  • About prestretch in homogenized constrained mixture models simulating growth and remodeling in patient-specific aortic geometries
    JD Laubrie, SJ Mousavi, S Avril
    Biomechanics and modeling in mechanobiology 21 (2), 455-469 2022

  • Material identification on thin shells using the virtual fields method, demonstrated on the human eardrum
    FSM Pires, S Avril, P Livens, JA Cordioli, JJJ Dirckx
    Journal of Biomechanical Engineering 144 (3) 2022

  • 3D finite‐element modeling of vascular adaptation after endovascular aneurysm repair
    S Zhang, JD Laubrie, SJ Mousavi, S Avril
    International Journal for Numerical Methods in Biomedical Engineering 38 (2 2022

  • Stress Analysis in AAA does not Predict Rupture Location Correctly in Patients with Intraluminal Thrombus
    F Lorandon, S Rinckenbach, N Settembre, E Steinmetz, LS Du Mont, ...
    Annals of Vascular Surgery 79, 279-289 2022

  • Patient-Specific Finite Element Modeling of Aneurysmal Dilatation After Chronic Type B Aortic Dissection
    S Zhang, JD Laubrie, SJ Mousavi, SB Ahmed, S Avril
    International Conference on Medical Image Computing and Computer-Assisted 2022

  • Fluid–Structure Interaction Modeling of Ascending Thoracic Aortic Aneurysms in SimVascular. Biomechanics 2022, 2, 189–204
    R Valente, A Mourato, M Brito, J Xavier, A Toms, S Avril
    s Note: MDPI stays neutral with regard to jurisdictional claims in published 2022

  • A thermodynamic framework for unified continuum models for the healing of damaged soft biological tissue
    D Zuo, Y He, S Avril, H Yang, K Hackl
    Journal of the Mechanics and Physics of Solids 158, 104662 2022

  • Patient‐specific computational modeling of endovascular aneurysm repair: State of the art and future directions
    S Avril, MW Gee, A Hemmler, S Rugonyi
    International Journal for Numerical Methods in Biomedical Engineering 37 (12 2021

  • Material characterization of curved shells under finite deformation using the virtual fields method
    P Livens, S Avril, JJJ Dirckx
    Strain 57 (6), e12398 2021

MOST CITED SCHOLAR PUBLICATIONS

  • Overview of identification methods of mechanical parameters based on full-field measurements
    S Avril, M Bonnet, AS Bretelle, M Grdiac, F Hild, P Ienny, F Latourte, ...
    Experimental Mechanics 48 (4), 381-402 2008
    Citations: 809

  • The virtual fields method for extracting constitutive parameters from full‐field measurements: a review
    M Grediac, F Pierron, S Avril, E Toussaint
    Strain 42 (4), 233-253 2006
    Citations: 287

  • Sensitivity of the virtual fields method to noisy data
    S Avril, M Grdiac, F Pierron
    Computational Mechanics 34 (6), 439-452 2004
    Citations: 209

  • General framework for the identification of constitutive parameters from full-field measurements in linear elasticity
    S Avril, F Pierron
    International Journal of Solids and Structures 44 (14-15), 4978-5002 2007
    Citations: 196

  • Identification of elasto-visco-plastic parameters and characterization of Lders behavior using digital image correlation and the virtual fields method
    S Avril, F Pierron, MA Sutton, J Yan
    Mechanics of materials 40 (9), 729-742 2008
    Citations: 174

  • Anisotropic and hyperelastic identification of in vitro human arteries from full-field optical measurements
    S Avril, P Badel, A Duprey
    Journal of biomechanics 43 (15), 2978-2985 2010
    Citations: 157

  • In vitro characterisation of physiological and maximum elastic modulus of ascending thoracic aortic aneurysms using uniaxial tensile testing
    A Duprey, K Khanafer, M Schlicht, S Avril, D Williams, R Berguer
    European Journal of Vascular and Endovascular Surgery 39 (6), 700-707 2010
    Citations: 149

  • Biaxial rupture properties of ascending thoracic aortic aneurysms
    A Duprey, O Trabelsi, M Vola, JP Favre, S Avril
    Acta biomaterialia 42, 273-285 2016
    Citations: 110

  • Stress reconstruction and constitutive parameter identification in plane-stress elasto-plastic problems using surface measurements of deformation fields
    S Avril, F Pierron, Y Pannier, R Rotinat
    Experimental Mechanics 48 (4), 403-419 2008
    Citations: 108

  • Identification of the orthotropic elastic stiffnesses of composites with the virtual fields method: sensitivity study and experimental validation
    F Pierron, G Vert, R Burguete, S Avril, R Rotinat, MR Wisnom
    Strain 43 (3), 250-259 2007
    Citations: 101

  • Experimental identification of a nonlinear model for composites using the grid technique coupled to the virtual fields method
    H Chalal, S Avril, F Pierron, F Meraghni
    Composites Part A: Applied Science and Manufacturing 37 (2), 315-325 2006
    Citations: 101

  • Computational comparison of the bending behavior of aortic stent-grafts
    N Demanget, S Avril, P Badel, L Orgas, C Geindreau, JN Albertini, ...
    Journal of the mechanical behavior of biomedical materials 5 (1), 272-282 2012
    Citations: 93

  • Identification of elasto-plastic constitutive parameters from statically undetermined tests using the virtual fields method
    Y Pannier, S Avril, R Rotinat, F Pierron
    Experimental Mechanics 46 (6), 735-755 2006
    Citations: 93

  • Experimental characterization of rupture in human aortic aneurysms using a full-field measurement technique
    JH Kim, S Avril, A Duprey, JP Favre
    Biomechanics and modeling in mechanobiology 11 (6), 841-853 2012
    Citations: 91

  • In vitro analysis of localized aneurysm rupture
    A Romo, P Badel, A Duprey, JP Favre, S Avril
    Journal of Biomechanics 47 (3), 607-616 2014
    Citations: 86

  • Extension of the virtual fields method to elasto-plastic material identification with cyclic loads and kinematic hardening
    F Pierron, S Avril, VT Tran
    International Journal of Solids and Structures 47 (22-23), 2993-3010 2010
    Citations: 85

  • Identification of heterogeneous constitutive parameters in a welded specimen: uniform stress and virtual fields methods for material property estimation
    MA Sutton, JH Yan, S Avril, F Pierron, SM Adeeb
    Experimental Mechanics 48 (4), 451-464 2008
    Citations: 84

  • Finite element analysis of the mechanical performances of 8 marketed aortic stent-grafts
    N Demanget, A Duprey, P Badel, L Orgas, S Avril, C Geindreau, ...
    Journal of endovascular therapy 20 (4), 523-535 2013
    Citations: 81

  • Patient-specific numerical simulation of stent-graft deployment: Validation on three clinical cases
    D Perrin, P Badel, L Orgas, C Geindreau, A Dumenil, JN Albertini, S Avril
    Journal of Biomechanics 48 (10), 1868-1875 2015
    Citations: 79

  • Novel methodology for characterizing regional variations in the material properties of murine aortas
    MR Bersi, C Bellini, P Di Achille, JD Humphrey, K Genovese, S Avril
    Journal of biomechanical engineering 138 (7), 071005 2016
    Citations: 76