Nissa Nurfajrin Solihat
@brin.go.id
Research Center Biomass and Bioproducts
National Research and Innovation Agency
Young researcher with 5+ years of experiences at prestigious research institution. Looking for Ph.D supervisor who works in biomass valorization and its derivatives such as lignin research.
EDUCATION
2017-2019 Master's degree from Kyungpook National University, South Korea
2007-2012 Bachelor's degree from Diponegoro University, Indonesia
RESEARCH INTERESTS
My research interest is the entire value chain, from lignocellulosic biomass separation to the valorization of isolated biopolymers, with the goal of creating commodities comparable to fossil-based products in a sustainable manner.
FUTURE PROJECTS
BIOMASS VALORIZATION TO PRODUCE SUBSTANCES ANALOGOUS TO FOSSIL-BASED COMMODITIES
Indonesia is an archipelago country that contains a lot of variety of biomass, either as waste or commodities. Biomass or lignocellulosic compound consists of cellulose, hemicellulose, lignin, extractives/volatiles, and ash. Biomass fractionations determine the compound structure because severe pretreatment brings damage to cellulose or lignin structure. This research aims to get lignin fractions from biomass to produce a unique functionalized platform of lignin molecules without damaging their structure. Furthermore, lignin is isolated from the black liquor and subject to depolymerization step to obtain renewable flatform chemicals. These obtained chemicals such as aromatic and furanic can be used for many products such as bio-fuels, plastic, pharmaceutical, and many others
Applications Invited
PhD supervisor
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Kifayati Rosiyanti Dewi, Maya Ismayati, Nissa Nurfajrin Solihat, Nancy Dewi Yuliana, Feri Kusnandar, Handy Riantana, Heryani Heryani, Abdul Halim, Thamina Acter, Nizam Uddin,et al.
Springer Science and Business Media LLC
AbstractThe halal food industries are rapidly expanding to fulfill global halal demands. Non-halal substances such as porcine proteins are often added intentionally or unintentionally to products. The development of highly selective and sensitive analytical tools is necessary, and liquid chromatography–mass spectrometry is a powerful tool that can cope with the challenge. The LC–MS method has great potential for halal authentication, because it has high sensitivity and low detection limit and detects several species markers and different tissue origins at once within one species. This article provides an understanding of recent advances in the application of LC–MS for the improvement of porcine authentication. Sample preparation, marker selection, separation and mass spectrometry conditions, quantitative assessment, and data processing for protein identification were all covered in detail to choose the most suitable method for the analytical needs.
Azizatul Karimah, Nissa Nurfajrin Solihat, Novitri Hastuti, Maya Ismayati, Riksfardini Anissa Ermawar, Asma Sohail, Apri Heri Iswanto, Harits Atika Ariyanta, R. A. Ilyas, Rudi Dungani,et al.
Springer Science and Business Media LLC
Nissa Nurfajrin Solihat, Dwi Ajias Pramasari, Raden Permana Budi Laksana, Witta Kartika Restu, Muhammad Ghozali, Evi Triwulandari, Widya Fatriasari, and Takashi Watanabe
Elsevier BV
Rafiqul Alam, Raisul Awal Mahmood, Syful Islam, Fenny Clara Ardiati, Nissa Nurfajrin Solihat, Md Badrul Alam, Sang Han Lee, Dede Heri Yuli Yanto, and Sunghwan Kim
Elsevier BV
Meldana Lumbanraja, Nissa Nurfajrin Solihat, Dewi Sondari, Riska Surya Ningrum, Dwi Ajias Pramasari, Euis Hermiati, Bambang Nurhadi, Yusuf Wibisono, and Riksfardini Annisa Ermawar
AIP Publishing
Adik Bahanawan, Yeyen Nurhamiyah, Nissa Nurfajrin Solihat, Widya Fatriasari, Petar Antov, and Seng Hua Lee
Informa UK Limited
Mayang Aristika Jayanti, Ady Ardhana, Naurotul Husna, Azizatul Karimah, Muslimatul Rahmi DN, Harits Atika Ariyanta, Eko Budi Santoso, Muhammad Rasyidur Ridho, Nissa Nurfajrin Solihat, Petar Antov,et al.
Springer Science and Business Media LLC
Sri Hidayati, Sutopo Hadi, Saputra, Apri Heri Iswanto, Widya Fatriasari, Nissa Nurfajrin Solihat, Petar Antov, and Lee Seng Hua
Springer Science and Business Media LLC
Widya Fatriasari, Nissa Nurfajrin Solihat, Fahriya Puspita Sari, Azizatul Karimah, and Asma Sohail
Springer Nature Singapore
Sri Hidayati, Eugenia Fonny Budiyanto, Hadi Saputra, Sutopo Hadi, Apri Heri Iswanto, Nissa Nurfajrin Solihat, Petar Antov, Lee Seng Hua, Widya Fatriasari, and Mohd. Sapuan Salit
Computers, Materials and Continua (Tech Science Press)
Samsul Bhakri, Muhammad Ghozali, Edy Cahyono, Evi Triwulandari, Witta Kartika Restu, Nissa Nurfajrin Solihat, Apri Heri Iswanto, Petar Antov, Viktor Savov, Lee Seng Hua,et al.
Computers, Materials and Continua (Tech Science Press)
Nissa Nurfajrin Solihat, Alif Faturahman Hidayat, Mohamad Nurul Azman Mohammad Taib, M. Hazwan Hussin, Seng Hua Lee, Muhammad Aizat Abd Ghani, Syeed SaifulAzry Osman Al Edrus, Henri Vahabi, and Widya Fatriasari
Springer Science and Business Media LLC
Nissa Nurfajrin Solihat, Seungwoo Son, Elizabeth K. Williams, Matthew C. Ricker, Alain F. Plante, and Sunghwan Kim
Elsevier BV
Erika Ayu Agustiany, Muhammad Rasyidur Ridho, Muslimatul Rahmi D. N., Elvara Windra Madyaratri, Faizatul Falah, Muhammad Adly Rahandi Lubis, Nissa Nurfajrin Solihat, Firda A. Syamani, Petro Karungamye, Asma Sohail,et al.
Wiley
M. Hazwan Hussin, Jimmy Nelson Appaturi, Ng Eng Poh, Nur Hanis Abd Latif, Nicolas Brosse, Isabelle Ziegler-Devin, Henri Vahabi, Firda Aulya Syamani, Widya Fatriasari, Nissa Nurfajrin Solihat,et al.
Elsevier BV
Nissa Nurfajrin Solihat, Eko Budi Santoso, Azizatul Karimah, Elvara Windra Madyaratri, Fahriya Puspita Sari, Faizatul Falah, Apri Heri Iswanto, Maya Ismayati, Muhammad Adly Rahandi Lubis, Widya Fatriasari,et al.
MDPI AG
The efficient isolation process and understanding of lignin properties are essential to determine key features and insights for more effective lignin valorization as a renewable feedstock for the production of bio-based chemicals including wood adhesives. This study successfully used dilute acid precipitation to recover lignin from black liquor (BL) through a single-step and ethanol-fractionated-step, with a lignin recovery of ~35% and ~16%, respectively. The physical characteristics of lignin, i.e., its morphological structure, were evaluated by scanning electron microscopy (SEM). The chemical properties of the isolated lignin were characterized using comprehensive analytical techniques such as chemical composition, solubility test, morphological structure, Fourier-transform infrared spectroscopy (FTIR), 1H and 13C Nuclear Magnetic Resonance (NMR), elucidation structure by pyrolysis-gas chromatography-mass spectroscopy (Py-GCMS), and gel permeation chromatography (GPC). The fingerprint analysis by FTIR detected the unique peaks corresponding to lignin, such as C=C and C-O in aromatic rings, but no significant differences in the fingerprint result between both lignin. The 1H and 13C NMR showed unique signals related to functional groups in lignin molecules such as methoxy, aromatic protons, aldehyde, and carboxylic acid. The lower insoluble acid content of lignin derived from fractionated-step (69.94%) than single-step (77.45%) correlated to lignin yield, total phenolic content, solubility, thermal stability, and molecular distribution. It contradicted the syringyl/guaiacyl (S/G) units’ ratio where ethanol fractionation slightly increased syringyl unit content, increasing the S/G ratio. Hence, the fractionation step affected more rupture and pores on the lignin morphological surface than the ethanol-fractionated step. The interrelationships between these chemical and physicochemical as well as different isolation methods were investigated. The results obtained could enhance the wider industrial application of lignin in manufacturing wood-based composites with improved properties and lower environmental impact.
Dede Heri Yuli Yanto, Sita Heris Anita, and Nissa Nurfajrin Solihat
Informa UK Limited
Widya Fatriasari, Muhammad Rasyidur Ridho, Azizatul Karimah, Sudarmanto, Ismadi, Yusup Amin, Maya Ismayati, Muhammad Adly Rahandi Lubis, Nissa Nurfajrin Solihat, Fahriya Puspita Sari,et al.
Informa UK Limited
Thamina Acter, Nizam Uddin, Nissa Nurfajrin Solihat, and Sunghwan Kim
American Chemical Society (ACS)
Nissa Nurfajrin Solihat, Rika Raniya, Triyani Fajriutami, Apri Heri Iswanto, Widya Fatriasari, and Ahmad Fudholi
BioResources
Sweet sorghum bagasse (SSB) is potential feedstock for bioethanol production due to its natural abundance and high cellulose content (> 40%). This work compared the impact of three variables relative to the enzymatic hydrolysis of SSB kraft pulp. The three variables were the biosurfactant from lignin derivative known as amphiphilic lignin derivatives (A-LD), the enzyme loading level, and the hydrolysis time. These variables were optimized by response surface methodology (RSM) with a Box-Behnken design (BBD). The concentration of polyethylene glycol (PEG) 4000 was also optimized to compare it with the A-LD performance in the enzymatic hydrolysis process. After optimization, the A-LD produced a higher reducing sugar yield (RSY) (99.45%) than the PEG 4000. The difference in the predicted versus experimental values of the RSY was less than 4%, which means that the model was highly predictive. The adequacy of the model was confirmed by a regression value close to 1 for the A-LD assisted test. The result implies that the A-LD significantly improved the enzymatic hydrolysis performance to enhance the RSY. Moreover, the BBD is adequate and useful to identify the optimum concentration of surfactant.
Rafiqul Alam, Fenny Clara Ardiati, Nissa Nurfajrin Solihat, Md Badrul Alam, Sang Han Lee, Dede Heri Yuli Yanto, Takashi Watanabe, and Sunghwan Kim
Elsevier BV
R C B Ginting, N Solihat, A R Hafsari, and Irawan
IOP Publishing
Eunji Cho, Nissa Nurfajrin Solihat, Young Hwan Kim, and Sunghwan Kim
American Chemical Society (ACS)
In this work, comprehensive lists of internal calibrants for accurate mass determination of molecules in crude oils, natural organic matter, and soil as well as their preparation recipes are presented. The lists include various sets of chemicals for positive- and negative-ion mode electrospray ionization, atmospheric pressure chemical ionization, atmospheric pressure photoionization, and laser desorption ionization. The chemicals were chosen based on their solvent compatibility, ionization efficiency, and accessibility. The sample preparation process was optimized for each ionization method and type of sample. The lists include detailed information on preparation solvent, concentrations, and mixing ratios of sample and calibrants. Internal calibration using the information in the lists results in successful calibration, and all the data presented in this study show root-mean-square errors between the theoretical and obtained m/z numbers of less than 0.4 ppm. The information presented in this study provides an important guideline for researchers working on complex mixtures with ultrahigh-resolution mass spectrometry.
H. Vahabi, N. Brosse, N.H. Abd Latif, W. Fatriasari, N.N. Solihat, R. Hashim, M. Hazwan Hussin, F. Laoutid, and M.R. Saeb
Elsevier
N N Solihat, E Hermiati, and D T N Adi
IOP Publishing
Abstract The depletion of fossil fuel is intriguing for researchers to find sustainable energy. Oil palm empty fruit bunch (OPEFB) is abundant biomass in Indonesia which is potential to be converted into bioethanol because of its high cellulose content. Suitable pre-treatment could increase the effectiveness of cellulose conversion into sugars. The aim of this study is to evaluate the effectiveness of Microwave-assisted Oxalic Acid pre-treatment (MOxA) and Enzymatic Hydrolysis (EH) to improve enzyme accessibility through variation of heating temperature, irradiation time, and EH incubation time. The higher the microwave heating temperature, longer irradiation time, and longer EH incubation time, the higher the glucose yield per pulp (GY) and reducing sugar yield (RSY) were observed. After MOxA at 200°C-15 min, as much as 43.22 % GY per initial biomass was obtained by EH for 10 days. SEM images showed more ruptures on the surface area of OPEFB fibre after MOxA that supported in increasing of enzyme digestibility. The XRD spectra demonstrated that the crystallinity index (CI) increased after MOxA because pre-treatment reduced amorphous components in the biomass. In addition, the FTIR spectra showed that peak intensity at 1714 cm−1 corresponded to hemicellulose was gradually reduced after MOxA while peaks corresponded to lignin was more discernible.
RECENT SCHOLAR PUBLICATIONS
MOST CITED SCHOLAR PUBLICATIONS
GRANT DETAILS
Last 3 years:
1. Valorization of lignin from pulp industry by-product as antimicrobial agent for natural fiber textile (2021-present) (BRIN/LIPI, Indonesia) - Project Leader
2. Utilization of Biomass Wastes for Functional Materials and Chemicals (2021-present) (JASTIP, Japan)-Member
3. Development of digital information system and identification system of natural fiber as sources of textile fiber (2020-2021) (Ministry of Finance Indonesia) - Member
4. Lignin and Tannin-Based Polyurethane Resin for fire resistant rami fiber (2020-2021) (Ministry of Finance Indonesia) - Member
5. Japan-ASEAN Science, Technology and Innovation Platform of Sustainable Development Research (2020) (JASTIP, Japan) - Member
6. Integrated Biorefinery of Sugarcane Trash (2020) (E-Asia, Japan) - Member
7. Development of Lignin-Based Biomaterials For Environmentally Friendly Adhesives, Mortar Additives, and Gold Emulsifiers (2020) (BRIN/LIPI, Indonesia) - Member
8. Isolation, Screening and Assessment of White Rot Fungi in Berbak and Sembilang Biosphere Reserve for Their Potency in Wastewater Treatment (2019-2020) (MAB UNESCO) -Member
RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)
Patent last 3 years:
No Judul Tahun
1. Produk Vinir Kayu Laminasi Tipis Tanpa Perekat 2022
2. Paten Granted IDP00007234 : Biosurfaktan Turunan Lignin Dan Proses Pembuatannya 2021
3. Metode Klasifikasi Jenis Serat Alam dengan Menggunakan Augmentasi Data Dan Deep Neural Network (DNN) 2021
4. Metode Ekstraksi Lignin Daun Tebu Menggunakan Enzim Selulase Dan Dioksan Serta Produk Yang Dihasilkannya 2021
5. Metode Pemisahan Lignin Dari Lindi Hitam Sisa Produksi Pulp 2021
6. Metode Ekstraksi Lignin Daun Tebu Menggunakan Asam Konsentrasi Rendah Dan Produk Yang Dihasilkannya 2021
7. Biosurfaktan Anionik Berbasis Lignin Alkali dan Proses Pembuatannya 2020
8. Proses Pembuatan Perekat Kayu Lapis Non- Formaldehida Berbahan Dasar Pati Dialdehida Dan Produk Yang Dihasilkannya. 2020
9. Formulasi biosurfaktan amphipilic lignin derivatives (A-LD) dari lignin Acacia mangium, penggunaan dan proses pembuatannya 2017
10. Produk Biosurfaktan Turunan Lignin dan Proses Pembuatannya. 2017
Industry, Institute, or Organisation Collaboration
Kyungpook National University
PT. Greenei Indonesia
Nauli Ecoprint
INDUSTRY EXPERIENCE
PT Ogawa Indonesia